* Enigma's Eidolons can help soak Juggernaut's Omnislash in the early game, mitigating the damage and wasting it on disposable summons. Should Juggernaut choose to kill your Eidelons with Blade Fury, he leaves himself open to your disables.
* Enigma's Black Hole and Midnight Pulse damage can pierce through Juggernaut's Blade Fury.

* Fiend's Grip and an Aghanim's Scepter upgraded Brain Sap pierces spell immunity, rendering Blade Fury nearly useless.

* Heroes with channeling spells because Shadow Fiend has nothing to cancel channeling: Bane, Enigma, Pudge, Shadow Shaman.

* Enfeeble can be used to decrease Shadow Fiend's already abysmal level one damage even further, preventing him from getting farm and Necromastery stacks.
* Brain Sap allows Bane to heavily harass Shadow Fiend.
* Nightmare allows Bane to set up some early ganks onto Shadow Fiend.
* Fiend's Grip enables Bane to completely take Shadow Fiend out of a fight and potentially even kill him, even through Black King Bar.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Malefice keeps Tree Dance on cooldown, and can interrupt Wukong's Command's long cast time.
* Midnight Pulse destroys a large amount of trees.
Additional:
* Malefice will cause Monkey King to struggle without Black King Bar, as its periodic damage and stun disables/interrupts abilities, such as Tree Dance and Wukong's Command.
* Midnight Pulse also destroys trees in a wide radius, stunning Monkey King if he happened to be on a tree caught within that AoE.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge.

* Nightmare and Fiend's Grip can ground Phantom Assassin, who normally blinks around with Phantom Strike, and stop her from outputting damage, even with Black King Bar.
* Phantom Assassin's low health pool early on makes her susceptible to Brain Sap and Fiend's Grip's heavy nuke damage.
Additional:
* Nightmare's lengthy duration prevents Phantom Assassin from finishing off a target enemy hero.
* Brain Sap's deals high magical damage against Phantom Assassin in the early game. When upgraded with Aghanim's Scepter, it can pierce spell immunity.
* Fiend's Grip can disable Phantom Assassin, even through spell immunity.

* Lacking any stun and being heavily dependent on his physical attacks and spell immunity, Lifestealer has no way to stop Black Hole, assuming he does not initiate Enigma first with Abyssal Blade.
* Enigma's abilities, with exception of Malefice, can pierce spell immunity and deal pure damage (and percentage-based damage in Midnight Pulse's case), putting Lifestealer in potentially adverse situations.

* Heroes with spell immunity can still be disabled by Fiend's Grip: Juggernaut, Lifestealer, Pangolier.

Additional:
* Fiend's Grip can disable Lifestealer through Rage.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.

* Viper cannot interrupt heroes with powerful channeling abilities: Bane, Enigma, Shadow Shaman, Warlock

* Viper cannot interrupt heroes with powerful channeling abilities: Bane, Enigma, Shadow Shaman, Warlock

* Heroes with the capability of removing or destroying trees greatly hinders the effectiveness of Treant Protector's abilities: Batrider, Nature's Prophet, Lina, Enigma, Mars

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Bane's Enfeeble makes Ursa more susceptible to disables as it reduces Status Resistance.
* Bane can use Nightmare and Fiend's Grip to lock down Ursa early game and in team fights, forcing Ursa to buy a Black King Bar and making him very vulnerable to being kited once his Black King Bar is down to 5 seconds.
* Overall, Bane's potent disables force Ursa to build more defensive items and play more defensively in general.

* Nightmare and Fiend's Grip help to control/disable Troll Warlord in team-fights.

* Her illusions are easily dealt with area damage effects.
* Naga Siren won't have much option to recover from a bad position unless she built up a few key items in mid-game.

* Brain Sap's magic damage ignores stacks of Reactive Armor.
* Nightmare prevents Timbersaw from using Timber Chain, setting him up for chain stuns and burst damage.
* Fiend's Grip immobilizes Timbersaw and drains his low mana pool, preventing escape afterwards. It also pierces Black King Bar.
* Bane's multiple disables often force Timbersaw or his teammates to spend gold on a Linken's Sphere.

* Fiend's Grip and Nightmare are very useful to lock down Void Spirit.
* Brain Sap can be difficult for Void Spirit to deal with in the laning stage.

* One of the slowest heroes fall prey to an area nuke quickly when caught off-guard.

* His ultimate will be a double edged sword for him if he ever dares to use it by risking max health based damage of Enigma.
* Enigma can mass ranged summons which he's rather helpless against.

* Malefice prevents Spirit Breaker from using his spells for the duration.
* Demonic Conversion's eidolons have high magic resistance, receiving little damage from Charge of Darkness.

* If Bane is outside Chronosphere, he can use Nightmare or Fiend's Grip to cripple Faceless Void inside.
* Nightmare and Fiend's Grip are long duration disables and can render Time Walk's mobility very unreliable.

* She will be not able to cast her ultimate while under Malefice's debuff.
* Enigma's Black Hole can cancel Freezing Field's channeling regardless of her Glimmer Cape and Black King Bar.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Heroes with other kind of disables that pierce spell immunity can hold Pangolier in place during Rolling Thunder: Axe, Beastmaster, Enigma, Magnus, Pudge, Batrider, Bane, Winter Wyvern

* Heroes with other kind of disables that pierce spell immunity can hold Pangolier in place during Rolling Thunder: Axe, Beastmaster, Enigma, Magnus, Pudge, Batrider, Bane, Winter Wyvern

* Heroes with summons like Broodmother,Enigma, Invoker, Nature's Prophet, Lycan, Visage;or illusions, like Naga Siren, Phantom Lancer, Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity mines in the early game.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Heroes who possess abilities that can save targets from being killed by Reaper's Scythe: Abaddon, Bane, Outworld Devourer, Shadow Demon, Omniknight, etc.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* After Brewmaster has committed Thunder Clap and Cinder Brew to gank, Bane can use Nightmare on Brewmaster to wait out the debuffs, and might even turn the tables by buying time for allied reinforcements.
* Bane can also prevent Brewmaster from using Primal Split with his long disables.

* Can cast Demonic Conversion on one of Lycan's Wolves, making this a numbers fight.
* Malefice will greatly reduce his ability to engage
* Midnight Pulse can steep an area making it harder for Lycan to engage in.

* Enfeeble, Nightmare and Fiend's Grip all prevent Legion Commander from winning Duels, especially when Bane has Blink Dagger.
Additional:
* Bane has powerful single-target abilities that can help his allies win Duels, or at least cripple Legion Commander for the duration.
* Nightmare can waste Duel's entire duration as the dueled units transfer the Nightmare back and forth. This may be prevented if a non-Dueling unit attacks the Nightmared Dueler.

* The area of effect damage from Midnight Pulse and Black Hole help deal with Chaos Knight's illusions.
Additional:
* Black Hole usually catches Chaos Knight with all his illusions.
* Midnight Pulse deals damage based on max health, quickly killing Phantasm illusions.

* Heroes under Guardian Angel can be still damaged from the pure damage of Black Hole and Midnight Pulse.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Fiend's Grip provides mana drain, which can heavily damage Mana Shield and prevent Medusa from using Stone Gaze.
* Even if she does use Stone Gaze, Nightmare can buy enough time to protect allies and reset the fight.
Additional:
* His Fiend's Grip will leave Medusa defenseless after he's done, if his teammates can provide cover for him or he initiates at the right time by Spell immunity.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Fiend's Grip's very long disable prevents Anti-Mage from Blinking away or using Manta Style. It also pierces spell immunity.
* Nightmare sets Bane's team up for chain disables on Anti-Mage.
* Enfeeble lowers Anti-Mage's status resistance and magic resistance, making him more vulnerable to disables and magic damage that normally would not affect him much.

* Heroes that wish to disrupt fights with spell combos or big ultimates are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Devourer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.