* Heartstopper Aura can do a decent damage overtime to Chen's High-Health-Creep Army, and Chen does not have any source of burst damage to Necrophos.
* Necrophos can purchase a Spirit Vessel to provide an AOE debuff that reduce the healing from Divine Favor and Hand of God.

* Sticky Napalm slows Chen and amplifies Batrider's damage.
* Flamebreak and Firefly can deal heavy damage to Chen and his creeps.
* Flaming Lasso pulls Chen away from his creeps, often to certain death.
Additional:
* Sticky Napalm slows Chen and his creeps and Flamebreak and Firefly can deal heavy damage to them.
* Flaming Lasso pulls Chen away from his creeps, often to certain death.

* Necrophos' largely magical damage completely ignores Bulwark.
* Ghost Shroud protects Necrophos from God's Rebuke but more importantly stops Mars from being a threat in lane.

* Sticky Napalm slows turn rate, making it difficult for Mars to control the direction he is facing to activate Bulwark.
* Flaming Lasso disables Mars while enemies re-position themselves behind Mars to avoid Bulwark.

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

* Firefly allows Batrider to gain vision of Monkey King while he is on an tree, as well as destroying any nearby trees, denying Monkey King spots to jump to, or causing him to fall.
* Sticky Napalm's turn rate slow makes it significantly more difficult for Monkey King to jump from tree to tree and gain Jingu Mastery stacks. It also reveals Monkey King while he is on a tree.
* Flamebreak and Flaming Lasso enable Batrider to remove Monkey King out of Wukong's Command.
Additional:
* Firefly destroys trees and can turn Tree Dance into a free four second stun.

* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Frequent healing from Death Pulse and Mekansm makes it difficult for Axe to finish off targets with Culling Blade.
* Ghost Shroud's instant cast time allows Necrophos to turn ethereal before being initiated on by Berserker's Call. This prevents him from attacking Axe while taunted, thus lowering the chance to proc Counter Helix.
* Axe's high health is relatively ineffective against Heartstopper Aura's percentage-based health degeneration.
* Reaper's Scythe negates Axe's tankiness, and can kill him quickly after initiation.
Additional:
* Frequent healing from Death Pulse makes it difficult for Axe to finish off targets with Culling Blade.
* Reaper's Scythe negates Axe's tankiness, and can kill him quickly after initiation.
* Heartstopper Aura is effective due to Axe's high strength gain.

* Heroes that have high health but little to no magic resistance are easy prey for Necrophos, as no matter how high they build their health up, Reaper's Scythe will kill them outright as long as they fall under a certain threshold, and Heartstopper Aura will deal the same amount of damage regardless, decaying their health the longer they stay within range. As such, Strength heroes like Chaos Knight, Centaur Warrunner or Magnus are good targets for his ultimate.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King.

* Some heroes, such as Necrophos can be an issue if not initiated onto by Sven first.

Additional:
* His Heartstopper Aura deals the same gradual damage over time no matter how high Sven builds his strength or health pool up, and should he fall down to a certain percentage, his high health will no longer matter if Necrophos manages to land his Reaper's Scythe, killing him instantly. But it is best if Necrophos can either catch him off guard before he can possibly use his Black King Bar (which is an item Sven players commonly purchase), or bait him out of it.
* Ghost Shroud prevents Sven from hitting Necrophos, and if he doesn't have his Storm Hammer available, it could make him completely immune to Sven and allow Necrophos to easily kite him around.

* Batrider often hides in the trees to initiate on a target. As such, he has a slight edge against heroes that have no scouting tools and cannot see him coming, such as Lion or Sven.

* Heroes with disables that go through spell immunity can end Bloodseeker before he has the chance to do anything: Batrider, Beastmaster

* Heroes with area heals prevents Bloodseeker from bringing enemies low, and therefore deny him his Thirst bonuses and health return: Necrophos, Dazzle

* Firefly can be used to clear Nature's Prophet's treants and allowing to jump on Sprout.
* Flaming Lasso prevents Nature's Prophet escaping from Teleportation.

* Batrider's turn rate slow from Sticky Napalm makes it harder for Bristleback to keep his back towards the enemy.

* Reaper's Scythe and Heartstopper Aura deal percentage-based damage, ignoring Bristleback's high health.
* Heartstopper Aura's HP removal does not trigger Bristleback's passive.
Additional:
* Heartstopper Aura deals percentage-based damage flagged as HP removal, so it is not reduced by Bristleback, nor does it trigger passive Quill Sprays.
* Reaper's Scythe is very effective against Bristleback not only due to its percentage-based damage, but rather because it first stuns and then deals its damage, allowing Necrophos to position in front of Bristleback in time.

* Reaper's Scythe can kill Terrorblade quickly before he has chance to use Sunder.
* Ghost Shroud protects Necrophos against Terrorblade's high attack damage.

* Reaper's Scythe will turn Tiny's high health against him.
* Heartstopper Aura does substantial damage to Tiny as a result of his high max health.

* Heartstopper Aura is effective against high health heroes, and Pudge is no exception. Coupled with his constant self-damage from Rot, being around Necrophos could prove risky for an overconfident Pudge.
* Regardless of how much health Pudge gains through Flesh Heap, Reaper's Scythe will often kill Pudge should his health fall below a certain threshold, making Necrophos an ideal counter versus Pudge.
Additional:
* No matter how high Pudge builds up strength with his Flesh Heap, all it needs is for him to fall below a certain percentage of health for him to fall to Reaper's Scythe. Considering his constant self-damage with Rot, being around Heartstopper Aura will prove risky for an overconfident Pudge.

* As long as Batrider is under the effects of Firefly, he can safely fly over mines.
* Sticky Napalm also punishes low mobility heroes that like to kite, such as Techies, by lowering their turn rate dramatically. This can also potentially delay Techies' Blast Off! if Techies tries to cast Blast Off! in a direction he's not currently facing.
Additional:
* As long as Batrider is under the effect of Firefly, he can safely fly over Proximity Miness (He does not receive vision over the mines).

* With high health and rarely buying Linken's Sphere or Black King Bar, Centaur Warrunner is a good target for Reaper's Scythe. However, Centaur Warrunner can resolve this problem by buying Pipe of Insight or Hood of Defiance to diminish its damage.
* Heartstopper Aura will do well against high health heroes such as Centaur Warrunner.

* Due to Doom's naturally high health, strength gain and common itemization for durability, Heartstopper Aura is particularly effective. The health loss is also large enough that, throughout all stages of the game, the aura effectively neuters the health regeneration granted by Devour.
* Necrophos can help to keep both himself and his allies alive during Doom through his natural regeneration granted by Heartstopper Aura (which is not disabled by Doom), or in the case of an ally, through his Death Pulse. Additionally, Necrophos is an ideal Mekansm carrier. Should one be bought, kills against Necrophos' team can be difficult to secure due to the damage-over-time nature of Doom and his abilities.
* Doom typically wants to be a hero that soaks attention from the enemy team and takes the role of an initiator and disabler. As such, Doom is an ideal target for Reaper's Scythe, as it is likely Doom will be at the fore-front of any fight.

* Batrider's abilities are designed to deal damage over time, burning through Templar Assassin's layers extremely quickly. Flamebreak applies 7 instances of damage, burning through the entirety of Refraction, and Firefly applies damage on the place, forcing her to either get out of Meld and be attacked or stay in place or be incinerated.
Additional:
* Batrider's DoT damage quickly removes Templar Assassin's Refraction and can damage her during Meld.

* Frequent healing from Death Pulse and Mekansm/Guardian Greaves or Pipe of Insight makes it difficult for Earthshaker to execute his combo with Echo Slam.
* Necrophos usually buys Radiance to improve their burning aura damage from Heartstopper Aura will usually disable Earthshaker's Blink Dagger prior to a teamfight, preventing him from initiating or re-initiating.
* Reaper's Scythe allows to kill  Earthshaker while he blinks in, preventing him from executing his combo (although Earthshaker is rarely a primary target).

* Heartstopper Aura effectively negates Timbersaw's large HP pool as well as HP regen.
* Death Pulse together with health and mana regeneration from killed creeps helps Necrophos and his teammates survive Timbersaw's burst damage.
* As a tanky hero that stays in the middle of teamfights, Timbersaw is an easy target for Reaper's Scythe.

* Necrophos becomes a bigger threat the lower one's health gets, and unfortunately for Phoenix, most of its spells have noticeable health costs. Those costs, coupled with his Heartstopper Aura, means that staying in a teamfight for too long under Necrophos' presence will make Phoenix a more valid target for his ultimate, with its stun completely preventing any form of retaliation or protection. Necrophos players are also likely to buy more durability items such as Hood of Defiance, making him more able to withstand Phoenix's damage despite having no escape mechanisms.
* However, it is also important to remember that a Scepter-upgraded Supernova can help protect an ally from his ultimate.
Additional:
* Phoenix constantly depletes its own health due to the health costs of its abilities. Unlike heroes that have a similar mechanic, Phoenix does not benefit from low health, nor does it really have a countermeasure for it. As such, Phoenix is a very vulnerable target for Necrophos to prey on, especially when caught off guard before it can cast Supernova.

* Necrophos usually doesn't build much attack damage to steal from.
* He can use Ghost Shroud to prevent Razor from attacking him with the stolen damage from Static Link.
* Razor is somewhat vulnerable to magical damage, and Reaper's Scythe prevents him from escaping with his high movement speed when things get dangerous.

* Ghost Shroud can be use both offensively to slow Lone Druid or Defensively to prevent Lone Druid and The Spirit Bear from attacking him.
* Heartstopper aura burns the Spirit bear High HP over time. Additionally, it can deal decent damage to Lone Druid during his True Form.

* Because Huskar tends to stay at low health to gain the maximum bonuses from Berserker's Blood, it makes him an exceptionally prime target for Reaper's Scythe.
Additional:
* Huskar is often at low health, making him easy prey for Reaper's Scythe.
* Ghost Shroud prevents Huskar from stacking Burning Spear, and if Heartstopper Aura stacks are active, can regenerate health lost to existing stacks.

* Reaper's Scythe can kill Alchemist before Chemical Rage has the time to heal him.
* Ghost Shroud can prevent Alchemist from attacking Necrophos, as well as make him immune to Acid Spray and Unstable Concoction damage.
* Heartstopper Aura will do damage as long as Necrophos is alive based on health percentage, which is a problem for a strength hero such as Alchemist.

* Necrophos is a dangerous opponent to go against with. Regardless of how many strength Undying has gained from Decay, Necrophos can finish off Undying with Reaper's Scythe once Undying's HP falls below a certain threshold.
* Heartstopper Aura will do more damage to Undying if he gained strength from Decay, as it does damage based on a hero's maximum health.

* Death Pulse can easily wipe out Broodmother's spiderlings if they're too close while also offering Necrophos a source of regeneration for Broodmother's harass in lane.
* Ghost Shroud prevents Broodmother or her spiderlings from damaging Necrophos temporarily.
* Heartstopper Aura will regenerate lost health and mana for every spiderling or spiderite Necrophos manages to kill.

* Reaper's Scythe and Heartstopper Aura deal percentage-based damage, ignoring Underlord's high health.

* Heroes with catch to disrupt Sniper's positioning and deliver him into the enemies: Batrider, Disruptor, Pudge, Vengeful Spirit

* Necrophos's Reaper's Scythe can finish off a low-health Morphling.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Heroes that have escape abilities (such as Queen of Pain, Storm Spirit or Timbersaw) can be either nullified by Reaper's Scythe or a complimentary item for Necrophos (like Rod of Atos or Scythe of Vyse). If Necrophos is quick enough and enters range, they can quickly, if not instantly, die if they are not quick enough.

* Heroes with magical burst damage can often kill Phantom Assassin before she gets to do much: Necrophos, Nyx Assassin, Gyrocopter.

* Heroes with other kind of disables that pierce spell immunity can hold Pangolier in place during Rolling Thunder: Axe, Beastmaster, Enigma, Magnus, Pudge, Batrider, Bane, Winter Wyvern

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Heroes that have escape abilities (such as Queen of Pain, Storm Spirit or Timbersaw) can be either nullified by Reaper's Scythe or a complimentary item for Necrophos (like Rod of Atos or Scythe of Vyse). If Necrophos is quick enough and enters range, they can quickly, if not instantly, die if they are not quick enough.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Heroes with the capability of removing or destroying trees greatly hinders the effectiveness of Treant Protector's abilities: Batrider, Nature's Prophet, Lina, Enigma, Mars

Additional:
* Firefly will cut trees with ease, cleaning-up an area that's been enchanted with Eyes In The Forest, and potentially revealing a Treant under the effects of Nature's Guise.
* Batrider's DoT spells are also good versus Living Armor,

* Heroes with stronger lane presence that can threaten to kill him: Batrider, Juggernaut, Ursa, Monkey King, Razor.

* Heartstopper Aura and Reaper's Scythe go right through Dragon Knight's armor.

* Many stacks of Sticky Napalm, combined with Flamebreak and Firefly, allows Batrider to destroy illusions from Mirror Image.
* If Batrider can manage to destroy all illusions from Naga Siren, he will be able to use Flaming Lasso on the real one, and will be able to drag her toward his team, potentially preventing Naga Siren to escape with Song of the Siren.
Additional:
* Many stacks of Sticky Napalm, combined with Flamebreak and Firefly, allows Batrider to destroy illusions from Mirror Image.
* If Batrider can manage to destroy all illusions from Naga Siren, he will be able to use Flaming Lasso on real one, and will be able to drag her toward his team, potentially preventing Naga Siren to escape with Song of the Siren.

* Death Pulse can single out Spectre from her illusions, as well as heal his team against her. He also usually stands close to his allies for Death Pulse, effectively disabling Desolate.

* Heroes that can gain vision over trees to catch Tinker: Invoker, Shadow Demon, Batrider

* Heroes that have high health but little to no magic resistance are easy prey for Necrophos, as no matter how high they build their health up, Reaper's Scythe will kill them outright as long as they fall under a certain threshold, and Heartstopper Aura will deal the same amount of damage regardless, decaying their health the longer they stay within range. As such, Strength heroes like Chaos Knight, Centaur Warrunner or Magnus are good targets for his ultimate.

* No matter how Tidehunter builds tanky items such as (Guardian Greaves, Crimson Guard or Pipe of Insight), all it needs is for him to fall below a certain percentage of health for him to fall to Reaper's Scythe.