* Dark Seer can take great advantage of Divided We Stand by putting an Ion Shell on a clone in order to harass them effectively.
* Vacuum can take a single Meepo and disable them for him and his teammates to take out.

* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.

* Dark Seer's Vacuum and Ion Shell allows him to clear the wave of Terrorblade's illusions.
* Wall of Replica can create stronger illusions of Terrorblade.
* If Dark Seer can use Vacuum to help teammates land their AoE skills, Terrorblade will be quickly killed before he even gets a chance to use Sunder.
Additional:
* Dark Seer's Vacuum and Ion Shell allows him to clear a wave of Terrorblade's illusions.
* Wall of Replica can create stronger illusions of Terrorblade.
* If Dark Seer can use Vacuum to help teammates land their AoE skills, Terrorblade will be quickly killed before he even gets a chance to use Sunder.

* Heroes that can stall pushes: Invoker, Keeper of the Light, Lina, Luna.

* Dark Seer's Vacuum and Ion Shell can clear a wave of Chen's Creeps effectively.

* Cold Snap can prevent Timbersaw from using both Timber Chain and Chakram due to the frequent stuns interrupting the lengthy cast animations, as well as stopping him mid-chain. This can negate Timbersaw's attempts to escape or dole out extra ability damage.
* Later in the game, Invoker's heavy magical and pure damage can be difficult to avoid, meaning Timbersaw's armor is less useful.

* Tornado dispels Guardian Angel from multiple targets.
* Guardian Angel is generally useless against Invoker as he primarily relies on magical damage.
* EMP depletes Omniknight's already small mana pool.
* Invoker's many disables keep Omniknight's team occupied until Guardian Angel times out.

* Quas-Exort Invoker can win the mid lane easily against Alchemist because Quas regeneration will nullify Acid Spray's damage over time and Exort damage bonus will allow Invoker to out last hit Alchemist.

* EMP allows Invoker to burn Medusa's mana to weaken Mana Shield.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
* EMP is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
* Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
* Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.

* Cold Snap allows Invoker to interrupt Charge of Darkness and Nether Strike.
* Tornado's long range can be used to cancel Charge of Darkness.
* Deafening Blast prevents Spirit Breaker from right clicking and thus proccing his Greater Bash.

* Venomancer is a low health hero and low range hero who is easy to harass with Ion Shell on a creep in the early game .
* Venomancer depends entirely on all his slows to keep distance or chase, but Surge ignores slows, so is nearly impossible to hunt or run away from Dark Seer or his surged teammates.

* Cold Embrace is the perfect setup for all his nukes - Chaos Meteor, EMP and especially global Sun Strike.

* Surge allows for Dark Seer and his allies to escape from Upheaval due to it ignoring any slow.

* His Forge Spirit can negate Flux.
* Provided he does a right combo with Chaos Meteor, Invoker can easily burst down Arc Warden (plus his clone if he spawns it.)
* An early Orchid Malevolence can shut down Arc Warden pretty hard, especially when Invoker has a good lane against him if he kills him early on.
* Deafening Blast and Ice Wall limit's Arc Wardens mobility and damage, crippling him greatly.

* Tornado allows Invoker to purge Necrophos's Ghost Shroud, nullifying any benefits he could get out of it
* EMP allows Invoker to burn Necrophos's mana, preventing him from using his abilities constantly

* Invoker can drain Wraith King's mana with EMP, preventing him from reincarnating unless Wraith King has his Aghanim's Shard.
* Even if Wraith King survives and reincarnates, Invoker still has an arsenal of spells to lockdown Wraith King, including an easily setup Ice Wall.
* Tornado applies an area dispel to clear skeletons.
Additional:
* EMP allows Invoker to burn Wraith King's mana to prevent Reincarnation from triggering (only until Wraith King gets his Aghanim's Shard).
* Ice Wall and Cold Snap are particularly crippling for Wraith King as they allow to kite him very effectively, preventing him from dealing melee attack damage.

* Quas Exort Invoker has high physical damage in the form of Cold Snap and Forged Spirits that allows him to trade hits with Huskar.
* Although Huskar can dispel Cold Snap with Life Break.
* Sun Strike deals pure damage and pierces spell immunity, and Huskar tends to drain his HP, making him a susceptible target.

* Living Armor can be destroyed quickly with Ion Shell.

* Dark Seer can pull together Spectre's illusions with Vacuum, and Wall of Replica creates an illusion of Spectre that deals massive damage.

* Heroes with naturally low mana can be easily shut down by EMP: Sven, Tiny, Wraith King, Omniknight

* Heroes with haste can negate Enchant's slow: Weaver, Dark Seer, Lycan, Centaur Warrunner.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Heroes with summons like Broodmother,Enigma, Invoker, Nature's Prophet, Lycan, Visage;or illusions, like Naga Siren, Phantom Lancer, Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity mines in the early game.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King.

* Ice Wall and Ghost Walk can be used to kite and escape from Viper.
* Chaos Meteor and Sun Strike deal heavy damage and can quickly bring Viper down.
* Cold Snap, Tornado, and Deafening Blast are powerful disables that reduce Viper's effectiveness.
* EMP burns Viper's limited mana pool, reducing his potential poison damage.
* Forge Spirits can melt Viper's armor and reduce his durability.

* Heroes who do not have nor rely on passive abilities make Nethertoxin much less effective: Clinkz, Pugna, Nature's Prophet, Dark Seer, Lycan, Tusk

* Heroes with long animations can be frequently interrupted with Cold Snap: Earthshaker, Monkey King, Shadow Fiend Lina

* Heroes with long animations can be frequently interrupted with Cold Snap: Earthshaker, Monkey King, Shadow Fiend Lina

* Invoker's EMP is extremely effective against Earthshaker due to his low natural mana.

* Heroes with naturally low mana can be easily shut down by EMP: Sven, Tiny, Wraith King, Omniknight

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* Heroes that rely on illusions will suffer against Ion Shell, which kills them very quickly: Phantom Lancer, Chaos Knight, Naga Siren, Meepo.
* Heroes that rely on illusions typically spawn very strong illusions inside your Wall of Replica that you should use against them or their team.

* The haste provided by Dark Seer's Surge or a {Rune:Haste} renders your slows ineffective.

* Invoker's multiple spells can lock down Undying and disable him from doing much.

* Dark Seer can increase the movement speed of allies with Surge, breaking Static Link.

* Some heroes with extreme range, like Zeus, Invoker or Clockwerk, can snipe your allies from anywhere after your Grave has expired.

* Heroes that can keep Marci for a long time in one place so she can't pursue her targets, like Bane, Lion, Shadow Shaman, Invoker, Disruptor and Kunkka.

* Heroes that rely on illusions will suffer against Ion Shell, which kills them very quickly: Phantom Lancer, Chaos Knight, Naga Siren, Meepo.
* Heroes that rely on illusions typically spawn very strong illusions inside your Wall of Replica that you should use against them or their team.

* Heroes that rely on illusions will suffer against Ion Shell, which kills them very quickly: Phantom Lancer, Chaos Knight, Naga Siren, Meepo.
* Heroes that rely on illusions typically spawn very strong illusions inside your Wall of Replica that you should use against them or their team.

* Invoker's spells will disable and destroy Legion Commander while she's locked in a Duel.

* Ion Shell is a very powerful weapon against Broodmother's Spiderlings and makes her laning much harder.
Additional:
* Ion Shell zones out Broodmother in the laning phase, and can kill her spiderlings if used on one Spiderling in a group.
* Vacuum can pull Broodmother out of the treeline.

* Certain heroes can mess up with Pangolier's positioning and timing (especially if he intends to use Rolling Thunder during combat): Vengeful Spirit, Keeper of the Light, Huskar, Dark Seer

* Heroes with long animations can be frequently interrupted with Cold Snap: Earthshaker, Monkey King, Shadow Fiend Lina

* Invoker's arsenal of magical spells are troublesome for Sniper who has low HP and high armor, which does not benefit him much against Invoker.
* Besides magical damage, he can be disarmed and repeatedly mini-stunned with Cold Snap, preventing him from reacting.
* Leveling Quas can allow Invoker to lane effectively against Sniper despite right-click harassment.

* Heroes with AoE abilities will hit Slark in Shadow Dance: Lina, Jakiro, Underlord, Leshrac, Dark Seer, Earthshaker, Timbersaw, Crystal Maiden

* Ion Shell destroys Refraction's protection stacks in short time.
* Surge ignores the massive slow from Psionic Trap.

* Heroes that can gain vision over trees to catch Tinker: Invoker, Shadow Demon, Batrider

Additional:
* Tinker is relatively helpless against Invoker, as his Rearm and Boots of Travel can be easily interrupted by Invoker's long range disables, even if he blinks away.