Jakiro
[wiki] rating: 2.0 (winrate: 50% pickrate: 11%)Doom
[wiki] rating: 2.0 (winrate: 47% pickrate: 6%)Nature's Prophet
* Doom can eats Nature's Prophet's treants with 
Devour and gains lots of gold.
* Doom can buy 
Radiance or use his 
Scorched Earth to quickly wipe out a swarm of Treants.
* 
Doom and a ministun from 
Infernal Blade's prevents Nature's Prophet from escaping with Sprout and Teleportation.
Axe
* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Axe more than most normal attacks, negating some of his durability.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Axe.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom's naturally low attack speed makes Counter Helix less likely to proc, and his high base health allows him to take a few Helixes with no danger.
* Doom makes Axe less disruptive, preventing him from using his skills or items. With 
Aghanim's Scepter, Counter Helix is also disabled, making him effectively useless for a lengthy duration.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Axe.
* Doom has low attack speed because of his high Base-Attack-Time, poor agility gain and limited attack-speed granting items which are commonly built. This means Doom will trigger 
Counter Helix less often and thus is an unideal target for initiation.
* Doom has naturally high HP so it takes longer for Doom to be brought down to the killing threshold of 
Culling Blade.
* Axe is highly reliant on his abilities and items to be effective during a fight. Without the usage of 
Berserker's Call and 
Blink Dagger due to Doom, Axe offers very little in the way of damage, effectively removing him from a fight.
Clockwerk
[wiki] rating: 1.6 (winrate: 49% pickrate: 6%)Axe
* Heroes who can slow and kite Axe will severely inhibit his presence in fights: 
Bristleback, 
Crystal Maiden, 
Batrider, 
Arc Warden, 
Winter Wyvern, 
Clockwerk
Nature's Prophet
* Clockwerk's long range initiation and catch makes it incredibly difficult for Nature's Prophet to split push and show on the map alone.
* 
Rocket Flare can be used to scout Nature's Prophet if he is hiding in the forest, and can provide vision inside of Sprout.
Batrider
[wiki] rating: 1.6 (winrate: 46% pickrate: 2%)Nature's Prophet
* 
Firefly can be used to clear Nature's Prophet's Treants and allows Batrider destroy Sprout's trees.
* 
Flaming Lasso prevents Nature's Prophet from escaping using Teleportation.
Axe
* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk
Timbersaw
[wiki] rating: 1.6 (winrate: 45% pickrate: 4%)Axe
* Special mention to 
Timbersaw as he has a way to deal with Axe in the laning stage, but still needs to be careful about Berserker's Call stun, the pure damage from Counter Helix and Culling Blade finishing him off before he can escape or heal from his passive.
Additional:
* 
Whirling Death reduces Axe's strength by 15%, which makes him less durable, especially from early game. It's also stackable.
* 
Blade Mail are not effective against attribute changes, and 
Timber Chain can wait out Blade Mail's duration to wear off.
* 
Reactive Armor makes it harder for Axe to finish off Timbersaw with Culling Blade.
* 
Chakram disarms Timbersaw, which makes Axe's Counter Helix useless against him.
* All Timbersaw skills deal pure damage, which bypass Axe's high armor or bonus armor from Berserker's Call.
Nature's Prophet
* All three of Timbersaw’s abilities give him an easy way out of Sprout, and can also destroy nearby trees so Nature's Prophet can’t spawn Treants.
* If Prophet tries to escape with a self Sprout/Teleport, Timbersaw can easily cut down all its trees to get to him and deal increased Whirling Death damage as well.
* Chakram heavily discourages teleports.
* Timbersaw is quite well suited to clearing massive waves of Treants almost instantly with all of his area of effect pure damage abilities, preventing Nature's Prophet from pushing.
* Treants can give Reactive Armor many charges quite quickly.
Additional:
* Timbersaw can easily cut down trees from 
Sprout, making it very difficult for Nature's Prophet to teleport away or trap enemies.
* Timbersaw's abilities quickly clear out treants.
* Reactive Armor negates most of the damage of Nature's Prophet's treants, and Timbersaw can often allow himself to be attacked in order to heal himself.
Winter Wyvern
[wiki] rating: 1.2 (winrate: 49% pickrate: 6%)Nature's Prophet
* 
Broodmother, 
Nature's Prophet, 
Phantom Lancer by their nature offer very good target for Splinter Blast and Winter's Curse.
Axe
* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk
Omniknight
[wiki] rating: 1.0 (winrate: 55% pickrate: 4%)Axe
* Omniknight's healing prevents allies from dropping low enough for Culling Blade
* 
Heavenly Grace dispels 
Battle Hunger.
* Axe also tends to get close to allied heroes in order to damage them with his Counter Helix, which can easily be punished by Purification.
Tinker
[wiki] rating: 1.0 (winrate: 54% pickrate: 9%)Nature's Prophet
* Tinker has great map presence because of 
Keen Conveyance and 
Rearm, which means he can always teleport and defend towers whenever Nature's Prophet tries to push.
* 
Laser prevents Nature's Prophet from attacking. Additionally, even with 
Monkey King Bar, Nature's Prophet cannot hit towers and buildings during the effect.
Lone Druid
[wiki] rating: 1.0 (winrate: 53% pickrate: 3%)Nature's Prophet
* Once caught in Bear's Entangle, Nature's Prophet cannot escape with 
Teleportation.
Ursa
[wiki] rating: 1.0 (winrate: 52% pickrate: 11%)Axe
* 
Enrage reduces the damage from Blade Mail and Counter Helix to a minimum, forcing Axe to play around Ursa's ultimate ability.
* 
Overpower and 
Fury Swipes stacks damage overwhelming for Axe, despite his high health.
Undying
[wiki] rating: 1.0 (winrate: 52% pickrate: 11%)Nature's Prophet
* Undying's 
Tombstone will cheerfully chew through treants, incidentally netting you some extra income during fights.
* The above interaction tends to ensure that skirmishes are heavily populated with units, thereby buffing 
Soul Rip
Earthshaker
[wiki] rating: 1.0 (winrate: 51% pickrate: 12%)Nature's Prophet
* Treants increase Echo Slam's damage.
* Earthshaker's AoE stuns can hit Nature's Prophet through Sprout, without having direct line of sight, in order to interrupt Teleportation.
Additional:
* 
Echo Slam can do a lot of damage to Nature's Prophet and his teammates if they stand close to his Treants.
Night Stalker
[wiki] rating: 1.0 (winrate: 50% pickrate: 6%)Axe
* 
Crippling Fear makes it so Axe might use Blink Dagger right into an AoE silence in the middle of everyone.
* 
Void cripples Axe's already bad movement speed and attack speed.
* 
Hunter in the Night makes it impossible for Axe to catch up to a fleeing or escape from Night Stalker during the night.
* Lastly, 
Dark Ascension gives full vision over Axe before he initiates, making the opponents all recognise his location immediately and allowing Night Stalker to prevent it or vocally tell his team if needed.
* Night Stalker has very high strength gain, even in lane, so a successful Culling Blade is very unlikely.
* Axe's Blade Mail will likely do nothing to Night Stalker because of his high health and certain requirements for him to do the most damage to be true.
Underlord
[wiki] rating: 1.0 (winrate: 50% pickrate: 3%)Nature's Prophet
* 
Firestorm makes quick work of Treants and 
Atrophy Aura gives him temporary damage for every Treant killed.
* 
Pit of Malice can stop Teleportation channeling.
* Atrophy Aura greatly reduces Nature's Prophet's damage and he has no other good way to deal damage.
* 
Fiend's Gate can counter split-pushing, which is something that Nature's Prophet relies on a lot.
Elder Titan
[wiki] rating: 1.0 (winrate: 50% pickrate: 2%)Nature's Prophet
* 
Astral Spirit can give Elder Titan a lot of damage and movement speed if Nature's Prophet sends all of his Treants together.
* Not only does 
Echo Stomp prevent Nature's Prophet from escaping using Teleportation, but Astral Spirit can be used to bypass Sprout and cancel Teleportation with it's own Echo Stomp from long distances.
* 
Earth Splitter can clear Nature's Prophet's Treants effectively.
Dawnbreaker
[wiki] rating: 1.0 (winrate: 50% pickrate: 11%)Nature's Prophet
* Starbreaker and Celestial Hammer does high AoE damage which easily clears {U:Treant}, shutting down most of Nature's Prophets damage and pushing power.
* Dawnbreaker can teleport to deal with split-pushing Nature's Prophet and rejoin her team with Solar Guardian when they require it.
* Since Starbreaker clears trees in its path followed by a stun at the end Nature's Prophet will be unable to escape the dangerous situation by using Sprout on himself and teleporting away with either Teleportation or 
Town Portal Scroll.
Additional:
* Starbreaker and Celestial Hammer does high AoE damage which easily clears {U:Treant}, shutting down most of Nature's Prophets damage and pushing power.
* Dawnbreaker can teleport to deal with split-pushing Nature's Prophet and rejoin her team with Solar Guardian when they require it.
* Since Starbreaker clears trees in its path followed by a stun at the end Nature's Prophet will be unable to escape the dangerous situation by using Sprout on himself and teleporting away with either Teleportation or Town Portal Scroll.
Outworld Destroyer
[wiki] rating: 1.0 (winrate: 50% pickrate: 9%)Axe
* Outworld Destroyer's pure and magical damage is particularly effective against Axe.
* 
Astral Imprisonment is an excellent way to defend against an initiating Axe.
* 
Sanity's Eclipse deals high damage to Axe due to his low mana pool.
Additional:
* Berserker's Call bonus armor doesn't block Arcane Orb's pure damage.
* Astral Imprisonment can be used to prevent an ally or Outworld Destroyer himself from an Axe initiation.
* Axe's low mana means he's susceptible to a powerful Sanity's Eclipse.
Spectre
[wiki] rating: 1.0 (winrate: 49% pickrate: 5%)Nature's Prophet
* 
Shadow Step's low cooldown allows Spectre to teleport to him whenever he decides to push.
* 
Spectral Dagger allows Spectre to go through Sprout's trees and stun Nature's Prophet if she has a 
Skull Basher or 
Abyssal Blade.
* Spectre loves buying Radiance, which can kill Nature's Prophet's Treants easily.
Additional:
* Spectre can get to him anywhere on the map with 
Haunt.
* Spectre can pass through his trees with Spectral Dagger.
* 
Desolate's damage will melt him quickly, as he's alone most of the time.
Phoenix
[wiki] rating: 1.0 (winrate: 49% pickrate: 5%)Axe
* 
Sun Ray allows Phoenix to heal any allies caught in Berserker's Call, while burning away Axe's high HP at the same time.
* 
Icarus Dive and 
Fire Spirits puts Axe's Blink Dagger on cooldown.
* Axe's slow attack speed makes it difficult for him to destroy 
Supernova on his own.
Sand King
[wiki] rating: 1.0 (winrate: 49% pickrate: 5%)Nature's Prophet
* With Caustic Finale, Sand King can easily kill the treants from 
Nature's Call.
* Burrowstrike allows Sand King to prevent Nature's Prophet from using Teleportation inside of his Sprout.
Additional:
* Sand King's 
Caustic Finale combined with 
Sand Storm will kill Treants easily.
* Sand King can interrupt Teleportation with 
Burrowstrike, even through Sprout.
Ember Spirit
[wiki] rating: 1.0 (winrate: 48% pickrate: 8%)Nature's Prophet
* 
Sleight of Fist with 
Battle Fury deals a lot of damage to Nature's Prophet's team if they stand close to his Treants, as well as killing all the Treants with ease.
* Ember Spirit with 
Fire Remnant and 
Boots of Travel can be very active around the map, which enables him to quickly teleport and defend the objective Nature's Prophet is attacking whenever he tries to push.
Additional:
* Ember Spirit can easily deal with Nature's Call by using his Flame Guard and with Battle Fury. He also has multiple ways of escaping Sprout. Additionally, Ember Spirit can break Sprout's trees with Activate Fire Remnant and interrupt Teleportation with Searing Chains.
Ogre Magi
[wiki] rating: 1.0 (winrate: 47% pickrate: 11%)Nature's Prophet
* Nature's Prophet treants can be cleared by Ignite or Multicast 
Hand of Midas
* Fireblast and Unrefined Fireblast prevents Nature's Prophet from using Teleportation.
Death Prophet
[wiki] rating: 1.0 (winrate: 47% pickrate: 3%)Nature's Prophet
* Crypt Swarm can quickly kill any Treants. Silence also prevents him from using Teleportation to escape or Sprout to lock you down.
Additional:
* 
Crypt Swarm helps clear waves of Treants.
* 
Silence prevents Nature's Prophet from using Sprout or Teleportation.
* 
Exorcism kills Treants with ease.
Storm Spirit
[wiki] rating: 1.0 (winrate: 47% pickrate: 4%)Nature's Prophet
* 
Ball Lightning can be used to clear Nature's Prophet's Treants and easily destroys Sprout.
* 
Electric Vortex prevents Nature's Prophet's escaping using Teleportation.
Medusa
[wiki] rating: 1.0 (winrate: 47% pickrate: 2%)Axe
* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to pursue.
Necrophos
[wiki] rating: 1.0 (winrate: 46% pickrate: 6%)Axe
* Frequent healing from 
Death Pulse and 
Mekansm makes it difficult for Axe to finish off targets with Culling Blade.
* 
Ghost Shroud's instant cast time allows Necrophos to turn ethereal before being initiated on by Berserker's Call. This prevents him from attacking Axe while taunted, thus lowering the chance to proc Counter Helix.
* Axe's high health is relatively ineffective against 
Heartstopper Aura's percentage-based health degeneration.
* 
Reaper's Scythe stops Axe's game plan of using Berserker's Call multiple times and since he's in the middle of the fight, this spell is very easy to grab kills onto him.
Additional:
* Frequent healing from Death Pulse makes it difficult for Axe to finish off targets with Culling Blade.
* Reaper's Scythe negates Axe's tankiness, and can kill him quickly after initiation if Axe's health is low enough.
* Heartstopper Aura can be very effective against Axe due to Axe's high strength gain.
* However, bear in mind that Berserker's Call can prevent Necrophos from using his Ghost Shroud to defend his fragile self from physical damages. And Heartstopper Aura can unintentionally help Axe to trigger his Counter Helix more frequently while also hurting Necrophos with Blade Mail during activation.
* Nonetheless Heartstopper Aura is not considered as a normal attack, thus it will not trigger Counter Helix, so anyone who wrote the statement above should be awarded with MVP and considered a TI champion purely for the innovation of new mechanics.
Shadow Demon
[wiki] rating: 1.0 (winrate: 46% pickrate: 2%)Axe
* 
Disruption will save Shadow Demon's teammates from being killed by Counter Helix or Culling Blade.
* 
Demonic Purge slows Axe to a crawl, making him nearly useless after initiating. If Shadow Demon has Aghanim's Scepter, it will also break Counter Helix.
Pugna
[wiki] rating: 1.0 (winrate: 46% pickrate: 2%)Axe
* 
Decrepify can be used on allies to prevent them from attacking Axe and triggering Counter Helix during Berserker's Call. He can also cast it on Axe to prevent anyone from attacking him.
* 
Life Drain can be used to heal himself or allies caught in Berserker's Call, preventing them from dropping low enough for Axe to kill them with Culling Blade.
Tidehunter
[wiki] rating: 0.6 (winrate: 54% pickrate: 9%)Nature's Prophet
* Most summons and illusions can barely hurt Tidehunter at all, after their attacks get reduced by Anchor Smash and blocked by Kraken Shell: Nature's Prophet, 
Enigma
* Also Ravage's large area of effect and damage can easily damage all those units at once, or just straight up clear them.
Brewmaster
[wiki] rating: 0.6 (winrate: 53% pickrate: 2%)Nature's Prophet
* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: Broodmother, Enigma, Nature's Prophet.
Enigma
[wiki] rating: 0.6 (winrate: 52% pickrate: 6%)Axe
* Enigma can be a perfect counter-initiator with his ultimate. A perfectly timed Black Hole will turn the tide of any initiation, especially from heroes like; 
Spirit Breaker, 
Legion Commander, 
Axe, 
Puck, and 
Slardar
Leshrac
[wiki] rating: 0.6 (winrate: 52% pickrate: 10%)Nature's Prophet
* Heroes who summon multiple units that are not spell immune. Nature's Prophet,
Lycan,
Beastmaster
Clinkz
[wiki] rating: 0.6 (winrate: 52% pickrate: 9%)Nature's Prophet
* Heroes with invisibility: (
Riki, 
Clinkz, 
Nyx Assassin
Additional:
* Nature's Prophet is often by himself. Clinkz can use invisibility to hunt him down and kill him, although a Quelling Blade may be needed to cut through his Sprout. Orchid Malevolence may also be needed if 3-4 seconds are not enough time to kill him, as he can teleport away.
* Clinkz can match Nature's Prophet's ability to split push.
Nyx Assassin
[wiki] rating: 0.6 (winrate: 52% pickrate: 7%)Nature's Prophet
* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin
Crystal Maiden
[wiki] rating: 0.6 (winrate: 51% pickrate: 18%)Axe
* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk
Chen
[wiki] rating: 0.6 (winrate: 50% pickrate: 1%)Axe
* Hand of God and Divine Favor make it hard for Axe to finish off allies with Culling Blade.
Magnus
[wiki] rating: 0.6 (winrate: 50% pickrate: 11%)Nature's Prophet
* Heroes with cleave damage: 
Sven, 
Magnus, 
Kunkka
Gyrocopter
[wiki] rating: 0.6 (winrate: 49% pickrate: 7%)Axe
* Heroes that relies on armor or other type of physical damage negation are easy for Gyrocopter to take down during the early game with his magical damage: Axe, 
Dragon Knight, Sven.
Puck
[wiki] rating: 0.6 (winrate: 47% pickrate: 7%)Nature's Prophet
* Mass summoning heroes: Broodmother, Nature's Prophet and Enigma all have summons Puck can clear clear with Illusory Orb and Waning Rift instantly, due to their summons having low health.
Kunkka
[wiki] rating: 0.6 (winrate: 46% pickrate: 4%)Nature's Prophet
* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as 
Tinker and Nature's Prophet.
* In general, highly mobile heroes like 
Earth Spirit or 
Storm Spirit are at a disadvantage against X Marks the Spot.
* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.
Lion
[wiki] rating: 0.6 (winrate: 46% pickrate: 12%)Axe
* Ranged heroes that can easily harass Axe: 
Drow Ranger, 
Sniper, 
Lion.
Keeper of the Light
[wiki] rating: 0.6 (winrate: 46% pickrate: 3%)Nature's Prophet
* Heroes that have AoE damage: 
Lina, 
Keeper of the Light, Timbersaw, 
Leshrac, Bristleback, Axe
Bristleback
[wiki] rating: 0.6 (winrate: 42% pickrate: 2%)Nature's Prophet
* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe
Axe
* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk
Axe
* Axe forces Bristleback to turn around with Berserker's Call, allowing allies to attack him without fear of his passive.
Meepo
[wiki] rating: 0.4 (winrate: 52% pickrate: 1%)Nature's Prophet
* Meepo can net Nature's Prophet's treants with 
Earthbind and then 
Poof them, putting an end to his pushing.
* Skilled 
Meepos can rival and even exceed Nature's Prophet's global presence by combining Poof with Boots of Travel, meaning that he can not only stop his push, but also can kill him if he is not careful.
Axe
* Melee heroes who rely on summons, illusions or clones will trigger Counter Helix more often, thus taking more damage: Meepo, Lycan, Phantom Lancer
Additional:
* The combination of Counter Helix and Berserker's Call can disable multiple Meepos and deal heavy area damage.
* Axe's natural high survivability makes it difficult to burst him down with Poof or chip away at his health with Ransack.
Shadow Shaman
[wiki] rating: 0.4 (winrate: 50% pickrate: 8%)Nature's Prophet
* Mass Serpent Ward can kill lots of treants if played defensively.
* Mass Serpent Ward, Hex and Shackles can catch and kill a Nature's Prophet trying to use Teleportation.
Additional:
* Shadow Shaman's 
Mass Serpent Ward together with 
Ether Shock can easily kill lots of Treants if played defensively.
* 
Hex and 
Shackles can disrupt Nature's Prophet's escape attempts with Teleportation.
Axe
* 
Pudge, Legion Commander and Axe will make the match a living hell for you, since they are known for surprise attacks from the fog and quickly killing low HP heroes. They can also interrupt your channeling, Legion being especially problematic, as she can use 
Press the Attack on an ally who is hexed as well.
Venomancer
[wiki] rating: 0.4 (winrate: 50% pickrate: 6%)Axe
* Venomancer's slows and magical damage-over-time work well against Axe's complete lack of mobility.
* 
Plague Ward is especially useful for slowing down Axe, and revealing him before he initiates, as well as putting his Blink Dagger on cooldown.
Additional:
* Venomancer's slows and magical damage-over-time work well against Axe's complete lack of mobility.
* Plague Wards is especially useful for slowing down Axe, and revealing him before he initiates, as well as putting his Blink Dagger on cooldown.
* For the same reasons, Venomancer is a good ally for Axe when the situation is reversed.
Nature's Prophet
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, 
Chen, Clinkz, Drow Ranger, Lina, 
Mirana, Nature's Prophet, 
Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Additional:
* Teleportation allows Natures Prophet to save himself from the damage over time of 
Venomous Gale, 
Poison Sting and 
Poison Nova.
* Plague Wards can be destroyed with Nature's Prophet's Treants.
Lifestealer
[wiki] rating: 0.4 (winrate: 50% pickrate: 9%)Axe
* Feast makes it impossible to put Lifestealer's health for a Culling Blade and also deals high damage to Axe due to his naturally high health.
* However, Lifestealer's Rage can be pierced by Berserker's Call, Counter Helix and Culling Blade.
Nature's Prophet
* Sprout is good for trapping melee carries with no escape abilities: Sven, 
Alchemist, 
Lifestealer etc.
Spirit Breaker
[wiki] rating: 0.4 (winrate: 49% pickrate: 9%)Nature's Prophet
* Spirit Breaker can chase Nature's Prophet from anywhere on the map with 
Charge of Darkness, making it hard for Nature's Prophet to split-push.
Additional:
* Charge of Darkness allows Spirit Breaker to catch Nature's Prophet out when he tries to split push.
* Nature's Prophet can't hide in his Sprout against Spirit Breaker, as his Charge of Darkness provides vision on its target.
* Spirit Breaker can easily cancel Nature's Prophet's Teleportation.
Axe
* Heroes who continue dealing damage while being stunned: 
Luna, 
Razor, Axe, Bristleback, Leshrac,
Viper
[wiki] rating: 0.4 (winrate: 47% pickrate: 4%)Axe
* 
Poison Attack and 
Viper Strike slows Axe significantly, and puts his Blink Dagger on cooldown, preventing him from initiating.
* 
Nethertoxin can break Counter Helix.
Additional:
* Nethertoxin prevents Counter Helix from triggering, which significantly lowers Axe's damage output in the early to mid game.
* Viper's various slows and damage over time prevents Axe from initiating as well as putting his Blink Dagger on cooldown.
Nature's Prophet
* Heroes who do not have nor rely on passive abilities make Nethertoxin much less effective: Clinkz, Pugna, Nature's Prophet, 
Dark Seer, Lycan, 
Tusk
Weaver
[wiki] rating: -2.0 (winrate: 49% pickrate: 4%)Nature's Prophet
* Sprout with True Sight items (
Sentry Ward or 
Dust of Appearance) make it possible to trap Weaver in lane, unless he buys 
Quelling Blade or until he unlocks 
Time Lapse.
* 
The Swarm beetles can be destroyed with Nature's Prophet's Treants.
Axe
* Berserker's Call is one of the best ways to lock down Weaver before he has a chance to use Time Lapse. It can also catch Weaver in 
Shukuchi.
* Weaver's high attack speed, along with high attack damage from 
Geminate Attack, triggers Counter Helix continuously and the output damage would be returned by Blade Mail.
Additional:
* Berserker's Call is one of the best ways to lock down Weaver before he has a chance to use Time Lapse. It can also catch Weaver in Shukuchi.
* Due to his fast attack speed from Geminate Attack and items that give attack speed, Counter Helix will activate a lot, and the damage would be returned by Blade Mail, which hurts Weaver far more than it hurts Axe.
* Culling Blade can finish off Weaver's low health pool before he escapes with Shukuchi and Time Lapse.
* Battle Hunger is a good tool to pop Weaver's 
Linken's Sphere due to its low cooldown.
Terrorblade
[wiki] rating: -1.6 (winrate: 46% pickrate: 4%)Axe
* Terrorblade's low base health and lack of mobility make him an easy target for Axe to initiate on, and kill.
* Counter Helix will trigger from, and destroy many of Terrorblade illusions.
Additional:
* Berserker's Call and Counter Helix together can be devastating to Terrorblade, especially if Terrorblade has a lot of illusions. Their high attack speed will trigger Counter Helix a lot, and the pure damage will quickly slice through Terrorblade's low health and kill his illusions. More importantly, the Berserker's Call can pierce through spell immunity from 
Black King Bar, Terrorblade's only survival item besides 
Manta Style which cannot be used to dispel Berserker's Call. With enough burst damage by Axe's teammates, Terrorblade can be finished off even before taunt duration runs out and he gets a chance to save himself with 
Sunder.
* Culling Blade can finish off Terrorblade before he has the chance to Sunder due to his low health in the early to mid game. And every time Terrorblade or any of his allies are successfully killed by Culling Blade, Axe permanently gains armor from it, which in combination with armor items that Axe often purchases like Blade Mail, 
Crimson Guard, 
Assault Cuirass and 
Shiva's Guard can make Terrorblade's attacks only tickle Axe, even during Metamorphosis.
* Terrorblade's low base health and lack of mobility make him an easy target for Axe to initiate on, and kill.
Nature's Prophet
* Heroes who can summon illusions and summons because Terrorblade has no abilities to deal with multiple enemies at once outside Reflection: 
Shadow Shaman, 
Naga Siren, Broodmother, Lycan, Enigma, 
Chaos Knight, Phantom Lancer, 
Shadow Demon, Dark Seer, Nature's Prophet, 
Invoker, 
Morphling, 
Grimstroke with Aghanim's Scepter.
Juggernaut
[wiki] rating: -1.6 (winrate: 50% pickrate: 17%)Nature's Prophet
* Nature's Call can be used to tank 
Omnislash in the early to mid game due to their high health pool combined.
* Sprout can trap Juggernaut, even if he is using 
Blade Fury. Aghanim's Shard upgraded Sprout can also prevent Juggernaut from escaping if he buys 
Battlefury.
* Once Nature's prophet reach lv 20 with leash talent on Sprout, he can stop Juggernaut from escaping with Blade Fury and TPing away.
* Nature's Prophet can farm and push much faster than Juggernaut, acquiring map control before he can do much.
Axe
* Heroes who rely on fast attack speed will also trigger Counter Helix frequently: 
Faceless Void, 
Troll Warlord, 
Anti-Mage, 
Juggernaut, Arc Warden, Morphling
Additional:
* Berserker's Call pierces spell immunity, making a Blade Fury teleport escape impossible. It's very useful against Omnislash as well.
* Juggernaut's low base health and high attack speed causes him to take a lot of damage from Counter Helix.
* Axe is a common Blade Mail and Blink Dagger carrier making him a very big potential threat before Juggernaut get his items.
Alchemist
[wiki] rating: -1.0 (winrate: 46% pickrate: 3%)Nature's Prophet
* Alchemist gets a huge amount of additional gold from killing Nature's Prophet's treants thanks to 
Greevil's Greed
Additional:
* Acid Spray and Greevil's Greed will quickly destroy pushes with treants.
Axe
* Axe can force Alchemist to attack him with Berserker's Call. High attack speed from 
Chemical Rage will cause Counter Helix to proc multiple times.
* This can get worse if axe has Blade Mail, which then returns all damage to Alchemist himself.
* Axe's abilities can pierce through Black King Bar, which is a common item for Alchemist.
* Berserker's Call grants Axe a huge bonus armor, which greatly counters Alchemist's physical damage for the most part.
Nature's Prophet
* Sprout is good for trapping melee carries with no escape abilities: Sven, Alchemist, Lifestealer etc.
Morphling
[wiki] rating: -1.0 (winrate: 47% pickrate: 11%)Axe
* Jumping on Axe with 
Waveform will make Morphling an easy target for a counter-initiation with Berserker's Call.
* Morphling is often played at low health to maximise the bonuses from 
Attribute Shift (Agility Gain), and also because his abilities cost health to use. This makes him especially vulnerable to Culling Blade.
* However, Morphling is common Linken's Sphere carrier to block Culling Blade forces Axe to use Battle Hunger to pop the Spell Block first.
* Attribute Shift (Agility Gain) gives Morphlig no protection against the pure damage of Culling Blade. Its attack speed bonus also means that Counter Helix will proc more often.
Dark Willow
[wiki] rating: -1.0 (winrate: 47% pickrate: 5%)Axe
* Berserker's Call forces Dark Willow to attack, cancelling Shadow Realm.
Windranger
[wiki] rating: -1.0 (winrate: 48% pickrate: 9%)Axe
* Windrun does not provide protection against Counter Helix and Berserker's Call. Her fast attack speed with Focus Fire will also quickly trigger Counter Helix multiple times.
Troll Warlord
[wiki] rating: -1.0 (winrate: 49% pickrate: 2%)Axe
* Troll Warlord's high attack speed means Counter Helix will proc extremely frequently even without creeps near him. This, combined with a Blade Mail means Axe can easily solo kill Troll Warlord even in later stages of the game.
* 
Battle Trance does not save Troll Warlord from a Culling Blade.
Additional:
* Troll Warlord has significant attack speed due to Fervor and Battle Trance, giving Axe a higher chance to proc Counter Helix and seriously injure Troll Warlord due to his relatively low maximum health.
* Axe often purchases Blade Mail, which can help Axe turn Troll Warlord's farm and high physical damage against him. The bonus armor provided by Berserker's Call means that Troll Warlord will take a lot more damage than Axe.
* Culling Blade is still capable of killing Troll Warlord during Battle Trance if his HP is low enough.
Sniper
[wiki] rating: -1.0 (winrate: 50% pickrate: 17%)Axe
* Ranged heroes that can easily harass Axe: Drow Ranger, Sniper, Lion.
Axe
* Axe can easily close the distance to Sniper with Blink Dagger.
* With Berserker's Call in combination with Counter Helix and Battle Hunger, Axe can make short work of Sniper, finishing him off easily with Culling Blade due to his low HP & high attack speed in the late game.
Nature's Prophet
* Heroes with high mobility can approach Sniper: Anti-Mage, Earth Spirit, 
Io, Nature's Prophet, 
Pangolier, Puck, 
Queen of Pain and most notably Riki.
Dazzle
[wiki] rating: -1.0 (winrate: 50% pickrate: 7%)Axe
* Culling Blade ignores the protection from 
Shallow Grave, and will kill any target whose health is low enough. This makes Axe one of the hardest counters to Dazzle, and he neutralizes one of Dazzle's most important abilities.
Additional:
* Culling Blade kills any target under the health threshold, even through Shallow Grave.
Oracle
[wiki] rating: -1.0 (winrate: 50% pickrate: 4%)Axe
* False Promise will not save an ally from Culling Blade if their health is low enough.
* Fate's Edict, offensively or defensively, does little to protect Oracle's allies from the majority of Axe's damage.
Legion Commander
[wiki] rating: -1.0 (winrate: 51% pickrate: 13%)Nature's Prophet
* Legion Commander's 
Overwhelming Odds deals damage for every Treant it hits, which allows it to easily wipe out large waves of them.
Nature's Prophet
* Heroes with global abilities can give Legion Commander's opponent an edge in Duels from anywhere on the map: Nature's Prophet, 
Ancient Apparition, 
Zeus, Invoker, 
Treant Protector
Axe
* Axe usually wants to fight in the middle of creep waves to proc his Counter Helix. Legion Commander wants to do the same thing to proc Moment of Courage, often resulting in Axe getting a huge amount of damage in against Legion Commander.
* Axe's high armor gain thanks to Culling Blade makes him almost impossible to kill during a Duel in the late game.
Phantom Lancer
[wiki] rating: -1.0 (winrate: 51% pickrate: 4%)Axe
* Berserker's Call catches Phantom Lancer when he is hidden among his illusions.
* Counter Helix quickly destroys Phantom Lancer's illusion army. The more illusions there are, the more often Counter Helix is triggered.
* Phantom Lancer's low early game health makes him an easy target for Culling Blade.
Additional:
* Berserker's Call helps locking down Phantom Lancer in a group of illusions.
* Counter Helix combined with Blade Mail clears Phantom Lancer's illusions quickly.
* Phantom Lancer's low health in the early game makes him a frequent target for Culling Blade.
Treant Protector
[wiki] rating: -1.0 (winrate: 51% pickrate: 3%)Nature's Prophet
* Nature's Prophet's Nature's Call can destroy trees that Treant Protecter is hiding in, revealing him.
Abaddon
[wiki] rating: -1.0 (winrate: 51% pickrate: 3%)Axe
* Culling Blade ignores 
Borrowed Time should Abaddon's health falls under the threshold.
* 
Aphotic Shield does nothing against Berserkers Call and has to be used constantly to remove the very small mana cost of Battle Hunger in lane.
Additional:
* Culling Blade's instant kill is not prevented by Borrowed Time should Abaddon's health falls below the threshold.
Lich
[wiki] rating: -1.0 (winrate: 51% pickrate: 10%)Nature's Prophet
* Chain Frost can bounce to the treants that Nature's Prophet summons.
* Nature's Prophet's Sprout can be used to isolate and burst down the squishy Lich.
Additional:
* His treants can prevent 
Chain Frost from jumping to Nature's Prophet or his allies.
Monkey King
[wiki] rating: -0.6 (winrate: 45% pickrate: 9%)Nature's Prophet
* Sprout will not protect Nature's Prophet from Tree Dance.
* Boundless Strike will interrupt attempts at Teleportation, and can reach Nature's Prophet inside the tree line.
Nature's Prophet
* Nature's Prophet's Natures's Call can destroy trees while Monkey King is standing on them with 
Tree Dance, which will stun him for a good deal of time.
Axe
* Heroes that can keep Monkey King stunned for a long time can pose a threat: Axe, 
Centaur Warrunner.
Queen of Pain
[wiki] rating: -0.6 (winrate: 46% pickrate: 7%)Axe
* Heroes with gap closing abilities will be easy targets for Berserker's Call: 
Phantom Assassin, Faceless Void, 
Slark, Chaos Knight, Morphling, Queen of Pain
Additional:
* Berserker's Call prevents Queen of Pain from escaping with Blink and also pierces her Black King Bar.
* Due to her fast attack speed from 
Mjollnir, it will quickly trigger Counter Helix.
* Culling Blade finishes off Queen of Pain's low health pool before she gets a chance to escape, preventing her from playing the hit-and-run style often associated with Queen of Pain.
Techies
[wiki] rating: -0.6 (winrate: 47% pickrate: 7%)Nature's Prophet
* Heroes with summons like Broodmother, Enigma, Nature's Prophet; or illusions, like Naga Siren, 
Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity Mines.
Chaos Knight
[wiki] rating: -0.6 (winrate: 47% pickrate: 4%)Axe
* Heroes with gap closing abilities will be easy targets for Berserker's Call: Phantom Assassin, Faceless Void, Slark, Chaos Knight, Morphling, Queen of Pain
Additional:
* Berserker's Call allows Axe to lock down Chaos Knight and his illusions even through Black King Bar.
* Counter Helix combined with Blade Mail clears illusions out in no time.
Void Spirit
[wiki] rating: -0.6 (winrate: 47% pickrate: 7%)Axe
* Heroes with burst damage of their own won't be afraid to go toe to toe with Void Spirit, like 
Ursa, Lifestealer, or Axe.
Witch Doctor
[wiki] rating: -0.6 (winrate: 49% pickrate: 14%)Nature's Prophet
* Heroes with plenty of summons, such as Broodmother or Nature's Prophet can have their minions soak up most of your Paralyzing Cask.
Bloodseeker
[wiki] rating: -0.6 (winrate: 49% pickrate: 4%)Axe
* Heroes with high armor and durability can be exceptionally hard for Bloodseeker to bring down: Dragon Knight, Axe
Faceless Void
[wiki] rating: -0.6 (winrate: 49% pickrate: 11%)Axe
* Heroes with gap closing abilities will be easy targets for Berserker's Call: Phantom Assassin, Faceless Void, Slark, Chaos Knight, Morphling, Queen of Pain
Tusk
[wiki] rating: -0.6 (winrate: 49% pickrate: 13%)Axe
* Durable heroes can stand against Tusk during 1v1: Axe, Dragon Knight, 
Night Stalker, Centaur Warrunner, 
Wraith King and more.
Bane
[wiki] rating: -0.6 (winrate: 49% pickrate: 3%)Nature's Prophet
* Heroes with illusions and summons can swarm Bane, who has no area abilities: Broodmother, Chaos Knight, Nature's Prophet, Phantom Lancer, Terrorblade.
Pudge
[wiki] rating: -0.6 (winrate: 50% pickrate: 28%)Nature's Prophet
* Heroes with many summons or illusions are much harder to catch with Meat Hook: Nature's Prophet, Phantom Lancer, Chen.
Mirana
[wiki] rating: -0.6 (winrate: 52% pickrate: 15%)Nature's Prophet
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Lycan
[wiki] rating: -0.6 (winrate: 55% pickrate: 2%)Axe
* Melee heroes who rely on summons, illusions or clones will trigger Counter Helix more often, thus taking more damage: Meepo, Lycan, Phantom Lancer
Additional:
* Berserker's Call can keep Lycan in place during his Shapeshift even through Black King Bar.
* Counter Helix is very effective against Lycan because of his summons.
* Culling Blade will prevent Lycan from running away with Shapeshift when he drops low.
Lina
[wiki] rating: -0.4 (winrate: 47% pickrate: 12%)Nature's Prophet
* Heroes with summons can find their summons eliminated easily by Lina, like Broodmother, Nature's Prophet, and Chen.
Additional:
* Lina can easily prevent Nature's Prophet's Teleportation escape attempts with 
Light Strike Array, and can clear Sprout's trees instantly.
* Lina's 
Dragon Slave and Light Strike Array can kill Nature's Prophet's Treants.
Axe
* Axe with Berserker's Call and Blade Mail can do a lot of damage quickly due to Lina's high attack speed.
Mars
[wiki] rating: -0.4 (winrate: 47% pickrate: 12%)Nature's Prophet
* Heroes who lack burst damage will have a hard time against Mars: Phantom Lancer, Nature's Prophet, 
Lich.
Axe
* Berserker's Call forces Mars to face in the direction choosen.
* Counter Helix is a much stronger lane trader than Spear of Mars.
Anti-Mage
[wiki] rating: -0.4 (winrate: 51% pickrate: 8%)Nature's Prophet
* Anti-Mage's high mobility from Blink and tendency to build Battle Fury makes him strong against split-pushing heroes: Nature's Prophet, Tinker, and Arc Warden.
Axe
* Berserker's Call prevents Anti-Mage from escaping with Blink, and works well with Blade Mail against Anti-Mage's relatively low health.
* Counter Helix often triggers even if Axe's depleted of mana, which will make Anti-Mage take more damage than he's dealing and deals pure damage, ignoring the protection from Counterspell.
* Axe's low mana pool makes him a bad target for using Mana Void.
* Axe's high base health regeneration allows him to dominate the lane against Anti-Mage, especially with a support.
Additional:
* Berserker's Call is one of the most reliable ways to lock down Anti-Mage, preventing him from 
Blinking away.
* Anti-Mage's high attack speed, along with illusions from Manta Style, triggers Counter Helix continuously.
* Axe's low mana pool and high health pool makes 
Mana Void deal very little damage to Axe.
Slark
[wiki] rating: -0.4 (winrate: 52% pickrate: 14%)Nature's Prophet
* Pounce also stops Nature's Prophet's Teleportation.
Axe
* Berseker's Call catches Slark in 
Shadow Dance, wasting its duration and preventing him from escaping to regenerate.
* Unlike most disables, 
Dark Pact cannot dispel Berserker's Call, and the output damage would be returned by Blade Mail.
Additional:
* Berserker's Call forces Slark to attack him, even during Shadow Dance.
* Counter Helix will hit Slark in Shadow Dance. It also triggers frequently against Slark's high attack speed provided by Essence Shift stacks.
* Culling Blade finishes off Slark before he gets a chance to slip away and regenerate his health, preventing him from playing the typical hit-and-run style.
Drow Ranger
[wiki] rating: -0.4 (winrate: 53% pickrate: 17%)Axe
* Ranged heroes that can easily harass Axe: Drow Ranger, Sniper, Lion.
Axe
* Berserker's Call forces Drow Ranger to attack Axe up close, disabling her Marksmanship bonus.
* Counter Helix occurs more often with Drow Ranger's high attack speed.
* Culling Blade is a dangerous ability against a low health hero like Drow Ranger.
Riki
[wiki] rating: -0.4 (winrate: 55% pickrate: 6%)Nature's Prophet
* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin
Axe
* Axe can disable 
Cloak and Dagger's invisibility with Berserker's Call, which forces Riki to attack him at a very bad angle.
* Axe has a very high HP pool, making it hard for you to kill him before you get big items - that is if you survive engaging him. Counter Helix ignores Riki's armor and goes straight for his tiny HP pool, totally ignoring 
Smoke Screen.
* Axe is a natural buyer of Blade Mail and Riki generally does not buy lifesteal items, causing Riki to kill himself when attacking due to your tiny HP pool.
Phantom Assassin
[wiki] rating: 0.0 (winrate: 45% pickrate: 14%)Nature's Prophet
* Nature's Prophet's low mobility and health pool allow Phantom Assassin to destroy him in the early game.
* Phantom Strike allows Phantom Assassin to jump in and out of Sprout, provided she has vision.
Axe
* 
Phantom Strike's extra attack speed will cause Phantom Assassin to trigger Counter Helix more often, which can be fatal for Phantom Assassin. Jumping on Axe with Phantom Strike is not a good idea for Phantom Assassin at all as it makes her a seriously easy target for a counter-initiation with Berserker's Call and Blade Mail.
* Most of Axe's abilities pierce Black King Bar, allowing him to lock down Phantom Assassin at any time.
* Berserker's Call greatly reduces Phantom Assassin's ability to crit hard against Axe, and may cause her to kill herself when used with Blade Mail. Berserker's Call can also affect Phantom Assassin even if she has Black King Bar active as Berserker's Call can fully pierce spell immunity, making Berserker's Call one of the best abilities in the game against heroes like Phantom Assassin who wants to kill opponents quickly without being interrupted.
* Culling Blade can often kill Phantom Assassin before she can do anything due to her low health and strength gain. And every time Culling Blade successfully kills Phantom Assassin or any of her teammates, Axe gains permanent armor from it, which in combination with armor items that Axe often purchases like Blade Mail, Crimson Guard, Assault Cuirass and Shiva's Guard can make Phantom Assassin's attacks only tickle Axe.
* 
Aghanim's Shard upgraded Counter Helix can weaken Phantom Assassin's damage output, and if her attack damage is weak, 
Coup De Grace will also suffer from attack damage reduction as well.
Additional:
* Phantom Strike's extra attack speed will cause Phantom Assassin to trigger Counter Helix more often, which can be fatal for Phantom Assassin in the early game. Jumping on Axe with Phantom Strike is not a good idea for Phantom Assassin at all as it makes her a seriously easy target for a counter-initiation with Berserker's Call and Blade Mail.
* Most of Axe's abilities pierce Black King Bar, allowing him to lock down Phantom Assassin at any time.
* Berserker's Call greatly reduces Phantom Assassin's ability to crit hard against Axe, and may cause her to kill herself when used with Blade Mail. Berserker's Call can also affect Phantom Assassin even if she has Black King Bar active as Berserker's Call can fully pierce spell immunity, making Berserker's Call one of the best abilities in the game against heroes like Phantom Assassin who wants to kill opponents quickly without being interrupted.
* Culling Blade can often kill Phantom Assassin before she can do anything due to her low health and strength gain. And every time Culling Blade successfully kills Phantom Assassin or any of her teammates, Axe gains permanent armor from it, which in combination with armour items that Axe often purchases like Blade Mail, Crimson Guard, Assault Cuirass and Shiva's Guard can make Phantom Assassin's attacks only tickle Axe.
* Blade Mail is an item that Axe purchases every game, and which can be used to turn Phantom Assassin's critical strikes from Coup De Grace against herself. This can become even worse if she's affected by Berserker's Call, as she has no way to stop attacking.
* Aghanim's Shard upgraded Counter Helix can weaken Phantom Assassin's damage output, and if her attack damage is weak, Coup De Grace will also suffer from attack damage reduction as well.
Pangolier
[wiki] rating: 0.0 (winrate: 48% pickrate: 11%)Nature's Prophet
* Heroes who have summons, which can be quickly cleared by his powerful area of effect skill: Nature's Prophet, Enigma, Lycan
Axe
* Heroes with other kind of disables that pierce spell immunity can hold Pangolier in place during Rolling Thunder: Axe, Beastmaster, Enigma, Magnus, Pudge, Batrider, 
Bane, Winter Wyvern
Shadow Fiend
[wiki] rating: 0.0 (winrate: 49% pickrate: 23%)Nature's Prophet
* Shadow Fiend can easily farm his treants and get easy Necromastery Stacks.
* If Shadow Fiend buys Boots of Travel and 
Shadow Blade, he can counteract Nature's Prophet's split-push.
Axe
* Berserker's Call and Counter Helix allow Axe to kill Shadow Fiend if he stands too close to a creep wave.
* Battle Hunger is very strong against Shadow Fiend in the early game because Shadow Fiend's low attack damage makes it hard for him to get last hits.
* Axe's naturally high strength and health regeneration will be enough to tank a lot of Shadow Fiend's damage in the early game.
Io
[wiki] rating: 0.0 (winrate: 50% pickrate: 3%)Nature's Prophet
* Io can 
Relocate with an ally to gank Nature's Prophet when he tries to push.
Additional:
* Nature's Prophet is extremely easy to gank with Relocate while he's split pushing.
* Tether on a friendly unit can destroy Nature Prophet's trees should he surround himself with Sprout as a defense.
Axe
* Heroes that are hard to gank: Axe, 
Death Prophet, Phantom Lancer
Luna
[wiki] rating: 0.0 (winrate: 50% pickrate: 4%)Nature's Prophet
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include 
Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, 
Lone Druid, Chen, 
Enchantress, Meepo and Arc Warden).
Additional:
* 
Moon Glaives and 
Lunar Blessing help Luna quickly kill Nature's Prophet's treants.
* Luna can easily cancel Teleportation with her 
Lucent Beam.
Nature's Prophet
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Sven
[wiki] rating: 0.0 (winrate: 50% pickrate: 4%)Nature's Prophet
* Heroes with cleave damage: Sven, Magnus, Kunkka
Nature's Prophet
* Sprout is good for trapping melee carries with no escape abilities: Sven, Alchemist, Lifestealer etc.
Marci
[wiki] rating: 0.0 (winrate: 51% pickrate: 17%)Nature's Prophet
* Sprout can't stop her to Rebound.
* Treants can be used as targets for Rebound and Dispose as well.
Axe
* Unleash ensures that Axe's Counter Helix procs many times, even if he is stunned by Dispose.
* Aghanim's Shard allows Counter Helix to reduce the attack damage of anyone it strikes. Combined with Unleash causing to proc frequently, Marci will not be dealing significant damage as she attacks Axe over time.
* Axe doesn't worry about the damage from Unleash if he activates Berserker's Call beforehand. If he had activated Blade Mail or Mjollnir (or even both) as Marci attacks him, he will turn Unleash's high attack speed and damage against her.
* Usually, Axe would prefer to jump on his opponent to be more effective. Rebound does Axe a favor, bringing Marci within his most effective range.
Huskar
[wiki] rating: 0.0 (winrate: 52% pickrate: 5%)Nature's Prophet
* Sprout will not protect Nature's Prophet from Huskar if he has already locked on with Life Break.
* Even a farmed Nature's Prophet is usually not durable enough to fight Huskar alone.
Axe
* Huskar is often played at low health to maximize the bonuses from 
Berserker's Blood, and also because his abilities cost health to use. This makes him especially vulnerable to Culling Blade.
* Berserker's Blood gives Huskar no protection against the pure damage of Culling Blade. Its attack speed bonus also means that Counter Helix will proc more often.
* Axe's tankiness and base health regeneration makes it hard for Huskar to take him down with 
Burning Spears.
Additional:
* Berserker's Call and Blade Mail can be used immediately after Huskar jumps on Axe with Life Break.
* Huskar's high attack speed procs Counter Helix repeatedly.
* Huskar's health loss from using his abilities make him a frequent target for Culling Blade.
Arc Warden
[wiki] rating: 0.0 (winrate: 54% pickrate: 8%)Axe
* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk
Axe
* Heroes who rely on fast attack speed will also trigger Counter Helix frequently: Faceless Void, Troll Warlord, Anti-Mage, Juggernaut, Arc Warden, Morphling
Additional:
* Magnetic Field doesn't provide a protection against Berserker's Call and Counter Helix and his high attack speed together with Tempest Double will often trigger Counter Helix.
* The threat of a blink and Berserker's Call may make the real Arc Warden stay further back, thus effectively halving the team's damage output for a while.
* Axe also has the tools to even solo kill a Tempest Double, with his Manta Style and Aghanim's Shard build, and can also de-push the lanes Arc Warden shoves in.
Naga Siren
[wiki] rating: 0.0 (winrate: 54% pickrate: 6%)Nature's Prophet
* Naga Siren is a natural split-pusher. With a Radiance equipped, she will easily keep the lanes pushed out, therefore keeping backdoor protection enabled and preventing Nature's Prophet from dealing building damage.
* 
Ensnare prevents Teleportation.
* 
Song of the Siren will stop Nature's Prophet from escaping even if he has hidden inside of Sprout.
Additional:
* Naga Siren is a natural split-pusher. With Rip Tide, she will easily out-push Nature's Prophet, farming his treants in the process.
* Ensnare prevents Teleportation. Even if he hides inside Sprout, Song of the Siren lasts long enough to prevent him from escaping.
Axe
* Axe will destroy her illusions by proccing Counter Helix more often due to him being hit by more attacks.
Broodmother
[wiki] rating: 0.0 (winrate: 55% pickrate: 5%)Nature's Prophet
* Broodmother can destroy Nature's Prophet's Treants with 
Spawn Spiderlings and summon spiderlings in their place.
* Broodmother loves buying 
Orchid Malevolence, which can prevent Nature's Prophet from escaping with Sprout and Teleportation.
Additional:
* Sprout cannot protect Nature's Prophet if Broodmother puts down a web.
* Nature's Prophet's low mobility means he is defenseless against Incapacitating Bite.
* Spiderlings can absorb much of the damage from 
Wrath of Nature.
Axe
* Berserker's Call can catch Broodmother in her web, as well as groups of spiderlings. This is particularly effective when Broodmother attempts to push towers with her spiderlings.
* Counter Helix destroys spiderlings very quickly, and earns Axe a good deal of gold.
Additional:
* Berserker's Call forces Broodmother and her spiderlings to attack, allowing for large amounts of pure damage to be done through Counter Helix.
Visage
[wiki] rating: 0.0 (winrate: 56% pickrate: 5%)Nature's Prophet
* Nature's Prophet has no innate way to deal with 
Gravekeeper's Cloak or kill {U:Familiar}s effectively.
* Familiars can fly over the trees created by Sprout. They can also use 
Stone Form when Nature's Prophet is trying to use Teleportation.
Additional:
* Nature's Prophet has no natural method of dealing with Gravekeeper's Cloak and Familiars.
* Familiar's low base attack time can chip away Nature Prophet's health.
* Familiar's Stone Form destroys trees created by Sprout.
* Familiars can scout woods and foggy areas where Nature's Prophet is trying to use Teleportation.
Axe
* Axe can Berserker's Call into a flock of Familiars, proccing Counter Helix and killing them off.
* Familiars' very fast attacks will proc Counter Helix, receiving full damage due to their low attack range.
Axe
*
Ice Path is a great stun for Berserker's Call and with a 
Eul's Scepter of Divinity can really catch Axe off guard.
Dual Breath and 
Liquid Fire can be a devistating combination for Axe (especially if he takes Battle Hunger at level 1) before he has any natural regeneration sustain from items.
Ice Path neutralizes initiation attempts with Berserker's Call, and its long area of effect discourages follow-ups from Axe's teammates.
Ice Path serves as a large obstacle to stop Axe from chasing down fleeing stragglers to kill with Culling Blade.
Black King Bar, he's vulnerable to Jakiro's abilities and counter-initiaions.
*
Additional:
*
*
* Jakiro's many damage-per-second skills prevent Axe from initiating with his Blink Dagger. And since Axe rarely buys
Nature's Prophet
* Jakiro's
Macropyre can help him to escape from Sprout and quickly clears Treants.
Ice Path.
Nature's Call while simultaneously slowing Nature's Prophet, Ice Path can disrupt Nature's Prophet's escaping attempt with 
Teleportation, and Macropyre can easily clear treants from 
Nature's Call.
* Jakiro can disrupt Nature's Prophet's escape attempt with Sprout and Teleportation by using
Additional:
* Jakiro's skill arsenal can ruin Nature's Prophet's gameplay: Dual Breath and Liquid Fire can clear treants from