* Doom alone can easily pick off Crystal Maiden since she is fairly fragile, even with using only basic attacks, Infernal Blade, and Scorched Earth.
* Doom prevents her from using any abilities in a fight, making her impact negligible.
* Devour allows Doom to acquire a stun, allowing him to cancel Freezing Field without having to use Doom.

* Sacred Arrow can be used to interrupt Freezing Field from a safe distance, forcing her to cancel it to dodge or get hit.
* Crystal Maiden has very slow movement speed, making her an easy Sacred Arrow target.
* Crystal Maiden has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
* If Frostbite has already been used, Mirana can Leap away even when slowed by Crystal Nova or Freezing Field.

* Doom disables the toggling of Rot and, if cast at the right time, may leave Pudge with a potentially lethal health drain.
* Doom's naturally high health, strength gain and damage output makes him a poor target for Pudge.
* The damage of Doom's Infernal Blade scales with the target's maximum health, which is particularly effective against Pudge due to his naturally high health and further health granted by stacks of Flesh Heap.
Additional:
* Infernal Blade deals high damage to Pudge due to his high strength grow with Flesh Heap.
* Using Doom with timing against Pudge who had just activated Rot would usually kill him.

* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.

Additional:
* If Meat Hook is used before Leap, Mirana may be able to escape Pudge's grasp by leaping to safety.
* The invisibility from Moonlight Shadow gives a degree of mobility, which can make Mirana or her teammates a difficult target to hook.
* Sacred Arrow can be used to cancel Dismember within a distance.

* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.

* Doom pierces spell immunity and can prevent Enigma from casting any spells or using items until the duration of the spell depletes, as well as damaging him over time. This can however, be blocked by a Linken's Sphere.
* An Enigma with a Helm of the Dominator can potentially feed his dominated creeps to Doom's Devour, giving Doom the abilities and benefits instead.

* Ethereal state disarms the target and makes them more vulnerable to magic damage, both of which Phantom Assassin despises. Especially Pugna and any hero that is wielding Ethereal Blade, such as Mirana, Nyx Assassin or Morphling.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Leap allows Mirana to easily escape Torrent and Ghostship.

* Doom has several disable abilities to choose from jungle creeps (e.g. War Stomp, Ensnare) to deal with Shadow Fiend who lacks escape abilities.
* When Doom combines creep abilities with Scorched Earth, Infernal Blade, and Doom, Shadow Fiend most likely will die as he cannot use Shadowraze and Requiem of Souls to protect himself, and also cannot even flee by using Shadow Blade or Blink Dagger.
* Although Shadow Fiend has a high physical damage output, Doom has a large health pool to survive it, meaning Doom's combo with high magical damage output will shutdown Shadow Fiend first.
* Doom usually buys Radiance to improve his damage, making his nuke combo more deadly to Shadow Fiend. The blind also prevents Shadow Fiend from landing his attacks often.

* Infernal Blade deals scaling damage and is useful against high health targets such as Bristleback.
* Doom disables Bristleback's low cooldown abilities, preventing him from triggering Warpath. With Aghanim's Scepter, it also breaks Bristleback's passive, rendering him more vulnerable.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Bristleback.
* If Doom gets an Aghanim's Scepter, he can disable Bristleback, taking away much of his durability.
* Doom prevents Bristleback from casting his two low cooldown abilities, which then prevents him from utilizing Warpath.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Axe more than most normal attacks, negating some of his tankiness. With Aghanim's Scepter, Counter Helix is also disabled, making him effectively useless for a lengthy duration.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Axe.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom's naturally low attack speed makes Counter Helix less likely to proc.
* Doom makes Axe less disruptive, preventing him from using his skills or items.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Axe.
* Doom has low attack speed because of his high Base-Attack-Time, poor agility gain and limited attack-speed granting items which are commonly built. This means Doom will trigger Counter Helix less often and thus is an unideal target for initiation.
* Doom has naturally high HP so it takes longer for Doom to be brought down to the killing threshold of Culling Blade.
* Axe is highly reliant on his abilities and items to be effective during a fight. Without the usage of Berserker's Call and Blink Dagger, Axe offers very little in the way of damage.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Spectre more than most normal attacks, negating some of her tankiness.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Spectre.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom makes Spectre less disruptive. Combined with Aghanim's Scepter, it will break Spectre passive skills, reducing her potential in teamfights.

* Techies spends lots of time standing still planting stacks of Land Mines away from creep waves.
* Sacred Arrow can be used to scout hidden Land Mines among trees and at uphill places. It can also be used to catch Techies while he's planting them.
* If Techies is hit with a Sacred Arrow, he can be killed before he has a chance to use Blast Off!.
* Mirana has a high attack range to destroy his traps from a safe distance.

* Doom shuts down Timbersaw completely, negating his mobility and preventing him from doing any damage.
* Infernal Blade can stun Timbersaw several times in a fight, potentially interrupting Timber Chain. It also breaks Reactive Armor's passive bonuses from Aghanim's Scepter.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Timbersaw.
* Timbersaw is extremely reliant on his abilities to be effective during a teamfight - both for mobility, damage and crowd control. Timbersaw offers very little impactful right-click damage, and thus Doom is particularly crippling against this hero.
* Additionally, when upgraded with Aghanim's Scepter, Infernal Blade breaks Reactive Armor, which effectively removes the durability which Timbersaw is commonly known for.

* Tinker is heavily reliant on casting his spells and Doom can disable all of his abilities and items. An Aghanim's Scepter only makes it harder for Tinker to survive.
Additional:
* Tinker is heavily dependent on active abilities and Doom prevents him from using any of them.

* Doom completely takes Invoker out of a team fight, a hero who relies on using abilities and items to contribute.
Additional:
* Doom is a good way to shut down Invoker, preventing from casting spells and using items for a lengthy time, thus forcing him to invest on Linken's Sphere.

* Doom makes Ogre Magi less disruptive.
* Infernal Blade effectively negates Ogre Magi's tankiness.
* With Aghanim's Scepter he can disable Multicast.

* Doom can stop Death Prophet from casting spells, which makes her useless during team fights if she didn't cast Exorcism before the fight. Furthermore, Doom can use Scorched Earth to chase after her.

* Doom is effective against every hero, and Void Spirit is no exception. Being unable to cast spells or items during fights for 16 seconds nullifies his impact entirely.
* Doom has a very versatile build and can consume creeps which has abilities that can stun or provide additional magic resistance.
* Doom's high strength gain and versatility in items can be effective against Void Spirit's magical damage.

* Doom makes Ursa less disruptive, and it cannot be dispelled with Enrage upgraded with Aghanim's Scepter.
* Aghanim's Scepter upgraded Infernal Blade can break Fury Swipes, negating much of his damage output.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Tidehunter.
* If Doom gets an Aghanim's Scepter, he can also disable Kraken Shell, reducing his survivability and tankiness.
* Doom prevents Tidehunter from casting his Gush, Anchor Smash and Ravage, making him useless in team fights.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Elder Titan.
* Doom has very low base armor and naturally high HP, so he isn't significantly affected by Natural Order.

* Scorched Earth can be used to engage Visage while removing Gravekeeper's Cloak charges.
* Infernal Blade will deal tremendous amounts of damage over time due to Visage's high health pool.
* Doom completely nullifies Gravekeeper's Cloak and prevents Visage from casting spells.

* Mirana can disturb your channeling even if you are under the effect of invisibility thanks to Sacred Arrow.
* Mirana armed with an Aghanim's Scepter is known to be able to quickly burst down heroes - especially supports. Together with Ethereal Blade the bullying can continue for the whole match.

* Scorched Earth deals damage to Clinkz during Skeleton Walk.
* Doom shuts down Clinkz entirely, as it prevents him from casting any of his spells and contributing a large amount of damage in teamfights.

* Leap allows Mirana to easily escape the freezing range of Cold Feet. Mirana also tends to build Manta Style which dispels Cold Feet.
* During Moonlight Shadow, the invisibility makes it hard to catch Mirana's team with Ice Blast.
* Ancient Apparition's lack of mobility/escape capabilities makes him an easy target for Mirana at any stage of the game.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper

* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of Chen or Enchantress.

* The general opinion that Doom can counter Ember Spirit with his Doom is a misconception, as Doom has a long cast animation, so an attentive Ember Spirit can easily dodge it if he has a Fire Remnant nearby. Doom is still an extremely effective early ganker however, as his Scorched Earth and Infernal Blade damage can quickly overwhelm Flame Guard's magic damage absorption, leaving Ember Spirit with no protection against them. Additional skills that Doom can get from Neutral creeps can also help bully Ember Spirit early. Shadow Blade or Blink Dagger on Doom can also help, providing a good way to apply Doom on Ember Spirit.

Additional:
* Ember Spirit cannot use his Activate Fire Remnant while Doomed to escape from Doom.

* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of Chen or Enchantress.

* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: Lifestealer, Doom, Mirana, Clinkz.

* A couple of long-range heroes with excellent laning like Mirana, Lina, Necrophos, Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.

* Heroes with abilities that break Berserker's Blood, lowering Huskar's attack speed and health regeneration: Doom, Shadow Demon, Viper.

* Silencer's Global Silence and Doom's Doom makes Earthshaker temporarily useless.

* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes has attack range talent can also outrange Plague Ward.

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

* Faceless Void relies on Time Walk for mobility and survivability but he can be prevented from utilizing it through Doom.
* Doom has a high cooldown duration for every ability except Infernal Blade, so he is not significantly affected by Time Dilation.

* Doom can eats Nature's Prophet's treants with Devour and gains lots of gold.
* Doom usually buys Radiance or using his Scorched Earth deals a lot of damage to Nature's Prophet if they stand close to his Treants, as well as killing all of his Treants and getting lots of gold.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Nature's Prophet:
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer, Satyr Tormenter and etc. are good examples.
* Doom and a ministun from Infernal Blade's prevents Nature's Prophet from escaping with Sprout and Teleportation.

* Sacred Arrow's long stun duration can prevent Morphling from casting his Waveform or Morph Replicate, making him unable to escape and easier to gank.
* Moonlight Shadow also allows Mirana's team to surprise Morphling while he tries to push towers.
* Mirana usually buys Linken's Sphere to protect herself from single-target abilities, making Morphling's Adaptive Strike and Ethereal Blade harder to use on her.
* However, Mirana also provides a chance to become a good Morph target, allowing Morph to use Leap to run away, if necessary.

* Sacred Arrow can be used to interrupt Death Ward from a safe distance, forcing him to cancel it to dodge or get hit.
* Paralyzing Cask is a slow-moving stun, and Mirana can Leap away from her allies to keep it from bouncing.
* Witch Doctor has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.

* Doom shuts down Anti-Mage's escape capabilities with Blink. The ability also deals pure damage, which ignores the protection from Counterspell.
* If Doom has Aghanim's Scepter, Infernal Blade can hit Anti-Mage loses his Mana Break and Counterspell, weakening both his offense and defense.
* Doom's low mana pool causes him to take little damage from Mana Void.
Additional:
* Doom prevents Anti-Mage from maneuvering around a fight or escaping from an initiation using Blink. Additionally, Doom deals pure damage, which is not affected by Counterspell. This can quickly whittle away Anti-Mage's naturally poor health pool.
* Be careful when using Doom as a well-timed Counterspell can block and reflect it back against Doom himself.
* An Aghanim's Scepter upgraded Infernal Blade will also disable Mana Break and Counterspell, which makes Anti-Mage significantly less effective in fights and more susceptible to the high magical damage of Doom's abilities and any allies'.

* Doom prevents Storm Spirit from using all of his abilities and items, rendering Storm Spirit useless in a fight.

* Doom turns Omniknight into a walking creep, or completely takes out his buffed cores, also removing Guardian Angel in the process.
* Doom has access to Satyr Banisher's Purge, which allows him to remove Guardian Angel.
Additional:
* Doom applies a basic dispel upon cast, so it can remove Guardian Angel.
* Casting Doom on Omniknight will prevent him from healing allies with Purification, or casting buffs like Heavenly Grace and Guardian Angel.

* A well-timed Doom prevents Nyx Assassin escaping with Vendetta and does not allow him to disengage with Spiked Carapace.
* Doom's high HP easily shrug off Nyx Assassin's burst damage and fend him off.

* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

Additional:
* Doom can completely shut down Dazzle through Doom, as it prevents him from casting his abilities and, by extension, gaining Bad Juju stacks.

* Mirana can destroy Tombstone, and evade zombies using Leap and Moonlight Shadow's invisibility.

* Lion lacks mobility or escape mechanisms, making him an easy target for abilities like Mirana's Sacred Arrow or Leshrac's Split Earth, or combos like Kunkka's X Marks the Spot into Torrent.

* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.

* An Aghanim's Scepter-upgraded Infernal Blade can be useful against heroes with troublesome passive skills: Phantom Assassin, Enchantress, Huskar, Underlord.

Additional:
* Infernal Blade does damage based on percentage health, and is useful against high health pool hero like Underlord
* Doom can prevent Underlord from spamming his abilities and most important is prevent him from using Dark Rift to escape

* Arc Warden relies on items and abilities, as well as his {U:Tempest Double}, to deal damage to enemies. Doom effectively denies that and makes Arc Warden useless in fights.