* Lifestealer can close the distance to Sniper by using Infest on a fast or durable creep to tank Sniper's damage.
* Open Wounds will reduce Sniper's mobility heavily, and Rage's attack speed bonus helps in taking down Sniper.

* Sniper's low mobility and lack of defensive abilities makes him an easy gank target for the entire game, especially if Blink Dagger is picked up.

* Duel's long duration prevents Nyx Assassin escaping from Vendetta. With Aghanim's Scepter she can also bypasses Spiked Carapace.

* Rage completely negates all of Nyx Assassin's abilities except Vendetta, while Open Wounds allow him to quickly close the gap.
* Infest combined with an ancient creep makes Nyx Assassin an easy target with Dust of Appearance or a Gem of True Sight.

* Press the Attack can dispel Laser's blind while providing great attack speed and health regeneration.
* Once caught in a Duel, Tinker, who completely relies on his spells to be effective, has little chances of survival with his low health pool and armor.

* Rage will dispel Laser's blind and turns him spell immune for the duration so Tinker cannot damage him.
* Feast will quickly bring down Tinker due to being so fragile.
Additional:
* Lifestealer's Rage makes him immune to all of Tinker's damage and debuffs.
* Lifestealer can infest any mobile hero (teams usually pick one against Tinker), which ensures that Tinker will die if he is caught.

* Rage renders Lifestealer immune to the damage from Burning Spears.
* Feast makes Lifestealer one of few heroes that can outlast Huskar in a one-on-one fight.

* Carries that can out damage Huskar will do well against him: Legion Commander, Faceless Void, Troll Warlord, Phantom Assassin.

Additional:
* Life Break is almost suicidal when used on Legion Commander, as it invites an instant Duel and Legion Commander herself is a natural Blade Mail carrier.
* Huskar's low survivability and mostly on low health makes him particularly vulnerable to Legion Commander's high physical damage.

* Rage protects Lifestealer from all of Techies' magic damage and disables and dispels Stasis Trap's debuff .
* Usually teams will have a hard time pushing high-ground against Techies, but Lifestealer can just pop Rage and walk uphill without fear of Techies.
Additional:
* Lifestealer's Rage lets him clear Remote Mines and Proximity Mines with proper vision.

* Heroes with low health will die easily during Duels, and can be farmed for damage in the early game: Crystal Maiden, Lich, Techies, Rubick

* Juggernaut and Lifestealer have abilities (Blade Fury and Rage respectively) that prevent Crystal Maiden from using her spells on them in the early game, before Black King Bar and other magical reduction is even an issue.

* Duel is a great initiation to target Crystal Maiden with, as it prevents her from using Freezing Field or any other abilities and allowing the enemy team to quickly kill her before she can aid her team in a fight.

* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: Lifestealer, Doom, Mirana, Clinkz.

* Chen's fragility and low mobility make him an enticing Duel target.
* Overwhelming Odds and Moment of Courage can take advantage of converted creeps' numbers.
* With enough damage from Duel stacks, Legion Commander can also often kill any of Chen's unfortunate allies before he can use Hand of God.
Additional:
* Chen's frailty and low mobility make him an enticing Duel target.
* Overwhelming Odds and Moment of Courage can take advantage of converted creeps' numbers.
* With enough damage from Duel stacks, Legion Commander can also often kill any of Chen's unfortunate allies before he can use Hand of God.

* Lifestealer's Rage makes him immune to all of Ogre's magical debuffs and also dispels them.
* Ogre's as hero with great durability and high health is great target for Lifestealer in any stage of the game, thanks to Feast.
Additional:
* Ogre Magi has nothing against Rage and his high health pool amplifies Feast.

* Heroes rely on their debuff to control the opponent will have a hard time against Press the Attack: Venomancer, Earth Spirit, Ogre Magi

* Special mention to Legion Commander, as she can lock down Void Spirit for a long amount of time without worrying too much about being killed by him during the Duel.

* Heroes with burst damage of their own won't be afraid to go toe to toe with Void Spirit, like Ursa, Lifestealer, or Axe.

* Lifestealer with Rage and Infest
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Legion Commander with Press the Attack
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Feast is an effective tool against Centaur Warrunner, who generally has high health and low armor, and compensates the reflected damage of Retaliate.
* If activated, Rage protects Lifestealer from Hoof Stomp, Double Edge, and Stampede.

* Duel pierces spell immunity and forces him to attack Legion Commander, making him unable to use Omnislash.

* Feast will deal a large amount of damage to Tiny's large health pool.
* Rage protects Lifestealer from Tiny's magical burst damage.

* Legion Commander can use Press the Attack on an ally to dispel the disable of Dismember. The bonus health regeneration also partially counters the damage of Rot
* Duel can be used on Pudge whilst Rot is active, disabling toggling which may result in a lethal health drain that leaves Legion Commander with a successful duel.

* The lifesteal of Feast scales accordingly to the health of its target, which is effective against Pudge due to his high health and further health granted by stacks of Flesh Heap.
* Lifestealer can activate Rage to completely immune to spell, therefore rendering the damage of Rot null.
* Pudge's plentiful health makes him an ideal target for Open Wounds.

* Duel renders Anti-Mage's escape capabilities with Blink and Counterspell useless. Blade Mail and Moment of Courage work well against Anti-Mage's relatively low health.
* A good initiation from Legion Commander and her team is enough to effortlessly kill Anti-Mage.
Additional:
* Counterspell offer no protection against Duel at all.
* Duel locks down Anti-Mage for a long duration, preventing him from escaping with Blink. One successful Duel initiation is usually enough for Legion Commander's team to kill Anti-Mage.

* Leshrac's high magic damage is ignored by Rage.
* Lifestealer can get in Leshrac's face with Rage and mitigate any other damage taken by Leshrac with Open Wounds.

* Feast's lifesteal makes it nearly impossible for Axe to initiate and bring Lifestealer's health low enough for Culling Blade, even with many procs of Counter Helix.
* Feast's healing is calculated as a percentage of a target's max health, turning Axe's high health against him. This allows Lifestealer to trade against Axe much better than most other heroes.
Additional:
* Feast makes it impossible to put Lifestealer's health for a Culling Blade and also deals high damage to Axe due to his naturally high health.
* However, Lifestealer's Rage can be pierced by Berserker's Call.

* Lifestealer's Rage renders him immune to all of Marci's disables and magic damage for a good duration.
* His passive Feast deals bonus damage based on the enemy's max health and heals for the same amount. As a tanky Strength hero, Marci's own strength will be her undoing as well.

* Press the Attack dispels Flaming Lasso.
* Batrider is unlikely to win a Duel in any stage of the game.

* Rage ignores all of Viper's magical damage, although Viper Strike can pierce spell immunity and slows him down.
* Feast and Open Wounds can be combined to heal through Viper's physical damage.

* Press the Attack dispels Venomous Gale and Poison Sting from Legion Commander or her teammates.
* Venomancer is an ideal target for Duel due to his lack of mobility and low starting health.

* Rage negates Kunkka's X Marks the Spot.
* As a strength hero with high strength gain and very little armor, as well as low agility gain, Kunkka is vulnerable to Lifestealer's Feast and Open Wounds.

* Heroes who have all their abilities (damage or disable) unable to pierce spell immunity: Keeper of the Light, Lina, Lion, Zeus.

Additional:
* Rage allows him to dispel Blinding Light from himself.
* Open Wounds allows him to slow and kill Keeper of the Light.

* Press the Attack can dispel the blind from Blinding Light from a hero.
* Duel can be used to instantly take Keeper of the Light out of a team-fight.

* Feast is good against high health strength heroes such as Alchemist.
* Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.

* Legion Commander's spells are relatively useless to Rubick, as Duel isn't suitable for someone as squishy as Rubick.
* Press the Attack can be useful, but its high mana cost will leave you with little mana.
* Overwhelming Odds only does damage and gives a movement speed bonus, Rubick can't do much with the extra move speed.
* Generally, you will be a prime target for Legion Commander's Duels, as Rubick is relatively frail.

* Drow Ranger's low mobility and lack of defensive abilities makes her an easy gank target in the early to mid-game.
* A Dueling Drow Ranger will lose her precious Marksmanship, reduce her damage output significantly and will more likely lose that Duel.

* Rage ignores all of Gyrocopter's magical attacks.
* Feast helps Lifestealer out-damage Gyrocopter at close range.

* Rage protects Lifestealer from all of Lina's abilities (except an upgraded Laguna Blade).
* Open Wounds is great to keep Lina in place because she has no abilities to help her escape.

* Duel is a great initiation to kill Death Prophet before she can cast Exorcism. Furthermore, Legion Commander often builds Blade Mail and can reflect Exorcism's damage to kill Death Prophet easily.

* Feast deals damage and heals Lifestealer based on the target's maximum HP, which is greatly effective against naturally high HP heroes such as Doom.
* Rage allows Lifestealer to become spell immune to negate the magical damage of Infernal Blade and Scorched Earth.
* Doom has no effective means of escape from Open Wounds. This is particularly devastating in lane, where Doom may have to play a much more passive, conservative play style as a result.

* Rage provides spell immunity to Lifestealer and thus nullifies all of Lion's abilities.
* Open Wounds allows Lifestealer to easily catch Lion out and prevent him from escaping.

* Lion is extremely dependent on his abilities. Silences like Silencer's Last Word, magic resistance like Oracle's Fate's Edict, and dispels like Legion Commander's Press the Attack all make his abilities less effective.

* Rage can be used to escape from a Glimpse and to move out of Kinetic Field.
* Infest allows Lifestealer to dodge Glimpse.

* Rage protects Lifestealer from all of Dark Willow's abilities.
Additional:
* Rage protects and dispels all of Dark Willow's abilities.

* Rage grants Lifestealer immunity to all of Jakiro's spells. Note: magic resistance will not dispel the attack speed slow effects from Dual Breath and Liquid Fire.

* Duels prevents Queen of Pain from using Blink, which may force her to purchase a Linken's Sphere or go for the spell block talent.
* Because Queen of Pain is also not a right-click hero, Legion won't have much difficulties in duels.
* Press the Attack dispels Shadow Strike's debuff.

* Heroes that can disable or silence Silencer for a long time, such as Bane and Legion Commander, can lock down Silencer while their allies put him down.

* Heroes rely on their debuff to control the opponent will have a hard time against Press the Attack: Venomancer, Earth Spirit, Ogre Magi

* Heroes with long lockdowns: Shadow Shaman, Legion Commander.

* Rage protects Lifestealer nearly from all of Invoker's spells.
Additional:
* Rage grants immunity from Invoker's spells and can dispel most of the disables such as the armor loss from Forge Spirit and the constant stuns of Cold Snap.

* Heroes with low health will die easily during Duels, and can be farmed for damage in the early game: Crystal Maiden, Lich, Techies, Rubick

* Rage, acting as a pseudo-Black King Bar, completely negates Mars' initiation if used in time.
* Feast does damage and heals based on max health, perfect against high-health strength heroes like Mars.
* Infest allows Lifestealer to potentially save allies from Mars' initiation with a quick burst of extra health.

* Legion Commander is both good and bad vs Mars, on the plus side she can dispel Spear of Mars with Press the Attack and is a good Silver Edge carrier. However, Mars is not an ideal Duel target, as Bulwark will force her to 1: Buy Silver Edge, and 2: Hit Mars with it before the Duel, allowing a skilled Mars to react, especially with Eul's Scepter of Divinity. In teamfights, Mars will happily draw attention after using his abilities, and tank the Duel with all spells on cooldown.

* Overwhelming Odds's damage stacks with each enemy unit in its radius. If this hits Broodmother and a large number of spiders it can deal significant amounts of damage.
* Moment of Courage has a high chance to proc if Broodmother and all of her spiders are attacking her.
* Duel can keep Broodmother in place long enough for Legion's team to kill her.
Additional:
* Overwhelming Odds is great at killing many stacked up spiderlings, thus giving Legion Commander a large buff.
* Duel is a reliable way to lock down Broodmother, preventing her from running into the treeline.

* Duel makes Bristleback fight Legion Commander face to face, forcing him to take full damage.
* Press the Attack dispels the slow from stacks of Viscous Nasal Goo.
Additional:
* When dueled, Bristleback will have to face Legion head on, not allowing his passive Bristleback to come into effect.

* Rage is very useful against Zeus, as it negates magic damage and provides spell immunity. In addition, the increased attack speed can tear Zeus apart in combination with Open Wounds.
* Lifestealer can avoid Thundergod's Wrath with Infest.

* Slark, Lifestealer, Morphling and other heroes with good escape mechanisms are a nuisance to deal with in the early phase of the game.

* Heroes who rely on summons will see them destroyed easily by Overwhelming Odds: Lycan, Arc Warden, Warlock, Chen

* With Feast and Rage, Lifestealer is nearly impossible for Clockwerk to bring down, and is the last hero Clockwerk wants to be trapped with in Power Cogs.

* Heroes who rely on summons will see them destroyed easily by Overwhelming Odds: Lycan, Arc Warden, Warlock, Chen

* Duel is very effective against Io due to its low health and armor.

* Duel's long duration prevents Terrorblade from swapping his health with Sunder.
* Overwhelming Odds deals high damage to Terrorblade's illusions.

* Searing Arrows and Clinkz physical damage items is almost suicidal when used on Legion Commander, as it invites an instant Duel and Legion Commander herself is a natural Blade Mail carrier.
* Duel locks down Clinkz for a long duration, preventing him from escaping with Skeleton Walk.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Heroes who rely on summons will see them destroyed easily by Overwhelming Odds: Lycan, Arc Warden, Warlock, Chen

* Heroes with spell immunity-granting spells will render Phoenix useless against them, as Phoenix has almost no spell immunity-piercing ability, other than the stun at the end of Supernova: Lifestealer, Juggernaut.

* Rage prevents Earthshaker from damaging and stunning Lifestealer.
* Feast is very effective against Earthshaker, because of him being a strength hero, allowing Lifestealer to heavily harass and kill him.
* Open Wounds prevents Earthshaker from escaping after he initiated.
* Infest gives Lifestealer an easy way to escape should he get caught out by Earthshaker.

* Lifestealer's Rage negates Sand King's spells which do magical damage.

* Pudge, Legion Commander and Axe will make the match a living hell for you, since they are known for surprise attacks from the fog and quickly killing low HP heroes. They can also interrupt your channeling, Legion being especially problematic, as she can use Press the Attack on an ally who is hexed as well.

* Lifestealer excels at killing high health heroes with Feast, and Sven is no exception.
* Rage stops Storm Hammer from hitting Lifestealer.
* Rage and Open Wounds helps Lifestealer survive against Sven's high physical damage.

* Heroes with spell immunity or pseudo-blinks which provide invulnerability: Lifestealer, Juggernaut, Omniknight, Huskar , and Tusk have spells which allow them to easily escape Dream Coil.

* Overwhelming Odds deals high damage to Phantom Lancer's illusions.
* Duel's long duration prevents Phantom Lancer from using Doppelganger.