* Alchemist's reliance on fast attack speed to do single-target damage makes him vulnerable to Static Link. It also goes through Black King Bar, which is a standard item on Alchemist.
* Eye of the Storm is great against high health strength heroes as it reduces their survivability to physical damage.
* Razor has early lane push to counter Acid Spray.

* Static Link 's damage instants fully ignore Untouchable, combine with Eye of the storm and high movement speed compare to Enchantress with no mobility, Razor can easily take away her squishy health pool.

* Heroes that can jump on her: Slark, Queen of Pain, Anti-Mage

* Shadow Dance allows Slark to not be targeted by Unstable Concoction, making Alchemist stun himself and making himself vulnerable to the enemy.
* Dark Pact also allows him to just purge off the stun if timed correctly.
* Essence Shift will steal stats over long durations at a time should Alchemist lack the damage to kill Slark.

* Skywrath Mage can easily harass Alchemist in the laning phase with multiple Arcane Bolts. Additionally, if Alchemist is in the process of throwing an Unstable Concoction, and has no way to dispel Ancient Seal, the self stun becomes an easy set up for Mystic Flare.
* Caution, however, as a decently farmed Alchemist with {Item ID:Radiance} and {Item ID:Manta Style} can easily send illusions to harass and force Skywrath Mage out.

* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage

Additional:
* Untouchable is useless versus constant Arcane Bolts, and it doesn't help that her strength gain is the lowest in the game.
* A jungle Enchantress can weaken lanes and make Skywrath Mage's job easier.
* The magic amplification from Ancient Seal makes her even squishier to Skywrath and his allies' magic nukes.

* Alchemist is a well-known Radiance carrier among other auras your illusions will benefit from. They also get the extra move speed and reduced base attack time from his Chemical Rage, and it's even better if you can catch him as his own rage is about to expire.
* Disruption will buy enough time for all allies to retreat when Alchemist starts to activate Unstable Concoction.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.

* Amazingly, Enchantress has even lower health than Pugna. Though she does pack quite a punch through Impetus, she can't use it if she is under Decrepify.
* Pugna's Magical DPS is way greater than the heal from Nature's Attendants, which will also harm her quite a bit if she's next to Nether Ward.

* Pugna's Decrepify makes sure that either Alchemist is unable to hit anyone while also being slowed and susceptible to magical damage, or can protect an ally from physical attacks. Besides, Pugna can push early on, when Alchemist is not strong enough to repel it, so by the time Alchemist comes online, he might be forced to sit in base.

* Melee heroes with low mobility can be kited and killed by Viper: Treant Protector, Kunkka, Alchemist, Troll Warlord, Wraith King, Tiny, Sven.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.

* Riki usually buys Diffusal Blade to initiate, which renders Enchantress' movement speed useless, and is usually followed with Smoke Screen.
* Riki can effectively hit Enchantress by Tricks of the Trade alongside with Diffusal Blade and Smoke Screen's initiation. For a hero like Enchantress, 3 to 4 hits from Riki is a big deal, unless Enchantress built Force Staff earlier.

* Magnetic Field makes Impetus miss; if Enchantress decides to enter the field, she is giving up bonus damage since Impetus deals greater damage at higher distance away from targets.

* Vendetta breaks Untouchable and deals great damage against her.
* Enchantress' lack of mobility makes her a primary target for ganking with Vendetta.
* Spiked Carapace can reflect Impetus and stun Enchantress.
* Mana Burn can deal tremendous damage against her due to being an Intelligence hero.
Additional:
* Spiked Carapace reflects the damage from Impetus.
* Enchantress is a rather squishy hero, making her fall easily to Nyx Assassin's high burst damage.

* Corrosive Haze followed by Slithereen Crush takes advantage of Alchemist's main weakness, being physical damage before he has the change to improve his surviability with items.
* Bash of the Deep will deal lots of damage during the laning phase.

* Untouchable doesn't work against Unleash, as Marci gains 1000+ attack speed for the fury combo.
* Enchantress' low health makes her a fragile target for Marci's damage blasts.
* Marci can use Rebound on one of her enchanted creeps to easily reach the Enchantress and negate the bonus damage dealt by her Impetus. It helps that most of her best creeps have a low attack range, creating a makeshift bridge towards their master.

* Blade Fury dispels the slow from Enchant, spell immunity and used to burst her down during the early laning stage.
* Omnislash and Swiftslash's physical damage burst ignore Untouchable.
* Silver Edge is an ideal item for Juggernaut to deal with Untouchable, making her vulnerable to melee attacks.
Additional:
* Blade Fury dispels the slow from Enchant, and can burst Enchantress down during the laning stage.
* Omnislash and Swiftslash's physical damage burst ignore untouchable.
* Silver Edge is a common item for Juggernaut for dealing with Untouchable.

* Untouchable won't mitigate Venomancer's magical damage, and Enchantress is vulnerable to magic damage.
* Both Venomous Gale and Poison Nova lowers the amount of healing received by Enchantress and her allies from Nature's Attendants.

* Enchantress has a very low health pool, allowing Zeus to burst her down quickly before she can heal off the damage.
* Zeus will not be affected by Untouchable, as he won't try to attack her with right clicks anyway.
* Zeus can stay out of her attack range while trying to kill her, especially if he has bought an Aether Lens.
* Most heroes would want to get on top of Zeus to kill him, but Enchantress does not have this option as doing so would severely limit her Impetus damage.
* The exception is the laning phase, where Enchantress can gank Zeus if she Enchants a good creep.

* Ice Blast nullifies the health regeneration granted by Chemical Rage, which Alchemist greatly relies on to stay alive in battle.
* Alchemist tends to build Armlet of Mordiggian which can be deadly during Ice Blast.
Additional:
* Ice Blast cancels out Chemical Rage's rapid health regeneration. It can also take advantage of Alchemist's Armlet of Mordiggian toggling, as it will make HP drain insanely fast, essentially killing the bearer in no time.

* Battle Trance and Fervor can help cancel out Untouchable.
Additional:
* Untouchable's attack speed slow is easily remedied by Fervor stacks and Battle Trance.
* Troll Warlord is a natural Silver Edge carrier, disabling Enchantress' Untouchable.

* Quas-Exort Invoker can win the mid lane easily against Alchemist because Quas regeneration will nullify Acid Spray's damage over time and Exort damage bonus will allow Invoker to out last hit Alchemist.

* Axe can force Alchemist to attack him with Berserker's Call. High attack speed from Chemical Rage will cause Counter Helix to proc multiple times.
* This can get worse if axe has Blade Mail, which then returns all damage to Alchemist himself.
* Axe's abilities can pierce through Black King Bar, which is a common item for Alchemist.
* Berserker's Call grants Axe a huge bonus armor, which greatly counters Alchemist's physical damage for the most part.

* Windrun's speed allows easy pursuit or escape, while the evasion greatly reduces the threat of Enchantress's Impetus, especially when retreating.
* Shackleshot is a powerful disable if Enchantress gets too close to one of her own minions.
* Focus Fire can negate Untouchable.

* Enchantress has pitiful health, and cannot tank Lina's heavy magic damage.
* Untouchable is decently countered by Fiery Soul, exposing Enchantress' weakness to physical damage due to her low armor.
* Lina is decent at clearing creeps and can kill Enchantress' creeps quickly.
Additional:
* Enchantress has a very small health pool and cannot tank Lina's heavy magic burst.
* Untouchable is decently countered by Fiery Soul, exposing Enchantress' weakness to physical damage due to her low armor.
* Lina is decent at clearing creeps and can kill Enchantress' creeps quickly.

* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.

* Tidebringer will deal lots of damage to Alchemist before he builds physical survivability items.
* Torrent and X Marks the Spot can control Alchemist at all stages of the game before he has Black King Bar.
* Ghostship's rum buff will greatly reduce the Alchemist's damage output in teamfights including his Radiance.

* Reaper's Scythe can kill Alchemist before Chemical Rage has the time to heal him.
* Ghost Shroud can prevent Alchemist from attacking Necrophos, as well as make him immune to Acid Spray and Unstable Concoction damage.
* Heartstopper Aura will do damage as long as Necrophos is alive based on health percentage, which is a problem for a strength hero such as Alchemist.

* Untouchable won't mitigate magic damage, and a squishy Enchantress is very vulnerable to Queen of Pain's magic burst.

* Enchantress is very fragile without any form of magic resistance, allowing Lion to easily burst her down.
* Nature's Attendants is a slow heal, making it ineffective against Lion's burst.
* Enchantress lacks any escape mechanism apart from her raw movement speed, allowing Lion to disable her.
* Since Lion's damage comes mostly from his skills, Untouchable does nothing to mitigate it.

* Visage can quickly kill heroes with low to medium base armor and no innate escape mechanism. Examples include Alchemist, Crystal Maiden and Zeus.

* Any hero with a low HP pool is easy for Tinker to nuke down: Crystal Maiden, Enchantress, Gyrocopter, Lion, Riki, Techies, Terrorblade, Necrophos, Invoker.

* Heroes that can jump on her: Slark, Queen of Pain, Anti-Mage

* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage

* Heroes with haste can negate Enchant's slow: Weaver, Dark Seer, Lycan, Centaur Warrunner.

* Heroes like Enchantress and Chen, or heroes that make use of Helm of the Dominator are weak to Crystal Maiden, as Frostbite can do wonders against Enchant, Holy Persuasion, or dominated creeps. Careful though, as an army of carefully controlled creeps (Enchantress and Chen) can hold many stuns that will cancel Freezing Field.

Additional:
* Frostbite does 1000 magical damage to Enchantress's creeps and roots them for 10 seconds, which hinders her ability to gank.

* Heroes with little health or magic resistance are easily picked off with Oracle's magic burst, such as Skywrath Mage, Crystal Maiden, or Enchantress.

* In general, attacks of the melee heroes who are entirely reliant on dealing physical damage and/or have very little to no area-of-effect abilities will make Underlord tickle and will have no effect against him, and will be unable to ambush Underlord and his team if Underlord chooses to use Dark Rift to get to a designated point of the map: Phantom Assassin, Terrorblade, Troll Warlord, Drow Ranger, Phantom Lancer, Chaos Knight, Sven, Wraith King, Bounty Hunter, Alchemist, Templar Assassin, Nyx Assassin, Bane.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.

* Heroes with haste can negate Enchant's slow: Weaver, Dark Seer, Lycan, Centaur Warrunner.

* Heroes with nukes that can jump her: Clockwerk, Snapfire, Spirit Breaker, Techies

* Heroes with haste can negate Enchant's slow: Weaver, Dark Seer, Lycan, Centaur Warrunner.

* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage

* Sand King is a strong ganker, allowing him to shut down squishy heroes in the early game: Phantom Assassin, Clinkz, Sniper, Enchantress,...

* Heroes who rely on skills to become a heavy hitter in a certain amount of time can waste their timing because of a lucky Lucky Shot's disarm: Terrorblade, Sven, Clinkz, Windranger, Alchemist, Dragon Knight, Legion Commander

* Heroes with nukes that can jump her: Clockwerk, Snapfire, Spirit Breaker, Techies

Additional:
* Techies does huge amounts of magical damage, which will bypass Untouchable.
* Enchantress depends on abilities to do damage and heal, which Blast Off's silence prevents.

* Melee heroes that get kited easily have hard times dealing with Puck without any lockdowns, as Puck is one of the most mobile heroes. Heroes like Sven, Lifestealer, Ursa and Alchemist may have problems to get to Puck without proper initiation items. They also lack reliable lockdowns, as their disables are easily avoidable for Puck, or are just a soft disable.

* Heroes with nukes that can jump her: Clockwerk, Snapfire, Spirit Breaker, Techies

* Meepo can quickly kill Enchantress with a Poof combo, rendering Untouchable useless.

* Though Enchantress's Untouchable can greatly reduce Luna's attack speed, and can go through any form of Spell Immunity, she has a pitiful HP so Lucent Beam and Eclipse can kill her very quickly.
* Moon Glaives allows Luna to clear Enchantress's creeps very efficiently.
Additional:
* Enchantress has pitiful HP, even more pitiful than Luna, so Lucent Beam and Eclipse will often harass and/or kill her through her Untouchable.
* With Moon Glaives, Luna can clear Enchantress's creep wave efficiently.

* The burst damage from Timbersaw's abilities is more than enough to deal with Enchantress and her creeps.
* Timbersaw doesn't rely on his physical attacks, which makes Untouchable useless against him.
* Timber Chain can close the gap between them and minimize damage from Impetus.
* Be aware, however, that Timber Chain could work against him if used to escape.
* However, Impetus can ignore Reactive Armor if Enchantress is not a primary target for Timbersaw or if he is disabled.