* Time Walk could be used to close the distance within Drow Ranger, hindering her Marksmanship bonus.
* Faceless Void could lock down Drow Ranger with Chronosphere before she has the chance to retaliate due to her low health pool.

* Shapeshift allows Lycan to get close and disable Marksmanship.
* Shapeshift also makes him immune to slows like Drow Ranger's Frost Arrows.
Additional:
* The Wolves' speed causes the knockback from Gust to be ineffective.
* She lacks escapes and loses her Marksmanship when someone is near her. Lycan takes advantage of these weaknesses.

* Heroes with summons: Lycan, Broodmother, Visage.

* Chronosphere provides excellent lockdown against Rage.
* Faceless Void's Time Lock stops Lifestealer from getting health regeneration from auto-attacks

* Time Dilation can limit Zeus to casting his abilities only once in a fight, effectively serving as a 6/8/10/12 second silence.
* Time Walk negates Zeus's burst damage.
* Chronosphere makes Zeus the best target for Void because of his low mobility.

* Zeus can deal a huge amount of damage, but he lacks defensive abilities, such as good mobility or resistance. Due to that, he doesn't like to be touched by any means. Heroes with higher damage output and good mobility will often get easily near Zeus and trade damage (eventually causing Zeus's downfall). Such Heroes include: Lycan, Slark, Storm Spirit, Spectre and others.

* Mirana's Leap is ineffective if Lycan uses Shapeshift. It also allows him to dodge Sacred Arrow.
* As a natural Necronomicon carrier, he can reveal Mirana and her allies hiding in Moonlight Shadow and the Necronomicon Warrior can kill Mirana from an unintentional Sacred Arrow or Starstorm upgraded with Aghanim's Scepter.

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Lycan is a common Necronomicon 3 carrier, hindering his attempt of initiate or escape using Vendetta.
* And the Last Will can be killed quickly with Nyx Assassin's high burst damage, although he can at least partially counter it with a well-timed Spiked Carapace.
* Lycan's high HP easily shrug off Nyx Assassin's burst damage and fend him off.

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Hard lockdowns such as Chronosphere can end a Puck's life quickly. A Puck stunned for longer than 3 seconds usually ends up dead.
* As the type of hero that spams spells, Time Dilation counters Puck very effectively. Phase Shift is Puck's main ability for survivability, and Time Dilation effectively triples its cooldown.
* If not silenced, Time Walk can easily undo the damage dealt by Illusory Orb, Dream Coil and Dagon.

* A Lycan with Shapeshift can always run down Puck and kill him very quickly due to his low armor. It is important to abuse as many cliffs and trees as possible to escape from a Lycan.

* Faceless Void's Timewalk allows him to backtrack any damage taken from Techies' mines. Also, he can kill Techies easily with his Chronosphere and Time Lock, preventing them from suicide. Chronosphere also reveals Remote Mines and Stasis Traps in its radius.

* Heroes with summons like Broodmother,Enigma, Invoker, Nature's Prophet, Lycan, Visage;or illusions, like Naga Siren, Phantom Lancer, Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity mines in the early game.

Additional:
* He can send wolves to defuse Proximity Mines, and he can catch up Techies and kill him before they can deny themselves. Even if the suicide is successful, Lycan can still survive because of his tankiness.

* You can easily kill a squishy Sniper, due to your high movement speed and his lack of escape.

* Frail heroes who lack mobility can also be an easy target to lock down with Chronosphere, such as Drow Ranger, Luna, Sniper, Terrorblade.

* Heroes with low armor and little mobility, like Huskar, Io, etc. will also have an unfortunate fate.

* Carries that can out damage Huskar will do well against him: Legion Commander, Faceless Void, Troll Warlord, Phantom Assassin.

* The movement speed granted from Shapeshift means that Spectre has no way to punish Lycan if he wants to splitpush or pick off supports. Furthermore, he will kite Haunt and cannot be slowed by Spectral Dagger.
* As Lycan typically has Summon Wolves out and builds Necronomicon, very rarely will he be damaged by Desolate if he does manage to get into a fight against her.
* Lycan is often part of an early game push strategy which is often the best counter to Spectre because she needs a lot of time and space to come online as a late game carry.

* Time Walk will easily backtrack Lina's burst damage (especially Laguna Blade) if not timed correctly.
* During Chronosphere, squishy heroes like Lina will be main target of Faceless Void in his ultimate.

* Time Dilation, while Spell Steal with Aghanim's Scepter is on cooldown will make it unusable for a long time, reducing Rubick's potential.
* Rubick's own Chronosphere stolen with Spell Steal cannot stun Faceless Void.

* Time Dilation affects Morphling's low cooldown spells, making them unusable for a long time, rendering Morphling nearly useless.
* Morphling cannot use Attribute Shift while he is inside Chronosphere which makes it easy to kill him.

* Time Walk makes it hard for Gyrocopter to pin down Faceless Void. With Backtrack it also negates most of his attacks.
* Time Dilation will prevent Gyrocopter from using his cooldown spells.

* Time Dilation affects Queen of Pain's low cooldown abilities, making them unusable for a long time, rendering Queen of Pain nearly useless.
* Chronosphere provides excellent lockdown against Queen of Pain, allowing for reliable kills in all stages of the game.
Additional:
* Time Walk and Backtrack allows Faceless Void to easily negate Queen of Pain's burst damage.
* Chronosphere prevents Queen of Pain from escaping with Blink, and her low survivability makes her an easy kill.
* Time Dilation will prevent Queen of Pain from using her low-cooldown spells or force her to buy Black King Bar or a Eul's Scepter of Divinity to dispel the debuff and re-engage.

* Time Walk allows Faceless Void to escape or enter Arena Of Blood, and helps him recover from Mars' burst damage.
* Time Lock's magical damage ignores Bulwark.
* Chronosphere allows Faceless Void to reposition behind Mars, ignoring his Bulwark while he is helplessly frozen in time.
Additional:
* Time Dilation while Spear of Mars and God's Rebuke are on cooldown will make these abilities unusable for a long time, rendering Mars nearly useless.
* Mars cannot turn inside the Chronosphere, which makes it easy to attack him from the back, bypassing Bulwark completely.

* Lycan doesn't care much about Lich's slows thanks to Shapeshift.
* Chain Frost can bounce to the wolves that Lycan summons.
Additional:
* Lich possesses a lot of slows, which Lycan doesn't care about when he Shapeshifts.
* Lich has no in-built escape, which makes him a good target for Lycan.

* Time Dilation while Death Pulse and Reaper's Scythe are on cooldown will make these abilities unusable for a long time, rendering Necrophos nearly useless.
* Necrophos cannot use Ghost Shroud while he is inside Chronosphere which makes it easy to kill him.

* Shapeshift is useful for killing or escaping Silencer.
* Summon Wolves, and later Necronomicon units, can be used to hunt a badly wounded Silencer down - even when Lycan himself can't fight.

* Time Dilation while Static Remnant and Electric Vortex are on cooldown will make these abilities unusable for a long time, reducing Storm Spirit's potential.
* Faceless Void can catch Storm Spirit during Ball Lightning with a well-timed Chronosphere or Time Walk.

* Time Dilation while Shukuchi and Geminate Attack are on cooldown will make these abilities unusable for a long time, reducing Weaver's escape potential.
* Chronosphere will reveal Weaver during Shukuchi.
Additional:
* The wide range of Chronosphere makes it difficult for Weaver to avoid it with Shukuchi and, once caught, his low survivability makes him an easy kill.
* With no significant source of burst damage, it is easy for Void to survive combat with Weaver using Time Walk.
* Time Dilation will prevent Weaver from using Shukuchi or force him to use Time Lapse to dispel the debuff and re-engage.

* Lycan's ultimate makes him immune to slows from Ursa's Earthshock as well as allowing him to outmaneuver Ursa during Enrage. Lycan can also easily chase down Ursa while shapeshifted, should Ursa try to flee.

* Time Walk can easily avoid Invoker's combo damage if doesn't have disables.
* Chronosphere will reveal Invoker during Ghost Walk.
* All of Invoker's hidden cooldowns are affected by Time Dilation, so Faceless Void can easily slow him down a lot.
Additional:
* Time Dilation prevents Invoker from further invoking for the entire duration of the debuff, as well as massively slowing Invoker based on the large amount of spells he has.
* Time Walk will completely negate Invoker's combo damage.
* If Invoker is caught in Chronosphere, he will most likely be the primary target due to the large teamfight contribution he can provide.

* Shapeshift allows Lycan to escape from Upheaval with 650 movement speed.
* Warlock doesn't have a lot of AoE abilities to deal with Lycan's wolves from Summon Wolves.

* Magnetic Field is useless against melee heroes, so Lycan can attack Arc Warden without missing.
* Flux doesn't affect Lycan that much, because Shapeshift grants immunity to slows and because he is never alone.
* If their Tempest Double has been called, Lycan can still kill Arc Warden before the double expires.

* Time Walk can break Static Link very quickly, preventing Razor from building up attack damage.

* Any hero who can survive Magnus's initiations and manfight him: Huskar, Faceless Void, Weaver, Abaddon, Troll Warlord, Alchemist, Dragon Knight, Night Stalker, Viper.

* Frail heroes who lack mobility can also be an easy target to lock down with Chronosphere, such as Drow Ranger, Luna, Sniper, Terrorblade.

* Heroes with low armor and little mobility, like Huskar, Io, etc. will also have an unfortunate fate.

* Heroes with abilities or items that can silence or disable Anti-Mage for long periods of time will prevent him from Blinking away: Silencer, Shadow Shaman, Grimstroke, Clinkz, Riki, Faceless Void, Skywrath Mage, Puck

Additional:
* Chronosphere provides excellent lockdown against Anti-Mage, allowing for reliable kills in all stages of the game.
* Time Dilation while Blink and Counterspell are on cooldown will make these abilities unusable for a long time, shutting down his mobility and defensiveness.
* Faceless Void's low mana pool makes him a poor target for Mana Void, although he is very vulnerable should Anti-Mage burn all of his mana.

* Heroes who do not have nor rely on passive abilities make Nethertoxin much less effective: Clinkz, Pugna, Nature's Prophet, Dark Seer, Lycan, Tusk

* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.

* Skywrath mage also has a terrible time fighting against anything that isn't a hero. As Mystic Flare only affects heroes, his skills are mostly target-based and he has terrible strength and agility, he can easily be kited or harassed by illusion-based heroes like Chaos Knight and Phantom Lancer, or by Heroes that summon other units like Lone Druid, Lycan and Beastmaster.

* Illusion and heroes with summons are difficult to kill with Chen's single-target offensive spells: Terrorblade, Phantom Lancer, Chaos Knight, Broodmother, Naga Siren, Lycan, Visage. However, Chen can convert enemy summons with Holy Persuasion, as long as they don't bunch up.

* In general, heroes with AoE or long range disables (such as Faceless Void with Chronosphere, Pudge with Meat Hook and Elder Titan with Echo Stomp) hinder Crystal Maiden, preventing her from using Freezing Field to help her team in a fight.

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Heroes with single-target abilities will be overwhelmed by Lycan and his summons: Wraith King, Bane, Phantom Assassin.

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Faceless Void is one of the best heroes against Ember Spirit, providing a lot of ways of dealing with him. Ember Spirit becomes a lot weaker if affected by Time Dilation, as he can no longer spam Sleight of Fist.
* Chronosphere is also a reliable lockdown for Ember Spirit, although it can be evaded sometimes by Activate Fire Remnant. Additionally, Void can easily negate Sleight of Fist damage with Time Walk.
* And finally, Void is a great Diffusal Blade carrier. Not only Manabreak's physical damage not negated by Flame Guard, but it also burns Ember Spirit's mana. That, in turn, prevents him from escaping if he survived Chronosphere.

* Time Walk and Backtrack allow Faceless Void to easily negate Oracle's burst damage.
* Time Dilation is effective against Oracle's low-cooldown spells. Although dispellable with Fortune's End, it can still catch Oracle off guard if Fortune's End is on cooldown.

* Time Dilation is similar to a long duration silence, making Timbersaw useless in team fights, or forcing him to adapt his build.
* Time Walk negates Timbersaw's burst damage.
* Time Lock provides magical damage and lock down, and is effective against both Reactive Armor and Timber Chain.
* In conjunction with Time Lock's magical damage, Chronosphere can destroy Timbersaw before he has time to react, and creates a large obstacle that obstruct's Timber Chain's mobility.

* Chronosphere's large obstacle denies Pangolier the room to roll around during teamfights, as well as wasting his ultimate's duration.

* Time Dilation prevents Bristleback from spamming his low-cooldown abilities, greatly reducing his damage and effectiveness.
* Chronosphere allows allies to resposition and hit Bristleback from the front, bypassing his defensive bonus from behind.
* Bristleback has no way to prevent Faceless Void from using Time Walk.
Additional:
* Time Dilation while Quill Spray and Viscous Nasal Goo are on cooldown will make these abilities unusable for a long time, rendering Bristleback nearly useless.
* Bristleback cannot turn inside the Chronosphere, which makes it easy to attack him from the front, completely bypassing his passive damage reduction.

* Beware of placing the Death Ward if Chronosphere is off cooldown, as it will cancel the effect and leave Witch Doctor vulnerable if he does not react in time.

* Shapeshift allows Lycan to chase down Earth Spirit.

* Time Walk negates Rupture's damage.
* Chronosphere prevents Bloodseeker from running down and picking off weak enemies during teamfights.
Additional:
* Time Walk will not make Rupture deal damage for the distance jumped and can be used to quickly escape from Blood Rite.

* Void's slow is useless against Lycan by activating Shapeshift.
* Night Stalker's single target abilities (with the exception of Void upgraded by Aghanim's Scepter) is not very effective against Lycan's Summon Wolves and Necronomicon minions during the early and mid game.