* Alchemist can easily farm Spiderlings with Acid Spray and Greevil's Greed.
* Alchemist's Chemical Rage nullifies Broodmother's Insatiable Hunger
Additional:
* Greevil's Greed makes Broodmother’s spiderlings far more valuable to Alchemist making it important that he does farm them as opposed to other heroes where the spider's bounties are negligible.
* Acid Spray makes it difficult to attack Alchemist in lane without losing some spiderlings to the damage over time, potentially giving him farm he wouldn't have otherwise.

* Chemical Rage will take down Tombstone in no time.
Additional:
* With Greevil's Greed, Alchemist can farm Tombstone zombies and gain a significant gold advantage.

* Death Pulse can easily wipe out Broodmother's spiderlings if they're too close while also offering Necrophos a source of regeneration for Broodmother's harass in lane.
* Ghost Shroud prevents Broodmother or her spiderlings from damaging Necrophos temporarily.
* Heartstopper Aura will regenerate lost health and mana for every spiderling or spiderite Necrophos manages to kill.

* Necrophos is a dangerous opponent to go against with. Regardless of how many strength Undying has gained from Decay, Necrophos can finish off Undying with Reaper's Scythe once Undying's HP falls below a certain threshold.
* Heartstopper Aura will do more damage to Undying if he gained strength from Decay, as it does damage based on a hero's maximum health.

* Zombies summoned from Tombstone will amplify the damage of Echo Slam due to them increasing the echo damage.

* Echo Slam's damage potential increases phenomenally due to Broodmother's hordes of spiderlings and spiderites.
* Long ranged Fissures can hit Broodmother if she runs into the treeline at the edges of the map.
Additional:
* Aftershock in combination with Enchant Totem prevents Broodmother from continuing to attack Earthshaker without being repeatedly stunned.
* Echo Slam is greatly amplified by Spiderlings, often instantly killing Broodmother, her swarm, and anyone else unfortunate enough to be nearby.
* Earthshakers vast amount of stuns makes it difficult for Broodmother to continue attacking enemies (to continue lifestealing with Insatiable Hunger) without Black King Bar.

* Heroes with no AoE abilities will struggle against Phantom Lancer: Clinkz, Phantom Assassin, Broodmother

* Phantom Lancer's many illusions will easily destroy Tombstone, provided he has sufficient farm.

* Spiderlings deal almost no damage against Reactive Armor. They also die quickly from Timbersaw's AoE abilities.
* Broodmother has no mobility ability except the movement speed buff from Spin Web, allowing Timbersaw to easily escape her Incapacitating Bite with Timber Chain.
* Timbersaw's tree-cutting abilities makes it difficult for Broodmother to hide, especially near the edges of the map.
Additional:
* Reactive Armor prevents Broodmother's spiderlings from being able to effectively harass Timbersaw in the lane.
* Timber Chain's high mobility makes Incapacitating Bite's slow irrelevant.
* Timbersaw's abilities can destroy any trees that Broodmother attempts to hide in and his AoE abilities can quickly clear her Spiderlings.

* Reactive Armor makes Timbersaw very effective against heroes that control a lot of units, such as Broodmother, Lycan and Undying.

* Earthbind prevents Broodmother from escaping Meepo's attacks.
* Poof will quickly clear any nearby spiders.
* Broodmother wants to pick off single target heroes. With Meepo's Divided We Stand, it gets a lot harder once every Meepo Poofs in.

* Meepo can quickly destroy Tombstone thanks to Divided We Stand.

* Heroes with summons that are destroyed by a fixed number of attacks: Undying's Tombstone, Gyrocopter's Homing Missile, and Zeus's Nimbus.

* Heroes reliant on illusions or summons: Broodmother, Chaos Knight, Naga Siren.

* Ice Blast prevents Insatiable Hunger lifesteal, Spin Web regeneration and quickly kills spiderlings.

* Due to Fervor and Battle Trance, Troll Warlord has a significant attack speed, enabling him to crush Tombstone quickly.
* Undying usually stays at the front line with no disables, making him an easy target for Troll Warlord.

* Ion Shell zones out Broodmother in the laning phase, and can kill her spiderlings if used on one Spiderling in a group.
* Vacuum can pull Broodmother out of the treeline.
Additional:
* Ion Shell is a very powerful weapon against Broodmother's Spiderlings and makes her laning much harder.

* Caustic Finale allows Sand King to easily kill Broodmother's Spiderlings throughout the game.
* Sand King can usually catch a split pushing Broodmother with Blink Dagger and Burrowstrike.
Additional:
* Burrowstrike can be used as an escape or initiation against Broodmother.
* Sand Storm quickly kills any spiderlings caught inside if Sand King can manage to stun them.

* Geminate Attack works on Tombstone, allowing Weaver to kill it quickly.
* Zombies attacking Weaver disappear once he goes invisible with Shukuchi.
* Undying has no way to catch a mobile Weaver.

* Your AoE abilities should make quick work of her spiderlings.

* Broodmother and her Spiderlings need to be very careful during the laning stage against Jakiro, as Jakiro can take down Broodmother's Spiderlings, preventing her from pushing.

* Flak Cannon rips through Tombstone's zombies.
Additional:
* Flak Cannon enables Gyrocopter to clear the zombies easily.

* Kraken Shell makes Tidehunter take nearly no damage from Spiderlings.
* Anchor Smash kills Spiderlings in one or two casts, should Broodmother try to swarm Tidehunter with them.

* Void Spirit's AoE damage make short work of Broodmother's spiderlings
* Broodmother cannot escape Void Spirit's mobility, even in her webs.
Additional:
* Void Spirit's AoE damage make short work of Broodmother's spiderlings
* Broodmother cannot escape Void Spirit's mobility, even in her webs.

* Echo Stomp can impede Broodmother's ability to push towers due to its low cooldown and long sleep duration.
* Astral Spirit can provide Elder Titan large amounts of damage, armor, and movement speed from her spiderlings.
* Natural Order negates Broodmother and her spiderling's base armor and magic resistance, increasing most damage dealt to them.

* Swashbuckle and Shield Crash quickly destroys Broodmother's spiderlings and spiderites.
* Lucky Shot's disarm is very valuable when dealing with a Broodmother during her Insatiable Hunger.
Additional:
* Swashbuckle can be used for Pangolier to escape or kill Broodmother's spiders. Combined with Lucky Shot Pangolier can potentially disarm Broodmother preventing her from lifestealing off enemies.
* Shield Crash can be used for wave clear to deal with Broodmother's spiders.
* Rolling Thunder can be used as an escape or a means of initiating on Broodmother.

* Tombstone's zombies rarely inhibit Anti-Mage, as he can either Blink away or onto the Tombstone and destroy it.

* Ball Lightning and Electric Vortex will catch Broodmother before she has a chance to retreat, and is able to catch her through the trees.
* Conversely, Ball Lightning also allows him to easily escape Broodmother, as she has no way to prevent him from using it before getting Orchid Malevolence.

* Overwhelming Odds is great at killing many stacked up spiderlings, thus giving Legion Commander a large buff.
* Duel is a reliable way to lock down Broodmother, preventing her from running into the treeline.
Additional:
* Overwhelming Odds's damage stacks with each enemy unit in its radius. If this hits Broodmother and a large number of spiders it can deal significant amounts of damage.
* Moment of Courage has a high chance to proc if Broodmother and all of her spiders are attacking her.
* Duel can keep Broodmother in place long enough for Legion's team to kill her.

* Sleight of Fist keeps Ember Spirit invulnerable until he hits every unit in its area of effect allowing him to stall for large amounts of time against Broodmother and her large amounts of spiderlings, or potentially damaging them enough if equipped with an item to improve wave clearing such as Battle Fury or Maelstrom to prevent her pushes entirely.
* Flame Guard will damage any of Broodmother's spiders in an area, deterring her from attempting to kill him. It can also be used during Sleight of Fist to amplify damage done.
* Fire Remnant allows Ember Spirit an escape from Broodmother that is unaffected by her Incapacitating Bite.

* Spiderlings are a good source of souls for Necromastery and can be quickly killed with Shadowraze.
* Shadow Fiend is a natural Black King Bar carrier, protecting him from Incapacitating Bite.
* Requiem of Souls combined with Eul's Scepter of Divinity can potentially kill Broodmother before she gets a Black King Bar

* Tiny can quickly clear Spiderlings with his active abilities and cleave.

* Kunkka's entire kit is great for taking out multiple units at once.
* Tidebringer's cleave will split through a wave of spiderlings.
* X Marks the Spot is great for dragging Broodmother back out of her web for Kunkka's team to set up on her.
* Torrent and Ghostship will demolish any spiderlings within the radius.
Additional:
* X Marks the Spot prevents Broodmother from escaping.
* Tidebringer can clear Broodmother's spiders if they get in range.

* Huskar's huge damage output and attack speed can get rid of Undying and Tombstone quickly.

* Mass summoning heroes: Broodmother, Nature's Prophet and Enigma are all able to mass-summon units, which Puck is able to clear with Illusory Orb and Waning Rift instantly, due to their summons having low health.

* High health heroes like Pudge and Undying gain strength by using abilities. Focusing them with Spirit Siphon can let you heal more health and deal more damage to them.

* Mirana can destroy Tombstone, and evade zombies using Leap and Moonlight Shadow's invisibility.

* In general, melee heroes without blink mechanisms or spell immunity will have a hard time positioning against Pit of Malice: Sven, Tiny, Wraith King, Dragon Knight, Meepo, Doom, Bounty Hunter, Dark Seer, Undying, Alchemist, Legion Commander.

* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: Broodmother, Enigma, Nature's Prophet.

* Broodmother's spiderlings and spiderites do almost nothing against Dragon Knight.

Additional:
* Breathe Fire will clear Broodmother's spiderites while significantly damaging her spiderlings and decreasing their damage output.
* Dragon Blood's added armor and regen mitigates the damage done by Broodmother and her spiders.
* Elder Dragon Form at level 2 and above applies splash damage to Dragon Knight's auto attacks.

* Heroes with area of effect abilities that increase in power based on the number of units struck: Legion Commander, Grimstroke.

Additional:
* Stroke of Fate can deal heavy damage to Broodmother and her spiders, and with enough spiders it can kill her instantly.
* Phantom's Embrace provides vision on Broodmother when she's fleeing into the trees.

* Heroes with summons can find their summons eliminated easily by Lina, like Broodmother, Nature's Prophet, and Chen.

Additional:
* Light Strike Array in combination with Dragon Slave can easily clear Broodmother's spiders.
* Laguna Blade offers extensive damage that can kill Broodmother early on or before she is able to use Insatiable Hunger in attempts to salvage a fight.