* Charge of Darkness allows Spirit Breaker to gank Shadow Fiend in the early game, preventing him from getting Necromastery stacks.
* Nether Strike and Charge of Darkness can be used to prevent Shadow Fiend from casting Requiem of Souls.

* Berserker's Call and Counter Helix allow Axe to kill Shadow Fiend if he stands too close to a creep wave.
* Battle Hunger is very strong against Shadow Fiend in the early game because Shadow Fiend's low attack damage makes it hard for him to get last hits.
* Axe's naturally high strength and health regeneration will be enough to tank a lot of Shadow Fiend's damage in the early game.

* Anti-Mage usually relies on Blink to escape, but with vision from Charge of Darkness it is easier to catch him.
* Spirit Breaker could single-handedly lock Anti-Mage down for 4 seconds (or even more with lucky bashes), allowing his teammates to follow up.
* As Anti-Mage is an elusive hero who likes to farm alone, Spirit Breaker could choose to charge whenever Anti-Mage is in sight.

* Berserker's Call prevents Anti-Mage from escaping with Blink, and works well with Blade Mail against Anti-Mage's relatively low health.
* Counter Helix deals pure damage, ignoring the protection from Counterspell.
* Counter Helix will trigger even if Axe's depleted of mana, which will make Anti-Mage take more damage than he's dealing.
* Axe's low mana pool makes him a bad target for using Mana Void.
* Axe's high base health regeneration allows him to dominate the lane against Anti-Mage, especially with a support.
Additional:
* Berserker's Call is one of the most reliable ways to lock down Anti-Mage, preventing him from Blinking away.
* Anti-Mage's high attack speed, along with illusions from Manta Style, triggers Counter Helix continuously.
* Axe's low mana pool and high health pool makes Mana Void deal very little damage to Axe.

* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe

Additional:
* Berserker's Call and Counter Helix will still hit targets inside of a defensive Sprout.
* Counter Helix clears treants in no time.
* Nature's Prophet's low damage is unlikely to hurt Axe until the very late game.
* Nature's Prophet's low mobility makes him very easy for Axe to chase down or initiate on, especially when affected by Battle Hunger.

* Spirit Breaker can chase Nature's Prophet from anywhere on the map with Charge of Darkness, making it hard for Nature's Prophet to split-push.
* Charge of Darkness and Nether Strike gives vision of Nature's Prophet when he tries to Sprout himself and teleport away.
Additional:
* Charge of Darkness allows Spirit Breaker to catch Nature's Prophet out when he tries to split push.
* Nature's Prophet can't hide in his Sprout against Spirit Breaker, as his Charge of Darkness provides vision on its target.
* Spirit Breaker can easily cancel Nature's Prophet's Teleportation.

* Heroes that rely on escapes to stay alive can be caught and locked down for a long time: Queen of Pain, Phantom Assassin

* Phantom Strike's extra attack speed causes Phantom Assassin to proc Counter Helix more often. Using it on Axe also makes Phantom Assassin an easy target for a counter-initiation with Berserker's Call and Blade Mail.
* Most of Axe's abilities pierce Black King Bar, allowing him to lock down Phantom Assassin at any time.
* Berserker's Call greatly reduces Phantom Assassin's ability to crit hard against Axe, and may cause her to kill herself when used with Blade Mail.
Additional:
* Jumping in with Phantom Strike makes Phantom Assassin an exceptionally easy target for Berserker's Call.
* The bonus attack speed from Phantom Strike also means that Phantom Assassin will proc Counter Helix numerous times.
* Black King Bar is generally useless against Axe's abilities and item build, as Black King Bar doesn't prevent Axe from finishing Phantom Assassin off with Culling Blade. It also doesn't work against Berserker's Call and Counter Helix.
* Blade Mail is an item that Axe purchases every game, and it can be used to turn Phantom Assassin's critical strikes against herself. The situation becomes even worse if she's affected by Berserker's Call, as she has no way to stop attacking.

* Axe can disable Cloak and Dagger's invisibility with Berserker's Call, which forces Riki to attack him at a very bad angle.
* Axe has a very high HP pool, making it hard for you to kill him before you get big items - that is if you survive engaging him. Counter Helix ignores your armor and goes straight for your tiny HP pool, totally ignoring Smoke Screen.
* Axe is a natural buyer of Blade Mail and Riki players generally do not buy lifesteal, causing you to kill yourself when attacking due to your tiny HP pool.

* Charge of Darkness provides shared vision over its target, keeping track of heroes who rely on invisibility, mobility, or illusions: Riki, Broodmother, Phantom Lancer

* Charge of Darkness can be used to chase down Pangolier if he escapes with Swashbuckle or Rolling Thunder.
* Nether Strike ignores Rolling Thunder's spell immunity, and will still hit Pangolier if he rolls or dashes away.

* Heroes with other kind of disables that pierce spell immunity can hold Pangolier in place during Rolling Thunder: Axe, Beastmaster, Enigma, Magnus, Pudge, Batrider, Bane, Winter Wyvern

* Heroes that can keep Monkey King stunned for a long time can pose a threat: Axe, Centaur Warrunner.

* Charge of Darkness keeps vision of Monkey King, even when he is in the trees.
* Nether Strike locks onto Monkey King and focuses damage on him during Wukong's Command.

* Charge of Darkness can be used to escape or counter-initiate against a Relocate gank.
* Greater Bash and Nether Strike is devastating due to Io's low armor, and can even knock it away from tethered target.

* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer

* Berserker's Call helps locks down Phantom Lancer in a group of illusions.
* Counter Helix combined with Blade Mail clears Phantom Lancer's illusions quickly.
* Phantom Lancer's low health in the early game makes him a frequent target for Culling Blade.
Additional:
* Berserker's Call catches Phantom Lancer when he is hidden among his illusions.
* Counter Helix quickly destroys Phantom Lancer's illusion army. The more illusions there are, the more often Counter Helix is triggered.
* Phantom Lancer's low early game health makes him an easy target for Culling Blade.

* Charge of Darkness provides shared vision over its target, keeping track of heroes who rely on invisibility, mobility, or illusions: Riki, Broodmother, Phantom Lancer

* Berserker's Call and Blade Mail can be used immediately after Huskar jumps on Axe with Life Break.
* Huskar's high attack speed procs Counter Helix repeatedly.
* Huskar's health loss from using his abilities make him a frequent target for Culling Blade.
Additional:
* Huskar is often played at low health to maximize the bonuses from Berserker's Blood, and also because his abilities cost health to use. This makes him especially vulnerable to Culling Blade.
* Berserker's Blood gives Huskar no protection against the pure damage of Culling Blade. Its attack speed bonus also means that Counter Helix will proc more often.
* Axe's tankiness and base health regeneration makes it hard for Huskar to take him down with Burning Spears.

* Spirit Breaker's stuns pierce spell immunity, making him a good choice against heroes that heavily rely on Black King Bar; Huskar

* Berserker's Call can catch Broodmother in her web, as well as groups of spiderlings. This is particularly effective when Broodmother attempts to push towers with her spiderlings.
* Counter Helix destroys spiderlings very quickly, and earns Axe a good deal of gold.
Additional:
* Berserker's Call forces Broodmother and her spiderlings to attack, allowing for large amounts of pure damage to be done through Counter Helix.

* Charge of Darkness provides shared vision over its target, keeping track of heroes who rely on invisibility, mobility, or illusions: Riki, Broodmother, Phantom Lancer

* Heroes with long-lasting, undispellable debuffs will pinpoint the true Naga Siren: Spirit Breaker, Bloodseeker.

* Axe will destroy her illusions by proccing Counter Helix more often due to him being hit by more attacks.

* Axe can easily close the distance to Sniper with either Blink Dagger or Shadow Blade.
* With Berserker's Call in combination with Counter Helix and Battle Hunger, Axe can make short work of Sniper, finishing him off easily with Culling Blade due to his low HP & high attack speed in the late game.

* Spirit Breaker can charge towards Sniper from anywhere on the map with Charge of Darkness.
* Greater Bash deals magical damage, which can prove dangerous to Sniper and his low health.
* Both previous abilities combined with Nether Strike ensures that Spirit Breaker can easily solo kill Sniper.

* Magic Missile has a considerably long cast time, making it difficult to stop Charge of Darkness with it.
* Other than Magic Missile, Vengeful Spirit has no way of canceling Nether Strike.

* Terrorblade's low base health and lack of mobility make him an easy target for Axe to initiate on, and kill.
* Counter Helix will trigger from, and destroy many of Terrorblade illusions.
Additional:
* Berserker's Call and Counter Helix together can be devastating to Terrorblade, especially if Terrorblade has a lot of illusions. Their high attack speed will trigger Counter Helix a lot, and the pure damage will quickly slice through Terrorblade's low health and kill his illusions.
* Culling Blade finishes off Terrorblade before he has the chance to Sunder due to his low health in the early to mid game.

* Berserker's Call forces Drow Ranger to attack Axe up close, disabling her Marksmanship bonus.
* Counter Helix occurs more often with Drow Ranger's high attack speed.
* Culling Blade is a dangerous ability against a low health hero like Drow Ranger.

* Generally, heroes that can close the gap on Drow Ranger to cancel her Marksmanship such as Phantom Assassin, Spirit Breaker, and Tusk are effective at limiting her power and bursting her down.

* Berserker's Call forces Mars to face in the direction choosen.
* Counter Helix is a much stronger lane trader than Spear of Mars.

* False Promise will not save an ally from Culling Blade if their health is low enough.
* Fate's Edict, offensively or defensively, does little to protect Oracle's allies from the majority of Axe's damage.

* Windrun does not provide protection against Counter Helix and Berserker's Call. Her fast attack speed with Focus Fire will also quickly trigger Counter Helix multiple times.

* Culling Blade ignores Borrowed Time should Abaddon's health falls under the threshold.
Additional:
* Culling Blade's instant kill is not prevented by Borrowed Time should Abaddon's health falls below the threshold.

* Berserker's Call and Counter Helix makes short work of Chaos Knight's Phantasms.
Additional:
* Berserker's Call allows Axe to lock down Chaos Knight and his illusions.
* Counter Helix combined with Blade Mail clears illusions out in no time.

* Troll Warlord has significant attack speed due to Fervor and Battle Trance, giving Axe a higher chance to proc Counter Helix and seriously injure Troll Warlord due to his relatively low maximum health.
* Axe often purchases Blade Mail, which can help Axe turn Troll Warlord's farm and high physical damage against him. The bonus armor provided by Berserker's Call means that Troll Warlord will take a lot more damage than Axe.
* Culling Blade is still capable of killing Troll Warlord during Battle Trance if his HP is low enough.
Additional:
* Troll Warlord's high attack speed means Counter Helix will proc extremely frequently even without creeps near him. This, combined with a Blade Mail means Axe can easily solo kill Troll Warlord even in later stages of the game.
* Battle Trance does not save Troll Warlord from a Culling Blade.

* Berserker's Call pierces spell immunity, making a Blade Fury teleport escape impossible. It's very useful against Omnislash as well.
* Juggernaut's low base health and high attack speed causes him to take a lot of damage from the pure damage of Counter Helix.
* Axe is a common Blade Mail and Blink Dagger carrier making him a very big potential threat before Juggernaut get his items.

* Possibly Clinkz's worst enemy. He has many tools to utterly destroy Clinkz.
* Charge of Darkness can be used on Clinkz if Spirit Breaker's team spots him anywhere. This charge will track his location through Skeleton Walk's invisibility and movement speed bonuses.
* When Spirit Breaker charges onto Clinkz, he can easily use Dust of Appearance to guarantee a reveal on him while stunned.
* All three of Spirit Breaker's spells help him and his team quickly close the gap to Clinkz even at the edge of his attack range or when running away with Skeleton Walk.
* Spirit Breaker's high strength and above average armor makes him able to endure Clinkz's onslaught, meanwhile Clinkz will be heavily threatened if Spirit Breaker procs a Greater Bash.
Additional:
* Once caught with dust, Clinkz could be locked down for a long time by Spirit Breaker and has nowhere to escape.
* Charge of Darkness provides shared vision over its target, showing Clinkz even when he is in Skeleton Walk.

* Tinker relies on his high mobility from Boots of Travel and Blink Dagger to survive. Those items don't help him if Spirit Breaker manages to cast Charge of Darkness on him.
* Spirit Breaker can easily cancel Rearm and Boots of Travel.

* Spirit Breaker's Charge of Darkness semi-reveals Bounty Hunter, taking away his element of surprise for the duration of the charge. Also, as Charge of Darkness shows Bounty Hunter's position, Spirit Breaker's allies can proceed to gank Bounty Hunter while he is roaming alone.

* Axe can Berserker's Call into a flock of Familiars, proccing Counter Helix and killing them off.
* Familiars' very fast attacks will proc Counter Helix, receiving full damage due to their low attack range.

* Heroes with gap closing abilities will be easy targets for Berserker's Call: Phantom Assassin, Faceless Void, Slark, Chaos Knight, Morphling, Queen of Pain

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Heroes that rely on escapes to stay alive can be caught and locked down for a long time: Queen of Pain, Phantom Assassin

* Heroes with gap closing abilities will be easy targets for Berserker's Call: Phantom Assassin, Faceless Void, Slark, Chaos Knight, Morphling, Queen of Pain

Additional:
* Berserker's Call prevents Queen of Pain from escaping with Blink and also pierces her Black King Bar.
* Due to her fast attack speed from Mjollnir, it will quickly trigger Counter Helix.
* Culling Blade finish off Queen of Pain's low health pool before she gets a chance to escape, preventing her from playing the hit-and-run style often associated with Queen of Pain.

* Techies struggles early game against heroes with naturally large strength and health regeneration such as Pudge, Axe or Ogre Magi, as the player is forced to lay down more mines than usual to kill these bulkier heroes.

* Heroes with burst damage of their own won't be afraid to go toe to toe with Void Spirit, like Ursa, Lifestealer, or Axe.

* Durable heroes can stand against Tusk during 1v1: Axe, Dragon Knight, Night Stalker, Centaur Warrunner, Wraith King and more.

* Warlock is a very strong hero when positioned correctly, and his long cast range helps him with this. However, some Heroes might disrupt or sneakily pass through your allies and deal with you, preventing you from doing your job. Such heroes include Chaos Knight, Spirit Breaker, Riki, and some others.

* Because Templar Assassin does not have escape potential in lane, any support hero with roaming potential and a Dust of Appearance can be great at shutting her down early game: Earth Spirit, Spirit Breaker, Tusk, Bounty Hunter, Riki, Warlock.

* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki

* Bristleback, Centaur Warrunner, Spirit Breaker, Pudge, Huskar: These heroes are too tanky for Puck to burst down. Also, all of them have spells which can deal with and shut Puck down reliably.

* Heroes with mobility/escape mechanisms to dodge Ancient Apparition abilites, or to easily jump on him: Riki, Queen of Pain, Phantom Assassin, Windranger, Bounty Hunter, Spirit Breaker, Night Stalker, Storm Spirit, Juggernaut, etc.

* Melee heroes who rely on summons, illusions or clones will trigger Counter Helix more often, thus taking more damage: Meepo, Lycan, Chaos Knight, Phantom Lancer

Additional:
* Berserker's Call can keep Lycan in place during his Shapeshift even through Black King Bar.
* Counter Helix is very effective against Lycan because of his summons.
* Culling Blade will prevent Lycan from running away with Shapeshift when he drops low.

* Jumping on Axe from Waveform he will be an easy target for a counter-initiation with Berserker's Call.
* Morphling is often played at low health to maximize the bonuses from Attribute Shift (Agility Gain), and also because his abilities cost health to use. This makes him especially vulnerable to Culling Blade.
* However, Morphling is common Linken's Sphere carrier to block Culling Blade forces Axe to use Battle Hunger to pop the Spell Block first.
* Attribute Shift (Agility Gain) gives Morphlig no protection against the pure damage of Culling Blade. Its attack speed bonus also means that Counter Helix will proc more often.

* Culling Blade ignores the protection from Shallow Grave, and will kill any target whose health is low enough. This makes Axe one of the hardest counters to Dazzle, and he neutralizes one of Dazzle's most important abilities.
Additional:
* Culling Blade kills any target under the health threshold, even through Shallow Grave.

* Berseker's Call catches Slark in Shadow Dance, wasting its duration and preventing him from escaping to regenerate.
* Unlike most disables, Dark Pact cannot dispel Berserker's Call, and the output damage would be returned by Blade Mail.
Additional:
* Berserker's Call forces Slark to attack him, even during Shadow Dance.
* Counter Helix will hit Slark in Shadow Dance, with pure damage. It also triggers frequently against Slark's high attack speed after having stolen agility with Essence Shift.
* Culling Blade finishes off Slark before he gets a chance to slip away and regenerate his health, preventing him from playing the hit-and-run style often associated with Slark.

* Berserker's Call is one of the best ways to lock down Weaver before he has a chance to use Time Lapse. It can also catch Weaver in Shukuchi.
* Weaver's high attack speed, along with high attack damage from Geminate Attack, triggers Counter Helix continuously and the output damage would be returned by Blade Mail.
Additional:
* Berserker's Call is one of the best ways to lock down Weaver before he has a chance to use Time Lapse. It can also catch Weaver in Shukuchi.
* Due to his fast attack speed from Geminate Attack and items that give attack speed, Counter Helix will activate a lot, and the damage would be returned by Blade Mail, which hurts Weaver far more than it hurts Axe.
* Culling Blade can finish off Weaver's low health pool before he escapes with Shukuchi and Time Lapse.
* Battle Hunger is a good tool to pop Weaver's Linken's Sphere due to its low cooldown.

* Melee heroes who rely on summons, illusions or clones will trigger Counter Helix more often, thus taking more damage: Meepo, Lycan, Chaos Knight, Phantom Lancer

Additional:
* The combination of Counter Helix and Berserker's Call can disable multiple Meepos and deal heavy area damage.
* Axe's natural high survivability makes it difficult to burst him down with Poof or chip away at his health with Ransack.

* Heroes who can stun multiple units at once: Dark Willow, Spirit Breaker, Slardar, Invoker, and Tidehunter.

* Pudge, Legion Commander and Axe will make the match a living hell for you, since they are known for surprise attacks from the fog and quickly killing low HP heroes. They can also interrupt your channeling, Legion being especially problematic, as she can use Press the Attack on an ally who is hexed as well.

* Heroes that are squishy by nature are an easy target for Spirit Breaker: Sniper, Drow Ranger, Shadow Shaman

* Spirit Breaker's Nether Strike with Aghanim's Shard disables Bristleback's passives.

* Axe forces Bristleback to turn around with Berserker's Call, allowing allies to attack him without fear of his passive.

* Heroes with high armor and durability can be exceptionally hard for Bloodseeker to bring down: Dragon Knight, Axe

* Berserker's Call forces Dark Willow to attack, cancelling Shadow Realm.