* Corrosive Haze followed by Slithereen Crush takes advantage of Alchemist's main weakness, being physical damage before he has the change to improve his surviability with items.
* Bash of the Deep will deal lots of damage during the laning phase.
Additional:
* Alchemist has a low starting armor and a low agility growth, which translates to a low armor growth . And since it is very uncommon for Alchemist to get straight to Assault Cuirass, or Shiva's Guard, Corrosive Haze makes him too vulnerable to physical damage, even with the hp regeneration of Chemical Rage

* Corrosive Haze grants vision of Monkey King, even when he is in the trees.

* Untouchable greatly reduces Chemical Rage's attack speed advantage.

* Impetus pure damage ignores the extra armor granted from Wukong's Command.
* Enchant can dispel Monkey King's Jingu Mastery bonuses.
* Untouchable makes it hard for Monkey King to land Jingu Mastery stacks.
* Sproink allows Enchantress to escape from Wukong's Command.

* Reaper's Scythe can kill Alchemist before Chemical Rage has the time to heal him.
* Ghost Shroud can prevent Alchemist from attacking Necrophos, as well as make him immune to Acid Spray and Unstable Concoction damage.
* Heartstopper Aura will do damage as long as Necrophos is alive based on health percentage, which is a problem for a strength hero such as Alchemist.

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

* {U:Familiar}s have flying vision. They can be used to scout Monkey King when he is in the tree.
* Stone Form can destroy the tree Monkey King is standing on.

* Visage can quickly kill heroes with low to medium base armor and no innate escape mechanism. Examples include Alchemist, Crystal Maiden and Zeus.

* Viper can bully Alchemist out of mid lane quite easily, forcing him to either retreat into jungle, or stay harassed in lane, and get very few last hits. Vipers break also completely disables Greevil's greed which prevents Alchemist to earn his amazing amounts of money.

* Nethertoxin prevents the buildup of Jingu Mastery stacks.
* Viper's poison magical damage-over-time stops Monkey King from using Tree Dance. It also ignores the extra armor bestowed by Wukong's Command.
Additional:
* Nethertoxin prevents the buildup of Jingu Mastery stacks.
* Monkey King's high base movement speed is of little worth against the array of slows Viper possesses.
* All of Viper's magical damage over time stops Monkey King from using Tree Dance. It also ignores the extra armor bestowed by Wukong's Command.

* Alchemist's reliance on fast attack speed to do single-target damage makes him vulnerable to Static Link. It also goes through Black King Bar, which is a standard item on Alchemist.
* Eye of the Storm is great against high health strength heroes as it reduces their survivability to physical damage.
* Razor has early lane push to counter Acid Spray.

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

Additional:
* Static Link can steal the bonus damage from Jingu Mastery and reduce the physical damage from Boundless Strike. It also reduces Wukong's Command's damage if it's used after stealing damage via Static Link.
* Static Link will give Razor shared vision on Monkey King if he tries to escape using Tree Dance or ​Mischief.
* Plasma Field can prevent Monkey King from using Tree Dance and Mischief.
* Eye of the Storm will remove the armor buff from Wukong's Command, as well as hitting Monkey King during Mischief.

* Quas-Exort Invoker can win the mid lane easily against Alchemist because Quas regeneration will nullify Acid Spray's damage over time and Exort damage bonus will allow Invoker to out last hit Alchemist.

* Heroes with long animations can be frequently interrupted with Cold Snap: Earthshaker, Monkey King, Shadow Fiend Lina

* Heroes who rely on skills to become a heavy hitter in a certain amount of time can waste their timing because of a lucky Lucky Shot's disarm: Terrorblade, Sven, Clinkz, Windranger, Alchemist, Dragon Knight, Legion Commander

* Rolling Thunder allows Pangolier to quickly clear trees.

* Shadow Dance allows Slark to not be targeted by Unstable Concoction, making Alchemist stun himself and making himself vulnerable to the enemy.
* Dark Pact also allows him to just purge off the stun if timed correctly.
* Essence Shift will steal stats over long durations at a time should Alchemist lack the damage to kill Slark.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* She can easily cancel Wukong's Command with Nether Swap.
* Wave of Terror can also detect him while he's on the trees.
Additional:
* Wave of Terror grants flying vision over trees, and its wide effect can hit Monkey King and end Mischief.
* Nether Swap can easily cancel Wukong's Command by swapping him out of the circle.

* Power Cogs pushes Monkey King out of Wukong's Command, ending his ultimate.
* Rocket Flare allows Clockwerk to scout Monkey King in the trees, and chase him with Hookshot.
Additional:
* Rocket Flare ends Mischief, and reveals Monkey King on the treetops.
* Hookshot can catch Monkey King when he retreats to the treeline.

* Venomancer's magical damage-over-time poisons will constantly put Tree Dance on cooldown, greatly diminishing Monkey King's mobility.
* Venomous Gale and Poison Nova will hit Monkey King when he is perched on a tree, or disguised with Mischief.
* However, Venomancer is also easily ganked by Monkey King if caught by surprise.
Additional:
* Venomancer's magical damage-over-time poisons putting Tree Dance on cooldown, greatly diminishing Monkey King's mobility.
* Venomous Gale and Posion Nova will hit Monkey King when he is perched on a tree, or disguised by Mischief.

* Chaotic Offering can destroy the tree Monkey King is standing on.
* Shadow Word and Fatal Bonds constantly puts Tree Dance on cooldown.

* Malefice keeps Tree Dance on cooldown, and can interrupt Wukong's Command's long cast time.
* Midnight Pulse destroys a large amount of trees.
Additional:
* Malefice will cause Monkey King to struggle without Black King Bar, as its periodic damage and stun disables/interrupts abilities, such as Tree Dance and Wukong's Command.
* Midnight Pulse also destroys trees in a wide radius, stunning Monkey King if he happened to be on a tree caught within that AoE.

* Shadow Realm makes it hard for Monkey King to land Jingu Mastery stacks. It also allows Dark Willow to escape from Wukong's Command.
* Terrorize can easily end Wukong's Command by forcing him to move out of the circle.
Additional:
* Terrorize forces Monkey King out of Wukong's Command.

* Beastmaster's Hawk can find Monkey King easily while he is sitting on tree.
* Beastmaster's Wild Axes can knock out Monkey King from tree.
* Beastmaster's Boars drastically reduce Monkey King's attack speed, making it harder for him to gain Jingu Mastery stacks.
Additional:
* Wild Axes can chop down trees, making it difficult for Monkey King to utilize Tree Dance well.
* Call of the Wild Hawk can scout Monkey King when he is perched on top of trees.

* Ball Lightning allows Storm Spirit to destroy a large amount of trees, negating Tree Dance. It also makes it easy to avoid Wukong's Command and Boundless Strike.
Additional:
* Ball Lightning allows Storm Spirit to easily catch up to Monkey King, destroying a large number of trees, cancelling Tree Dance, and causing Monkey King to be stunned in the process.

* Charge of Darkness keeps vision of Monkey King, even when he is in the trees.
* Nether Strike locks onto Monkey King and focuses damage on him during Wukong's Command.

* Keeping Void Spirit inside Wukong's Command is a very tricky task, especially in the early and mid game. In addition, if Monkey King is in a bad position, a well placed Aether Remnant can easily pull him out of the ring.
* Getting stacks of Jingu Mastery can be difficult when attacking Void Spirit.

* Ice Blast cancels out Chemical Rage's rapid health regeneration. It can also take advantage of Alchemist's Armlet of Mordiggian toggling, as it will make HP drain insanely fast, essentially killing the bearer in no time.
Additional:
* Ice Blast nullifies the health regeneration granted by Chemical Rage, which Alchemist greatly relies on to stay alive in battle.
* Alchemist tends to build Armlet of Mordiggian which can be deadly during Ice Blast.

* Boulder Smash can smash Monkey King out of the Wukong's Command radius.
* Rolling Boulder destroys trees and helps Earth Spirit close the gap between him and Monkey King.

* Monkey King's natural reliance on trees makes him an exceptionally prime target for Spear of Mars. Should Monkey King use Mischief to disguise himself, it will still hit him, stunning him in the process.
* God's Rebuke easily pushes Monkey King out of Wukong's Command.

* Thunder Strike provides vision of Monkey King when he's in the trees. The periodic damage will also keep Monkey King from using Tree Dance if he's on the ground.
* Glimpse pulls Monkey King out of the trees if he attempts to escape using Tree Dance, and can cause Wukong's Command to end prematurely if Monkey King is Glimpsed out of its radius.
* Kinetic Field and Static Storm can be used to hold Monkey King in place and ensure a kill.

* Cinder Brew and Drunken Brawler makes it hard for Monkey King to stack Jingu Mastery.
* Cyclone can remove Monkey king for 6 seconds if his allies lack dispels.
* Dispel Magic can dispel Jingu Mastery's bonuses.

* Blur makes it hard for Monkey King to stack Jingu Mastery.
* Phantom Strike allows Phantom Assassin to blink directly to Monkey King during Wukong's Command, bypassing all his clones.
* Coup de Grace's high damage can kill Monkey King quickly, thus ending Wukong's Command prematurely.

* Blink allows Queen of Pain to avoid ganks and keep her distance, preventing Monkey King from building up Jingu Mastery.
* Scream of Pain and Sonic Wave will hit Monkey King when he is disguised, or on a tree.
* The large AoE and low cooldown also helps Queen of Pain hit the real Monkey King inside of Wukong's Command.

* Proximity Mines and Stasis Traps can be placed near trees to detect Monkey King.
* Follow up with Blast Off! to destroy the tree, causing Monkey King to take high damage, fall from the tree, and become stunned.
Additional:
* Techies can turn his tree jumping ability against him, by placing Proximity Mines/Stasis Traps that will detect him near trees, and then destroying the trees around him with Blast Off!, stunning him and dealing high damage, on top of him being silenced when the stun expires.
* Monkey King's mobility is also severely limited around Techies' mines as he will almost always trigger them due to the cooldown time between tree jumps. Monkey King will be forced to take mine damage or escape with Primal Spring.

* Light Strike Array destroys the tree Monkey King is standing on.
* Lina's Laguna Blade high damage burst can kill Monkey King before he has Jingu Mastery bonuses.

* Tusk can Walrus Kick Monkey King from Wukong's Command. Making his ultimate useless.

* Chemical Rage will rarely save Alchemist against Ursa's Fury Swipes.
* Enrage allows Ursa to both be a threat to Alchemist and avoid his over time damage.

* Tidebringer will deal lots of damage to Alchemist before he builds physical survivability items.
* Torrent and X Marks the Spot can control Alchemist at all stages of the game before he has Black King Bar.
* Ghostship's rum buff will greatly reduce the Alchemist's damage output in teamfights including his Radiance.

* Alchemist is a well-known Radiance carrier among other auras your illusions will benefit from. They also get the extra move speed and reduced base attack time from his Chemical Rage, and it's even better if you can catch him as his own rage is about to expire.
* Disruption will buy enough time for all allies to retreat when Alchemist starts to activate Unstable Concoction.

* Ember's magic damage build is able to burst down Alchemist due to his low strength gain and Alchemist's normal item pick up.

* Firefly allows Batrider to gain vision of Monkey King while he is on an tree, as well as destroying any nearby trees, denying Monkey King spots to jump to, or causing him to fall.
* Sticky Napalm's turn rate slow makes it significantly more difficult for Monkey King to jump from tree to tree and gain Jingu Mastery stacks. It also reveals Monkey King while he is on a tree.
* Flamebreak and Flaming Lasso enable Batrider to remove Monkey King out of Wukong's Command.
Additional:
* Firefly destroys trees and can turn Tree Dance into a free four second stun.

* Blinding Light can easily push Monkey King out of Wukong's Command, as well as blinding him.
* Will-O-Wisp destroys trees in a massive area, damaging Monkey King's mobility
* However, Keeper of the Light can be easily ganked by Monkey King during early-mid game stage.
Additional:
* Blinding Light can knock Monkey King outside of his ultimate, Wukong's Command or can generally blind him effectively.
* Will-O-Wisp stun Monkey King from Tree Dance by destroying his tree.

* Clinkz can use Burning Army in teamfights which will cause a problem for Alchemist.

* Zeus is good against heroes that juke in trees or up cliffs, like Batrider, Monkey King, Spectre, and Tinker, by providing vision in any area with Lightning Bolt, or guaranteeing vision on enemies with Thundergod's Wrath.

* Heroes that can maintain vision on Monkey King can see when he uses Tree Dance: Bloodseeker, Treant Protector with Eyes In The Forest, Sniper, Weaver

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Pugna's Decrepify makes sure that either Alchemist is unable to hit anyone while also being slowed and susceptible to magical damage, or can protect an ally from physical attacks. Besides, Pugna can push early on, when Alchemist is not strong enough to repel it, so by the time Alchemist comes online, he might be forced to sit in base.

* Monkey King is also hindered by Track since he relies on trees to hide him from vision.

Additional:
* Track grants vision of Monkey King, even when he's in the trees.

* Other heroes that rely on physical attacks to deal damage and not their abilities: Troll Warlord, Sniper, Monkey King, Sven.

Additional:
* Powershot destroys the tree Monkey King is standing on.
* Monkey King's natural reliance on trees makes him an easy target for Shackleshot.
* Windrun evades Monkey King's attacks, preventing him from building up Jingu Mastery.

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

* Heroes that can keep Monkey King stunned for a long time can pose a threat: Axe, Centaur Warrunner.

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

* Heroes that can keep Monkey King stunned for a long time can pose a threat: Axe, Centaur Warrunner.

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

* Melee heroes that get kited easily have hard times dealing with Puck without any lockdowns, as Puck is one of the most mobile heroes. Heroes like Sven, Lifestealer, Ursa and Alchemist may have problems to get to Puck without proper initiation items. They also lack reliable lockdowns, as their disables are easily avoidable for Puck, or are just a soft disable.

* Heroes that can maintain vision on Monkey King can see when he uses Tree Dance: Bloodseeker, Treant Protector with Eyes In The Forest, Sniper, Weaver

* Feast is good against high health strength heroes such as Alchemist.
* Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.