* With high health and rarely buying Linken's Sphere or Black King Bar, Centaur Warrunner is a good target for Reaper's Scythe. However, Centaur Warrunner can resolve this problem by buying Pipe of Insight or Hood of Defiance to diminish its damage.
* Heartstopper Aura will do well against high health heroes such as Centaur Warrunner.

* Kinetic Field and Glimpse can completely negate Stampede.

* Thunder Strike can be used to cancel Earthshaker's Blink Dagger.
* Glimpse brings Earthshaker back after he jumps on Aghanim's Scepter upgraded Enchant Totem.
* Static Storm if used on a fight can prevent Earthshaker from executing his combo after blinking in.

* Frequent healing from Death Pulse and Mekansm/Guardian Greaves or Pipe of Insight makes it difficult for Earthshaker to execute his combo with Echo Slam.
* Necrophos usually buys Radiance to improve their burning aura damage from Heartstopper Aura will usually disable Earthshaker's Blink Dagger prior to a teamfight, preventing him from initiating or re-initiating.
* Reaper's Scythe allows to kill  Earthshaker while he blinks in, preventing him from executing his combo (although Earthshaker is rarely a primary target).

* No matter how Tidehunter builds tanky items such as (Guardian Greaves, Crimson Guard or Pipe of Insight), all it needs is for him to fall below a certain percentage of health for him to fall to Reaper's Scythe.

* In the mid-game, Tidehunter relies on Kraken Shell to stay alive and get his Ravage off. Apart from Thunder Strike, none of Disruptor's abilities can be dispelled, so it's rather easy to trap him inside Kinetic Field and Static Storm.
* Be mindful, however, that Kraken Shell still makes Tidehunter very tanky, so be sure that you can kill him with your combo or your partners while he is silenced and trapped.

* Glimpse will return Underlord or any of his teammates attempting to escape with Dark Rift if timed correctly.
* Underlord is a slow and low mobility hero, easy to set up Static Storm and Kinetic Field, preventing him from using his abilities as well as preventing him using Dark Rift to escape

* Reaper's Scythe and Heartstopper Aura deal percentage-based damage, ignoring Underlord's high health.

* Heroes that have high health but little to no magic resistance are easy prey for Necrophos, as no matter how high they build their health up, Reaper's Scythe will kill them outright as long as they fall under a certain threshold, and Heartstopper Aura will deal the same amount of damage regardless, decaying their health the longer they stay within range. As such, Strength heroes like Chaos Knight, Centaur Warrunner or Magnus are good targets for his ultimate.

* Disruptor can disable Magnus's Blink Dagger using Thunder Strike during a considerable duration, disrupting his initiation attempts.
* Glimpse brings Magnus back after he escapes with Skewer and/or Force Staff.
* Static Storm if used on a fight can prevent Magnus from using Reverse Polarity after he jumps in.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Glimpse and Kinetic Field allows Disruptor to set up some early kills onto Shadow Fiend.
* Static Storm can be used to cancel the cast of Requiem of Souls.

* Blink and positioning is crucial for Queen of Pain. These factors are heavily countered by a good Glimpse.
* Static Storm is devastating for Queen as she relies heavily on her spells to inflict heavy burst damage.
Additional:
* Thunder Strike gives vision of Queen of Pain when she's trying to escape. When combined with Glimpse, her mobility and hit-and-run style can be negated.
* While in a team fight, Static Storm forces Queen of Pain to only use right-clicks.
* When combined with the Kinetic Field, she can only wait until she respawns.

* Heroes that have escape abilities (such as Queen of Pain, Storm Spirit or Timbersaw) can be either nullified by Reaper's Scythe or a complimentary item for Necrophos (like Rod of Atos or Scythe of Vyse). If Necrophos is quick enough and enters range, they can quickly, if not instantly, die if they are not quick enough.

* At around the 10-minute mark, Disruptor would normally be level 6 or 7. This means you can have a level 3/4 glimpse along with Static Storm. A high level glimpse is enough to pull Storm back to a Static Storm even after he used Ball Lightning due to his limited mana pool at that time.
* Be careful in the late game however, as there is a good chance he will kill you straight-out before Glimpse has finished bringing him back. Therefore Glimpse would simply bring him back to safety after he's murdered you or a teammate. Of course, this is assuming he hasn't silenced you with an item.

* Heroes that have escape abilities (such as Queen of Pain, Storm Spirit or Timbersaw) can be either nullified by Reaper's Scythe or a complimentary item for Necrophos (like Rod of Atos or Scythe of Vyse). If Necrophos is quick enough and enters range, they can quickly, if not instantly, die if they are not quick enough.

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

* Thunder Strike provides vision of Monkey King when he's in the trees. The periodic damage will also keep Monkey King from using Tree Dance if he's on the ground.
* Glimpse pulls Monkey King out of the trees if he attempts to escape using Tree Dance, and can cause Wukong's Command to end prematurely if Monkey King is Glimpsed out of its radius.
* Kinetic Field and Static Storm can be used to hold Monkey King in place and ensure a kill.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Heroes with magical burst damage can often kill Phantom Assassin before she gets to do much: Necrophos, Nyx Assassin, Gyrocopter.

* Due to Doom's naturally high health, strength gain and common itemization for durability, Heartstopper Aura is particularly effective. The health loss is also large enough that, throughout all stages of the game, the aura effectively neuters the health regeneration granted by Devour.
* Necrophos can help to keep both himself and his allies alive during Doom through his natural regeneration granted by Heartstopper Aura (which is not disabled by Doom), or in the case of an ally, through his Death Pulse. Additionally, Necrophos is an ideal Mekansm carrier. Should one be bought, kills against Necrophos' team can be difficult to secure due to the damage-over-time nature of Doom and his abilities.
* Doom typically wants to be a hero that soaks attention from the enemy team and takes the role of an initiator and disabler. As such, Doom is an ideal target for Reaper's Scythe, as it is likely Doom will be at the fore-front of any fight.

* Reaper's Scythe will turn Tiny's high health against him.
* Heartstopper Aura does substantial damage to Tiny as a result of his high max health.

* Ghost Shroud can be use both offensively to slow Lone Druid or Defensively to prevent Lone Druid and The Spirit Bear from attacking him.
* Heartstopper aura burns the Spirit bear High HP over time. Additionally, it can deal decent damage to Lone Druid during his True Form.

* Reaper's Scythe can kill Terrorblade quickly before he has chance to use Sunder.
* Ghost Shroud protects Necrophos against Terrorblade's high attack damage.

* Heartstopper Aura is effective against high health heroes, and Pudge is no exception. Coupled with his constant self-damage from Rot, being around Necrophos could prove risky for an overconfident Pudge.
* Regardless of how much health Pudge gains through Flesh Heap, Reaper's Scythe will often kill Pudge should his health fall below 40%, making Necrophos an ideal counter versus Pudge.
Additional:
* No matter how high Pudge builds up strength with his Flesh Heap, all it needs is for him to fall below a certain percentage of health for him to fall to Reaper's Scythe. Considering his constant self-damage with Rot, being around Heartstopper Aura will prove risky for an overconfident Pudge.

* Death Pulse can single out Spectre from her illusions, as well as heal his team against her. He also usually stands close to his allies for Death Pulse, effectively disabling Desolate.

* Disruptor can control where she goes with Kinetic Field and Glimpse. Static Storm shuts her down in teamfights.

* Frequent healing from Death Pulse and Mekansm makes it difficult for Axe to finish off targets with Culling Blade.
* Ghost Shroud's instant cast time allows Necrophos to turn ethereal before being initiated on by Berserker's Call. This prevents him from attacking Axe while taunted, thus lowering the chance to proc Counter Helix.
* Axe's high health is relatively ineffective against Heartstopper Aura's percentage-based health degeneration.
* Reaper's Scythe negates Axe's durability, and can kill him quickly after initiation.
Additional:
* Frequent healing from Death Pulse makes it difficult for Axe to finish off targets with Culling Blade.
* Reaper's Scythe negates Axe's tankiness, and can kill him quickly after initiation.
* Heartstopper Aura is effective due to Axe's high strength gain.

* Necrophos' largely magical damage completely ignores Bulwark.
* Ghost Shroud protects Necrophos from God's Rebuke but more importantly stops Mars from being a threat in lane.

* Thunder Strike provides vision on him while Slark is invisible.
* Glimpse's range at lvl 3-4 is more than enough to pull him back to a favorable position for your team to group up and kill him.
* Even though he is capable of picking you off and deal enough damage to kill you, Slark will be literally sticking his neck out, since jumping on Disruptor means being on his battleground.
* AoE silence and the ability to mute Black King Bar is deadly to Slark at all stages of the game.
Additional:
* Static Storm and Kinetic Field locks down Slark, as he cannot use Dark Pact to dispel any disables, or Pounce out while silenced.
* Glimpse puts an end to any attempts at ganking Disruptor or his allies, and also negates Slark's mobility by bringing him back into the fight if he tries to escape with Pounce.

* Heartstopper Aura effectively negates Timbersaw's large HP pool as well as HP regen.
* Death Pulse together with health and mana regeneration from killed creeps helps Necrophos and his teammates survive Timbersaw's burst damage.
* As a tanky hero that stays in the middle of teamfights, Timbersaw is an easy target for Reaper's Scythe.

* Necrophos is a dangerous opponent to go against with. Regardless of how many strength Undying has gained from Decay, Necrophos can finish off Undying with Reaper's Scythe once Undying's HP falls below a certain threshold.
* Heartstopper Aura will do more damage to Undying if he gained strength from Decay, as it does damage based on a hero's maximum health.

* Glimpse directly negates Relocate.
Additional:
* Disruptor can always Glimpse back Io or his target after he Relocated nearby.
* Even better, thanks to the indicator on the ground, you can even preemptively drop Static Storm and Kinetic Field on the spot they will relocate to.
* Thunder Strike and Glimpse are also good tools to bring back an Io that Tethered away in the fog of war.

* Glimpse moves Clockwerk away from allies struck by Hookshot, or under attack by Battery Assault.
* Static Storm can turn Power Cogs into Clockwerk's own grave, but Blade Mail will also return the damage to Disruptor.

* Heartstopper Aura can do a decent damage overtime to Chen's High-Health-Creep Army, and Chen does not have any source of burst damage to Necrophos.
* Necrophos can purchase a Spirit Vessel to provide an AOE debuff that reduce the healing from Divine Favor and Hand of God.

* Because Huskar tends to stay at low health to gain the maximum bonuses from Berserker's Blood, it makes him an exceptionally prime target for Reaper's Scythe.
Additional:
* Huskar is often at low health, making him easy prey for Reaper's Scythe.
* Ghost Shroud prevents Huskar from stacking Burning Spear, and if Heartstopper Aura stacks are active, can regenerate health lost to existing stacks.

* Reaper's Scythe can kill Alchemist before Chemical Rage has the time to heal him.
* Ghost Shroud can prevent Alchemist from attacking Necrophos, as well as make him immune to Acid Spray and Unstable Concoction damage.
* Heartstopper Aura will do damage as long as Necrophos is alive based on health percentage, which is a problem for a strength hero such as Alchemist.

* Death Pulse can easily wipe out Broodmother's spiderlings if they're too close while also offering Necrophos a source of regeneration for Broodmother's harass in lane.
* Ghost Shroud prevents Broodmother or her spiderlings from damaging Necrophos temporarily.
* Heartstopper Aura will regenerate lost health and mana for every spiderling or spiderite Necrophos manages to kill.

* Necrophos usually doesn't build much attack damage to steal from.
* He can use Ghost Shroud to prevent Razor from attacking him with the stolen damage from Static Link.
* Razor is somewhat vulnerable to magical damage, and Reaper's Scythe prevents him from escaping with his high movement speed when things get dangerous.

* Some heroes, such as Necrophos can be an issue if not initiated onto by Sven first.

Additional:
* His Heartstopper Aura deals the same gradual damage over time no matter how high Sven builds his strength or health pool up, and should he fall down to a certain percentage, his high health will no longer matter if Necrophos manages to land his Reaper's Scythe, killing him instantly. But it is best if Necrophos can either catch him off guard before he can possibly use his Black King Bar (which is an item Sven players commonly purchase), or bait him out of it.
* Ghost Shroud prevents Sven from hitting Necrophos, and if he doesn't have his Storm Hammer available, it could make him completely immune to Sven and allow Necrophos to easily kite him around.

* Heroes with detection: Bounty Hunter, Disruptor, Razor, Slardar, Spectre, Spirit Breaker

* Necrophos's Reaper's Scythe can finish off a low-health Morphling.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Dark Seer relies on Surge for most of his mobility, so he's not very vulnerable to slows, but much more to root effects and walls or pseudo-walls such as Disruptor's Kinetic Field or Slark's Pounce.

* Heroes that can negate Hoodwink's mobility: Kunkka, Disruptor, Mars.

* Reaper's Scythe and Heartstopper Aura deal percentage-based damage, ignoring Bristleback's high health.
* Heartstopper Aura's HP removal does not trigger Bristleback's passive.
Additional:
* Heartstopper Aura deals percentage-based damage flagged as HP removal, so it is not reduced by Bristleback, nor does it trigger passive Quill Sprays.
* Reaper's Scythe is very effective against Bristleback not only due to its percentage-based damage, but rather because it first stuns and then deals its damage, allowing Necrophos to position in front of Bristleback in time.

* Heartstopper Aura and Reaper's Scythe go right through Dragon Knight's armor.

* Glimpse brings Anti-Mage back after he Blinks away.
* Static Storm stops Anti-Mage from Blinking.
Additional:
* Similar to Queen of Pain, Glimpse can disable Blink, negating his mobility.
* However, Counterspell can negate a majority of Disruptor's damage, which may require him to have a partner to successfully kill Anti-Mage.

* Necrophos becomes a bigger threat the lower one's health gets, and unfortunately for Phoenix, most of its spells have noticeable health costs. Those costs, coupled with his Heartstopper Aura, means that staying in a teamfight for too long under Necrophos' presence will make Phoenix a more valid target for his ultimate, with its stun completely preventing any form of retaliation or protection. Necrophos players are also likely to buy more durability items such as Hood of Defiance, making him more able to withstand Phoenix's damage despite having no escape mechanisms.
* However, it is also important to remember that a Scepter-upgraded Supernova can help protect an ally from his ultimate.
Additional:
* Phoenix constantly depletes its own health due to the health costs of its abilities. Unlike heroes that have a similar mechanic, Phoenix does not benefit from low health, nor does it really have a countermeasure for it. As such, Phoenix is a very vulnerable target for Necrophos to prey on, especially when caught off guard before it can cast Supernova.

* Glimpse can return Tusk to where he was after using Snowball.

* Heroes with area heals prevents Bloodseeker from bringing enemies low, and therefore deny him his Thirst bonuses and health return: Necrophos, Dazzle

* Ursa struggles against heroes with strong (and especially undispellable) disables (Disruptor, Puck, Shadow Demon, Outworld Destroyer and etc).

* Riki and Disruptor: Smoke Screen and Static Storm can be thrown wherever Puck used Phase Shift, making Puck an easy target if it doesn't have Blink Dagger or is on cooldown. Puck is also very susceptible to Riki's high attack damage when attacking from the back. Glimpse also prevents Puck from escaping.