* Dragon Knight's heavy armor negates Vendetta's burst physical damage. His large HP pool also gives him a good chance of surviving Nyx Assassin's follow-up nuke damage.

* Rage completely negates all of Nyx Assassin's abilities except Vendetta, while Open Wounds allow him to quickly close the gap.
* Infest combined with an ancient creep makes Nyx Assassin an easy target with Dust of Appearance or a Gem of True Sight.

* Heroes with cleave abilities and area of effect damage can make quick work of Chen's converted creeps and at same time gain farm: Magnus, Jakiro, Shadow Fiend, Kunkka, Luna, Dragon Knight, Medusa, Alchemist.

* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: Lifestealer, Doom, Mirana, Clinkz.

* Heroes with burst damage of their own won't be afraid to go toe to toe with Void Spirit, like Ursa, Lifestealer, or Axe.

* Heroes who can match Void Spirit's mobility (like the aforementioned Ember Spirit or Queen of Pain) or tank his spells (Dragon Knight or Centaur Warrunner) are very problematic for him.

* Rage allows him to dispel Blinding Light from himself.
* Open Wounds allows him to slow and kill Keeper of the Light.

* Lifestealer can close the distance to Sniper by using Infest on a fast or durable creep to tank Sniper's damage.
* Open Wounds will reduce Sniper's mobility heavily, and Rage's attack speed bonus helps in taking down Sniper.

* Rage negates Kunkka's X Marks the Spot.
* As a strength hero with high strength gain and very little armor, as well as low agility gain, Kunkka is vulnerable to Lifestealer's Feast and Open Wounds.

* Rage will dispel Laser's blind and turns him spell immune for the duration so Tinker cannot damage him.
* Feast will quickly bring down Tinker due to being so fragile.
Additional:
* Lifestealer's Rage makes him immune to all of Tinker's damage and debuffs.
* Lifestealer can infest any mobile hero (teams usually pick one against Tinker), which ensures that Tinker will die if he is caught.

* Feast will deal a large amount of damage to Tiny's large health pool.
* Rage protects Lifestealer from Tiny's magical burst damage.

* Death Ward does little damage against Dragon Knight's armor, and Dragon Knight's high health regeneration minimizes damage from Maledict.

* The lifesteal of Feast scales accordingly to the health of its target, which is effective against Pudge due to his high health and further health granted by stacks of Flesh Heap.
* Lifestealer can activate Rage to completely negate magic damage, therefore rendering the damage of Rot and Dismember null.
* Pudge's plentiful health makes him an ideal target for Open Wounds.

* Rage provides spell immunity to Lifestealer and thus nullifies all of Lion's abilities.
* Open Wounds allows Lifestealer to easily catch Lion out and prevent him from escaping.

* Rage protects Lifestealer from all of Lina's abilities (except an upgraded Laguna Blade).
* Open Wounds is great to keep Lina in place because she has no abilities to help her escape.

* Lifestealer's Rage lets him clear Remote Mines and Proximity Mines with proper vision.
Additional:
* Rage protects Lifestealer from all of Techies' magic damage and disables and dispels Stasis Trap's debuff .
* Usually teams will have a hard time pushing high-ground against Techies, but Lifestealer can just pop Rage and walk uphill without fear of Techies.

* Feast is an effective tool against Centaur Warrunner, who generally has high health and low armor, and compensates the reflected damage of Retaliate.
* If activated, Rage protects Lifestealer from Hoof Stomp, Double Edge, and Stampede.

* If Silencer can't prevent Dragon Knight from using Elder Dragon Form, Silencer's spells aren't going to be that effective against him, as Dragon Knight relies on right-clicks and not spells.
* Dragon Blood's armor bonus and health regeneration allows Dragon Knight to stay in the lane against Glaives of Wisdom.
* Dragon Knight often builds Black King Bar, allowing him to remove Global Silence before engaging.

* Feast deals damage and heals Lifestealer based on the target's maximum HP, which is greatly effective against naturally high HP heroes such as Doom.
* Rage allows Lifestealer to become spell immune to negate the magical damage of Infernal Blade and Scorched Earth.
* Doom has no effective means of escape from Open Wounds. This is particularly devastating in lane, where Doom may have to play a much more passive, conservative play style as a result.

* Rage can be used to escape from a Glimpse and to move out of Kinetic Field.
* Infest allows Lifestealer to dodge Glimpse.

* Leshrac's high magic damage is ignored by Rage.
* Lifestealer can get in Leshrac's face with Rage and mitigate any other damage taken by Leshrac with Open Wounds.

* Feast's lifesteal makes it nearly impossible for Axe to initiate and bring Lifestealer's health low enough for Culling Blade, even with many procs of Counter Helix.
* Feast's damage is calculated as a percentage of health, turning Axe's high health against him. This allow Lifestealer to hit Axe much harder than most other heroes.
Additional:
* Feast makes it impossible to put Lifestealer's health for a Culling Blade and also deals high damage to Axe due to his naturally high health.
* However, Lifestealer's Rage can be pierced by Berserker's Call.

* Rage prevents Earthshaker from damaging and stunning Lifestealer.
* Feast is very effective against Earthshaker, because of him being a strength hero, allowing Lifestealer to heavily harass and kill him.
* Open Wounds prevents Earthshaker from escaping after he initiated.
* Infest gives Lifestealer an easy way to escape should he get caught out by Earthshaker.

* Rage protects Lifestealer nearly from all of Invoker's spells.
Additional:
* Rage grants immunity from Invoker's spells and can dispel most of the disables such as the armor loss from Forge Spirit and the constant stuns of Cold Snap.

* Dragon Knight's high natural sustain and health regeneration from Dragon Blood makes him hard to take down in Duels.

* Rage grants Lifestealer immunity to all of Jakiro's spells. Note: magic resistance will not dispel the attack speed slow effects from Dual Breath and Liquid Fire.

* Dragon Knight can simply tank and destroy all Shadow Shaman's Serpent Wards.

* Spirit Breaker's slow attack speed and moderate damage do very little to harm Dragon Knight, even if ganked with Charge of Darkness.

* Feast is good against high health strength heroes such as Alchemist.
* Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.

* Lifestealer excels at killing high health heroes with Feast, and Sven is no exception.
* Rage stops Storm Hammer from hitting Lifestealer.
* Rage and Open Wounds helps Lifestealer survive against Sven's high physical damage.

* Ogre Magi has nothing against Rage and his high health pool amplifies Feast.
Additional:
* Lifestealer's Rage makes him immune to all of Ogre's magical debuffs and also dispels them.
* Ogre's as hero with great durability and high health is great target for Lifestealer in any stage of the game, thanks to Feast.

* Rage protects and dispels all of Dark Willow's abilities.
Additional:
* Rage protects Lifestealer from all of Dark Willow's abilities.

* Bloodseeker's physical damage is unlikely to kill Dragon Knight, and therefore rarely get a chance to recover the large amount of HP from Bloodrage.

* With Feast and Rage, Lifestealer is nearly impossible for Clockwerk to bring down, and is the last hero Clockwerk wants to be trapped with in Power Cogs.

* Rage is very useful against Zeus, as it negates magic damage and provides spell immunity. In addition, the increased attack speed can tear Zeus apart in combination with Open Wounds.
* Lifestealer can avoid Thundergod's Wrath with Infest.

* Durable heroes can fight with stand against Tusk during 1v1: Axe, Dragon Knight, Night Stalker, Centaur Warrunner, Wraith King and more.

* Heroes that rely on physical damage are ineffective against Dragon Knight due to his high armor: Phantom Assassin,Bloodseeker, Lifestealer, Troll Warlord

Additional:
* High armor thanks to Dragon Blood makes it difficult for Phantom Assassin to burst down Dragon Knight, as she deals 100% physical damage.
* Dragon Tail stuns Phantom Assassin as soon as she initiates, preventing her from gaining bonus attack speed.
* Dragon Knight is one of the few heroes who can safely solo lane against Phantom Assassin alongside a support.

* Heroes with spell immunity-granting spells will render Phoenix useless against them, as Phoenix has almost no spell immunity-piercing ability, other than the stun at the end of Supernova: Lifestealer, Juggernaut.

* Lifestealer with Rage and Infest
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Juggernaut and Lifestealer have abilities (Blade Fury and Rage respectively) that prevent Crystal Maiden from using her spells on them in the early game, before Black King Bar and other magical reduction is even an issue.

* Heroes with high armor and/or durability can handle Juggernaut's ultimate, such as Sven and Dragon Knight.

* Heroes that are hard to gank: Dragon Knight, Mars, Centaur Warrunner.

* Slark, Lifestealer, Morphling and such with a good escape mechanism are a nuisance to deal with in the early-game.

* Rage ignores all of Gyrocopter's magical attacks.
* Open Wounds makes it hard for Gyrocopter to get away.
* Feast helps Lifestealer out-damage Gyrocopter at close range.

* Despite the armor reduction from Meld, Templar Assassin's reliance on physical damage and medium attack speed is unlikely to harm Dragon Knight.
* Templar Assassin's Refraction charges also get quickly removed by the damage over time from Dragon Knight's ultimate.
Additional:
* The damage over time from Dragon Knight's Elder Dragon Form rapidly burns down Refraction, allowing him to attack her. Also, Breathe Fire reduces Templar Assassin's damage and Dragon Tail is a stun with a considerable duration, letting him and his team whittle her health down once her defenses wear off.

* Rage renders Lifestealer immune to the damage from Burning Spears and Life Break.
* Feast and Open Wounds makes Lifestealer one of few heroes that can outlast Huskar in a one-on-one fight.

* Heroes with spell immunity or pseudo-blinks which provide invulnerability: Lifestealer, Juggernaut, Omniknight, Huskar , and Tusk have spells which allow them to easily escape Dream Coil.

* Breathe Fire and Elder Dragon Form's splash damage takes out Phantom Lancer's illusions quickly.
* If Dragon Knight can Dragon Tail the real Phantom Lancer, he and his team can quickly kill him before he has a chance to escape.

* Lifestealer is not affected by Earthbind or Poof during Rage, making him a difficult target to work around.

* Cleave heroes will clear her illusions. Such heroes include Sven, Magnus, Dragon Knight in Elder Dragon Form, Ember Spirit (via item), Phantom Assassin (via talent or item), etc.

* Rage ignores all of Viper's magical damage.
* Feast and Open Wounds combine to heal through Viper's physical damage.

* Dragon Blood's armor bonus greatly reduces the damage dealt by Phantasm.
* Breathe Fire and Elder Dragon Form's splash damage quickly destroy illusions and reduces their damage output.

* Dragon Knight's insanely high armor and splash damage can cause Lycan to struggle taking him down.

* Heroes with magic immune abilities can negate most of Visage's attacks like Pangolier and Lifestealer.

* Riki does little damage to Dragon Knight, as he relies only on physical damage with modest attack speed and lack of burst.

* Broodmother's spiderlings and spiderites do almost nothing against Dragon Knight.

Additional:
* Breathe Fire will clear Broodmother's spiderites while significantly damaging her spiderlings and decreasing their damage output.
* Dragon Blood's added armor and regen mitigates the damage done by Broodmother and her spiders.
* Elder Dragon Form at level 2 and above applies splash damage to Dragon Knight's auto attacks.

* In general, heroes with spell immunity abilities won't be caught inside by Pit of Malice: Juggernaut, Lifestealer.

* The extra damage from Searing Arrows is largely blocked by Dragon Knight's armor.