* Nature's Prophet treants can be cleared by Ignite or Multicast Hand of Midas
* Fireblast and Unrefined Fireblast prevents Nature's Prophet from using Teleportation.

* Doom can eats Nature's Prophet's treants with Devour and gains lots of gold.
* Doom can buy Radiance or use his Scorched Earth to quickly wipe out a swarm of Treants.
* Doom and a ministun from Infernal Blade's prevents Nature's Prophet from escaping with Sprout and Teleportation.

* Doom is effective against every hero, and Void Spirit is no exception. Being unable to cast spells or items during fights for 16 seconds nullifies his impact entirely.
* Doom has a very versatile build and can consume creeps which has abilities that can stun or provide additional magic resistance.
* Doom's high strength gain and versatility in items can be effective against Void Spirit's magical damage.

* Side lanes with disables will greatly reduce the likeliness Void Spirit will be willing to rotate: Sven, Tiny, Wraith King, Ogre Magi.

* Silencer's Global Silence and Doom's Doom makes Earthshaker temporarily useless.

* Ignite can prevent Earthshaker from escaping and/or initiating with Blink Dagger.
* Fireblast and Unrefined Fireblast may help prevent Earthshaker follow through with his combo after landing an Echo Slam.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Bristleback.
* Doom prevents Bristleback from casting his two low cooldown abilities, which then prevents him from utilizing Warpath.
* If Doom gets an Aghanim's Scepter, he can disable Bristleback and Warpath, taking away much of his durability and damage potential in team fights.
Additional:
* Infernal Blade deals scaling damage and is useful against high health targets such as Bristleback.
* Doom disables Bristleback's low cooldown abilities, preventing him from triggering Warpath. With Aghanim's Scepter, it also breaks Bristleback's passive, rendering him more vulnerable.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Timbersaw.
* Timbersaw is extremely reliant on his abilities to be effective during a team fight - both for mobility, damage and crowd control. Timbersaw offers very little impactful right-click damage, and thus Doom is particularly crippling against this hero.
* Additionally, when upgraded with Aghanim's Scepter, Doom breaks Reactive Armor, which effectively removes the durability which Timbersaw is commonly known for.
Additional:
* Doom shuts down Timbersaw completely, negating his mobility and preventing him from doing any damage. It also breaks Reactive Armor's passive bonuses from Aghanim's Scepter.
* Infernal Blade can stun Timbersaw several times in a fight, potentially interrupting Timber Chain. Also it's useful since Timbersaw has high HP due to the damage scales based on max HP.

* Doom prevents Storm Spirit from using all of his abilities and items, rendering Storm Spirit useless in a fight.

* The damage block instances of Refraction can be burned down with Ignite.
* Fire Shield effectively reduces the burst damage from a Meld-charged ambush from Templar Assassin, provided the spell is cast beforehand.

* Doom can stop Death Prophet from casting spells, which makes her useless during team fights if she didn't cast Exorcism before the fight. Furthermore, Doom can use Scorched Earth to chase after her.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Axe more than most normal attacks, negating some of his durability.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Axe.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom's naturally low attack speed makes Counter Helix less likely to proc, and his high base health allows him to take a few Helixes with no danger.
* Doom makes Axe less disruptive, preventing him from using his skills or items. With Aghanim's Scepter, Counter Helix is also disabled, making him effectively useless for a lengthy duration.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Axe.
* Doom has low attack speed because of his high Base-Attack-Time, poor agility gain and limited attack-speed granting items which are commonly built. This means Doom will trigger Counter Helix less often and thus is an unideal target for initiation.
* Doom has naturally high HP so it takes longer for Doom to be brought down to the killing threshold of Culling Blade.
* Axe is highly reliant on his abilities and items to be effective during a fight. Without the usage of Berserker's Call and Blink Dagger due to Doom, Axe offers very little in the way of damage, effectively removing him from a fight.

* Doom completely takes Invoker out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Additional:
* Doom is a good way to shut down Invoker, preventing from casting spells and using items for a lengthy time, thus forcing him to invest on Linken's Sphere.

* Ember Spirit cannot use his Activate Fire Remnant to escape while under effect from Doom.

* Doom has several disable abilities to choose from jungle creeps (e.g. War Stomp, Ensnare) to deal with Shadow Fiend who lacks escape abilities.
* When Doom combines creep abilities with Scorched Earth, Infernal Blade, and Doom, Shadow Fiend most likely will die as he cannot use Shadowraze and Requiem of Souls to protect himself, and also cannot even flee by using Shadow Blade or Blink Dagger.
* Although Shadow Fiend has a high physical damage output, Doom has a large health pool to survive it, meaning Doom's combo with high magical damage output will shutdown Shadow Fiend first.
* Doom usually buys Radiance to improve his damage, making his nuke combo more deadly to Shadow Fiend. The blind also prevents Shadow Fiend from landing his attacks often.

* Faceless Void relies on Time Walk for mobility and survivability but he can be prevented from utilizing it through Doom.
* Doom has a high cooldown duration for every ability except Infernal Blade, so he is not significantly affected by Time Dilation.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Spectre more than most normal attacks, negating some of her tankiness.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Spectre.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom makes Spectre less disruptive. Combined with Aghanim's Scepter, it will disable Spectre passive skills, reducing her potential in teamfights.
Additional:
* Infernal Blade's damage is calculated by percentage of max health. Since Spectre is usually tanky, it will hurt her more than most normal attacks.
* Doom can entirely disable Spectre from a teamfight. If upgraded with Aghanim's Scepter, it will disable her passive skills which is she relies on, crippling her.

* Doom disables the toggling of Rot and, if cast at the right time, may leave Pudge with a potentially lethal health drain.
* Doom's naturally high health, strength gain and damage output makes him a poor target for Pudge.
* The damage of Doom's Infernal Blade scales with the target's maximum health, which is particularly effective against Pudge due to his naturally high health and further health granted by stacks of Flesh Heap.
Additional:
* Infernal Blade deals high damage to Pudge due to his high strength grow with Flesh Heap.
* Using Doom with timing against Pudge who had just activated Rot would usually kill him.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Elder Titan. It also can interupt Echo Stomp if quick enough.
* Doom has very low base armor and naturally high HP, so he isn't significantly affected by Natural Order.

* Doom alone can easily pick off Crystal Maiden since she is fairly fragile, even with using only basic attacks, Infernal Blade, and Scorched Earth.
* Doom prevents her from using any abilities in a fight, making her impact negligible.
* Devour allows Doom to acquire a stun, allowing him to cancel Freezing Field without having to use Doom.

* Scorched Earth deals damage to Clinkz during Skeleton Walk.
* Doom shuts down Clinkz entirely, as it prevents him from casting any of his spells and contributing a large amount of damage in teamfights.

* Doom pierces spell immunity and can prevent Enigma from casting any spells or using items until the duration of the spell depletes, as well as cancelling a Black Hole. This can however, be blocked by a Linken's Sphere, a common item on Enigma.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Tidehunter.
* Doom prevents Tidehunter from casting his Gush, Anchor Smash and Ravage, making him useless in team fights.
* If Doom gets an Aghanim's Scepter, he can also disable Kraken Shell, reducing his survivability.

* Tinker is heavily reliant on casting his spells and Doom can disable all of his abilities and items. An Aghanim's Scepter only makes it harder for Tinker to survive.
Additional:
* Tinker is heavily dependent on active abilities and Doom prevents him from using any of them.

* Scorched Earth can be used to engage Visage while removing Gravekeeper's Cloak charges.
* Infernal Blade will deal tremendous amounts of damage over time due to Visage's high health pool.
* Doom completely nullifies Gravekeeper's Cloak and prevents Visage from casting spells.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Heroes with silences: Puck, Doom, Riki.

* Heroes that can cancel Charge of Darkness: Ogre Magi, Earthshaker, Lion .

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

* Heroes with abilities that break Berserker's Blood, lowering Huskar's attack speed and health regeneration: Doom, Shadow Demon, Viper.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Mars has no way to trade with Ogre Magi in the early game thanks to his high base health, resistance and Ignite.
* Once Ogre Magi gets level 2 he may also have Bloodlust, which makes him even harder to deal with in lane.
* Fireblast can be ridiculously strong later on in the game for controlling Mars.
* Spear of Mars, which is Mars' main source of damage in the early game, cannot guarantee kills early on Ogre Magi.

* A well-timed Fireblast with Multicast can prevent Weaver from escaping with Shukuchi and even Time Lapse.
* Ignite's high damage early on applies heavy pressure onto Weaver's very small health pool.
* However, the slow from Ignite is generally useless against Shukuchi, and Time Lapse dispels it if needed.

* Fireblast is a good tool to interrupt Io during its escapes through Tether.
* Ignite can be one of the few spells with enough total damage to out-trade the sustained healing Io provides for its fellow laner.
* However, picking other supports that focus less on the laning phase is generally a better choice against Io.

* Doom can completely shut down Dazzle through Doom, as it prevents him from casting his abilities and, by extension, gaining Bad Juju stacks.

* A well-timed Doom prevents Nyx Assassin escaping with Vendetta and does not allow him to disengage with Spiked Carapace.
* Doom's high HP easily shrug off Nyx Assassin's burst damage and fend him off.

* Doom makes Ursa less disruptive, and it cannot be dispelled with Enrage upgraded with Aghanim's Scepter.

* Arc Warden relies on items and abilities, as well as his Tempest Double, to deal damage to enemies. Doom effectively denies that and makes Arc Warden useless in fights.

* Multicast Fireblasts over the course of fights are a decent nuisance to stall Sven's massive damage output.
* Bloodlust and Ignite gives Ogre Magi's team the movement speed difference needed to chase and/or disengage against a Sven and his Warcry.
* Ignite provides strong damage over time to pressure Sven early on in the laning phase and keep his health low, delaying his transition into the jungle. Ignite is also an easy way to disrupt Blink Dagger, Sven's most popular way of initiation.
* Ogre Magi's presence in the laning phase both in terms of damage and durability keeps high pressure on Sven in lane.
* Purchasing an Aghanim's Shard allows Ogre Magi to greatly reduce the burst damage of Sven, who tends to build items focused on damage per hit instead of attack speed.

* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .

* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: Lifestealer, Doom, Mirana, Clinkz.

* An Aghanim's Scepter upgraded Doom can be useful against heroes with troublesome passive skills while also disabling them for a long time: Phantom Assassin, Enchantress, Huskar, Underlord.

Additional:
* Infernal Blade does damage based on percentage health, and is useful against high health pool hero like Underlord
* Doom can prevent Underlord from spamming his abilities and most important is prevent him from using Dark Rift to escape

* Doom shuts down Anti-Mage's escape capabilities with Blink. The ability also deals pure damage, which ignores the protection from Counterspell.
* However, a well-timed Counterspell can reflect it back.
* If Doom has Aghanim's Scepter, Doom can break Mana Break and Counterspell, weakening both his offense and defense.
* Doom's low mana pool causes him to take little damage from Mana Void.
Additional:
* Doom prevents Anti-Mage from maneuvering around a fight or escaping from an initiation using Blink. Additionally, Doom deals pure damage, which is not affected by Counterspell. This can quickly whittle away Anti-Mage's naturally poor health pool.
* Be careful when using Doom as a well-timed Counterspell can block and reflect it back against Doom himself.
* An Aghanim's Scepter upgraded Doom will also disable Mana Break and Counterspell, which makes Anti-Mage significantly less effective in fights and more susceptible to the high magical damage of Doom's abilities and his allies.