* Fireblast is a good tool to interrupt Io during its escapes through Tether.
* Ignite can be one of the few spells with enough total damage to out-trade the sustained healing Io provides for its fellow laner.
* However, picking other supports that focus less on the laning phase is generally a better choice against Io.

* Mars has no way to trade with Ogre Magi in the early game thanks to his high base health, resistance and Ignite.
* Once Ogre Magi gets level 2 he may also have Bloodlust, which makes him even harder to deal with in lane.
* Fireblast can be ridiculously strong later on in the game for controlling Mars.
* Spear of Mars, which is Mars' main source of damage in the early game, cannot guarantee kills early on Ogre Magi.

* Snowball can protect Tusk and his teammates from a Spear of Mars stun after an Arena of Blood, and with proper targeting, even bring them out of the Arena. This is especially noticeable in the earlier stages of the game before allies buy Black King Bar and rely on this less. Even during the late-game, Tusk can purchase a Blink Dagger to save allies that are caught before Black King Bars can be used by Blinking in and Snowballing out.
* Tag Team is a constant threat to Mars in-lane, as even with early Bulwark points it deal so much damage and slow that Mars is forced to back off from the lane and play defensively every time the spell is used.
* Worth noting is that Ice Shards can be detrimental to Tusk's own team by creating terrain that Spear of Mars can latch on, though using it conservatively is a good enough solution in most cases.

* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper

* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer

* Berserker's Call forces Mars to face in the direction choosen.
* Counter Helix is a much stronger lane trader than Spear of Mars.

* Charge of Darkness can be used to escape or counter-initiate against a Relocate gank.
* Greater Bash and Nether Strike is devastating due to Io's low armor, and can even knock it away from tethered target.

* Disruptor can always Glimpse back Io or his target after he Relocated nearby.
* Even better, thanks to the indicator on the ground, you can even preemptively drop Static Storm and Kinetic Field on the spot they will relocate to.
* Thunder Strike and Glimpse are also good tools to bring back an Io that Tethered away in the fog of war.
Additional:
* Glimpse directly negates Relocate.

* Grimstroke can catch Io and his ally easily with SoulBind as Io has a tendency to tether himself with an ally frequently.
* Io is highly vulnerable to disables. Hence, Grimstroke's Phantom's Embrace is a great ability to hinder Io's potential.
Additional:
* Soulbind can target both Io and its Tethered ally, allowing Grimstroke and his team to target both with single target spells. Should Io try to Relocate, Phantom's Embrace can stop its channel to prevent escape.

* Solar Guardian can save allies caught inside Arena of Blood

* Arcane Orb's pure damage ignores Mars' Bulwark.
* Astral Imprisonment can be used to stop Mars from being disruptive or save allies from his abilities.
* Sanity's Eclipse deals high damage to Mars, due to his low intelligence.

* Swashbuckle is an auto attack and therefore ignores Mars' Bulwark.
* Shield Crash upgraded with Aghanim is an auto attack and therefore ignores Mars' Bulwark.
* Rolling Thunder makes him immune to magic, making Pangolier able to roll in and out from Mars' Arena Of Blood.

* Bulwark is generally irrelevant against Riki as he primarily deals bonus damage from behind.
Additional:
* Blink Strike gives bonus backstab damage. Along with Tricks of the Trade it completely bypasses Bulwark.

* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper

* Nether Blast, Decrepify and Life Drain deal high magical damage and bypasses Bulwark.
* Nether Ward reduces the amount of abilities Mars can use during fights and forces Mars to be careful about the heavy mana cost of Arena Of Blood.
* Pugna is one of few heroes that can contest Mars' ability to push and defend towers early on.

* Quill Spray is very effective against Io, as it has very low armor and has to stay close to the fight to not break its Tether.

* Ice Blast prevents Io from healing an ally with Tether and prevents healing from Overcharge
* Io is a common Mekansm builder which is useless if he is affected by Ice Blast.
Additional:
* Ice Blast prevents Io from healing the target.

* Mars' own father is a formidable foe because Zeus deals massive amounts of magical damage. The high damage, low cooldown nukes of Arc Lightning and Lightning Bolt combined with the percent health magic damage of Static Field will shred Mars' health because it bypasses Bulwark completely.

* Cold Embrace can render the extra attack speed from Overcharge meaningless.
* Splinter Blast and Winter's Curse are very affective against Io, as it has to stay close to its tethered hero.

* Time Dilation while Spear of Mars and God's Rebuke are on cooldown will make these abilities unusable for a long time, rendering Mars nearly useless.
* Mars cannot turn inside the Chronosphere, which makes it easy to attack him from the back, bypassing Bulwark completely.
Additional:
* Time Walk allows Faceless Void to escape or enter Arena Of Blood, and helps him recover from Mars' burst damage.
* Time Lock's magical damage ignores Bulwark.
* Chronosphere allows Faceless Void to reposition behind Mars, ignoring his Bulwark while he is helplessly frozen in time.

* Burning Spear's magical damage is very troublesome for Mars in the laning stage.
* Life Break's percentage-based magical damage bypasses Bulwark, and can also be used to jump in or out of Arena Of Blood.

* Nethertoxin disables Bulwark entirely, making Mars far less tanky. Using Nethertoxin inside Arena of Blood may discourage enemies from following up with Mars' initiation.
* Rod of Atos is currently common on Viper and keeps Mars in position long enough to be killed.
* Beware that Viper is not very tanky earlier in the game, so positioning against Mars is important since a well-timed Spear of Mars can be the end of Viper.
Additional:
* Nethertoxin breaks the damage block from Bulwark.
* Poison Attack and Viper Strike's slows make it difficult for Mars to contribute to fights due to his low mobility.

* If Mars lanes middle, Shadow Fiend can keep the lane pushed against him.
* Shadow Fiend can go an entirely magical based build, which is very effective against Mars.

* Lightning Storm will usually hit both Io and his Tethered target since both will be close enough for the lightning to jump. It can then be followed up by Split Earth.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and his Tethered target.
Additional:
* Lightning Storm will usually hit both Io and its tethered target since both will be close enough for the lightning to jump.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and its tethered target.

* Storm Spirit's abilities all do magical damage, which can bypass Bulwark.
* Ball Lightning can escape through Arena of Blood and it is easy to dodge Spear of Mars.
Additional:
* Ball Lightning makes it almost impossible to catch Storm Spirit without someone else initiating for you.
* Overload is not reduced by Bulwark and the magical damage spam can wear down Mars quickly.

* Rage, acting as a pseudo-Black King Bar, completely negates Mars' initiation if used in time.
* Feast does damage and heals based on max health, perfect against high-health strength heroes like Mars.
* Infest allows Lifestealer to potentially save allies from Mars' initiation with a quick burst of extra health.

* Dragon Slave deals reliable magic damage during the laning phase against Mars.
* Lina's Eul's Scepter of Divinity and Light Strike Array combo can interrupt Mars from being disruptive for a decent amount of time and leave him vulnerable for follow up stuns.
* Laguna Blade deals massive magical damage, and pure damage with Aghanim's Scepter.

* Rebound allows her to jump in or out of the Arena Of Blood. She can safe her allies from the Arena with Dispose as well.

* Venomancer's poison attacks are all magical damage, ignoring Bulwark.
* Venomancer's multiple slows are especially effective against Mars' low mobility.
* Plague Wards can attack through Arena of Blood.
Additional:
* Venomancer's spells all deal magical damage, ignoring Bulwark.
* Venomancer's multiple slows are especially effective at kiting Mars.
* Plague Wards can attack through Arena Of Blood.

* Decay, Soul Rip and Flesh Golem all deal magical damage which ignores Bulwark.
* Decay reduces Mars' natural strength and therefore his health pool, which is what he relies on to trade effectively in lane.

* Necrophos' largely magical damage completely ignores Bulwark.
* Ghost Shroud protects Necrophos from God's Rebuke but more importantly stops Mars from being a threat in lane.

* Sticky Napalm slows turn rate, making it difficult for Mars to control the direction he is facing to activate Bulwark.
* Flaming Lasso disables Mars while enemies re-position themselves behind Mars to avoid Bulwark.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Destroyer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.

* Heroes that can save their allies can be a big problem for Mars: Dazzle, Omniknight.

* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer

* Ursa is a special mention because despite Bulwark diminishing most of the damage Ursa does, he is quite durable, especially with Enrage, discouraging the aggressive all-in playstyle of Mars; Ursa can simply not target Mars.

* Squishy heroes, usually supports, like Io, Ancient Apparition, Keeper of the Light etc can die instantly from Tiny's magic burst.

* Squishy heroes (Io, Crystal Maiden, Lina...), as Earth Spirit can deal tons of damage with Magnetize.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Heroes with low armor and little mobility, like Huskar, Io, etc. will also have an unfortunate fate.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Kunkka's Ghostship and Torrent disrupt fights in Arena Of Blood.

* Heroes with break abilities: Shadow Demon (with Aghanim's Scepter), Viper.

* Heroes that can save their allies can be a big problem for Mars: Dazzle, Omniknight.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Living Armor can be used to save a hero from a Relocate gank.

* Strafe and Searing Arrows allow Clinkz to quickly kill Io due to its low armor.

* Lich's Chain Frost forces Io to give up providing buff to his ally with Tether or suffer devastating damage with his tethered ally.
* Lich could easily use Sinister Gaze to disable Io from getting away with Tether or Relocate.

* Lucent Beam can cancel Tether and Relocate.
* Moon Glaives and Eclipse make short work of Io and its tethered ally.