* Ice Blast cancels out Chemical Rage's rapid health regeneration. It can also take advantage of Alchemist's Armlet of Mordiggian toggling, as it will make HP drain insanely fast, essentially killing the bearer in no time.
Additional:
* Ice Blast nullifies the health regeneration granted by Chemical Rage, which Alchemist greatly relies on to stay alive in battle.
* Alchemist tends to build Armlet of Mordiggian which can be deadly during Ice Blast.

* Shadow Dance allows Slark to not be targeted by Unstable Concoction, making Alchemist stun himself and making himself vulnerable to the enemy.
* Dark Pact also allows him to just purge off the stun if timed correctly.
* Essence Shift will steal stats over long durations at a time should Alchemist lack the damage to kill Slark.

* Ice Blast prevents Lifestealer from lifestealing and healing with Infest in fights.

* Dark Pact can be used to remove Open Wounds.
* Shadow Dance allows Slark to attack Lifestealer for its duration without any way for Lifestealer to fight back.
* Slark commonly buys a Silver Edge, which can break Lifestealer's Feast, severely diminishing his damage output and lifesteal.

* Arctic Burn and Splinter Blast debuffs are dispellable with Dark Pact. Arctic Burn is also no escape against Pounce.
* Cold Embrace just gives Slark free Essence Shift stacks. He also relies mostly on magic damage early in the game.

* Cold Embrace makes its target immovable, allowing Ancient Apparition to easily land Ice Blast, or a Cold Feet stun
* Ice Blast also negates healing from Cold Embrace
Additional:
* Ice Blast disables the healing component of Cold Embrace, making it essentially a 4 second stun on an ally and a perfect setup for Ice Blast.
* If Cold Feet is cast on an enemy hero affected by Cold Embrace, it will almost guarantee the enemy comes out stunned.

* Ice Blast nullifies the healing from {U:Warlock Golem} and Shadow Word.
* Cold Feet stuns Warlock if he chooses to continue channeling Upheaval.

* Upheaval does not interrupt Slark too much, as he can just Pounce out of the area.
* Fatal Bonds and Shadow Word can be dispelled by Dark Pact.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Ice Blast stops Attribute Shift (Strength Gain) from recovering additional health, and using it will even bring Morphling closer to the shatter threshold.
* In lane, Ice Vortex slows Morphling's already poor movement speed to a crawl; this, coupled with the amplification of magic damage, can set up an early kill on Morphling if Ancient Apparition has a suitable lane partner.

* Slark is a natural Shadow Blade carrier, and with Pounce Sniper has no opportunity to escape or react.
* With Essence Shift and Shadow Dance, Slark will easily win a fight against Sniper.
Additional:
* Sniper is one of the most gankable heroes in the game, and has no defenses when Pounced on by Slark.

* Slark can detect early Roshan attempts due to Shadow Dance if he frequently checks the Pit.
* Enrage cannot restore attributes stolen by Essence Shift and will reduce his physical damage output.
* Even if Ursa initiates with Earthshock, Slark can Pounce away or use Dark Pact after Ursa's initiation to avoid Fury Swipes' damage until Earthshock's slow is gone.

* Medusa cannot chase Slark in any way and has no disable beyond her ultimate, making her unable to stop him getting away and regenerating before coming back to finish her off.
* Essence Shift removes 1 of every attribute, lowering Medusa's mana pool's cap and leaving her much more vulnerable in prolonged fights.
Additional:
* Medusa is especially vulnerable to Essence Shift, as both strength and intelligence contribute to her effective HP, while agility contributes to her damage.
* Dark Pact when timed right can be used to dispel Stone Gaze right after it petrifies Slark, allowing him to keep attacking Medusa throughout the duration.

* Dark Pact, if timed correctly, can dispel Wraithfire Blast's stun and slow.
* Since Wraith King has a lot of health and multiple lives, Slark can keep gaining Essence Shift stacks, increasing armor, damage, and attack speed and can beat down Wraith King twice.
* Slark sometimes carries Diffusal Blade to burn mana as an attempt to shut down Reincarnation.
* Because Wraith King has no AoE abilities, Shadow Dance is particularly useful against Wraith King.

* Dark Pact dispels Dismember if timed perfectly.
* Pudge's low attack speed and poor agility can be lowered even further by Essence Shift.
* Shadow Dance grants Slark invisibility and a high degree of mobility, which can make Slark a difficult target to hook and also protects him from Pudge's Dismember (including allies with an Aghanim's Scepter).

* Pounce and Dark Pact together with some attacks can gank Rubick down quickly. Rubick can seldom retaliate because of the strong dispel of Dark Pact. What is more, Rubick is the type of squishy support that Slark exactly wants to gank.
* Though Shadow Dance is a great spell to steal, Slark's untargetable nature and his low cooldown spells prevents Rubick from stealing it.
* Slark usually builds Diffusal Blade which can prevent Rubick to cast his abilities from Spell Steal.

* Ice Blast, Cold Feet, and Ice Vortex are easier to land on Snapfire while she channels her Mortimer Kisses.
Additional:
* Snapfire is vulnerable while she is casting Mortimer Kisses making her an easy target for the effects of Cold Feet and Ice Blast.

* Dark Pact easily purges away both slow and disarm effect from Lucky Shot.
* With Pounce now apply leash to the target, Pangolier is helpless against Slark since both his Swashbuckle and Rolling Thunder will be disabled. Pounce also help Slark to easily escape from Rolling Thunder.

* Cold Feet and Ice Vortex both hinder Dragon Knight's movement greatly during teamfights.
* Ice Blast ignores Dragon Knight's armor and kills him prematurely.

* Pounce's root prevents Earth Spirit from using Rolling Boulder to escape, making it easier for Slark to shut him down especially in the laning phase.

* Pounce prevents Tinker from blinking away.
* Slark frequently builds Shadow Blade, which allows him to approach Tinker unnoticed. Since Tinker's farming usually covers a significant amount of area on the map, Sentry Wards may not be cost effective.
* Shadow Dance allows Slark to detect both common and unusual wards. Eliminating common ward causes Tinker trouble farming many lanes if he does not know who may be waiting to jump on him. Slark is also uniquely able to identify some of the less common wards used by Tinker, such as those placed on the cliffs at map edges which Tinker uses to give him vision over the trees he uses to hide in.
* Slark's extremely high move speed from Shadow Dance, potentially stacked with Shadow Blade, allows him to easily follow Tinker between lanes, especially if Tinker has pushed the lanes out.
* Dark Pact dispels Laser's blind.

* Ice Blast prevents Io from healing the target.
Additional:
* Ice Blast prevents Io from healing an ally with Tether and prevents healing from Overcharge
* Io is a common Mekansm builder which is useless if he is affected by Ice Blast.

* Dark Pact can dispel Venomous Gale and Poison Sting.
* Shadow Dance allows Slark heightened regeneration when out of vision making DoTs effects less threatening.

* Ice Blast prevents Huskar from healing, regeneration, health gained from activating an Armlet of Mordiggian and will kill him when his health dips below a threshold. This makes it very dangerous for him to use his abilities.
Additional:
* Ice Blast prevents Huskar from healing with Berserker's Blood and negates any lifesteal, making him significantly weaker in battle.
* Burning Spear and Life Break cost Huskar his own health, killing him under the effects from Ice Blast.
* Huskar often builds Armlet of Mordiggian which can be deadly during Ice Blast.

* Ice Blast prevents healing from Hand of God.
Additional:
* Ice Blast prevents Divine Favor and Hand of God from healing his allies or himself.

* Ice Blast completely nullifies any healing, making Necrophos unable to stay in a teamfight to sustain his teammates (and himself) or deal gradual damage to the enemy, else he be faced with a quick death if focused on.

* Dark Pact dispels debuffs from Gush, Anchor Smash and even Ravage if timed correctly.
* Kraken Shell cannot restore attributes stolen by Essence Shift or dispel the leash if he gets Pounced.

* Flux is dispelled by Dark Pact.
* Pounce allows Slark to avoid Spark Wraiths.
* Tempest Double allows Slark to build up Essence Shift stacks, especially when it is being used for split pushing.

* Dark Pact dispels Ignite's slow and Fireblast's stun.
* Shadow Dance allows Slark to regenerate HP, even when he is affected by Ignite and Fireblast.

* A well-timed Dark Pact can dispel Frost Arrows and Gust, letting Slark engage and escape freely.
* Shadow Dance lets Slark quickly close the gap and deal heavy damage without giving Drow Ranger a chance to retaliate.
* Pounce counteracts Frost Arrows' slow, letting Slark easily pin Drow Ranger down or flee.
Additional:
* Pounce and items like Shadow Blade makes it very difficult for Drow Ranger to keep her distance from Slark, thereby losing her Marksmanship bonus.
* Gust is rarely enough to keep Slark at bay, as Drow Ranger has no movement abilities and will simply be chased down afterwards.
* Drow Ranger's heavy dependence on agility also makes her significantly weaker after being drained by Essence Shift.

* Pounce can easily break Static Link, making it less powerful against him.
* Slark is one of the few heroes who can man fight a Razor, because of Essence Shift.
* Shadow Dance can prevent Razor from killing him and may provide an opportunity to kill Razor due to it preventing Razor from attacking Slark.

* Ice Blast prevents Insatiable Hunger lifesteal, Spin Web regeneration and quickly kills spiderlings.

* Heroes that withstand damage like Timbersaw, Bristleback, Dragon Knight and others will have their durability largely reduced when hit by an Ice Blast due to the risk of shattering.

* Pounce also stops Nature's Prophet's Teleportation.

* Heroes that can jump on her: Slark, Queen of Pain, Anti-Mage

* Lycan cannot escape from a Pounce even if he uses Shapeshift, and has no disabling abilities to stop Slark.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Heroes like Slark, Witch Doctor and others also tend to suffer in Ice Blast's heal denial.

* Heroes with global abilities can give Legion Commander's opponent an edge in Duels from anywhere on the map: Nature's Prophet, Ancient Apparition, Zeus, Invoker, Treant Protector

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Heroes with strong dispels can remove Primal Roar's stun: Abaddon, Slark, Oracle.

* Heroes who have a high mobility (Queen of Pain, Storm Spirit, Slark, etc.).

* Ancient Apparition's Cold Feet will freeze Clockwerk in place if he stays inside his Power Cogs. His immobility while in his cogs also makes him a very easy target to Ice Vortex and Ice Blast.

* Enigma is fragile, and lacks escapes, being dependent on Blink Dagger for mobility. Ganking Heroes or Heroes with burst damage will likely kill him before he can do anything. Such Heroes include: Lina, Lion, Puck, Slark, Nyx Assassin, etc.

* Ice Blast negates healing from Shadow Wave, and lasts longer than Shallow Grave.
Additional:
* Shallow Grave prevents Ice Blast's shatter for up to 5 seconds, but can mostly only delay it as Ice Blast's debuff lasts 10 seconds and prevents Shadow Wave from healing them.

* Slark's Pounce allows him to close the gap on Phantom Assassin and prevent her from escaping with Phantom Strike.
* As a hero who always goes for the Silver Edge and Abyssal Blade Slark can use it to disable Phantom Assassin and her Blur and Coup de Grace, drastically reducing her damage output and ability to evade attacks, and also preventing her from acting.
* Phantom Assassin's Coup de Grace requires Random Number Generation in order to proc, which gives Slark more than enough time to escape and recover himself.

* Cold Feet's debuff affects Death Prophet even while she's affected by Eul's Scepter of Divinity.
* Ice Vortex lowers her magic resistance and her kiting potential.
* Ice Blast prevents Death Prophet from gaining health from Spirit Siphon and Exorcism.
Additional:
* Ice Blast prevents Death Prophet from gaining health from Spirit Siphon and Exorcism.

* Dark Pact can dispel Flaming Lasso if is used in anticipation, but a Blink initiation from fog can catch the Slark off guard.
* Slark can also take off any Sticky Napalm stacks with Dark Pact in lane.

* Shadow Dance prevents Luna from damaging Slark, and together with Shadow Blade he can kite her or escape.
* Luna has no way to escape from Pounce's leash.
Additional:
* Luna's lack of mobility and escape abilities makes her easily gankable by Slark.
* Shadow Dance will avoid all the damage from Eclipse.
* For the same reasons, Slark is a good ally for Luna when they are in the same team.

* Chilling Touch's damage component can easily overwhelm Aphotic Shield's damage block.
* Ice Blast's nullifies Abaddon healing from Borrowed Time and Mist Coil and it is not dispelled by Aphotic Shield.
Additional:
* Ice Blast nullifies Borrowed Time's and Mist Coil's healing.

* Dark Pact can dispel Enfeeble, as well as Nightmare and Fiend's Grip if timed well.
* Shadow Dance protects Slark from Bane's single-target-only abilities.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Heroes that withstand damage like Timbersaw, Bristleback, Dragon Knight and others will have their durability largely reduced when hit by an Ice Blast due to the risk of shattering.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Since all of Phoenix's abilities (except for Supernova) have health costs, heroes like Ancient Apparition or Necrophos can turn Phoenix's abilities against it. However, Supernova does completely protect Phoenix from Ice Blast.

* Heroes with dispels: Legion Commander, Oracle, Slark

* Heroes who can dispel will be able to remove Shadow Poison before Shadow Demon can build up a big stack, or remove Soul Catcher's debuff to instantly bring the health of affected heroes back to a considerable amount: Abaddon, Slark, Legion Commander, Oracle.

* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

Additional:
* Dark Pact rips through Refraction charges and still steals attributes during Refraction.
* Pounce and Dark Pact will still hit Templar Assassin while she is Melded. Since she cannot move, both abilities will be easy for Slark to land.

* Heroes with invisibility and high mobility can jump on and focus down Earthshaker before he has a chance to initiate: Clinkz, Slark, Storm Spirit

* Dark Seer relies on Surge for most of his mobility, so he's not very vulnerable to slows, but much more to root effects and walls or pseudo-walls such as Disruptor's Kinetic Field or Slark's Pounce.

* Nyx Assassin, Bounty Hunter and Slark can all sneak up and kill you, Nyx being particularly deadly. Watch Slark carefully, as he can break either (but not both unless you are making a mistake) of your disables, with Dark Pact and leap out of a serpent ward ring. These heroes, however, rely heavily on escape and are themselves not very durable and none of them can survive a full lockdown with Mass Serpent Ward. Having Sentry Wards can turn you from prey to predator.

* Slark with Dark Pact
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Heroes with escaping and disjointing abilities can be good against Juggernaut: Riki, Queen of Pain, Puck, Storm Spirit, Ember Spirit, Slark etc.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* If Slark sees the Sacred Arrow before it hits him, he can use Dark Pact to remove it a moment later.
* Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's Aghanim's Scepter​ combo with Shadow Dance.

* Zeus can deal a huge amount of damage, but he lacks defensive abilities, such as good mobility or resistance. Due to that, he doesn't like to be touched by any means. Heroes with higher damage output and good mobility will often get easily near Zeus and trade damage (eventually causing Zeus's downfall). Such Heroes include: Lycan, Slark, Storm Spirit, Spectre and others.