* Bristleback's tankiness and damage reduction from the rear makes him very hard for Phantom Lancer to chase and finish off, due to his lack of burst damage.
* Quill Spray destroys Phantom Lancer's illusions.
* Bristleback's passive costs no mana, meaning that it will continue to trigger even if Phantom Lancer drains Bristleback's mana with Diffusal Blade.
Additional:
* Quill Spray cleans up Phantom Lancer's illusions in no time.
* Phantom Lancer's complete lack of burst damage makes it nearly impossible for him to kill Bristleback during chases.

* Breathe Fire and Elder Dragon Form's splash damage takes out Phantom Lancer's illusions quickly.
* If Dragon Knight can Dragon Tail the real Phantom Lancer, he and his team can quickly kill him before he has a chance to escape.

* Dragon Blood's armor bonus greatly reduces the damage dealt by Phantasm.
* Breathe Fire and Elder Dragon Form's splash damage quickly destroy illusions and reduces their damage output.

* Quill Spray quickly destroys Chaos Knight's Phantasms.

* Riki does little damage to Dragon Knight, as he relies only on physical damage with modest attack speed and lack of burst.

* The bonus Backstab damage from Cloak and Dagger is rendered irrelevant with Bristleback and hurts Riki more than him because of the passive Quill Spray.
* Riki still gets damaged by Bristleback's Quill Spray while invisible, and it can be hard to deal with in lane.
* Bristleback is not too bothered by Smoke Screen. Though he cannot use Quill Spray manually inside it, it still procs passively when he takes damage from the back. The movement speed from Warpath allows him to get out of the area easily.
* Due to Bristleback's natural tankiness, he is an ideal Gem of True Sight carrier.
* Riki rarely buys Silver Edge to break Bristleback's passive because the invisibility aspect of it is redundant.
Additional:
* Quill Spray will hit Riki even when he is invisible.
* Cloak and Dagger's bonus backstab damage is rendered irrelevant against Bristleback.
* Smoke Screen does not stop Bristleback's passive from activating.
* Due to Bristleback's natural tankiness, he is an ideal Gem of True Sight carrier, directly countering Riki's invisibility.

* Heroes who continue dealing damage while being stunned: Luna, Razor, Axe, Bristleback, Leshrac,

* Spirit Breaker's slow attack speed and moderate damage do very little to harm Dragon Knight, even if ganked with Charge of Darkness.

* Dragon Knight's insanely high armor and splash damage can cause Lycan to struggle taking him down.

* Lycan's wolves deal little damage to Bristleback, and are easily killed by Quill Spray, even when they're invisible.
* Lycan's lack of burst damage makes it very hard for him to kill Bristleback, especially when his back is turned.
Additional:
* Quill Spray can be used to kill Lycan's summons.
* Bristleback allows him to stay alive against Lycan while dishing out counter attacks
* He can overpower Lycan with his Warpath instead.

* Broodmother's spiderlings and spiderites do almost nothing against Dragon Knight.

Additional:
* Breathe Fire will clear Broodmother's spiderites while significantly damaging her spiderlings and decreasing their damage output.
* Dragon Blood's added armor and regen mitigates the damage done by Broodmother and her spiders.
* Elder Dragon Form at level 2 and above applies splash damage to Dragon Knight's auto attacks.

* Quill Spray destroys spiderlings, and hits Broodmother even when she's regenerating in her webs. This makes Bristleback one of her hardest counters in lane.
Additional:
* Bristleback reduces most of Broodmother's and her spiderlings' damage.
* Quill Spray will hit any spiders in its proximity, hindering Broodmother's fighting and farming capabilities.

* Heroes with high physical damage can damage Lifestealer more than he can heal: Bristleback, Clinkz, Luna,Shadow Fiend, Slardar

* Heroes that rely on physical damage are ineffective against Dragon Knight due to his high armor: Phantom Assassin,Bloodseeker, Lifestealer, Troll Warlord

* Quill Spray is very effective against Io, as it has very low armor and has to stay close to the fight to not break its Tether.

* Quill Spray usually hits Meepo's clones, although Bristleback cannot turn his back when rooted with Earthbind.

* Bristleback decreases Tiny's high burst damage against Bristleback.
* Tiny's high damage will also proc Bristleback multiple times.
* Viscous Nasal Goo can help counteract the bonus armor granted by Grow.

* Death Ward does little damage against Dragon Knight's armor, and Dragon Knight's high health regeneration minimizes damage from Maledict.

* Bristleback is one of the hardest heroes to gank with a Meat Hook and Dismember combo, and attempts to do so sometimes backfire on Pudge.
Additional:
* Pudge is particularly susceptible to Bristleback's Viscous Nasal Goo and Quill Spray due to his naturally low armor & poor agility gain.
* Bristleback, in combination with his strength gain, high health, common itemization for magic resistance and damage reduction from Bristleback makes him a poor target for Pudge.

* Bristleback's abilities are nearly useless for Rubick to Spell Steal, as he does not gain the bonuses from Warpath.
Additional:
* Rubick deals little damage on his own, so Bristleback can simply shrug off all his spells and chase you down with his spells and attacks.
* Quill Spray requires multiple casts and close range to add up stacks. Because Rubick does not stay in the front lines, it's generally not a good spell for him to steal.
* Viscous Nasal Goo will slow Rubick down even further and reduce his armor, making him vulnerable to Quill Spray and the damage bonus from Warpath.

* Despite the armor reduction from Meld, Templar Assassin's reliance on physical damage and medium attack speed is unlikely to harm Dragon Knight.
* Templar Assassin's Refraction charges also get quickly removed by the damage over time from Dragon Knight's ultimate.
Additional:
* The damage over time from Dragon Knight's Elder Dragon Form rapidly burns down Refraction, allowing him to attack her. Also, Breathe Fire reduces Templar Assassin's damage and Dragon Tail is a stun with a considerable duration, letting him and his team whittle her health down once her defenses wear off.

* Dragon Knight's heavy armor negates Vendetta's burst physical damage. His large HP pool also gives him a good chance of surviving Nyx Assassin's follow-up nuke damage.

* Macropyre's frequent damage ticks causes Bristleback to activate repeatedly, resulting in free damage as long as Bristleback faces away from Jakiro.

* Lone Druid and The Spirit Bear cannot burst down Bristleback due to Bristleback
* Bristleback can easily run to Lone Druid without any hesitation, with Viscous Nasal Goo to reduce armor and slow the Spirit Bear or Lone Druid and Quill Spray can deal damage to both Lone Druid and the Spirit Bear at the same time

* Dragon Knight can simply tank and destroy all Shadow Shaman's Serpent Wards.

* Quill Spray and Bristleback harass Luna more efficiently than she does with Lucent Beam.
* Bristleback withstands Luna’s nukes, and gives lots of damage in return.
* Viscous Nasal Goo and Warpath are enough to outrun a speedy Luna.
* Bristleback tends to be a frequent carrier of Crimson Guard, which is good protection from bouncing glaives.
Additional:
* Multiple instances of damage from Eclipse will trigger Bristleback's passive repeatedly in a short time, dealing tremendous damage to Luna and her teammates.
* Luna's damage burst may be high, but it will not be enough for her to take down Bristleback.

* Fortune's End cannot dispel Warpath stacks on Bristleback or Quill Spray stacks on allies.
* Bristleback can heavily reduce Oracle's damage output. With it, Oracle may accidentally heal Bristleback with Purifying Flames, especially if Bristleback has bonus magic resistance.

* Viscous Nasal Goo can hinder Crystal Maiden's already abysmal mobility, which allows Bristleback (or his teammates) to run her down and kill her.
* Bristleback frequently builds Blade Mail, which can quickly kill Crystal Maiden if her ultimate is used while he is under its effect.
* The passive part of Bristleback will trigger many, many times under the damage from Freezing Field, and as the stacks increase, the damage output from each successive cast (or proc) will eat away at Crystal Maiden's small HP pool.

* Quill Spray's constant AoE damage will hit Dark Willow even in Shadow Realm. Its automatic damage will hurt her if she tries to get close and use Bedlam.

* Bristleback's tankiness can enable him to chase Enigma out of a teamfight, making it difficult to initiate with a Black Hole.

* Bristleback need not worry about charging into Magnetic Field, and quickly clearing up Arc Warden's summons and Tempest Double with Quill Spray.
Additional:
* Bristleback activates frequently while he escapes from Arc Warden's Necronomicon army.
* Arc Warden has little armor and mobility, which makes him an easy target to apply Quill Spray and Viscous Nasal Goo stacks.

* Bloodseeker's physical damage is unlikely to kill Dragon Knight, and therefore rarely get a chance to recover the large amount of HP from Bloodrage.

* The extra damage from Searing Arrows is largely blocked by Dragon Knight's armor.

* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe

* Bristleback, Centaur Warrunner, Spirit Breaker, Pudge, Huskar: These heroes are too tanky for Puck to burst down. Also, all of them have spells which can deal with and shut Puck down reliably.

* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.

* Heroes with cleave abilities and area of effect damage can make quick work of Chen's converted creeps and at same time gain farm: Magnus, Jakiro, Shadow Fiend, Kunkka, Luna, Dragon Knight, Medusa, Alchemist.

* Durable heroes can fight with stand against Tusk during 1v1: Axe, Dragon Knight, Night Stalker, Centaur Warrunner, Wraith King and more.

* Heroes that rely on physical damage are ineffective against Dragon Knight due to his high armor: Phantom Assassin,Bloodseeker, Lifestealer, Troll Warlord

Additional:
* High armor thanks to Dragon Blood makes it difficult for Phantom Assassin to burst down Dragon Knight, as she deals 100% physical damage.
* Dragon Tail stuns Phantom Assassin as soon as she initiates, preventing her from gaining bonus attack speed.
* Dragon Knight is one of the few heroes who can safely solo lane against Phantom Assassin alongside a support.

* Cleave heroes will clear her illusions. Such heroes include Sven, Magnus, Dragon Knight in Elder Dragon Form, Ember Spirit (via item), Phantom Assassin (via talent or item), etc.

* Any hero who can survive Magnus's initiations and manfight him: Huskar, Faceless Void, Weaver, Abaddon, Troll Warlord, Alchemist, Dragon Knight, Night Stalker, Viper.

* Heroes that rely on physical damage are ineffective against Dragon Knight due to his high armor: Phantom Assassin,Bloodseeker, Lifestealer, Troll Warlord

* Heroes who can match Void Spirit's mobility (like the aforementioned Ember Spirit or Queen of Pain) or tank his spells (Dragon Knight or Centaur Warrunner) are very problematic for him.

* Bristleback's Viscous Nasal Goo can catch and slow Bounty Hunter. Warpath and Quill Spray can defeat him quickly due to his small HP pool when compared to Bristleback's.

* Heroes with high armor and/or durability can handle Juggernaut's ultimate, such as Sven and Dragon Knight.

* Heroes that are hard to gank: Dragon Knight, Mars, Centaur Warrunner.

* Dragon Tail can be used to cancel Requiem of Souls.
* Breathe Fire reduces Shadow Fiend's damage even further.
* Dragon Knight's high strength and Dragon Blood means that he'll be able to tank Shadow Fiend's right clicks.

* Bristleback's tankiness and Bristleback allow him to outlast Burning Spears' damage-over-time at almost any point in the game. In addition, if Huskar chooses to cast Life Break on Bristleback, Bristleback can simply turn around before it hits and receive little damage.
* Viscous Nasal Goo will reduce Huskar's low armor even further, and Quill Spray and Warpath will tear him down extremely quickly.
Additional:
* The damage from Burning Spear can be reduced by turning away from Huskar.
* Bristleback can bait Huskar into using Life Break on him, then turn around and receive very little damage.

* Quill Spray will hit Sand King inside Sand Storm, damaging him and putting Sand King's Blink Dagger on cooldown, preventing him from escaping.
* Epicenter's numerous damage ticks will trigger Bristleback's passive repeatedly during teamfights.

* If Silencer can't prevent Dragon Knight from using Elder Dragon Form, Silencer's spells aren't going to be that effective against him, as Dragon Knight relies on right-clicks and not spells.
* Dragon Blood's armor bonus and health regeneration allows Dragon Knight to stay in the lane against Glaives of Wisdom.
* Dragon Knight often builds Black King Bar, allowing him to remove Global Silence before engaging.

* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Dragon Knight's high natural sustain and health regeneration from Dragon Blood makes him hard to take down in Duels.

* Heroes with damage-over-time abilities will not only proc Bristleback's passive continuously, they will also do little harm to him when he is facing away from the source: Venomancer, Arc Warden