* Acid Spray and Greevil's Greed will quickly destroy pushes with treants.

* Clockwerk's long range initiation and catch makes it incredibly difficult for Nature's Prophet to split push and show on the map alone.

* Power Cogs greatly limits Sven's positioning, potentially wasting the duration of Black King Bar in a teamfight.
* Battery Assault makes it hard for Sven to fight Clockwerk in his Power Cogs.
* Clockwerk's Blade Mail forces Sven to avoid attacking while inside Power Cogs, effectively rendering him useless for a few seconds.

* Chemical Rage out-heals Doom to a large degree throughout all stages of the game. Should Alchemist be chemically enraged before being Doomed, Alchemist can become a difficult target to effectively lockdown and kill, thanks to the health regeneration and movement speed bonuses granted by his ultimate.
* Alchemist is an ineffective target for Doom. Alchemist isn't totally reliant on his skills to be effective during a teamfight, due to the right-click nature of the hero.

* Magnus has very mediocre damage against Alchemist, because he can survive the stun duration of Reverse Polarity with Chemical Rage.

* Meat Hooking a Clockwerk can backfire for Pudge, as Battery Assault and Blade Mail will hurt Pudge more than he hurts Clockwerk.

* Battery Assault's mini-stuns can severely disrupt Legion Commander's attack animation when she enters a Duel, potentially saving Clockwerk (or his allies) and possibly even giving him an edge in securing a win himself.
* Power Cogs pushes Legion Commander away from Clockwerk's allies when she enters a Duel.

* Hookshot lets Clockwerk close the gap to Drow Ranger, disabling her Marksmanship bonus.
* Power Cogs and Battery Assault keep Drow Ranger from escaping.
* Power Cogs and Battery Assault also keep Drow Ranger close, nullifying Marksmanship.
Additional:
* Getting trapped in Power Cogs usually means the end for Drow Ranger.

* Battery Assault interrupts Earthshaker's long cast animations, preventing him from using any abilities apart from Echo Slam.
* Power Cogs often separate the battlefield so that both enemies and allies are unlikely to cluster.
* Rocket Flare allows Clockwerk to scout Earthshaker before a fight starts and potentially cancel his Blink Dagger.
* Hookshot enables Clockwerk to catch Earthshaker before he gets a chance to initiate a fight.
Additional:
* Battery Assault will continuously interrupt Earthshaker's long cast animations.
* Power Cogs can also trap Earthshaker after he initiates.

* Clockwerk is also the least optimal target for Sniper to attack in a teamfight, although more experienced players will rarely make this mistake.
* With no mobility or disable skills, getting trapped in Power Cogs is a death sentence for Sniper.
Additional:
* Clockwerk can easily close the distance to Sniper using Hookshot and trap him with Power Cogs.
* Even though Sniper is a natural Hurricane Pike carrier, Sniper's low health usually means Clockwerk can finish him off with Battery Assault and Rocket Flare.

* Battery Assault, Power Cogs, and Hookshot can interrupt Freezing Field, the latter two being able to go through invisibility should Crystal Maiden use Glimmer Cape.
* Rocket Flare can be used to find Crystal Maiden should she try to hide in the trees to try to safely cast Freezing Field.
* Hookshot allows Clockwerk to easily close in on Crystal Maiden and kill her.

* Battery Assault's continuous mini-stun makes it hard for Elder Titan to cast his spells due to his poor cast animation.
* Elder Titan's channelling with Echo Stomp makes a good setup for Hookshot if timed correctly.

* Chemical Rage will take down Tombstone in no time.
Additional:
* With Greevil's Greed, Alchemist can farm Tombstone zombies and gain a significant gold advantage.

* Clockwerk can use Power Cogs to repel Spirit Breaker when he charges in with Charge of Darkness.
* Spirit Breaker's slow 0.6 second attack animation attacks do little damage against Clockwerk. It can also constantly be interrupted by Battery Assault.
* Nether Strike's 1.2 second charge time gives Clockwerk plenty of time to activate Blade Mail and for Battery Assault to cancel it.
Additional:
* Battery Assault will continuously prevent Spirit Breaker from using Nether Strike, Charge of Darkness and even right clicking because of his long attack animation.
* Charge of Darkness can be cancelled by a correctly timed Hookshot.
* Should Clockwerk or his allies be targeted by Charge of Darkness, he can stop it by casting Power Cogs in Spirit Breaker's path or around the target.

* Power Cogs prevent Windranger from fleeing with Windrun.
* Battery Assault repeatedly interrupts Focus Fire, disrupting Windranger's damage output.

* Alchemist can easily farm Spiderlings with Acid Spray and Greevil's Greed.
* Alchemist's Chemical Rage nullifies Broodmother's Insatiable Hunger
Additional:
* Greevil's Greed makes Broodmother’s spiderlings far more valuable to Alchemist making it important that he does farm them as opposed to other heroes where the spider's bounties are negligible.
* Acid Spray makes it difficult to attack Alchemist in lane without losing some spiderlings to the damage over time, potentially giving him farm he wouldn't have otherwise.

* Rocket Flare can find Tinker if he blinks into the treeline, and Hookshot will prevent him from teleporting out.
* Battery Assault makes Tinker unable to Rearm by stunning him repeatedly.
Additional:
* Clockwerk can easily catch a split pushing Tinker with his Hookshot and prevent him from escaping with Power Cogs and Battery Assault.
* He can find a Tinker hiding in trees with his Rocket Flare.
* Clockwerk usually buys a Blade Mail, which does lots of damage to Tinker if he gets hit by his abilities (especially March of the Machines).

* Black Hole requires channelling, making it easy to be interrupted with Hookshot.
* Enigma lacks mobility without a Blink Dagger and also is squishy, making him fall easily when ganked by Clockwerk.
Additional:
* Hookshot's stun pierces through spell immunity and Enigma's channeling can be easily cancelled from a safe distance, assuming none of his allies are in the way.
* Enigma lacks mobility without Blink Dagger or Force Staff. Clockwerk can stay atop Enigma using Battery Assault and isolate him with Power Cogs, and potentially track him down with Rocket Flare.

* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as Batrider, Beastmaster, Pudge and Clockwerk.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Heroes with long cast animations can be continuously interrupted by Battery Assault: Centaur Warrunner, Jakiro, Leshrac, Naga Siren, Underlord.

Additional:
* Battery Assault easily interrupts Centaur Warrunner due to his poor cast animation.
* Power Cogs can negate Stampede.

* Power Cogs pushes Monkey King out of Wukong's Command, ending his ultimate.
* Rocket Flare allows Clockwerk to scout Monkey King in the trees, and chase him with Hookshot.
Additional:
* Rocket Flare ends Mischief, and reveals Monkey King on the treetops.
* Hookshot can catch Monkey King when he retreats to the treeline.

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

* Heroes with long cast animations can be continuously interrupted by Battery Assault: Centaur Warrunner, Jakiro, Leshrac, Naga Siren, Underlord.

Additional:
* Battery Assault prevents Jakiro from casting spells as all his spells have very long cast times.
* Jakiro is also an easy target for Clockwerk's Hookshot + Power Cogs combo, as he has little mobility and no escape.
* Alternatively, if the enemy Clockwerk traps one of his own allies or Jakiro's allies in the cogs, it gives Jakiro an ideal setup to punish Clockwerk and his ally or to save Jakiro's ally, respectively.

* Heroes with long cast animations can be continuously interrupted by Battery Assault: Centaur Warrunner, Jakiro, Leshrac, Naga Siren, Underlord.

Additional:
* Clockwerk naturally builds Blade Mail, reflecting Leshrac's high magic damage output back at him.
* Power Cogs will prevent Leshrac from reaching Clockwerk's team and dealing large AOE damage to them.
* Power Cogs will also keep Leshrac close, wasting his Diabolic Edict on just Clockwerk.
* Battery Assault interrupts Leshrac's long cast times of Split Earth and Lightning Storm.

* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.

* Heroes with long cast animations can be continuously interrupted by Battery Assault: Centaur Warrunner, Jakiro, Leshrac, Naga Siren, Underlord.

* Pugna's squishiness and lack of mobility make him easy prey for a Hookshot initiation.
* Clockwerk's high health, low mana costs, and lack of reliance on Blink Dagger make Nether Ward ineffective.
* Battery Assault shuts down Aghanim's Scepter upgraded Life Drain, as the repeated ministuns prevent Pugna from channeling for an extended length of time.
Additional:
* Clockwerk loves to Hookshot low health, immobile targets like Pugna.
* Pugna's Life Drain gets immediately and repeatedly (if an Aghanim's Scepter was purchased) cancelled due to Battery Assault, especially if Pugna is trapped inside Power Cogs.
* Clockwerk also loves to build Blade Mail, which will deal more damage to Pugna than Clockwork due to Pugna's low health pool.
* Finally, both Hookshot and Rocket Flare can allow him to finish off Pugna out of range of his Nether Ward.

* Chemical Rage kills Phoenix very quickly in Supernova.

* Heroes with long cast animations can be continuously interrupted by Battery Assault: Centaur Warrunner, Jakiro, Leshrac, Naga Siren, Underlord.

* Alchemist's Acid Spray can heavily damage Chen's creeps and disrupt his jungling.
* Alchemist builds items like Radiance and Battle Fury, allowing him to quickly clear Chen's creeps.
* Alchemist's Greevil's Greed will grant him more bonus gold as he kills Chen's creeps.

* Chemical Rage negates almost all damage from Burning Spears.
Additional:
* Chemical Rage mitigates damage from Burning Spear.