* Tidebringer will deal lots of damage to Alchemist before he builds physical survivability items.
* Torrent and X Marks the Spot can control Alchemist at all stages of the game before he has Black King Bar.
* Ghostship's rum buff will greatly reduce the Alchemist's damage output in teamfights including his Radiance.

* X Marks the Spot breaks Flaming Lasso when used on ally and can break if used on Batrider.

* Dark Pact can dispel Flaming Lasso if is used in anticipation, but a Blink initiation from fog can catch the Slark off guard.
* Slark can also take off any Sticky Napalm stacks with Dark Pact in lane.
Additional:
* Sticky Napalm is dispelled by Dark Pact, without it, Batrider will not be as threatening
* Shadow Dance's passive can inform Slark when he's under enemy vision, meaning it'll be very hard to catch Slark off-guard with Flaming Lasso
* Flaming Lasso is dispelled by Dark Pact, its casting can be prevent with Shadow Dance or Depth Shroud (it requires Aghanim's Shard)

* Shadow Dance allows Slark to not be targeted by Unstable Concoction, making Alchemist stun himself and making himself vulnerable to the enemy.
* Dark Pact also allows him to just purge off the stun if timed correctly.
* Essence Shift will steal stats over long durations at a time should Alchemist lack the damage to kill Slark.

* Heroes without an escape mechanism: Shadow Fiend, Alchemist

Additional:
* Chemical Rage will rarely save Alchemist against Ursa's Fury Swipes.
* Enrage allows Ursa to both be a threat to Alchemist and avoid his over time damage.

* Enrage with Aghanim's Scepter can dispel Flaming Lasso.

* Time Lapse with Aghanim's Scepter dispels Flaming Lasso when used on allied hero.
* Linken's Sphere is core item for a Weaver making him a hard target for Lasso during entire game.

* Aphotic Shield and Borrowed Time can both dispel Flaming Lasso.
Additional:
* Sticky Napalm, Flaming Lasso, and Flamebreak can all be instantly dispelled by Aphotic Shield.
* Firefly will continuously heal Abaddon under Borrowed Time.

* Reaper's Scythe can kill Alchemist before Chemical Rage has the time to heal him.
* Ghost Shroud can prevent Alchemist from attacking Necrophos, as well as make him immune to Acid Spray and Unstable Concoction damage.
* Heartstopper Aura will do damage as long as Necrophos is alive based on health percentage, which is a problem for a strength hero such as Alchemist.

* Skywrath Mage can easily harass Alchemist in the laning phase with multiple Arcane Bolts. Additionally, if Alchemist is in the process of throwing an Unstable Concoction, and has no way to dispel Ancient Seal, the self stun becomes an easy set up for Mystic Flare.
* Caution, however, as a decently farmed Alchemist with {Item ID:Radiance} and {Item ID:Manta Style} can easily send illusions to harass and force Skywrath Mage out.

* With her Nether Swap, Vengeful Spirit can save the life of an ally who gets caught with Flaming Lasso. Nether Swap also makes it highly dangerous for Batrider to attempt a lasso, as it can lead to his own demise far behind enemy lines.
* Wave of Terror's flying vision allows Vengeful Spirit to spot Batrider trying to close in on his target with Firefly.
Additional:
* Nether Swap breaks Flaming Lasso when used on ally and can break if used on Batrider.
* Vengeful Spirit can disable Batrider's Blink Dagger before a fight with Wave of Terror.

* Plague Wards are very hard for Batrider to play against as they provide a lot of vision as well as disable Blink Dagger for a long duration.

* Nyx can walk into Firefly with Spiked Carapace and stun Batrider if he has no Spell Immunity.

* Feast is good against high health strength heroes such as Alchemist.
* Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.

* Corrosive Haze followed by Slithereen Crush takes advantage of Alchemist's main weakness, being physical damage before he has the change to improve his surviability with items.
* Bash of the Deep will deal lots of damage during the laning phase.

* Press the Attack dispels Flaming Lasso.
* Batrider is unlikely to win a Duel in any stage of the game.

* Alchemist's reliance on fast attack speed to do single-target damage makes him vulnerable to Static Link. It also goes through Black King Bar, which is a standard item on Alchemist.
* Eye of the Storm is great against high health strength heroes as it reduces their survivability to physical damage.
* Razor has early lane push to counter Acid Spray.

* Quas-Exort Invoker can win the mid lane easily against Alchemist because Quas regeneration will nullify Acid Spray's damage over time and Exort damage bonus will allow Invoker to out last hit Alchemist.

* Alchemist is a well-known Radiance carrier among other auras your illusions will benefit from. They also get the extra move speed and reduced base attack time from his Chemical Rage, and it's even better if you can catch him as his own rage is about to expire.
* Disruption will buy enough time for all allies to retreat when Alchemist starts to activate Unstable Concoction.

* Shadow Demon, Outworld Destroyer and Tusk can all save a Lasso'd teammate with their defensive spells.

* False Promise dispels Flaming Lasso.
* Fortune's End can root Batrider after he uses Flaming Lasso. It can also dispel Sticky Napalm and Flamebreak.
* Fate's Edict when used on a Lasso'd target will leave them immune to magical damage, making it difficult to burst them quickly before the Lasso ends.

* Ember's magic damage build is able to burst down Alchemist due to his low strength gain and Alchemist's normal item pick up.

* Kraken Shell is very useful against Sticky Napalm and Flamebreak, easily dispelling them regularly.
* Tidehunter is probably the worst hero to target with Flaming Lasso, as Kraken Shell will remove it and Tidehunter often survives long enough to cast Ravage in the middle of Batrider's team. At the same time, if Batrider initiates on his teammate, Tidehunter will have the perfect opportunity to counter-initiate.
Additional:
* Kraken Shell can dispel Flaming Lasso.
* If Batrider drags Tidehunter back towards his team, it can be setup for a well placed Ravage.

* Untouchable greatly reduces Chemical Rage's attack speed advantage.

* Zeus is good against heroes that juke in trees or up cliffs, like Batrider, Monkey King, Spectre, and Tinker, by providing vision in any area with Lightning Bolt, or guaranteeing vision on enemies with Thundergod's Wrath.

* Clinkz can use Burning Army in teamfights which will cause a problem for Alchemist.

* Visage can quickly kill heroes with low to medium base armor and no innate escape mechanism. Examples include Alchemist, Crystal Maiden and Zeus.

* Shadow Demon, Outworld Destroyer and Tusk can all save a Lasso'd teammate with their defensive spells.

* In general, attacks of the melee heroes who are entirely reliant on dealing physical damage and/or have very little to no area-of-effect abilities will make Underlord tickle and will have no effect against him, and will be unable to ambush Underlord and his team if Underlord chooses to use Dark Rift to get to a designated point of the map: Phantom Assassin, Terrorblade, Troll Warlord, Drow Ranger, Phantom Lancer, Chaos Knight, Sven, Wraith King, Bounty Hunter, Alchemist, Templar Assassin, Nyx Assassin, Bane.

* Death Prophet is a terrible Flaming Lasso target if Exorcism has already been used, since it can still damage Batrider and his teammates, but if Batrider manages to Lasso her before that, it can lead to Death Prophet being quickly burst down.

* Pugna's Decrepify makes sure that either Alchemist is unable to hit anyone while also being slowed and susceptible to magical damage, or can protect an ally from physical attacks. Besides, Pugna can push early on, when Alchemist is not strong enough to repel it, so by the time Alchemist comes online, he might be forced to sit in base.

* Shadow Demon, Outworld Destroyer and Tusk can all save a Lasso'd teammate with their defensive spells.

* Melee heroes that get kited easily have hard times dealing with Puck without any lockdowns, as Puck is one of the most mobile heroes. Heroes like Sven, Lifestealer, Ursa and Alchemist may have problems to get to Puck without proper initiation items. They also lack reliable lockdowns, as their disables are easily avoidable for Puck, or are just a soft disable.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Ice Blast nullifies the health regeneration granted by Chemical Rage, which Alchemist greatly relies on to stay alive in battle.
* Alchemist tends to build Armlet of Mordiggian which can be deadly during Ice Blast.
Additional:
* Ice Blast cancels out Chemical Rage's rapid health regeneration. It can also take advantage of Alchemist's Armlet of Mordiggian toggling, as it will make HP drain insanely fast, essentially killing the bearer in no time.