* Firestorm's percentage damage can quickly demolish the Spirit Bear's high HP
* Pit of Malice will allow allies to easily kite Lone Druid due to his low mobility

* In general, melee heroes without blink mechanisms or spell immunity will have a hard time positioning against Pit of Malice: Sven, Tiny, Wraith King, Dragon Knight, Meepo, Doom, Bounty Hunter, Dark Seer, Undying, Alchemist, Legion Commander.

* Laser blinds Lone Druid, making his attacks miss. Furthermore, a Tinker with Aghanim's Scepter is sure to blind both Lone Druid and his bear, negating his ability to root or deal physical damage.

* Lone Druid during True Form and the Spirit bear has high HP, meaning Spirit Siphon can be very effective against them since they deal percentage damage

* Arcane Orb deals heavy damage to both Lone Druid and the Spirit Bear.
* Astral Imprisonment can prevent the Spirit Bear from attacking, which is Lone Druid's main damage output.
* Sanity's Eclipse deals heavy damage to Lone Druid.

* Fortune's End can dispel Ion Shell, which cripples Dark Seer economy since it's his most efficient tool for farming.
* Fortune's End can dispel Surge, effectively slowing his movement speed making him vulnerable to ganks or skirmishes.
Additional:
* Fortune's End dispels Ion Shell and Surge, making any gank attempt on Dark Seer in the laning phase likely to succeed.
* Fate's Edict prevents all magical damage that comes from Dark Seer's abilities.
* Fortune's End dispels Ion Shell on creeps, which Dark Seer relies on to farm and zone.

* Ghost Shroud can be use both offensively to slow Lone Druid or Defensively to prevent Lone Druid and The Spirit Bear from attacking him.
* Heartstopper aura burns the Spirit bear High HP over time. Additionally, it can deal decent damage to Lone Druid during his True Form.

* Lone druid's bear attacks on Phoenix's Supernova Egg don't increase the hit count. Given that Lone Druid's main hero often doesn't have much farm, the Supernova Egg is less likely to get killed.

* Brewmaster can make the Spirit Bear a much smaller threat with Cinder Brew.
* Cyclone removes the bear from a fight so that his team can easily focus on the hero.
* While most heroes would be worn down by a Spirit Bear Radiance in the time it takes to kill Lone Druid, Brewmaster is protected in Primal Split.

* Cold Embrace can protect allies from Lone Druid and the Spirit bear, who mainly deal physical damage
* Winter's Curse can turn Lone Druid and the Spirit Bear against his teammates.

* A Sniper who is somewhat competent at positioning is hardly going to be affected by any of Dark Seer's spells thanks to Take Aim.
* However, an illusion of Sniper made with Wall of Replica is extremely powerful, and hard to deal with.

* Dark Seer's strength lies in his high-mana cost skills. So Mana Break can be a great nuisance for him, since it can reduce his mana and prevent him from casting his spells.
* Mana Void can deal a lot of damage if Dark Seer spent a lot of mana on his abilities.

* Grimstroke's Soulbind will always reliably connect onto both of them if they are close together.

* Paralyzing Cask is likely to bounce between him and his bear every single time.
* Lone Druid's lack of mobility makes him vulnerable to Death Ward and Maledict.

* Flame Guard makes Dark Seer not deal any damage with his skills to Ember Spirit.

* Morphling can ignore Spirit Bear and shorten the distance to Lone Druid with Waveform.
* Morphling can use his nukes to burst Lone Druid down, provided he is not rooted/disabled by Spirit Bear beforehand.

* Lone Druid and The Spirit Bear cannot burst down Bristleback due to Bristleback
* Bristleback can easily run to Lone Druid without any hesitation, with Viscous Nasal Goo to reduce armor and slow the Spirit Bear or Lone Druid and Quill Spray can deal damage to both Lone Druid and the Spirit Bear at the same time

* Blur allows Phantom Assassin to escape from Lone Druid and the spirit bear. Additionally, it provides evasion which effectively reduce the damage output from the Spirit Bear and reduce the chances to root her, forcing him to invest in Monkey King Bar
* At late game, Phantom Assassin will out carry Lone Druid.

* X Marks the Spot prevents Dark Seer or his allies from escaping with Surge.

* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom

* Pugna: Decrepify prevent the Spirit bear from attacking or protect allies from it.

* A well-timed use of The Swarm provides vision over heroes with high mobility: Anti-Mage, Arc Warden, Dark Seer.

* Heroes with fast movement abilities will suffer huge damage when afflicted by Rupture: Spirit Breaker, Earth Spirit, Dark Seer.

Additional:
* Rupture can deal a lot of damage to either a surged Dark Seer or his allies and prevent the target to get into position.

* In general, heroes who are melee with no way to fight back can be very easily poked by Monkey King to gain his Jingu Mastery stacks: Dark Seer, Riki, Rubick.

* Dark Seer relies on Surge for most of his mobility, so he's not very vulnerable to slows, but much more to root effects and walls or pseudo-walls such as Disruptor's Kinetic Field or Slark's Pounce.

* Timbersaw: Lone Druid will have a hard time dealing with Timbersaw due to his tankiness and high Armor from Reactive Armor

* Riki: Smoke Screen can prevent Lone Druid from using True Form and Savage Roar, additionally it cause the spirit bear to miss on attacks which reduce the chances of getting rooted from it, with diffusal Blade, he can keep Lone Druid or the Spirit Bear inside the Smoke.

* Dark Seer's only disable is Vacuum. Though he starts off with high armor and health, he'll eventually have a hard time dealing with high mobility heroes such as Weaver or Queen of Pain.

* Unless Lone Druid purchases a Black King Bar for his Spirit Bear, Ensnare will easily kite the Bear.
* Song of the Siren allows Naga Siren and her team to completely bypass the Spirit Bear and hunt for the Druid himself when starting a fight.
* Lone Druid's lack of innate AoE capabilities mean that Naga Siren's illusions have no problem against him.

* Reality Rift lets Chaos Knight bypass the Spirit Bear and jump onto Lone Druid.
* The Spirit Bear's lack of scaling means it dies quickly to Chaos Knight during the late-game.

* Lone Druid and his Spirit Bear lack mobility, and are easy overwhelmed after being slowed by Diffusal Blade.
* Savage Roar is useless since Phantom Lancer can return to fight him again with his Phantom Rush.

* Chain Frost will bounce between Lone Druid and his bear, forcing them to separate or suffer high amounts of damage.
Additional:
* Chain Frost can deliver high amounts of damage to Lone itself and his bear if they do not separate fast from each other.

* The constant dispel from Demonic Purge will make any attempt to save the victim or himself by Surge become futile. For what it's worth, Demonic Purge will also dispel Ion Shell.