* Finger of Death's burst damage can kill him due to his low health pool, and Ethereal Blade only makes it worse. If Lion purchased an Aghanim's Scepter, the situation only grows worse.
* If Meepo ganks Lion with Poof and Earthbind, he will be an easy target for Earth Spike & AoE Hex from his level 25 talent.

* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.

* Despite her high mobility, Hex or Earth Spike can lock Phantom Assassin down and make her vulnerable.
* Although she has high evasion through Blur, Phantom Assassin has a rather low health pool, making her weak to Lion's magical burst.
Additional:
* Hex and Earth Spike's fast cast animations easily catches Phantom Assassin when she jumps in to attack.
* Finger of Death often ends Phantom Assassin before she can do anything in the early to mid game.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge.

* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin

* Heroes under Guardian Angel can be still damaged from the pure damage of Black Hole and Midnight Pulse.

* The area of effect damage from Midnight Pulse and Black Hole help deal with Chaos Knight's illusions.
Additional:
* Black Hole usually catches Chaos Knight with all his illusions.
* Midnight Pulse deals damage based on max health, quickly killing Phantasm illusions.

* One of Lion's level 20 talents lets Mana Drain affect 2 secondary targets. This can make things difficult for heroes like Phantom Lancer, Chaos Knight, and Terrorblade who rely on illusion armies.
* Mana Drain and Hex instantly kill any illusions. Finger of Death upgraded with Aghanim's Scepter also shreds most illusions.
* One of Lion's level 20 talents lets Mana Drain affect 2 secondary targets. This can make things difficult for heroes like Phantom Lancer, Chaos Knight, and Terrorblade who rely on illusion armies.

Additional:
* Mana Drain is a real problem to Chaos Knight early game, considering his already low mana pool.
* Aghanim's Scepter upgraded Finger of Death is an AoE ability, which can deal a tremendous amount of damage to his illusions.
* Hex with a level 25 talent instantly disposes Chaos Knight's illusions.

* Malefice prevents Spirit Breaker from using his spells for the duration.
* Demonic Conversion's eidolons have high magic resistance, receiving little damage from Charge of Darkness.

* Mana Drain has an extremely long range and low cooldown. It can easily deplete most heroes of their entire mana pools, especially those with smaller mana pools such as Tiny or Spirit Breaker.

* His ultimate will be a double edged sword for him if he ever dares to use it by risking max health based damage of Enigma.
* Enigma can mass ranged summons which he's rather helpless against.

* Heroes with high magical burst can easily kill Huskar when he is at low health: Lion, Lina, Skywrath Mage

* Lion's disables are also really effective against channeling Heroes, like Enigma or Crystal Maiden.

* She will be not able to cast her ultimate while under Malefice's debuff.
* Enigma's Black Hole can cancel Freezing Field's channeling regardless of her Glimmer Cape and Black King Bar.

* In general, heroes such as Lion, Silencer, Skywrath Mage, Sven, Ogre Magi and others with reliable disables are crucial to killing Techies before they can suicide.

* Heroes with summons like Broodmother,Enigma, Invoker, Nature's Prophet, Lycan, Visage;or illusions, like Naga Siren, Phantom Lancer, Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity mines in the early game.

* Heroes with high burst damage: Lina, Lion, Luna, Nyx Assassin, Queen of Pain.

* Heroes with channeling spells because Shadow Fiend has nothing to cancel channeling: Bane, Enigma, Pudge, Shadow Shaman.

* Viper cannot interrupt heroes with powerful channeling abilities: Bane, Enigma, Shadow Shaman, Warlock

* Heroes that can drain mana negatively affect Viper's ability to use Poison Attack, Nethertoxin and Viper Strike: Lion, Anti-Mage

* Lion possesses two strong disables in Earth Spike and Hex and heavy magic burst with Finger of Death which help lock him down and prevent him from escaping with Activate Fire Remnant. When getting his Blink Dagger Lion can punish Ember Spirit's overextension immediately, or initiate a fight on him with disables.
Additional:
* Ember lacks any protection against Lion's disables early in the game and often does not acquire any later, allowing Lion to Hex or Earth Spike him before he escapes through his Fire Remnant.
* Although Flame Guard can prevent magic damage, it does not stop Lion's disables, and Lion can usually break through it with Finger of Death.

* All of Lion's abilities are active making Demonic Purge break from Aghanim's Scepter useless.
* Hex and Mana Drain can make quick work of whatever illusions you're creating, especially when he acquires his Talents as level 20 and 25.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Earth Spike or Finger of Death with Aghanim's Scepter for the enemy.

* Malefice keeps Tree Dance on cooldown, and can interrupt Wukong's Command's long cast time.
* Midnight Pulse destroys a large amount of trees.
Additional:
* Malefice will cause Monkey King to struggle without Black King Bar, as its periodic damage and stun disables/interrupts abilities, such as Tree Dance and Wukong's Command.
* Midnight Pulse also destroys trees in a wide radius, stunning Monkey King if he happened to be on a tree caught within that AoE.

* Mana Drain rapidly saps Morphling's already low mana pool, making him unable to use Waveform or Adaptive Strike. Additionally, Hex prevents these abilities as well.
* An Earth Spike and Finger of Death combo can burst an unwary Morphling down if he has his strength fully shifted to agility.

* Lion will continuously Mana Drain Tiny, depleting his small mana pool for his abilities.
* Hex will keep Tiny from using his high damage spells and attack damage.

* Lion has two low cast point disables (Hex and Earth Spike) to control Ursa before he buys a Black King Bar.
* Hex is one of the few abilities that cannot be dispelled even with an Aghanim's Scepter upgraded Enrage.
* Lion can control Ursa's low mana pool via Mana Drain.

* With a lot of disables with good range, he might cancel your Echo Stomp.
* Mana Drain can be used to drain Elder Titan's already low mana pool.

* Both Hex and Mana Drain destroys Naga Siren's illusions in an instant, making it hard to teamfight or push against a team with Lion. If Lion chooses the AoE effect talent for Hex or the multi-target Mana Drain, it can negate her pushing potential entirely.
* Earth Spike is an AoE disable with good damage. If used well, it can help distinguish the true Naga Siren by the damage they take (illusions take more damage).

* Hex greatly reduces Timbersaw's mobility.
* In addition, Lion can follow up with his Earth Spike and Mana Drain combo, preventing Timbersaw to escape with Timber Chain. And he can finish Timbersaw off with Finger of Death if the latter's HP is low enough.

* Although Weaver can potentially Time Lapse out of any burst, Weaver has a fragile health pool, and Lion's disables can kill him before.
* Weaver is very mana dependent and has a rather small mana pool in the beginning of the game. Mana Drain can deplete him of mana and lessen his early game presence.
* Earth Spike can be point targeted and hits through Shukuchi to make him vulnerable.
* Linken's Sphere is easily broken by targeted spells with low cooldown.

* Can cast Demonic Conversion on one of Lycan's Wolves, making this a numbers fight.
* Malefice will greatly reduce his ability to engage
* Midnight Pulse can steep an area making it harder for Lycan to engage in.

* Enigma's Eidolons can help soak Juggernaut's Omnislash in the early game, mitigating the damage and wasting it on disposable summons. Should Juggernaut choose to kill your Eidelons with Blade Fury, he leaves himself open to your disables.
* Enigma's Black Hole and Midnight Pulse damage can pierce through Juggernaut's Blade Fury.

* One of the slowest heroes fall prey to an area nuke quickly when caught off-guard.

* Mana Drain depletes Nercophos' mana pool, preventing him from using his abilities.
* Finger of Death deals high magical damage, which becomes amplified by Ghost Shroud.

* Drow has a very low health pool, allowing Lion to burst her down.
* Drow has no innate escape mechanism, making her an easy target for Lion's disables.
* Lion should be wary of Drow's Gust however, as he has no natural means to deal with it.

* Mana Drain is very effective against heroes that have mana burn abilities such as Anti-Mage, Nyx Assassin and Keeper of the Light.

* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage

Additional:
* Enchantress is very fragile without any form of magic resistance, allowing Lion to easily burst her down.
* Nature's Attendants is a slow heal, making it ineffective against Lion's burst.
* Enchantress lacks any escape mechanism apart from her raw movement speed, allowing Lion to disable her.
* Since Lion's damage comes mostly from his skills, Untouchable does nothing to mitigate it.

* Heroes with high magical burst damage will kill Gyrocopter before he gets to do much: Lina, Lion, Zeus

* One of Lion's level 20 talents lets Mana Drain affect 2 secondary targets. This can make things difficult for heroes like Phantom Lancer, Chaos Knight, and Terrorblade who rely on illusion armies.
* Mana Drain and Hex instantly kill any illusions. Finger of Death upgraded with Aghanim's Scepter also shreds most illusions.
* One of Lion's level 20 talents lets Mana Drain affect 2 secondary targets. This can make things difficult for heroes like Phantom Lancer, Chaos Knight, and Terrorblade who rely on illusion armies.

* One of Lion's level 20 talents lets Mana Drain affect 2 secondary targets. This can make things difficult for heroes like Phantom Lancer, Chaos Knight, and Terrorblade who rely on illusion armies.
* Mana Drain and Hex instantly kill any illusions. Finger of Death upgraded with Aghanim's Scepter also shreds most illusions.
* One of Lion's level 20 talents lets Mana Drain affect 2 secondary targets. This can make things difficult for heroes like Phantom Lancer, Chaos Knight, and Terrorblade who rely on illusion armies.

* Heroes with high burst damage through their physical attacks or spells can kill Dazzle or his allies before he has a chance to use Shallow Grave. (Lina, Lion, etc.)

* High priority targets like Queen of Pain, Drow Ranger and even Anti-Mage can't get caught out from Lion's long range disables.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

* Ranged heroes that can easily harass Axe: Drow Ranger, Sniper, Lion.

* Finger of Death can instantly shred many targets especially fragile Heroes like Keeper of the Light, Ancient Apparition, or Bounty Hunter.

* Heroes that can kill Death Prophet with nukes can prevent her from using Exorcism to its full duration or using it at all: Lina, Lion, Puck, Morphling.

* Since Windranger is bad against magical damage, heroes with continuous magical damage or magical nukes can blast her: Zeus, Tinker, Leshrac, Viper, Skywrath Mage, Lion, Lina, Venomancer.

* Finger of Death can instantly shred many targets especially fragile Heroes like Keeper of the Light, Ancient Apparition, or Bounty Hunter.

* Heroes with the capability of removing or destroying trees greatly hinders the effectiveness of Treant Protector's abilities: Batrider, Nature's Prophet, Lina, Enigma, Mars

* Hex's instant cast time will force Brewmaster into the awkward situation of needing some form of spell immunity or block to prevent being immediately hex upon blinking in, or wait until Lion has used all his crowd control before entering a fight. His direct magic burst also makes Brewmaster's Drunken Brawler worthless versus Lion.

* Mana Drain is a headache for Bristleback to deal with during the laning stage, as it denies him the ability to get last hits with Quill Spray.
* Finger of Death deals high damage to Bristleback, and only triggers his passive once.

* Lacking any stun and being heavily dependent on his physical attacks and spell immunity, Lifestealer has no way to stop Black Hole, assuming he does not initiate Enigma first with Abyssal Blade.
* Enigma's abilities, with exception of Malefice, can pierce spell immunity and deal pure damage (and percentage-based damage in Midnight Pulse's case), putting Lifestealer in potentially adverse situations.

* Medusa lacks mobility or escape mechanisms. Earth Spike and Hex can neutralize her strong damage potential and allow for Lion's team to focus her down.
* In addition to easily breaking her commonly bought Linken's Sphere with its low cooldown, Mana Drain can quickly drain her Mana Shield, making her far less tanky.

* Heroes with other kind of disables that pierce spell immunity can hold Pangolier in place during Rolling Thunder: Axe, Beastmaster, Enigma, Magnus, Pudge, Batrider, Bane, Winter Wyvern

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King.

* Heroes with long or multiple disables will prevent Legion Commander from winning Duels: Shadow Shaman, Lion

* Heroes with long disables, like Lion, Night Stalker, or Legion Commander, can prevent Oracle from using spells or items.

* Wraith King has a very low mana pool and depends on it to cast Reincarnation. Mana Drain will render him useless.
* Wraith King has very low mobility, making it easy for Lion to disable and harass him.
Additional:
* While not being able to confront Wraith King by himself, Lion's Mana Drain helps in draining Wraith King's mana, preventing him from reincarnating.
* Lion's Earth Spike and Hex provide decent lockdown against Wraith King as well, preventing the latter from benefiting from Vampiric Aura bonuses.

* Hex and Mana Drain can be used to immediately destroy Spectre's illusion when she Haunts. A fast fingered Lion can protect himself and a teammate.
* Hex and Earth Spike are good lockdown spells to control and kill Spectre, especially if she doesn't buy defensive items like Linken's Sphere and Black King Bar.
* Finger of Death can be used to burst down Spectre when she is low on life as she has very poor magic resistance.

* Hex and Earth Spike can hold Clinkz down, giving him no chance to use Black King Bar or Skeleton Walk.
* Finger of Death quickly kills Clinkz, due to his low health.