* Earthbind disables Waveform, effectively keeping Morphling in place for an extended period of time, allowing Meepo to deal considerable damage with Poof.

* Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by Poof and Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.

* Heroes with silencing abilities that are not blocked by Linken's Sphere, like Puck's Waning Rift, Death Prophet's Silence or Silencer's Global Silence.

* Puck can initiate on Mirana with Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can dodge Sacred Arrow and Starstorm with Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving Sacred Arrow, and also can avoid Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot Leap away.

* Arcane Orb deals pure damage, effectively bypassing Morphling's high armor from Attribute Shift (Agility Gain).
* Sanity's Eclipse is more effective against a low health and mana pool Morphling, enabling Outworld Destroyer to burst Morphling down before he can shift to Strength.
Additional:
* Arcane Orb deals high damage regardless of Morphling's high armor from Attribute Shift (Agility Gain).
* Because of Morphling's very low intelligence gain and base intelligence, Sanity's Eclipse will almost always be effective against Morphling.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Counterspell's bonus magic resistance causes the Ethereal Blade and Adaptive Strike combo to deal significantly less damage.
* Counterspell's active component can reflect the Ethereal Blast and Adaptive Strike combo back into Morphling, dealing significant damage or even killing him.
* Mana Break combined with Manta Style can quickly burn away Morphling's mana, leaving him unable to use his spells.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* If Slark sees the Sacred Arrow before it hits him, he can use Dark Pact to remove it a moment later.
* Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's Aghanim's Scepter​ combo with Shadow Dance.

* Eul's Scepter of Divinity and Light Strike Array combo will disable Mirana if she tries to Leap away.
* Laguna Blade's magical (pure with Aghanim's Scepter) burst damage takes advantage of Mirana's below average health.
Additional:
* Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with Moonlight Shadow.

* Heroes with high damage output who can burst down Morphling before he has time to use Attribute Shift (Strength Gain), like Lina and Lion.

Additional:
* Light Strike Array catches Morphling while he jumps in from Waveform and also prevents Morphling from using his abilities.
* Laguna Blade can kill Morphling quickly before he shifts into Attribute Shift (Strength Gain).

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Time Dilation affects Morphling's low cooldown spells, making them unusable for a long time, rendering Morphling nearly useless.
* Morphling cannot use Attribute Shift while he is inside Chronosphere which makes it easy to kill him.

* Arc Warden can counter Morphling's strong pushing capabilities by using Magnetic Field to protect buildings.
* Arc Warden also often builds an Orchid Malevolence or Bloodthorn, which can prove dangerous for Morphling.
* Arc Warden can easily break Linken's Sphere with Flux and then slow him with Spark Wraith, making Arc Warden's Tempest Double a legitimate threat as well.

* Flux will slow and damage Mirana even after she Leaps, since she will likely not be near allies.
* Arc Warden can place Magnetic Field on an ally who has been hit by Sacred Arrow to protect them.
* As Necronomicon is his core item, Arc Warden can reveal Mirana and her allies hiding in Moonlight Shadow and the Necronomicon Warrior can kill Mirana with Last Will if he is unintentionally killed with Starstorm upgraded by Aghanim's Scepter or Sacred Arrow.
Additional:
* If Arc Warden builds Necronomicon 3 he can reveal Mirana's team while Moonlight Shadow is active.
* A Starstorm upgraded by Aghanim's Scepter can accidentally kill a Necronomicon Warrior, which can lead to her death if she hasn't built a Black King Bar.
* Arc Warden can use his summons to prevent Sacred Arrow from hitting himself or his allies.
* Mirana doesn't build items that give armor often, so she usually can't fight against a late game Arc Warden.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Heroes with silencing abilities that are not blocked by Linken's Sphere, like Puck's Waning Rift, Death Prophet's Silence or Silencer's Global Silence.

* Mirana's Leap is ineffective if Lycan uses Shapeshift. It also allows him to dodge Sacred Arrow.
* As a natural Necronomicon carrier, he can reveal Mirana and her allies hiding in Moonlight Shadow and the Necronomicon Warrior can kill Mirana from an unintentional Sacred Arrow or Starstorm upgraded with Aghanim's Scepter.

* The long silence of Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With Dark Ascension and Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.

* Abaddon can remove Sacred Arrow's stun from his teammates with Aphotic Shield, or remove it from himself with Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's Aghanim's Scepter combo.
Additional:
* Sacred Arrow can be instantly dispelled by Aphotic Shield.

* Sharpshooter can kill easy when Morphling is going on full agility strategy (Only in early and mid game).
* Scurry can help to catch up Morphling when using Waveform or for escape.

* Mana Drain rapidly saps Morphling's already low mana pool, making him unable to use Waveform or Adaptive Strike. Additionally, Hex prevents these abilities as well.
* An Earth Spike and Finger of Death combo can burst an unwary Morphling down if he has his strength fully shifted to agility.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Arcane Bolt's low cooldown allows him to deal consistent damage to Morphling, and is a viable way to disable Linken's Sphere.
* Ancient Seal prevents Morphling from using any of his skills, giving Skywrath Mage and his team ample time to burst Morphling down.
* Mystic Flare coupled with a stun/root can easily burst Morphling down, especially if he has more stats shifted to Agility.
* Alternatively, Morphling can use Morph to use Skywrath Mage's own silence and nukes against him.

* Void Spirit can greatly pressure Morphling's farm, which is very bad for a hero who needs a large amount of space.
* Waveform does not provide better mobility than Astral Step.
* If Morphling shifted all of his strength to agility, he can be bursted down by Void Spirit before he can react.
* Doing an Ethereal Blade combo on Void Spirit is incredibly difficult, as Dissimilate and Astral Step can allow him to escape or dodge the projectile.

* Most of Morphling's armor comes from his high agility and it is reduced by Natural Order.
* However, the aura has only 350 range and Elder Titan can be bursted down by Morphling's nuke combo if he isn't careful.
Additional:
* Morphling's high armor is primarily from Morphing agility, which is reduced by Natural Order therefore making the hero very vulnerable when it has morphed a lot into agility.
* Morphling usually will Morph into high agility and low strength. This can be taken advantage of with a good stun or silence or by bursting him down before he has the time to Morph back to strength.
* Morphling is very vulnerable to Blade Mail under Natural Order and can easily burst himself down with his own auto-attacks or his magical damage combo.

* Geomagnetic Grip is not blocked by Linken's Sphere and can silence Morphling, preventing Morphling from using Waveform or Attribute Shift to escape from ganks.
* In addition, Boulder Smash and Rolling Boulder provide a solid lockdown if used together.

* Jumping on Axe from Waveform he will be an easy target for a counter-initiation with Berserker's Call.
* Morphling is often played at low health to maximize the bonuses from Attribute Shift (Agility Gain), and also because his abilities cost health to use. This makes him especially vulnerable to Culling Blade.
* However, Morphling is common Linken's Sphere carrier to block Culling Blade forces Axe to use Battle Hunger to pop the Spell Block first.
* Attribute Shift (Agility Gain) gives Morphlig no protection against the pure damage of Culling Blade. Its attack speed bonus also means that Counter Helix will proc more often.

* Rubick's ability to steal Attribute Shift (Strength Gain) makes him extremely annoying to deal with because Rubick's shifted attributes will remain even if he steals a new spell.
* If Rubick moves enough points to strength and then steals Adaptive Strike, he will have a powerful 3-second ranged stun in his arsenal as well.
* Waveform provides a reliable nuke/escape to Rubick.
* Rubick can steal most abilities Morphling uses while Morphed, allowing Rubick to steal his own allies' abilities if the Morphling is not careful.
Additional:
* Morphling's abilities can cause unique interactions on their own:
* Waveform is a damaging pseudo-blink, giving Rubick much needed mobility.
* Attribute Shift (Strength Gain) is a great ability for Rubick:
* The changes done by it are permanent even after losing the ability. Pumping all the agility into strength makes him much tankier. The armor loss due to reduced agility can be mitigated by cheap items like Medallion of Courage or Solar Crest.
* The extra strength allows Rubick to survive Morphling's Ethereal Blade - Adaptive Strike (Agility) combo.
* Beware when using Attribute Shift (Agility Gain)! Unlike Morphling, Rubick does not gain damage from it, since agility is not his primary attribute.
* Adaptive Strike (Strength) is a long-ranged stun.
* The true power of this ability is revealed when Attribute Shift (Strength Gain) has been stolen previously: it gives a 4 second ranged stun every 10 seconds, which greatly counters heroes with mobility, such as Morphling himself.
* All of Rubick's abilities break Linken's Sphere, a core item for Morphling.

* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Heroes that rely on right-clicks will find that their attacks will miss a lot, due to Whirling Axes (Melee)'s miss chance. Such heroes include Phantom Assassin, Terrorblade, and Morphling.

* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.

* Underlord's Atrophy Aura reduces Morphling's high base damage gained through agility shift.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Jakiro's early pushing ability from Liquid Fire makes Jakiro very strong against heroes, that take a long time to get online: Morphling, Naga Siren, Spectre.

* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.

* Necrophos's Reaper's Scythe can finish off a low-health Morphling.

* Overgrowth has a great duration, which prevents the units caught from attacking, moving and Blinking. Heroes like Storm Spirit, Mirana, Anti-Mage and others won't be able to do much if they're caught.

* Winter Wyvern's Winter's Curse turns Morphling's high attack damage and attack speed against his targeted teammate.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.

* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.