* Because Warlock's abilities are all active abilities, Silencer can make his impact minimal.
* Arcane Curse prevents Warlock from using his abilities without taking 56/84/112/140 damage, and slowed by 9%/12%/15%/18%.
* Last Word can prevent Warlock from casting his combo.
* Global Silence can nullify Warlock's impact in fights and prevent him from getting any spells off.

* Surge allows for Dark Seer and his allies to escape from Upheaval due to it ignoring any slow.

* Dark Seer's Vacuum and Ion Shell can clear a wave of Chen's Creeps effectively.

* Silencer burns easily through her effective hp from Mana Shield, by taking away her int.
* Arcane Curse punishes her repeatedly casting Mystic Snake to keep her mana pool high. Can force her to use Manta Style before he has cast Global Silence and Medusa usually does not want to build Black King Bar.

* Arcane Curse discourages Lina from using her abilities, preventing her from building up Fiery Soul stacks.
* Last Word and Global Silence are great against Lina for the same reason, as well as interrupting her combos and preventing her from casting spells.

* Dark Seer can take great advantage of Divided We Stand by putting an Ion Shell on a clone in order to harass them effectively.
* Vacuum can take a single Meepo and disable them for him and his teammates to take out.

* Global Silence stops Snapfire's Mortimer Kisses.
* Last Word can prevent Snapfire from casting additional spells.

* Arcane Curse stacks every time Bristleback uses an ability, forcing him to stop spamming his abilities, or take heavy health degeneration.
* Glaives of Wisdom steals intelligence both permanently and temporarily, causing mana issues for Bristleback .
* Last Word and Global Silence stops Bristleback from using his abilities altogether.
Additional:
* Bristleback will not be able to cast Viscous Nasal Goo or Quill Spray while silenced, effectively blocking a major part of the hero's damage and preventing Warpath charges from stacking.
* Arcane Curse slows Bristleback down and lasts longer the more abilities he uses. On the other hand, if he doesn't use any abilitiess, he will begin to lose Warpath charges.

* Like any hero with a channeled spell, Last Word is a counter to it.
* Global Silence goes through spell immunity and prevents Witch Doctor from casting his spells.

* While many of Silencer's spells are a great steal for Rubick, Silencer effectively neuters Rubick's excellent counter-initiation potential thanks to Global Silence.
* Rubick's relatively low intelligence for such a heavy caster means that losing Intelligence to Intelligence Steal will make your mana pool even smaller.

* Arcane Curse punishes Grimstroke for spamming Stroke of Fate.
* Global Silence takes Grimstroke out of team fights entirely.

* Silencer's Global Silence will render Zeus useless for 6 seconds in a team fight.
* Arcane Curse will punish Zeus for casting spells, which can cause continuous damage to him should he continue to cast spells.
* Last Word can silence Zeus and prevent him from spamming his spells.
* Silencer often builds Orchid Malevolence (or Bloodthorn) which can be used on spell casters like Zeus, forcing him to invest in a Linken's Sphere.
Additional:
* Zeus' main source of damage is his low cooldown, high damage spells - meaning Last Word and Global Silence will pretty much take him out of the game for the duration.
* Zeus likes to spam his abilities, which makes him vulnerable to Arcane Curse.
* If Zeus dies near Silencer, he will lose intelligence, reducing his mana pool, mana regen and attack damage. Furthermore, if the game is long and Zeus dies often, the intelligence losses will also reduce his spell damage.

* A well-timed Global Silence prevents Dazzle from saving allies with Shallow Grave or Shadow Wave. Items that could dispel the silence are expensive, and difficult for Dazzle to farm from a support role.
* Arcane Curse and Last Word cause long damage over time, which may outlast Shallow Grave.

* Dark Seer's Vacuum and Ion Shell allows him to clear a wave of Terrorblade's illusions.
* Wall of Replica can create stronger illusions of Terrorblade.
* If Dark Seer can use Vacuum to help teammates land their AoE skills, Terrorblade will be quickly killed before he even gets a chance to use Sunder.
Additional:
* Dark Seer's Vacuum and Ion Shell allows him to clear the wave of Terrorblade's illusions.
* Wall of Replica can create stronger illusions of Terrorblade.
* If Dark Seer can use Vacuum to help teammates land their AoE skills, Terrorblade will be quickly killed before he even gets a chance to use Sunder.

* Arcane Curse deals repeated stacks of damage to Timbersaw because he relies on constantly using his abilities.
* Glaives of Wisdom deals pure damage and when cast manually, nearby creeps will not attack silencer, making it an effective harassment tool.
* Although Last Word takes a while to trigger, it will break Timbersaw's ability combo and can be used to silence him.
* Global Silence will silence Timberaw no matter where he is on the map. This can be used to help allies get a kill on him, or prevent Timbersaw from killing someone.
Additional:
* Timbersaw is heavily reliant on his abilities for damage and escape, allowing Silencer to effectively disable him and make him useless in both team fights and 1v1 scenarios.

* Invoker is heavily dependent on his spells, making him useless during Global Silence, as well as interrupting Invoker during his combo.
* Arcane Curse is particularly deadly, because Invoker will continuously lose health if he keeps invoking and casting new spells.
* Last Word will silence Invoker when he casts Invoke, interrupting his combo.

* Silencer's Intelligence Steal can reduce Storm Spirit's damage output if he gets some kills on laning phase.
* Last Word and Global Silence will make Storm Spirit an easy target.
* Global Silence can be used to block Storm Spirit from connecting abilities after a Ball Lightning on his targets.

* Arcane Curse can effectively discourage Undying from casting his spammable abilities in a team fight, as Undying will have to suffer more damage and the slow due to the penalty duration of Arcane Curse.
* Last Word and Global Silence are able to silence Undying for up to 6 seconds, preventing Undying from gaining strength and healing his ally or himself.

* As Tinker relies heavily on his spells to be effective, Last Word and Global Silence will render him largely useless.
* Arcane Curse effectively prevents Tinker from casting spells during its duration, as he will otherwise suffer heavy damage.
* Glaives of Wisdom deal pure damage, which make quick work of fragile heroes like Tinker.
Additional:
* Silencer can stop Rearm, preventing Tinker from spamming his abilities/items or escaping.

* Venomancer is a low health hero and low range distance attack hero easily to harass putting Ion Shell in a distance creep enemy in early game .
* Venomancer depends entirely on all his slows poison skills to keep distance or chasing enemy heroes, but Surge ignores slows, so is nearly impossible hunt or run away of Dark Seer or his surged teammates.

* Crystal Maiden is squishy, is heavily spell reliant, has low base Intelligence, and is naturally slow, making her an ideal target for Silencer
* Crystal Maiden's Freezing Field has a similar cooldown to Global Silence, therefore, Freezing Field can almost always be canceled to ruin aggressive Crystal Maiden initiations.

* Arcane Curse punishes Necrophos if tries to spam Death Pulse, increasing the duration of the slow and damage taken over time.
* Last Word heavily damages Necrophos and also silence him for a lenghty duration.
* Glaives of Wisdom will reduce temporarily Necrophos intelligence on each hit dealing hindering his ability to spam Death Pulse, also reducing his attack damage and mana pool; dealing increasing amounts of phisical and pure damage each time. Silencer will permanently steal Necrophos intelligence if killed by him or dies nears him.
* Global Silence turns Necrophos almost useless for a long time, allowing your team to easily dispatch him, since he heavily relies on his spells to survive.

* Global Silence takes Omniknight out of the fight completely.
* Glaives of Wisdom are a great harass vs Omniknight during the laning stages of the game, since it doesn't aggro creeps & ignores his high base armor. It deals pure damage, which means it can also go through Guardian Angel.
* Silencer's intelligence steal can also cause Omniknight to falter in the early phases as it reduces his ability to use his spells.

* Silencer will most likely disrupt an initiation with his ultimate, Global Silence, prevent escape with his Last Word, and if Phoenix happens to die to him (or near him) enough times, he would sap enough of Phoenix's much needed Intelligence to make him a stronger foe and Phoenix with less mana than it already had.

* Silencer's Last Word and Global Silence prevents Jakiro from casting any spell.
* A carry Silencer can easily take down a support Jakiro with his Glaives of Wisdom.

* Pugna is very reliant on his abilities for damage. (Just be careful around the Nether Ward)

* Last Word and Arcane Curse have the range to hit Dark Willow beyond Bramble Maze.
* Global Silence renders Dark Willow useless in teamfights.

* Both Arcane Curse and Last Word punishes casters with spammable spells such as Sand King.
* As a strength caster, Intelligence Steal reduces Sand King's mana pool even more.
* Global Silence silences Sand King, effectively reducing Sand King's initiation and counter-initiation potential. It can also interrupt channeling of Epicenter.

* Silencer's intelligence steal will heavily reduce Outworld Destroyer's damage output, if Outworld Destroyer dies a lot near/to Silencer.
* Global Silence and Last Words will render Outworld Destroyer helpless unless he has dispelling item/ally.
Additional:
* Silencer's Intelligence Steal will heavily reduce Outworld Devourer's damage output, particularly from Sanity's Eclipse.
* Last Word and Global Silence will take Outworld Devourer out of the fight unless he has built Black King Bar.

* Living Armor can be destroyed quickly with Ion Shell.

* Generally strong against every spellcaster, Puck fully relies on their skill set and is barely a threat when silenced.
* Arcane Curse disables Blink Dagger for quite some time, and is also effective against Puck as he tend to use his spells a lot.
* Glaives of Wisdom can do a lot of damage against Puck due to Puck's low agility gain and armor.
* Last Word can prevent Puck from getting his full combo off, limiting his effectiveness in team fights or ganks.
* Global Silence can take Puck out of fights entirely.

* Silencer can easily ruin Enigma's initiation, as Global Silence cancels Black Hole, even through Black King Bar and Linken's Sphere.
Additional:
* Last Word can be cast from a long range to prevent Enigma's potential initiation.
* Global Silence can interrupt Enigma's Black Hole channeling through Black King Bar and Linken's Sphere.

* Heroes with haste can negate Enchant's slow: Weaver, Dark Seer, Lycan, Centaur Warrunner.

* Dark Seer can pull together Spectre's illusions with Vacuum, and Wall of Replica creates an illusion of Spectre that deals massive damage.

* Heroes with silencing abilities that are not blocked by Linken's Sphere, like Puck's Waning Rift, Death Prophet's Silence or Silencer's Global Silence.

* In general, heroes such as Lion, Silencer, Skywrath Mage, Sven, Ogre Magi and others with reliable disables are crucial to killing Techies before they can suicide.

* The haste provided by Dark Seer's Surge or a {Rune:Haste} renders your slows ineffective.

* Certain heroes can mess up with Pangolier's positioning and timing (especially if he intends to use Rolling Thunder during combat): Vengeful Spirit, Keeper of the Light, Huskar, Dark Seer

* Silencer's Global Silence and Doom's Doom makes Earthshaker temporarily useless.

* Lion is extremely dependent on his abilities. Silences like Silencer's Last Word, magic resistance like Oracle's Fate's Edict, and dispels like Legion Commander's Press the Attack all make his abilities less effective.

* Heroes with silence such as Riki, Silencer, or Night Stalker prevents Skywrath Mage from using his spells.

* Heroes that rely on illusions will suffer against Ion Shell, which kills them very quickly: Phantom Lancer, Chaos Knight, Naga Siren, Meepo.
* Heroes that rely on illusions typically spawn very strong illusions inside your Wall of Replica that you should use against them or their team.

* Windranger heavily relies on her abilities for any form of tactical advantage and damage. A well timed silence will make her useless: Puck,Silencer, Death Prophet, Skywrath Mage, Drow Ranger, Earth Spirit, Grimstroke.

Additional:
* Silencer's abilities hamper Windranger's effectiveness in battle, preventing her from comboing abilities and escaping using Windrun.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* With 4 active abilities, Shadow Shaman is weak against silencing foes such as silencer, Drow Ranger and Death Prophet.

* Heroes that have long silences, such as Night Stalker and Silencer, will prevent Abaddon from saving his allies effectively and disable the active component of Borrowed Time.

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* Dark Seer can increase the movement speed of allies with Surge, breaking Static Link.

* Ion Shell destroys Refraction's protection stacks in short time.
* Surge ignores the massive slow from Psionic Trap.

* Kunkka relies on his powerful AOE spells to turn the tides of teamfights. He cannot use them while silenced.
* Last Word can mess up Kunkka's ability synergy, silencing him in the middle of his strong combo.
* Global Silence can disable Kunkka's spell casting from anywhere on the map, even if Kunkka is spell immune at the time.

* Global Silence and Last Word can prevent Ember Spirit from casting Activate Fire Remnant to escape.
* Glaives of Wisdom also provide high pure damage that is not negated by Flame Guard.
* Arcane Curse is also a potent harassing tool in the laning stage as its cooldown is lower than Flame Guard's.

* Shadow Demon's main source of damage is his low cooldown, high damage spells - meaning Last Word and Global Silence will pretty much take him out of the game for the duration.
* Shadow Demon likes to spam his abilities, which makes him vulnerable to Arcane Curse.
* If Shadow Demon dies near Silencer, he will lose intelligence, reducing his mana pool, mana regen and attack damage. Furthermore, if the game is long and Shadow Demon dies often, the intelligence losses will also reduce his spell damage.

* Basically, Heroes that heavily rely on abilities for damage or escape, such as Queen of Pain and Storm Spirit.

* Heroes who do not have nor rely on passive abilities make Nethertoxin much less effective: Clinkz, Pugna, Nature's Prophet, Dark Seer, Lycan, Tusk

* Heroes with silences : Bloodseeker, Riki, Silencer.

* Heroes with pure damage can kill Huskar when he inevitably gets low on health: Outworld Destroyer, Silencer.

* Silences and other types of lockdown that prevent Weaver from using his spells: Silencer, Riki, Lion, Legion Commander, Shadow Shaman, Bane.

* Ion Shell zones out Broodmother in the laning phase, and can kill her spiderlings if used on one Spiderling in a group.
* Vacuum can pull Broodmother out of the treeline.
Additional:
* Ion Shell is a very powerful weapon against Broodmother's Spiderlings and makes her laning much harder.