* Nature's Prophet can literally do nothing against Spectre, because she can chase him from anywhere with Haunt.
* Spectre, just like Naga Siren loves buying Radiance, which can kill Nature's Prophet's treants, and grant her farm simultaneously.
Additional:
* Spectre can get to him anywhere on the map with Haunt.
* Spectre can pass through his trees with Spectral Dagger.
* Desolate's damage will melt him quickly, as he's alone most of the time.

* Dispersion makes Spectre very tanky, making it much less likely for Axe to bring her low enough for Culling Blade.
* Spectre can simply use Spectral Dagger to escape against an Axe gank.

* Undying's Tombstone will cheerfully chew through treants, incidentally netting you some extra income during fights.
* The above interaction tends to ensure that skirmishes are heavily populated with units, thereby buffing Soul Rip

* Decay's stacking strength reduction makes Axe much less dominant in lane.
* Tombstone's zombies take no damage from Counter Helix, and will continuously put Axe's Blink Dagger on cooldown until dealt with.

* Jakiro's Macropyre can help him to escape from Sprout and can disrupt Nature's Prophet's jungling.
* Jakiro can disrupt Nature's Prophet's escape attempt with Teleportation with Ice Path.
Additional:
* Jakiro's skill arsenal can ruin Nature's Prophet's gameplay: Dual Breath and Liquid Fire can clear treants from Nature's Call while simultaneously slowing Nature's Prophet, Ice Path can disrupt Nature's Prophet's escaping attempt with Teleportation and Macropyre can not only clear treants from Nature's Call, but also can free Jakiro from Sprout.

* Axe is a hero that is very vulnerable against magical nuke damage and disables, Jakiro is perfect against him with all of his spells.
Additional:
* Ice Path neutralizes initiation attempts with Berserker's Call, and its long area of effect discourages follow-up from Axe's teammates.
* Ice Path serves as a large obstacle to stop Axe from chasing down fleeing stragglers to kill with Culling Blade.
* Jakiro's many damage-per-second skills prevent Axe from initiating with his Blink Dagger.

* Doom can eats Nature's Prophet's treants with Devour and gains lots of gold.
* Doom usually buys Radiance or using his Scorched Earth deals a lot of damage to Nature's Prophet if they stand close to his Treants, as well as killing all of his Treants and getting lots of gold.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Nature's Prophet:
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer, Satyr Tormenter and etc. are good examples.
* Doom and a ministun from Infernal Blade's prevents Nature's Prophet from escaping with Sprout and Teleportation.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Axe more than most normal attacks, negating some of his tankiness. With Aghanim's Scepter, Counter Helix is also disabled, making him effectively useless for a lengthy duration.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Axe.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom's naturally low attack speed makes Counter Helix less likely to proc.
* Doom makes Axe less disruptive, preventing him from using his skills or items.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Axe.
* Doom has low attack speed because of his high Base-Attack-Time, poor agility gain and limited attack-speed granting items which are commonly built. This means Doom will trigger Counter Helix less often and thus is an unideal target for initiation.
* Doom has naturally high HP so it takes longer for Doom to be brought down to the killing threshold of Culling Blade.
* Axe is highly reliant on his abilities and items to be effective during a fight. Without the usage of Berserker's Call and Blink Dagger, Axe offers very little in the way of damage.

* Clockwerk's long range initiation and catch makes it incredibly difficult for Nature's Prophet to split push and show on the map alone.

* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Firefly can be used to clear Nature's Prophet's treants and allowing to jump on Sprout.
* Flaming Lasso prevents Nature's Prophet escaping from Teleportation.

* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe

Additional:
* Timbersaw can easily cut down trees from Sprout, making it very difficult for Nature's Prophet to teleport away or trap enemies.
* Timbersaw's abilities quickly clear out treants.
* Reactive Armor negates most of the damage of Nature's Prophet's treants, and Timbersaw can often allow himself to be attacked in order to heal himself.

* Whirling Death reduces Axe's strength by 15%, making him much less tanky, especially in the early game. It is also stackable.
* Axe's Blade Mail is ineffective against attribute changes, and Timbersaw's mobility with Timber Chain means he can wait out Blade Mail's duration.
* Reactive Armor's armor and regeneration makes it much harder for Axe to finish Timbersaw with Culling Blade.
* Chakram disarms Timbersaw, making Counter Helix less effective.

* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Broodmother, Nature's Prophet, Phantom Lancer by their nature offer very good target for Splinter Blast and Winter's Curse.

* Firestorm quickly kills all the treants and increases the Atrophy Aura passive.
* Pit of Malice can stop Teleportation channeling.
* Atrophy Aura greatly reduces Nature's Prophet's damage and he has no other ways of dealing damage.
* Dark Rift can counter split-pushing, which is something that Nature's Prophet relies a lot, and Nature's Prophet has very little solutions to intercept Dark Rift.

* Omniknight's healing prevents allies from dropping low enough for Culling Blade. However, it can still go through all his buffs.
* Axe also enjoys getting close to allied heroes in order to damage them with his Counter Helix, which can easily be punished by Purification.

* Nature's Prophet treants can easily cleared by damage-over-time Ignite or Multicast Hand of Midas earning lots of gold.
* Fireblast and Unrefined Fireblast prevents or cancels out Nature Prophet from escaping with Teleportation.

* Once caught in Bear's Entangle, Nature's Prophet cannot escape with Teleportation.

* Astral Spirit can give Elder Titan a lot of damage and movement speed if Nature's Prophet stands close to his treants.
* Not only Echo Stomp can also prevent Nature's Prophet to escape Teleportation, but also, Elder Titan can also use Astral Spirit to bypass Sprout and use its own Echo Stomp.
* Aghanim's Scepter upgraded Earth Splitter can clear Nature's Prophet's treants and disarm him simultaneously, which can shutdown his pushing.

* Frequent healing from Death Pulse and Mekansm makes it difficult for Axe to finish off targets with Culling Blade.
* Ghost Shroud's instant cast time allows Necrophos to turn ethereal before being initiated on by Berserker's Call. This prevents him from attacking Axe while taunted, thus lowering the chance to proc Counter Helix.
* Axe's high health is relatively ineffective against Heartstopper Aura's percentage-based health degeneration.
* Reaper's Scythe negates Axe's tankiness, and can kill him quickly after initiation.
Additional:
* Frequent healing from Death Pulse makes it difficult for Axe to finish off targets with Culling Blade.
* Reaper's Scythe negates Axe's tankiness, and can kill him quickly after initiation.
* Heartstopper Aura is effective due to Axe's high strength gain.

* Decrepify can be used on allies to prevent them from attacking Axe and triggering Counter Helix during Berserker's Call. He can also cast it on Axe to prevent anyone from attacking him.
* Life Drain can be used to heal himself or allies caught in Berserker's Call, preventing them from dropping low enough for Axe to kill them with Culling Blade.

* Treants increase Echo Slam's damage.
* Earthshaker's AoE stuns can hit Nature's Prophet through Sprout, without having direct line of sight, in order to interrupt Teleportation.
Additional:
* Echo Slam can do a lot of damage if Nature's Prophet stands close to his treants.

* Tinker with Rearm and Boots of Travel can teleport and defend towers whenever Nature's Prophet tries to push.
* Laser prevents Nature's Prophet from attacking. Additionally, even with Monkey King Bar, Nature's Prophet cannot hit towers and buildings.
* March of the Machines can easily kill an entire wave of Treants, giving Tinker lots of gold.

* Just like Batrider, his Ball Lightning can be used clear Nature's Prophet's treants and easily destroys Sprout.
* Electric Vortex prevents Nature's Prophet's escaping from Teleportation.

* Crypt Swarm helps clear treant pushes.
* Silence prevents Nature's Prophet from using Sprout or Teleportation.
* Exorcism kills all treants.
Additional:
* Exorcism can quickly kill any Treants or Necronomicon units. Silence also prevents him from using Teleportation to escape or Sprout to lock you down.

* Sand King has many tools to deal with Nature's Prophet's treants.
* Sand King also can interrupt Teleportation with Burrowstrike.
Additional:
* With Caustic Finale, Sand King can easily kill the treants from Nature's Call.
* Burrowstrike allows Sand King to prevent Nature's Prophet from using Teleportation inside of his Sprout.

* Disruption will save Shadow Demon's teammates from being killed by Counter Helix or Culling Blade.
* Soul Catcher and Shadow Poison can put Axe's Blink Dagger on cooldown.
* Demonic Purge slows Axe to a crawl, making him nearly useless after initiating. If Shadow Demon has Aghanim's Scepter, it will also break Counter Helix.

* Sleight of Fist with Battle Fury deals a lot of damage to Nature's Prophet's team if they stand close to his Treants, as well as killing all of his Treants and getting lots of gold.
* Ember Spirit with Fire Remnant and Boots of Travel can teleport and defend tower whenever Nature's Prophet tries to push.
Additional:
* Ember Spirit can easily deal with Nature's Call by using his Flame Guard and with Battle Fury. He also has multiple ways of escaping Sprout. Additionally, Ember Spirit can break Sprout's trees with Activate Fire Remnant and interrupt Teleportation with Searing Chains.

* Mystic Snake can harass Axe in lane and drain his small mana pool.
* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to pursue.

* Outworld Devourer's pure and magical damage is particularly effective against Axe.
* Astral Imprisonment is an excellent way to defend against an initiating Axe.
* Sanity's Eclipse deals high damage to Axe due to his low mana pool.
Additional:
* Berserker's Call bonus armor doesn't block Arcane Orb's pure damage.
* Astral Imprisonment can be used to prevent an ally or Outworld Devourer himself from an Axe initiation.
* Axe's low mana means he's susceptible to a powerful Sanity's Eclipse.

* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin

Additional:
* Nature's Prophet is often by himself. Clinkz can use invisibility to hunt him down and kill him, although a Quelling Blade may be needed to cut through his Sprout. Orchid Malevolence may also be needed if 3-4 seconds are not enough time to kill him, as he can teleport away.
* Clinkz can match Nature's Prophet's ability to split push.

* Heroes with detection: Bounty Hunter, Disruptor, Razor, Slardar, Spectre, Spirit Breaker

* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe

* Most summons and illusions can barely hurt Tidehunter at all, after their attacks get reduced by Anchor Smash and blocked by Kraken Shell: Nature's Prophet, Enigma
* Also Ravage's large area of effect and damage can easily damage all those units at once, or just straight up clear them.

* Heroes with detection: Bounty Hunter, Disruptor, Razor, Slardar, Spectre, Spirit Breaker

* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin

* Hand of God and Divine Favor make it hard for Axe to finish off allies with Culling Blade.

* Heroes with cleave damage: Sven, Magnus, Kunkka

* Heroes with high health especially Strength heroes will take more damage on Sun Ray: Axe, Pudge, Bristleback, Mars.

Additional:
* Sun Ray allows Phoenix to heal any allies caught in Berserker's Call, while burning away Axe's high HP at the same time.
* Icarus Dive and Fire Spirits puts Axe's Blink Dagger on cooldown.
* Axe's slow attack speed makes it difficult for him to destroy Supernova on his own.

* Heroes with detection: Bounty Hunter, Disruptor, Razor, Slardar, Spectre, Spirit Breaker

* Heroes with summons can find their summons eliminated easily by Lina, like Broodmother, Nature's Prophet, and Chen.

Additional:
* Lina can easily prevent Nature's Prophet Teleportation escape attempts with Light Strike Array.
* Lina's Dragon Slave and Light Strike Array can kill Nature's Prophet's treants and grant her lot of farm.
* Nature's Prophet doesn't like buying Black King Bar, which is only item that can help him against Lina.

* Heroes with detection: Bounty Hunter, Disruptor, Razor, Slardar, Spectre, Spirit Breaker

* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: Broodmother, Enigma, Nature's Prophet.

* Mass summoning heroes: Broodmother, Nature's Prophet and Enigma are all able to mass-summon units, which Puck is able to clear with Illusory Orb and Waning Rift instantly, due to their summons having low health.

* Ranged heroes that can easily harass Axe: Drow Ranger, Sniper, Lion.

* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.
* In general, highly mobile heroes like Earth Spirit or Storm Spirit are at a disadvantage against X Marks the Spot.
* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.

* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe

* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe

* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Heroes that relies on armor or other type of physical damage negation are easy for Gyrocopter to take down during the early game with his magical damage: Axe, Dragon Knight, Sven.

* Poison Attack and Viper Strike slows Axe significantly, and puts his Blink Dagger on cooldown, preventing him from initiating.
* Nethertoxin can break Counter Helix.
Additional:
* Nethertoxin prevents Counter Helix from triggering, which significantly lowers Axe's damage output in the early to mid game.
* Viper's various slows and damage over time prevents Axe from initiating as well as putting his Blink Dagger on cooldown.

* Spirit Breaker can chase Nature's Prophet from anywhere on the map with Charge of Darkness, making it hard for Nature's Prophet to split-push.
* Charge of Darkness and Nether Strike gives vision of Nature's Prophet when he tries to Sprout himself and teleport away.
Additional:
* Charge of Darkness allows Spirit Breaker to catch Nature's Prophet out when he tries to split push.
* Nature's Prophet can't hide in his Sprout against Spirit Breaker, as his Charge of Darkness provides vision on its target.
* Spirit Breaker can easily cancel Nature's Prophet's Teleportation.

* Moon Glaives and Lunar Blessing help Luna to tear off Nature's Prophet's treants.
* Luna can easily cancel Teleportation with her Lucent Beam.

* Mass Serpent Ward can kill lots of treants if played defensively.
* Mass Serpent Ward, Hex and Shackles can catch and kill a Nature's Prophet trying to use Teleportation.
Additional:
* Shadow Shaman's Mass Serpent Ward together with Ether Shock can easily kill lots of Treant if played defensively.
* Mass Serpent Ward, Hex and Shackles can disrupt Nature's Prophet's escape attempt with Teleportation. Though he can Sprout himself.
* Nature's Prophet also has no ways of canceling Shackles.

* Meepo can net Nature's Prophet's treants with Earthbind and then he Poofs them. Putting an end to his pushing.
* Skilled Meepo can rival and even exceed Nature's Prophet's global presence by combining Poof with Boots of Travel, meaning that he can not only stop his push, but also can kill him if he is not careful.

* Feast's lifesteal makes it nearly impossible for Axe to initiate and bring Lifestealer's health low enough for Culling Blade, even with many procs of Counter Helix.
* Feast's damage is calculated as a percentage of health, turning Axe's high health against him. This allow Lifestealer to hit Axe much harder than most other heroes.
Additional:
* Feast makes it impossible to put Lifestealer's health for a Culling Blade and also deals high damage to Axe due to his naturally high health.
* However, Lifestealer's Rage can be pierced by Berserker's Call.

* Acid Spray and Greevil's Greed will quickly destroy pushes with treants.

* Enrage reduces the damage from Blade Mail and Counter Helix to a minimum, forcing Axe to play around Ursa's ultimate ability.
* Enrage and Fury Swipes tear through Axe's low armor, even if he has relatively high health.