* Feast is good against high health strength heroes such as Alchemist.
* Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.

* Quas-Exort Invoker can win the mid lane easily against Alchemist because Quas regeneration will nullify Acid Spray's damage over time and Exort damage bonus will allow Invoker to out last hit Alchemist.

* Lifestealer can close the distance to Sniper by using Infest on a fast or durable creep to tank Sniper's damage.
* Open Wounds and Ghoul Frenzy will reduce Sniper's mobility heavily, and Rage's movement speed bonus helps in closing the gap to Sniper. It also protects him from Assassinate and Shrapnel.
* Infest can dodge an incoming Assassinate.

* Invoker's arsenal of magical spells are troublesome for Sniper who has low HP and high armor, which does not benefit him much against Invoker.
* Besides magical damage, he can be disarmed and repeatedly mini-stunned with Cold Snap, preventing him from reacting.
* Leveling Quas can allow Invoker to lane effectively against Sniper despite right-click harassment.

* Rage renders Lifestealer immune to the damage from Burning Spears.
* Feast makes Lifestealer one of few heroes that can outlast Huskar in a one-on-one fight.

* Quas Exort Invoker has high physical damage in the form of Cold Snap and Forged Spirits that allows him to trade hits with Huskar.
* Although Huskar can dispel Cold Snap with Life Break.
* Sun Strike deals pure damage and pierces spell immunity, and Huskar tends to drain his HP, making him a susceptible target.

* Rage protects Lifestealer from all of Lina's abilities (except an upgraded Laguna Blade).
* Open Wounds is great to keep Lina in place because she has no abilities to help her escape.

* Heroes with long animations can be frequently interrupted with Cold Snap: Earthshaker, Monkey King, Shadow Fiend Lina

* Rage, acting as a pseudo-Black King Bar, completely negates Mars' initiation if used in time.
* Feast does damage and heals based on max health, perfect against high-health strength heroes like Mars.
* Infest allows Lifestealer to potentially save allies from Mars' initiation with a quick burst of extra health.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Feast will deal a enormous amount of damage because of Tiny's huge health pool.
* Rage protects Lifestealer from Tiny's magical burst damage.

* Heroes with naturally low mana can be easily shut down by EMP: Sven, Tiny, Wraith King, Omniknight

* Heroes that can keep Marci for a long time in one place so she can't pursue her targets, like Bane, Lion, Shadow Shaman, Invoker, Disruptor and Kunkka.

* Lifestealer's Rage renders him immune to all of Marci's disables and magic damage for a good duration.
* His passive Feast deals bonus damage based on the enemy's max health and heals for the same amount. As a tanky Strength hero, Marci's own strength will be her undoing as well.

* Rage prevents Earthshaker from damaging and stunning Lifestealer.
* Feast is very effective against Earthshaker, because of him being a strength hero, allowing Lifestealer to heavily harass and kill him.
* Open Wounds prevents Earthshaker from escaping after he initiated.
* Infest gives Lifestealer an easy way to escape should he get caught out by Earthshaker.

* Invoker's EMP is extremely effective against Earthshaker due to his low natural mana.

* Slark, Lifestealer, Morphling and other heroes with good escape mechanisms are a nuisance to deal with in the early phase of the game.

* His Forge Spirit can negate Flux.
* Provided he does a right combo with Chaos Meteor, Invoker can easily burst down Arc Warden (plus his clone if he spawns it.)
* An early Orchid Malevolence can shut down Arc Warden pretty hard, especially when Invoker has a good lane against him if he kills him early on.
* Deafening Blast and Ice Wall limit's Arc Wardens mobility and damage, crippling him greatly.

* Heroes with naturally low mana can be easily shut down by EMP: Sven, Tiny, Wraith King, Omniknight

* Lifestealer deserves a special mention because in a fight to the death with equal farm, his lifesteal will do no where near as much sustain as Gods Strength's damage output. However, Rage means he can always disengage at will if he's quick on the trigger. This is one of those matchups that can really go either way.

* Cold Snap can prevent Timbersaw from using both Timber Chain and Chakram due to the frequent stuns interrupting the lengthy cast animations, as well as stopping him mid-chain. This can negate Timbersaw's attempts to escape or dole out extra ability damage.
* Later in the game, Invoker's heavy magical and pure damage can be difficult to avoid, meaning Timbersaw's armor is less useful.

* Rage provides spell immunity to Lifestealer and thus nullifies all of Lion's abilities.
* Open Wounds allows Lifestealer to easily catch Lion out and prevent him from escaping.

* Invoker can drain Wraith King's mana with EMP, preventing him from reincarnating unless Wraith King has his Aghanim's Shard.
* Even if Wraith King survives and reincarnates, Invoker still has an arsenal of spells to lockdown Wraith King, including an easily setup Ice Wall.
* Tornado applies an area dispel to clear skeletons.
Additional:
* EMP allows Invoker to burn Wraith King's mana to prevent Reincarnation from triggering (only until Wraith King gets his Aghanim's Shard).
* Ice Wall and Cold Snap are particularly crippling for Wraith King as they allow to kite him very effectively, preventing him from dealing melee attack damage.

* Tornado allows Invoker to purge Necrophos's Ghost Shroud, nullifying any benefits he could get out of it
* EMP allows Invoker to burn Necrophos's mana, preventing him from using his abilities constantly

* Ice Wall and Ghost Walk can be used to kite and escape from Viper.
* Chaos Meteor and Sun Strike deal heavy damage and can quickly bring Viper down.
* Cold Snap, Tornado, and Deafening Blast are powerful disables that reduce Viper's effectiveness.
* EMP burns Viper's limited mana pool, reducing his potential poison damage.
* Forge Spirits can melt Viper's armor and reduce his durability.

* Rage ignores all of Viper's magical damage, although Viper Strike can pierce spell immunity and slows him down.
* Feast and Open Wounds from Aghanim's Shard can be combined to heal through Viper's physical damage.

* Rage protects Lifestealer from all of Techies' magic damage and disables and dispels Reactive Tazer's debuff .
* Usually teams will have a hard time pushing high-ground against Techies, but Lifestealer can just pop Rage and walk uphill without fear of Techies.
Additional:
* Lifestealer's Rage lets him clear Proximity Mines without taking damage, and allows him to hit heroes whom Techies has used Reactive Tazer on.

* Rage protects Lifestealer from all of Dark Willow's abilities.
Additional:
* Rage protects and dispels all of Dark Willow's abilities.

* Lifestealer's Rage makes him immune to all of Ogre's magical debuffs and also dispels them.
* Ogre's as hero with great durability and high health is great target for Lifestealer in any stage of the game, thanks to Feast.
Additional:
* Ogre Magi has nothing against Rage and his high health pool amplifies Feast.

* Feast makes it impossible to put Lifestealer's health for a Culling Blade and also deals high damage to Axe due to his naturally high health.
* However, Lifestealer's Rage can be pierced by Berserker's Call, Counter Helix and Culling Blade.

* Rage ignores all of Gyrocopter's magical attacks.
* Feast helps Lifestealer out-damage Gyrocopter at close range.

* Cold Snap allows Invoker to interrupt Charge of Darkness and Nether Strike.
* Tornado's long range can be used to cancel Charge of Darkness.
* Deafening Blast prevents Spirit Breaker from right clicking and thus proccing his Greater Bash.

* Feast deals damage and heals lifestealer based on the target max health. Because Spectre often emphasises on building stat items to increase her HP pool, lifestealer can deal a lot of damage to her and heal himself at the same time.
* Ghoul Frenzy slows target, which is bad for Spectre if she does not have Spectral Dagger ready.
* Spectre cannot response to infest if lifestealer choose to stay inside his high mobility allies to approach the backline. Rage's bonus movement speed and spell immunity make it even more frustrating.

* With Feast and Rage, Lifestealer is nearly impossible for Clockwerk to bring down, and is the last hero Clockwerk wants to be trapped with in Power Cogs.

* The lifesteal of Feast scales accordingly to the max health of its target, which is effective against Pudge due to his high health and further health granted by stacks of Flesh Heap.
* Lifestealer can activate Rage to be spell immune, making Rot deal no damage.
* Pudge's plentiful health makes him an ideal target for Lifestealer's Aghanim's Shard ability, Open Wounds.

* Rage grants Lifestealer immunity to all of Jakiro's spells. Note: magic resistance will not dispel the attack speed slow effects from Dual Breath and Liquid Fire.

* Rage is very useful against Zeus, as it negates magic damage and provides spell immunity. In addition, the increased attack speed can tear Zeus apart in combination with Open Wounds.
* Lifestealer can avoid Thundergod's Wrath with Infest.

* Rage can be used to escape from a Glimpse and to move out of Kinetic Field.
* Infest allows Lifestealer to dodge Glimpse.

* Being a strength hero with a high strength gain means Feast can give her a hard time,especially later in the game.
* However,Starbreaker's physical damage can control him in the laning phase.

* Feast is an effective tool against Centaur Warrunner, who generally has high health and low armor, and compensates the reflected damage of Retaliate.
* If activated, Rage can protect Lifestealer from Hoof Stomp, Double Edge, and Stampede.

* Leshrac's high magic damage is ignored by Rage.
* Lifestealer can get in Leshrac's face with Rage and mitigate any other damage taken by Leshrac with Open Wounds.

* Rage will dispel Laser's blind and turns him spell immune for the duration so Tinker cannot damage him.
* Feast will quickly bring down Tinker due to being so fragile.
Additional:
* Lifestealer's Rage makes him immune to all of Tinker's damage and debuffs.
* Lifestealer can infest any mobile hero (teams usually pick one against Tinker), which ensures that Tinker will die if he is caught.

* Heroes that can gain vision over trees to catch Tinker: Invoker, Shadow Demon, Batrider

Additional:
* Tinker is relatively helpless against Invoker, as his Rearm and Boots of Travel can be easily interrupted by Invoker's long range disables, even if he blinks away.

* Tornado dispels Heavenly Grace and Guardian Angel from multiple targets.
* Guardian Angel is generally useless against Invoker as he primarily relies on magical damage.
* EMP depletes Omniknight's already small mana pool.
* Invoker's many disables keep Omniknight's team occupied until Guardian Angel times out.

* Heroes who have most or all their abilities (damage or disable) unable to pierce spell immunity: Keeper of the Light, Lina, Lion, Zeus.

Additional:
* Rage allows him to be immune to all of Ezalor's abilities. Also, the increased movement speed combined with the slow from Ghoul Frenzy and the squishy nature of Ezalor allows Lifestealer to take him down very quickly.

* Heroes with burst damage of their own won't be afraid to go toe to toe with Void Spirit, like Ursa, Lifestealer, or Axe.

* Special mention to Lifestealer as he has magic immunity in Rage which protects agaisnt Primal Beast. However, if he doesn't use it the long chain stun potential can be deadly, denying him to use Feast for a lengthy time.

* Heroes with spell immunity-granting spells will render Phoenix useless against them, as Phoenix has almost no spell immunity-piercing ability, other than the stun at the end of Supernova: Lifestealer, Juggernaut.

* Heroes whose abilities can affect multiple enemies at once: Lina, Luna, Jakiro, Leshrac, Invoker, Lina

* Some heroes with extreme range, like Zeus, Invoker or Clockwerk, can snipe your allies from anywhere after your Grave has expired.

* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: Lifestealer, Doom, Mirana, Clinkz.

* In general, heroes with spell immunity abilities won't be caught inside by Pit of Malice: Juggernaut, Lifestealer.

* Juggernaut and Lifestealer have abilities (Blade Fury and Rage respectively) that prevent Crystal Maiden from using her spells on them in the early game, before Black King Bar and other magical reduction is even an issue.

* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.

* Lifestealer is not affected by Earthbind or Poof during Rage, making him a difficult target to work around.

* Invoker's multiple spells can lock down Undying and disable him from doing much.

* Cold Embrace is the perfect setup for all his nukes - Chaos Meteor, EMP and especially global Sun Strike.

* Invoker's spells will disable and destroy Legion Commander while she's locked in a Duel.

* With Aghanim's Scepter upgraded Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.

* Heroes who can summon illusions and summons because Terrorblade has no abilities to deal with multiple enemies at once outside Reflection: Shadow Shaman, Naga Siren, Broodmother, Lycan, Enigma, Chaos Knight, Phantom Lancer, Shadow Demon, Dark Seer, Nature's Prophet, Invoker, Morphling, Grimstroke with Aghanim's Scepter.

* Heroes with built-in spell immunity can become immune to all of Outworld Destroyer's spells: Lifestealer's Rage and Juggernaut's Blade Fury.

* Any heroes with high intelligence, such as Invoker and Pugna.

* Heroes who can clear the waves of Enigma's Eidolons: Lina, Luna, Dawnbreaker, Jakiro, Shadow Shaman, Death Prophet, Keeper of the Light, Invoker, Keeper of the Light, Puck.

* Enigma lack burst damage, and that makes him vulnerable to heroes who can recover themselves and turn the fight around to their advantage after Enigma finishes his initiation: Faceless Void, Terrorblade, Ursa, Weaver, Broodmother, Slark, Abaddon, Wraith King, Lifestealer.

* With Aghanim's Scepter upgraded Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.

* Heroes with long animations can be frequently interrupted with Cold Snap: Earthshaker, Monkey King, Shadow Fiend Lina

* Rage negates Kunkka's X Marks the Spot.
* As a strength hero with high strength gain and very little armor, as well as low agility gain, Kunkka is vulnerable to Lifestealer's Feast and Open Wounds.

* EMP allows Invoker to burn Medusa's mana to weaken Mana Shield.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
* EMP is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
* Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
* Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.

* Heroes with spell immunity or pseudo-blinks which provide invulnerability: Lifestealer, Juggernaut, Omniknight, Huskar , and Tusk have spells which allow them to easily escape Dream Coil.

* Feast deals damage and heals Lifestealer based on the target's maximum HP, which is greatly effective against naturally high HP heroes such as Doom.
* Rage allows Lifestealer to become spell immune to negate the magical damage of Infernal Blade and Scorched Earth.
* Doom has no effective means of escape from Open Wounds. This is particularly devastating in lane, where Doom may have to play a much more passive, conservative play style as a result.

* Lifestealer's Rage negates Sand King's spells which do magical damage.

* Heroes with long animations can be frequently interrupted with Cold Snap: Earthshaker, Monkey King, Shadow Fiend Lina

* Lifestealer with Rage and Infest
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Rage completely negates all of Nyx Assassin's abilities except Vendetta, while Open Wounds allow him to quickly close the gap.
* Infest combined with an ancient creep makes Nyx Assassin an easy target with Dust of Appearance or a Gem of True Sight.

* Rage can protect Lifestealer from most of the Silencer's abilities with the exception of Global Silence.
* If Lifestealer can Infest himself on any unit, he can literally avoid being affected by Global Silence.
* Against a carry Silencer, Aghanim's Scepter upgraded Infest can disarm him and allow Lifestealer to attack Silencer from within, even if Silencer is spell immune.
* Open Wounds from Aghanim's Shard can severely slow down Silencer, and allow Lifestealer and his team to heal themselves by attacking Silencer.
Additional:
* Rage can protect Lifestealer from most of the Silencer's abilities with the exception of Global Silence.
* If Lifestealer can Infest himself on any unit, he can literally avoid being affected by Global Silence.
* Against a carry Silencer, Aghanim's Scepter upgraded Infest can disarm him and allow Lifestealer to attack Silencer from within, even if Silencer is spell immune.
* Open Wounds from Aghanim's Shard can severely slow down Silencer, and allow Lifestealer and his team to heal themselves by attacking Silencer.

* Heroes with magic immune abilities can negate most of Visage's attacks like Pangolier and Lifestealer.