* Doom shuts down Anti-Mage's escape capabilities with Blink. The ability also deals pure damage, which ignores the protection from Counterspell.
* However, a well-timed Counterspell can reflect it back.
* If Doom has Aghanim's Scepter, Doom can break Mana Break and Counterspell, weakening both his offense and defense.
* Doom's low mana pool causes him to take little damage from Mana Void.
Additional:
* Doom prevents Anti-Mage from maneuvering around a fight or escaping from an initiation using Blink. Additionally, Doom deals pure damage, which is not affected by Counterspell. This can quickly whittle away Anti-Mage's naturally poor health pool.
* Be careful when using Doom as a well-timed Counterspell can block and reflect it back against Doom himself.
* An Aghanim's Scepter upgraded Doom will also disable Mana Break and Counterspell, which makes Anti-Mage significantly less effective in fights and more susceptible to the high magical damage of Doom's abilities and his allies.

* Heroes who take a long time to become strong are in for a rough mid game, such as Outworld Destroyer, Magnus, Medusa, and Anti-Mage.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Spectre more than most normal attacks, negating some of her tankiness.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Spectre.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom makes Spectre less disruptive. Combined with Aghanim's Scepter, it will disable Spectre passive skills, reducing her potential in teamfights.
Additional:
* Infernal Blade's damage is calculated by percentage of max health. Since Spectre is usually tanky, it will hurt her more than most normal attacks.
* Doom can entirely disable Spectre from a teamfight. If upgraded with Aghanim's Scepter, it will disable her passive skills which is she relies on, crippling her.

* Void Spirit is strong against heroes who cannot deal with his rotations due to his mobility. Such heroes include Spectre, Gyrocopter, Morphling, and Chen.

* Void Spirit deals entirely magical damage in the early game, ignoring her evasion from Windrun.
* A Void Spirit with fast reaction time can use Dissimilate or Astral Step to dodge Powershot.

* Doom completely takes Invoker out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Additional:
* Doom is a good way to shut down Invoker, preventing from casting spells and using items for a lengthy time, thus forcing him to invest on Linken's Sphere.

* Arc Warden relies on items and abilities, as well as his Tempest Double, to deal damage to enemies. Doom effectively denies that and makes Arc Warden useless in fights.

* Scorched Earth can be used to engage Visage while removing Gravekeeper's Cloak charges.
* Infernal Blade will deal tremendous amounts of damage over time due to Visage's high health pool.
* Doom completely nullifies Gravekeeper's Cloak and prevents Visage from casting spells.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Bristleback.
* Doom prevents Bristleback from casting his two low cooldown abilities, which then prevents him from utilizing Warpath.
* If Doom gets an Aghanim's Scepter, he can disable Bristleback and Warpath, taking away much of his durability and damage potential in team fights.
Additional:
* Infernal Blade deals scaling damage and is useful against high health targets such as Bristleback.
* Doom disables Bristleback's low cooldown abilities, preventing him from triggering Warpath. With Aghanim's Scepter, it also breaks Bristleback's passive, rendering him more vulnerable.

* Void Spirit's AoE damage make short work of Broodmother's spiderlings
* Broodmother cannot escape Void Spirit's mobility, even in her webs.
Additional:
* Void Spirit's AoE damage make short work of Broodmother's spiderlings
* Broodmother cannot escape Void Spirit's mobility, even in her webs.

* Tinker is heavily reliant on casting his spells and Doom can disable all of his abilities and items. An Aghanim's Scepter only makes it harder for Tinker to survive.
Additional:
* Tinker is heavily dependent on active abilities and Doom prevents him from using any of them.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Timbersaw.
* Timbersaw is extremely reliant on his abilities to be effective during a team fight - both for mobility, damage and crowd control. Timbersaw offers very little impactful right-click damage, and thus Doom is particularly crippling against this hero.
* Additionally, when upgraded with Aghanim's Scepter, Doom breaks Reactive Armor, which effectively removes the durability which Timbersaw is commonly known for.
Additional:
* Doom shuts down Timbersaw completely, negating his mobility and preventing him from doing any damage. It also breaks Reactive Armor's passive bonuses from Aghanim's Scepter.
* Infernal Blade can stun Timbersaw several times in a fight, potentially interrupting Timber Chain. Also it's useful since Timbersaw has high HP due to the damage scales based on max HP.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Tidehunter.
* Doom prevents Tidehunter from casting his Gush, Anchor Smash and Ravage, making him useless in team fights.
* If Doom gets an Aghanim's Scepter, he can also disable Kraken Shell, reducing his survivability.

* Scorched Earth deals damage to Clinkz during Skeleton Walk.
* Doom shuts down Clinkz entirely, as it prevents him from casting any of his spells and contributing a large amount of damage in teamfights.

* Doom alone can easily pick off Crystal Maiden since she is fairly fragile, even with using only basic attacks, Infernal Blade, and Scorched Earth.
* Doom prevents her from using any abilities in a fight, making her impact negligible.
* Devour allows Doom to acquire a stun, allowing him to cancel Freezing Field without having to use Doom.

* Doom prevents Storm Spirit from using all of his abilities and items, rendering Storm Spirit useless in a fight.

* Doom has several disable abilities to choose from jungle creeps (e.g. War Stomp, Ensnare) to deal with Shadow Fiend who lacks escape abilities.
* When Doom combines creep abilities with Scorched Earth, Infernal Blade, and Doom, Shadow Fiend most likely will die as he cannot use Shadowraze and Requiem of Souls to protect himself, and also cannot even flee by using Shadow Blade or Blink Dagger.
* Although Shadow Fiend has a high physical damage output, Doom has a large health pool to survive it, meaning Doom's combo with high magical damage output will shutdown Shadow Fiend first.
* Doom usually buys Radiance to improve his damage, making his nuke combo more deadly to Shadow Fiend. The blind also prevents Shadow Fiend from landing his attacks often.

* Doom disables the toggling of Rot and, if cast at the right time, may leave Pudge with a potentially lethal health drain.
* Doom's naturally high health, strength gain and damage output makes him a poor target for Pudge.
* The damage of Doom's Infernal Blade scales with the target's maximum health, which is particularly effective against Pudge due to his naturally high health and further health granted by stacks of Flesh Heap.
Additional:
* Infernal Blade deals high damage to Pudge due to his high strength grow with Flesh Heap.
* Using Doom with timing against Pudge who had just activated Rot would usually kill him.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Elder Titan. It also can interupt Echo Stomp if quick enough.
* Doom has very low base armor and naturally high HP, so he isn't significantly affected by Natural Order.

* Doom can eats Nature's Prophet's treants with Devour and gains lots of gold.
* Doom usually buys Radiance or using his Scorched Earth deals a lot of damage to Nature's Prophet if they stand close to his Treants, as well as killing all of his Treants and getting lots of gold.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Nature's Prophet:
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer, Satyr Tormenter and etc. are good examples.
* Doom and a ministun from Infernal Blade's prevents Nature's Prophet from escaping with Sprout and Teleportation.

* Keeping Void Spirit inside Wukong's Command is a very tricky task, especially in the early and mid game. In addition, if Monkey King is in a bad position, a well placed Aether Remnant can easily pull him out of the ring.
* Getting stacks of Jingu Mastery can be difficult when attacking Void Spirit.

* Doom pierces spell immunity and can prevent Enigma from casting any spells or using items until the duration of the spell depletes, as well as damaging him over time. This can however, be blocked by a Linken's Sphere.
* An Enigma with a Helm of the Dominator can potentially feed his dominated creeps to Doom's Devour, giving Doom the abilities and benefits instead.

* Faceless Void relies on Time Walk for mobility and survivability but he can be prevented from utilizing it through Doom.
* Doom has a high cooldown duration for every ability except Infernal Blade, so he is not significantly affected by Time Dilation.

* Void Spirit can easily dodge Gyrocopter's {Ability ID:Homing Missile|gyrocopter} with the help of Dissimilate.
* Void Spirit can partly dodge Call Down via Dissimilate or move out of its range with Astral Step.
* Gyrocopter has no escape abilities, which benefits Void Spirit's high mobility.

* Dissimilate and Astral Step allow Void Spirit to quickly escape from Cold Feet.
* Void Spirit deals both magical and physical damage, which makes Ancient Apparition an easy target to ambush.
* If Void Spirit purchases Aghanim's Scepter, the silence provided by Resonant Pulse can disrupt Ancient Apparition during fights, as he is entirely reliant upon spells to contribute.

* Heroes with considerable mobility can easily escape from a rolling Pangolier: Anti-Mage, Queen of Pain, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, moreover, if a player is familiar with how Rolling Thunder works, they can adjust their movement to avoid it entirely and of course outplay the Pangolier player.

* Heroes who take a long time to become strong are in for a rough mid game, such as Outworld Destroyer, Magnus, Medusa, and Anti-Mage.

* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

* Heroes that can summon units will have their summons destroyed very quickly if badly micro-managed, like Chen, Lycan, and Phantom Lancer.

* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: Lifestealer, Doom, Mirana, Clinkz.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper

* Heroes that can reliably kite out Dispose, Unleash and dodge Rebound, like Ember Spirit, Void Spirit, Storm Spirit, Anti-Mage, Faceless Void, Puck or always build items like Blink Dagger and Force Staff.

* Heroes who take a long time to become strong are in for a rough mid game, such as Outworld Destroyer, Magnus, Medusa, and Anti-Mage.

* Heroes with silencing abilities can be particularly deadly when Slark is trying to escape: Silencer, Death Prophet, Puck, Doom

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Silencer's Global Silence and Doom's Doom makes Earthshaker temporarily useless.

* Heroes that can summon units will have their summons destroyed very quickly if badly micro-managed, like Chen, Lycan, and Phantom Lancer.

* Heroes with abilities that break Berserker's Blood, lowering Huskar's attack speed and health regeneration: Doom, Shadow Demon, Viper.

* Doom's Doom marks Phantom Lancer with a highly visible effect, and also silences him.
* Heroes with undispellable debuffs will help identify the real Phantom Lancer through visual effects or debuff indicators, provided that it was cast on the real Phantom Lancer to begin with:
* Doom's Doom marks Phantom Lancer with a highly visible effect, and also silences him.
* Bloodseeker's Rupture shows a clear red trail effect on the real Phantom Lancer.
* Ancient Apparition's Ice Blast will only debuff Phantom Lancer and not his illusions.
* Grimstroke's Soulbind is undispellable.
* Shadow Demon's Demonic Purge is undispellable.
* Monkey King's Jingu Mastery is undispellable and puts a big yellow Mark over his head.

* Astral Step and Dissimilate makes a quick work of Phantom Lancer's illusions.
* Resonant Pulse helps clear illusions and protects Void Spirit from Phantom Lancer's physical damage and with the Aghanim's Scepter upgrade, it prevents Phantom Lancer from casting his abilities.
* Void's Spirit mobility makes it hard for him to chase down with Phantom Rush.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Void Spirit's high mobility becomes a nuisance to Terrorblade.
* Void Spirit's arsenal of magic damage is effective against Terrorblade's low strength.
* Terrorblade has no disables to prevent Void Spirit from escaping.

* A well-timed Doom prevents Nyx Assassin escaping with Vendetta and does not allow him to disengage with Spiked Carapace.
* Doom's high HP easily shrug off Nyx Assassin's burst damage and fend him off.

* Doom can completely shut down Dazzle through Doom, as it prevents him from casting his abilities and, by extension, gaining Bad Juju stacks.

* Doom turns Omniknight into a walking creep, or completely takes out his buffed cores, also removing Guardian Angel in the process.
* Doom has access to Satyr Banisher's Purge, which allows him to remove Guardian Angel.
Additional:
* Doom applies a basic dispel upon cast, so it can remove Guardian Angel.
* Casting Doom on Omniknight will also prevent him from healing allies with Purification, or casting buffs like Heavenly Grace and Guardian Angel, basically turning him into a harmless creep.

* Doom makes Ursa less disruptive, and it cannot be dispelled with Enrage upgraded with Aghanim's Scepter.
* Aghanim's Scepter upgraded Infernal Blade can break Fury Swipes, negating much of his damage output.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Axe more than most normal attacks, negating some of his durability.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Axe.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom's naturally low attack speed makes Counter Helix less likely to proc, and his high base health allows him to take a few Helixes with no danger.
* Doom makes Axe less disruptive, preventing him from using his skills or items. With Aghanim's Scepter, Counter Helix is also disabled, making him effectively useless for a lengthy duration.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Axe.
* Doom has low attack speed because of his high Base-Attack-Time, poor agility gain and limited attack-speed granting items which are commonly built. This means Doom will trigger Counter Helix less often and thus is an unideal target for initiation.
* Doom has naturally high HP so it takes longer for Doom to be brought down to the killing threshold of Culling Blade.
* Axe is highly reliant on his abilities and items to be effective during a fight. Without the usage of Berserker's Call and Blink Dagger due to Doom, Axe offers very little in the way of damage, effectively removing him from a fight.

* Void Spirit can greatly pressure Morphling's farm, which is very bad for a hero who needs a large amount of space.
* Waveform does not provide better mobility than Astral Step.
* If Morphling shifted all of his strength to agility, he can be bursted down by Void Spirit before he can react.
* Doing an Ethereal Blade combo on Void Spirit is incredibly difficult, as Dissimilate and Astral Step can allow him to escape or dodge the projectile.

* Doom makes Ogre Magi less disruptive.
* Infernal Blade effectively negates Ogre Magi's durability.
* With Aghanim's Scepter, he can disable Multicast.

* Besides Lone Druid and Meepo, Doom is potentially good versus every hero since Doom will render any hero helpless for a prolonged 16 seconds. This is particularly true for fragile heroes that heavily rely on mobility to stay alive.

* Void Spirit can dodge Earthbind with Dissimilate and Astral Step, giving him a good chance to escape. If he gets caught anyways, Resonant Pulse allows him to retaliate.

* Ember Spirit cannot use his Activate Fire Remnant to escape while under effect from Doom.

* Doom can stop Death Prophet from casting spells, which makes her useless during team fights if she didn't cast Exorcism before the fight. Furthermore, Doom can use Scorched Earth to chase after her.

* An Aghanim's Scepter upgraded Doom can be useful against heroes with troublesome passive skills while also disabling them for a long time: Phantom Assassin, Enchantress, Huskar, Underlord.

Additional:
* Infernal Blade does damage based on percentage health, and is useful against high health pool hero like Underlord
* Doom can prevent Underlord from spamming his abilities and most important is prevent him from using Dark Rift to escape