* Disruption sets up Anti-Mage for a chain disable. The illusions will deal extra damage due to Mana Break.
* Soul Catcher causes Anti-Mage to take a large chunk of damage, and can hit him when he is inside from Disruption.
* Shadow Poison hits Anti-Mage even after he's Blinked away.
Additional:
* While it is unwise to encounter Anti-Mage alone, Disruption's considerable cast range can become a perfect setup for any hard-disable to follow up. If he is pinned down, Anti-Mage will quickly face his demise when the illusions deplete his already low mana pool. Manta Style will easily allow him to escape, however.
* The illusions can be controlled to quickly sap mana from any other target, making Anti-Mage one of the most valuable targets to disrupt.

* Doom shuts down Anti-Mage's escape capabilities with Blink. The ability also deals pure damage, which ignores the protection from Counterspell.
* If Doom has Aghanim's Scepter, Infernal Blade can hit Anti-Mage loses his Mana Break and Counterspell, weakening both his offense and defense.
* Doom's low mana pool causes him to take little damage from Mana Void.
Additional:
* Doom prevents Anti-Mage from maneuvering around a fight or escaping from an initiation using Blink. Additionally, Doom deals pure damage, which is not affected by Counterspell. This can quickly whittle away Anti-Mage's naturally poor health pool.
* Be careful when using Doom as a well-timed Counterspell can block and reflect it back against Doom himself.
* An Aghanim's Scepter upgraded Infernal Blade will also disable Mana Break and Counterspell, which makes Anti-Mage significantly less effective in fights and more susceptible to the high magical damage of Doom's abilities and any allies'.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Axe more than most normal attacks, negating some of his tankiness. With Aghanim's Scepter, Counter Helix is also disabled, making him effectively useless for a lengthy duration.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Axe.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom's naturally low attack speed makes Counter Helix less likely to proc.
* Doom makes Axe less disruptive, preventing him from using his skills or items.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Axe.
* Doom has low attack speed because of his high Base-Attack-Time, poor agility gain and limited attack-speed granting items which are commonly built. This means Doom will trigger Counter Helix less often and thus is an unideal target for initiation.
* Doom has naturally high HP so it takes longer for Doom to be brought down to the killing threshold of Culling Blade.
* Axe is highly reliant on his abilities and items to be effective during a fight. Without the usage of Berserker's Call and Blink Dagger, Axe offers very little in the way of damage.

* Disruption will save Shadow Demon's teammates from being killed by Counter Helix or Culling Blade.
* Soul Catcher and Shadow Poison can put Axe's Blink Dagger on cooldown.
* Demonic Purge slows Axe to a crawl, making him nearly useless after initiating. If Shadow Demon has Aghanim's Scepter, it will also break Counter Helix.

* Disruption can banish Faceless Void or an ally in Chronosphere, making it less effective of an ability.
* Faceless Void's illusions created by Disruption will not get stunned by Chronosphere, allowing Shadow Demon to attack Faceless Void in his Chronosphere.
* Casting Disruption after releasing Shadow Poison charges will make Time Walk unable to backtrack the damage.
* Shadow Poison is a good way to deal damage as the initial damage and the release damage can't both be Time Walked at the same time.
* Demonic Purge is a great slow, useful to force out a Time Walk early and can break Time Lock with Aghanim's Scepter.

* Faceless Void relies on Time Walk for mobility and survivability but he can be prevented from utilizing it through Doom.
* Doom has a high cooldown duration for every ability except Infernal Blade, so he is not significantly affected by Time Dilation.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Spectre more than most normal attacks, negating some of her tankiness.
* With Aghanim's Scepter Dispersion and Desloate are disabled.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Spectre.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom makes Spectre less disruptive.

* Her illusions with Desolate is very valuable, especially when they are usually paired with Radiance. Unlike blink or force movement, Spectral Dagger's escaping mechanic requires manual movement, and therefore Demonic Purge can hold her back really hard allow your allies to finish her off.
* If she would try to kill you or any key ally with Haunt at any point of the game, remember to not panic and always use Disrupt on the illusion, whether it is fake or the real Spectre herself. When the situation calls, Demonic Purge can save a second victim from a haunting Spectre.
* When upgraded by Aghanim's Scepter, Demonic Purge can remove Spectre from a fight by disabling Desolate and Dispersion, negating her damage and tankiness respectively.

* Infernal Blade deals scaling damage and is useful against high health targets such as Bristleback.
* Doom disables Bristleback's low cooldown abilities, preventing him from triggering Warpath. With Aghanim's Scepter, it also breaks Bristleback's passive, rendering him more vulnerable.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Bristleback.
* If Doom gets an Aghanim's Scepter, he can disable Bristleback, taking away much of his durability.
* Doom prevents Bristleback from casting his two low cooldown abilities, which then prevents him from utilizing Warpath.

* Shadow Demon's Soul Catcher hinders Bristleback's tanking capabilities. Demonic Purge with Aghanim's Scepter disables Bristleback's passive.

* Ursa struggles against heroes with strong (and especially undispellable) disables (Disruptor, Puck, Shadow Demon, Outworld Devourer and etc).

* Doom makes Ursa less disruptive, and it cannot be dispelled with Enrage upgraded with Aghanim's Scepter.
* Aghanim's Scepter upgraded Infernal Blade can break Fury Swipes, negating much of his damage output.

* Heroes with high physical damage output but lack of reliable escape mechanisms are always a good target for a solo gank: Sniper, Shadow Fiend, Troll Warlord, Drow Ranger. Those heroes, however, are dangerous if they manage to close the gap, so take caution.

* Doom has several disable abilities to choose from jungle creeps (e.g. War Stomp, Ensnare) to deal with Shadow Fiend who lacks escape abilities.
* When Doom combines creep abilities with Scorched Earth, Infernal Blade, and Doom, Shadow Fiend most likely will die as he cannot use Shadowraze and Requiem of Souls to protect himself, and also cannot even flee by using Shadow Blade or Blink Dagger.
* Although Shadow Fiend has a high physical damage output, Doom has a large health pool to survive it, meaning Doom's combo with high magical damage output will shutdown Shadow Fiend first.
* Doom usually buys Radiance to improve his damage, making his nuke combo more deadly to Shadow Fiend. The blind also prevents Shadow Fiend from landing his attacks often.

* Tinker is heavily reliant on casting his spells and Doom can disable all of his abilities and items. An Aghanim's Scepter only makes it harder for Tinker to survive.
Additional:
* Tinker is heavily dependent on active abilities and Doom prevents him from using any of them.

* Heroes that can gain vision over trees to catch Tinker: Invoker, Shadow Demon, Batrider

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Heroes with abilities that break Berserker's Blood, lowering Huskar's attack speed and health regeneration: Doom, Shadow Demon, Viper.

* Heroes with abilities that break Berserker's Blood, lowering Huskar's attack speed and health regeneration: Doom, Shadow Demon, Viper.

* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Doom can eats Nature's Prophet's treants with Devour and gains lots of gold.
* Doom usually buys Radiance or using his Scorched Earth deals a lot of damage to Nature's Prophet if they stand close to his Treants, as well as killing all of his Treants and getting lots of gold.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Nature's Prophet:
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer, Satyr Tormenter and etc. are good examples.
* Doom and a ministun from Infernal Blade's prevents Nature's Prophet from escaping with Sprout and Teleportation.

* Disruption instantly removes Phantom Embrace, and can potentially save allies affected by Soulbind.
* Demonic Purge dispels Ink Swell.

* Doom disables the toggling of Rot and, if cast at the right time, may leave Pudge with a potentially lethal health drain.
* Doom's naturally high health, strength gain and damage output makes him a poor target for Pudge.
* The damage of Doom's Infernal Blade scales with the target's maximum health, which is particularly effective against Pudge due to his naturally high health and further health granted by stacks of Flesh Heap.
Additional:
* Infernal Blade deals high damage to Pudge due to his high strength grow with Flesh Heap.
* Using Doom with timing against Pudge who had just activated Rot would usually kill him.

* Shadow Demon's spammable illusions can be used to scout Techies' Proximity Mines. The illusion of your carries can be even used to trick Techies into detonating his precious Remote Mines.

* Doom can stop Death Prophet from casting spells, which makes her useless during team fights if she didn't cast Exorcism before the fight. Furthermore, Doom can use Scorched Earth to chase after her.

* Doom shuts down Timbersaw completely, negating his mobility and preventing him from doing any damage.
* Infernal Blade can stun Timbersaw several times in a fight, potentially interrupting Timber Chain. It also breaks Reactive Armor's passive bonuses from Aghanim's Scepter.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Timbersaw.
* Timbersaw is extremely reliant on his abilities to be effective during a teamfight - both for mobility, damage and crowd control. Timbersaw offers very little impactful right-click damage, and thus Doom is particularly crippling against this hero.
* Additionally, when upgraded with Aghanim's Scepter, Infernal Blade breaks Reactive Armor, which effectively removes the durability which Timbersaw is commonly known for.

* Doom completely takes Invoker out of a team fight, a hero who relies on using abilities and items to contribute.
Additional:
* Doom is a good way to shut down Invoker, preventing from casting spells and using items for a lengthy time, thus forcing him to invest on Linken's Sphere.

* Shadow Demon can waste precious seconds of Windrun with Disruption.
* Alternatively, Demonic Purge can be used to dispel it altogether, leaving her completely defenseless for 7 seconds.
* Disruption can be used to save an ally if they get stunned by Shackleshot.

* The constant dispel from Demonic Purge will make any attempt to save the victim or himself by Surge become futile. For what it's worth, Demonic Purge will also dispel Ion Shell.

* Doom is effective against every hero, and Void Spirit is no exception. Being unable to cast spells or items during fights for 16 seconds nullifies his impact entirely.
* Doom has a very versatile build and can consume creeps which has abilities that can stun or provide additional magic resistance.
* Doom's high strength gain and versatility in items can be effective against Void Spirit's magical damage.

* In the laning stage, making illusions of Venomancer will turn his Poison Sting back at him, making for an easy gank level one, and for later when your mid comes for ganks.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Elder Titan.
* Doom has very low base armor and naturally high HP, so he isn't significantly affected by Natural Order.

* Doom alone can easily pick off Crystal Maiden since she is fairly fragile, even with using only basic attacks, Infernal Blade, and Scorched Earth.
* Doom prevents her from using any abilities in a fight, making her impact negligible.
* Devour allows Doom to acquire a stun, allowing him to cancel Freezing Field without having to use Doom.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Tidehunter.
* If Doom gets an Aghanim's Scepter, he can also disable Kraken Shell, reducing his survivability and tankiness.
* Doom prevents Tidehunter from casting his Gush, Anchor Smash and Ravage, making him useless in team fights.

* Scorched Earth can be used to engage Visage while removing Gravekeeper's Cloak charges.
* Infernal Blade will deal tremendous amounts of damage over time due to Visage's high health pool.
* Doom completely nullifies Gravekeeper's Cloak and prevents Visage from casting spells.

* Arc Warden relies on items and abilities, as well as his {U:Tempest Double}, to deal damage to enemies. Doom effectively denies that and makes Arc Warden useless in fights.

* Heroes with summons or illusions to counter Flux, such as {Hero ID:Beastmaster} , Chen, or Shadow Demon.

* Doom makes Ogre Magi less disruptive.
* Infernal Blade effectively negates Ogre Magi's tankiness.
* With Aghanim's Scepter he can disable Multicast.

* Doom pierces spell immunity and can prevent Enigma from casting any spells or using items until the duration of the spell depletes, as well as damaging him over time. This can however, be blocked by a Linken's Sphere.
* An Enigma with a Helm of the Dominator can potentially feed his dominated creeps to Doom's Devour, giving Doom the abilities and benefits instead.

* Scorched Earth deals damage to Clinkz during Skeleton Walk.
* Doom shuts down Clinkz entirely, as it prevents him from casting any of his spells and contributing a large amount of damage in teamfights.

* Doom will make Abaddon unable to use Mist Coil, Aphotic Shield, and the active component of Borrowed Time, which means his allies could be easily disabled or killed.
* Infernal Blade upgraded with Aghanim's Scepter can break Curse of Avernus and the passive component of Borrowed Time. It also deals high damage due to Abaddon's high health.

* Shadow Demon with an Aghanim's Scepter will use Demonic Purge to disable Curse of Avernus and the passive component of Borrowed Time. If this is combined with a silence, Borrowed Time will not trigger at all.
* Even without Aghanim's Scepter, he can still waste Borrowed Time with Disruption. Curse of Avernus fully works on illusions, turning the passive ability against him.

* Similarly, they can negate your X Marks The Spot & Torrent combo by protecting your target when you use Return. Good candidates to negate your combo include Outworld Devourer and his Astral Imprisonment, and Shadow Demon and his Disruption.
* Heroes with hide abilities can often dodge a Ghostship just before it hits.
* Similarly, they can negate your X Marks The Spot & Torrent combo by protecting your target when you use Return. Good candidates to negate your combo include Outworld Devourer and his Astral Imprisonment, and Shadow Demon and his Disruption.
* A Eul's Scepter of Divinity can also do the trick, but, unlike the previously mentioned abilities, you can only use it on yourself and not your allies.

* Heroes with Break abilities will prevent Slark to regenerate and gaining Essence Shift stacks: Viper, Shadow Demon etc.

* Heroes with silencing abilities can be particularly deadly when Slark is trying to escape: Silencer, Death Prophet, Puck, Doom

* Heroes with high physical damage output but lack of reliable escape mechanisms are always a good target for a solo gank: Sniper, Shadow Fiend, Troll Warlord, Drow Ranger. Those heroes, however, are dangerous if they manage to close the gap, so take caution.

* Heroes that lose a great amount of their tankiness and become easier to finish off: Bristleback, Spectre, Phantom Assassin, Enchantress, Dragon Knight.
* Once you have an Aghanim's Scepter, Shadow Demon instantly reach a new power spike and become a counter for a variety of heroes that have strong passives.
* Heroes that lose a great amount of their tankiness and become easier to finish off: Bristleback, Spectre, Phantom Assassin, Enchantress, Dragon Knight.
* Heroes that lose a great amount of damage output and become less threatening: Phantom Assassin, Sven, Slark, Phantom Lancer.
* You can always stack camps and farm the scepter with Shadow Poison.

* Silencer's Global Silence and Doom's Doom makes Earthshaker temporarily useless.

* Heroes with abilities that can save are also effective such as Shadow Demon, Dazzle, Oracle, Bane, Pugna, Tusk, Winter Wyvern, Io, Underlord, Treant Protector and Keeper of the Light.

Additional:
* Be ready to save an ally from Omnislash with your Disruption.
* Spawning Juggernaut's illusions is a great deal, as his base attack time is low and he has a critical strike. Illusions will benefit from both.
* Demonic Purge will prevent Juggernaut's desperate attempt to flee using Blade Fury. However, it cannot stop him if he is using Town Portal Scroll.

* Heroes that create illusions (such as Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress and the aforementioned Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. (However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse).

Additional:
* Demonic Purge takes off Luna's superior mobility, removing the need for chasing her and allowing your team to reposition in team fights or escape when at low HP. If Shadow Demon has Aghanim's Sceptre it will also take away glaive bounces and extra damage from Luna's passive.
* Luna's illusions created by Disruption is very valuable with their Moon Glaives. These will effectively counter her pushing attempts and are painfully effective in team fights.
* Disruption can be used to save an ally from Eclipse.

* Heroes with ways to protect themselves or allies from Spirit Breaker's initiation: Shadow Demon

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

* Heroes with hiding abilities can protect disabled allies: Outworld Devourer, Shadow Demon, Tusk, Phoenix with Aghanim's Scepter

* Heroes that can punish aggressive heroes, such as: Leshrac, Shadow Demon, Pugna, Death Prophet.

* Doom prevents Storm Spirit from using all of his abilities and items, rendering Storm Spirit useless in a fight.

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

* Disruption can protect Shadow Demon's allies from Fortune's End, preserving healing or buffs. It can also catch Oracle's allies, allowing Shadow Poison and Soul Catcher to be used without being dispelled.
* Demonic Purge prevents over-time healing during False Promise, such as Purifying Flames and Urn of Shadows. If he has Aghanim's Scepter, this issue can persist for longer or on multiple allies.
* It will not, however, prevent healing from instant abilities, items, or auras, making Mekansm a good choice against him.

* A well-timed Doom prevents Nyx Assassin escaping with Vendetta and does not allow him to disengage with Spiked Carapace.
* Doom's high HP easily shrug off Nyx Assassin's burst damage and fend him off.

* Heroes that can purge buffs can dispel Guardian Angel: Invoker, Shadow Demon, Oracle.

Additional:
* Demonic Purge can dispel Guardian Angel on the key target during combat, allow your allies to finish them.

* Doom turns Omniknight into a walking creep, or completely takes out his buffed cores, also removing Guardian Angel in the process.
* Doom has access to Satyr Banisher's Purge, which allows him to remove Guardian Angel.
Additional:
* Doom applies a basic dispel upon cast, so it can remove Guardian Angel.
* Casting Doom on Omniknight will prevent him from healing allies with Purification, or casting buffs like Heavenly Grace and Guardian Angel.

* Heroes with high physical damage output but lack of reliable escape mechanisms are always a good target for a solo gank: Sniper, Shadow Fiend, Troll Warlord, Drow Ranger. Those heroes, however, are dangerous if they manage to close the gap, so take caution.

* Any heroes with silences can negate the majority of Outworld Devourer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .

* Heroes with break abilities: Nyx Assassin, Shadow Demon (with Aghanim's Scepter), Viper.

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

Additional:
* Doom can completely shut down Dazzle through Doom, as it prevents him from casting his abilities and, by extension, gaining Bad Juju stacks.

* Alchemist is a well-known Radiance carrier among other auras your illusions will benefit from. They also get the extra move speed and reduced base attack time from his Chemical Rage, and it's even better if you can catch him as his own rage is about to expire.
* Disruption will buy enough time for all allies to retreat when Alchemist starts to activate Unstable Concoction.

* Heroes who can hide the Dueled target (Outworld Devourer, Shadow Demon, Tusk, Phoenix with Aghanim's Scepter etc).

Additional:
* Disruption can save allies and mess up an initiation from an enemy Legion Commander. Using Disruption on your ally that is affected by Duel will leave her totally exposed without the benefit of the life steal from Moment of Courage. A precise decision to Disrupt Legion Commander or her victim is crucial to waste Duel's potential.
* Demonic Purge cannot be dispelled by a hard dispel from Press the Attack, which in turn can be dispelled by your ultimate.

* Shadow Demon, Outworld Devourer and Tusk can all save a Lasso'd teammate with their defensive spells.

* Heroes that can dominate his illusions or create their own illusions of him: Dark Seer, Morphling, Enchantress, Shadow Demon.

* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: Lifestealer, Doom, Mirana, Clinkz.

* Disruption can save an ally from a fatal Reaper's Scythe.
* Demonic Purge can remove Ghost Shroud, making Necrophos vulnerable to physical damage and preventing him from regenerating health.

* An Aghanim's Scepter-upgraded Infernal Blade can be useful against heroes with troublesome passive skills: Phantom Assassin, Enchantress, Huskar, Underlord.

Additional:
* Infernal Blade does damage based on percentage health, and is useful against high health pool hero like Underlord
* Doom can prevent Underlord from spamming his abilities and most important is prevent him from using Dark Rift to escape