* Because Huskar tends to stay at low health to gain the maximum bonuses from Berserker's Blood, it makes him an exceptionally prime target for Reaper's Scythe.
Additional:
* Huskar is often at low health, making him easy prey for Reaper's Scythe.
* Ghost Shroud prevents Huskar from stacking Burning Spear, and if Heartstopper Aura stacks are active, can regenerate health lost to existing stacks.

* Mirror Image can cause Huskar to Life Break the wrong target.
* Rip Tide reduces Huskar's already low armor.
* Song of the Siren allows teams to recover from Huskar's initiation, as well as the damage over time from Burning Spears.

* Ensnare is good vs bear.
* In teamfights, song of the siren may be used to properly set up and coordinate an attack on Lone Druid in the backline, bursting him down, allowing to completely ignore the bear.
* Druid lack innate AoE capabilities giving him no good way of dealing with illusions.

* Ghost Shroud can be use both offensively to slow Lone Druid or Defensively to prevent Lone Druid and The Spirit Bear from attacking him.
* Heartstopper aura burns the Spirit bear High HP over time. Additionally, it can deal decent damage to Lone Druid during his True Form.

* Heartstopper Aura can do a decent damage overtime to Chen's High-Health-Creep Army, and Chen does not have any source of burst damage to Necrophos.
* Necrophos can purchase a Spirit Vessel to provide an AOE debuff that reduce the healing from Divine Favor and Hand of God.

* Illusion and heroes with summons are difficult to kill with Chen's single-target offensive spells: Terrorblade, Phantom Lancer, Chaos Knight, Broodmother, Naga Siren, Lycan, Visage. However, Chen can convert enemy summons with Holy Persuasion, as long as they don't bunch up.

Additional:
* Naga Siren can make landing Chen's combo very hard due to her being an illusion hero.
* Ensnare will prevent Chen from activating Hand of God.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Mirror Image can dispel Frostbite.
* Song of the Siren can stop Freezing Field regardless of any kind of invisibility as well as allow Naga Siren's team to quickly close the gap on Crystal Maiden.
Additional:
* Mirror Image can dispel Frostbite.
* Ensnare and Song of the Siren can stop Freezing Field.
* Song of the Siren can allow her team to quickly close the gap on Crystal Maiden.

* Heroes that have escape abilities (such as Queen of Pain, Storm Spirit or Timbersaw) can be either nullified by Reaper's Scythe or a complimentary item for Necrophos (like Rod of Atos or Scythe of Vyse). If Necrophos is quick enough and enters range, they can quickly, if not instantly, die if they are not quick enough.

* Any hero reliant of mobility, like Storm Spirit.

* Ensnare with her attacks allows Naga Siren to gank Sniper easily.
* Rip Tide removes Sniper's very little armor.

* Naga Siren is a natural split-pusher. With a Radiance equipped, she will easily out-push Nature's Prophet, farming his treants in the process.
* Ensnare prevents Teleportation. Even if he hid inside Sprout, Song of the Siren lasts long enough to prevent him from escaping.
Additional:
* Naga Siren is a natural split-pusher. With Rip Tide, she will easily out-push Nature's Prophet, farming his treants in the process.
* Ensnare prevents Teleportation. Even if he hides inside Sprout, Song of the Siren lasts long enough to prevent him from escaping.

* Heartstopper Aura is effective against high health heroes, and Pudge is no exception. Coupled with his constant self-damage from Rot, being around Necrophos could prove risky for an overconfident Pudge.
* Regardless of how much health Pudge gains through Flesh Heap, Reaper's Scythe will often kill Pudge should his health fall below 40%, making Necrophos an ideal counter versus Pudge.
Additional:
* No matter how high Pudge builds up strength with his Flesh Heap, all it needs is for him to fall below a certain percentage of health for him to fall to Reaper's Scythe. Considering his constant self-damage with Rot, being around Heartstopper Aura will prove risky for an overconfident Pudge.

* Due to Doom's naturally high health, strength gain and common itemization for durability, Heartstopper Aura is particularly effective. The health loss is also large enough that, throughout all stages of the game, the aura effectively neuters the health regeneration granted by Devour.
* Necrophos can help to keep both himself and his allies alive during Doom through his natural regeneration granted by Heartstopper Aura (which is not disabled by Doom), or in the case of an ally, through his Death Pulse. Additionally, Necrophos is an ideal Mekansm carrier. Should one be bought, kills against Necrophos' team can be difficult to secure due to the damage-over-time nature of Doom and his abilities.
* Doom typically wants to be a hero that soaks attention from the enemy team and takes the role of an initiator and disabler. As such, Doom is an ideal target for Reaper's Scythe, as it is likely Doom will be at the fore-front of any fight.

* Necrophos' largely magical damage completely ignores Bulwark.
* Ghost Shroud protects Necrophos from God's Rebuke but more importantly stops Mars from being a threat in lane.

* Reaper's Scythe can kill Alchemist before Chemical Rage has the time to heal him.
* Ghost Shroud can prevent Alchemist from attacking Necrophos, as well as make him immune to Acid Spray and Unstable Concoction damage.
* Heartstopper Aura will do damage as long as Necrophos is alive based on health percentage, which is a problem for a strength hero such as Alchemist.

* Song of the Siren can be used to nullify the effects of Winter's Curse, and when upgraded with Aghanim's Scepter it also outmatches the heal of Cold Embrace.
* If Winter Wyvern is reckless enough to put an ally in Cold Embrace, Naga Siren will be able to use her Ensnare to extend the disable on the hero affected by Cold Embrace.

* Reaper's Scythe can kill Terrorblade quickly before he has chance to use Sunder.
* Ghost Shroud protects Necrophos against Terrorblade's high attack damage.

* No matter how Tidehunter builds tanky items such as (Guardian Greaves, Crimson Guard or Pipe of Insight), all it needs is for him to fall below a certain percentage of health for him to fall to Reaper's Scythe.

* Song of the Siren stops him from acting and her illusions can push better than him because Mirror Image has a longer duration.
* Arc Warden does not often build Radiance, which is useful for illusions and countering illusion pushes.
* Mirror Image dispels Flux or prevents Flux's slow.
Additional:
* Her illusions can push better than Arc Warden's Tempest Double because Mirror Image has a longer duration.
* Mirror Image dispels Flux, and the illusions stop Flux from working.

* Mirror Image can be effective since Night Stalker cannot withstand fighting Illusions. If he's unable to tell which Naga Siren is real, he will have a hard time landing his Void and Crippling Fear.
Additional:
* Ensnare and Song of the Siren prevents Night Stalker from escaping and ganking during daytime or even nighttime.
* Rip Tide reduces Night Stalker's armor, making him easier to focus down.
* Mirror Image can be effective against Night Stalker, due to his single target abilities.

* Necrophos is a dangerous opponent to go against with. Regardless of how many strength Undying has gained from Decay, Necrophos can finish off Undying with Reaper's Scythe once Undying's HP falls below a certain threshold.
* Heartstopper Aura will do more damage to Undying if he gained strength from Decay, as it does damage based on a hero's maximum health.

* Necrophos usually doesn't build much attack damage to steal from.
* He can use Ghost Shroud to prevent Razor from attacking him with the stolen damage from Static Link.
* Razor is somewhat vulnerable to magical damage, and Reaper's Scythe prevents him from escaping with his high movement speed when things get dangerous.

* Reaper's Scythe and Heartstopper Aura deal percentage-based damage, ignoring Underlord's high health.

* Death Pulse can easily wipe out Broodmother's spiderlings if they're too close while also offering Necrophos a source of regeneration for Broodmother's harass in lane.
* Ghost Shroud prevents Broodmother or her spiderlings from damaging Necrophos temporarily.
* Heartstopper Aura will regenerate lost health and mana for every spiderling or spiderite Necrophos manages to kill.

* Necrophos's Reaper's Scythe can finish off a low-health Morphling.

* Lycan is a carrier built entirely with physical attacks, having 0 AoE presence and no spell power. Due to this, he can't deal with illusions or Naga Siren's Ensnare.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

* Naga Siren with Mirror Image
* Heroes that can dodge Glimpse:
* Puck with Phase Shift
* Riki with Tricks of the Trade
* Phantom Lancer with Doppelganger
* Ember Spirit with Sleight of Fist and Activate Fire Remnant
* Chaos Knight with Phantasm
* Naga Siren with Mirror Image
* Tusk with Snowball
* Juggernaut with Omnislash
* Brewmaster with Primal Split
* Lifestealer with Infest
* Phoenix with Supernova

* Heroes with summons like Broodmother,Enigma, Invoker, Nature's Prophet, Lycan, Visage;or illusions, like Naga Siren, Phantom Lancer, Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity mines in the early game.

* Heroes that have escape abilities (such as Queen of Pain, Storm Spirit or Timbersaw) can be either nullified by Reaper's Scythe or a complimentary item for Necrophos (like Rod of Atos or Scythe of Vyse). If Necrophos is quick enough and enters range, they can quickly, if not instantly, die if they are not quick enough.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Heroes with illusions: Chaos Knight, Naga Siren, Phantom Lancer

* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

Additional:
* Ensnare disables Lanaya's invisibility and Blink Dagger (a core item on Templar Assassin), and her illusions will break Refraction easily.

* Naga Siren with Mirror Image
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

Additional:
* Bounty Hunter is a single target dealer, so he will not fare well against Naga Siren. He might as well try to Track her, but her Mirror Image will dispel the effect. Also, Ensnare reveals invisible units while they're rooted, putting Bounty Hunter in a tricky situation.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King.

* Heroes that have high health but little to no magic resistance are easy prey for Necrophos, as no matter how high they build their health up, Reaper's Scythe will kill them outright as long as they fall under a certain threshold, and Heartstopper Aura will deal the same amount of damage regardless, decaying their health the longer they stay within range. As such, Strength heroes like Chaos Knight, Centaur Warrunner or Magnus are good targets for his ultimate.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Illusion heroes like the aforementioned Phantom Lancer or Naga Siren, or heroes that tend to buy Manta Style, like Luna or Juggernaut, will give Slardar a hard time, as his damage is single-targeted.

* Illusion-based and multi-unit heroes can take advantage of Chaos Knight's lack of area damage: Naga Siren, Phantom Lancer, Meepo, Broodmother

* Heroes that have high health but little to no magic resistance are easy prey for Necrophos, as no matter how high they build their health up, Reaper's Scythe will kill them outright as long as they fall under a certain threshold, and Heartstopper Aura will deal the same amount of damage regardless, decaying their health the longer they stay within range. As such, Strength heroes like Chaos Knight, Centaur Warrunner or Magnus are good targets for his ultimate.

* Reaper's Scythe and Heartstopper Aura deal percentage-based damage, ignoring Bristleback's high health.
* Heartstopper Aura's HP removal does not trigger Bristleback's passive.
Additional:
* Heartstopper Aura deals percentage-based damage flagged as HP removal, so it is not reduced by Bristleback, nor does it trigger passive Quill Sprays.
* Reaper's Scythe is very effective against Bristleback not only due to its percentage-based damage, but rather because it first stuns and then deals its damage, allowing Necrophos to position in front of Bristleback in time.

* With high health and rarely buying Linken's Sphere or Black King Bar, Centaur Warrunner is a good target for Reaper's Scythe. However, Centaur Warrunner can resolve this problem by buying Pipe of Insight or Hood of Defiance to diminish its damage.
* Heartstopper Aura will do well against high health heroes such as Centaur Warrunner.

* Song of the Siren lasts long enough to prevent a successful Duel (but only if Naga wasn't the target).

* Necrophos becomes a bigger threat the lower one's health gets, and unfortunately for Phoenix, most of its spells have noticeable health costs. Those costs, coupled with his Heartstopper Aura, means that staying in a teamfight for too long under Necrophos' presence will make Phoenix a more valid target for his ultimate, with its stun completely preventing any form of retaliation or protection. Necrophos players are also likely to buy more durability items such as Hood of Defiance, making him more able to withstand Phoenix's damage despite having no escape mechanisms.
* However, it is also important to remember that a Scepter-upgraded Supernova can help protect an ally from his ultimate.
Additional:
* Phoenix constantly depletes its own health due to the health costs of its abilities. Unlike heroes that have a similar mechanic, Phoenix does not benefit from low health, nor does it really have a countermeasure for it. As such, Phoenix is a very vulnerable target for Necrophos to prey on, especially when caught off guard before it can cast Supernova.

* Song of the Siren completely wastes Abaddon Borrowed Time while keeping him in place.
* Naga Siren is able to simply dispel Abaddon's Curse of Avernus with Mirror Image before getting hit 4 times consecutively.
* Although Naga Siren's illusions can be easily destroyed by Aphotic Shield, Naga Siren can resolve that issue easily by purchasing Heart of Tarrasque to drastically increase her tankiness. Plus, the said item makes Naga Siren harder to be distinguished from her illusions.

* Song of the Siren can be used to time out Guardian Angel, giving Naga Siren's team an easy opportunity to counter-initiate.
Additional:
* Song of the Siren will waste Guardian Angel.
* Ensnare fully works on Heavenly Graced targets. However, Ensnare is dispellable with any dispel, and so can be dispelled by Heavenly Grace.
* As an agility hero that relies on illusions, Naga is one of the most natural Diffusal Blade carriers, the bane of every hero with a small mana pool.

* Death Pulse can single out Spectre from her illusions, as well as heal his team against her. He also usually stands close to his allies for Death Pulse, effectively disabling Desolate.

* Heroes who rely on physical damage are easily negated by Ghost Shroud: Phantom Assassin, Wraith King, Juggernaut.

* Heroes with summons and illusions such as Broodmother and Naga Siren, are ill-suited for Wraith King to fight, as he has no source of waveclear.

* Heroes who rely on physical damage are easily negated by Ghost Shroud: Phantom Assassin, Wraith King, Juggernaut.

* Illusion-based heroes are effective against Omnislash and Juggernaut's single-targeted damage: Naga Siren, Chaos Knight, Terrorblade,Phantom Lancer.

* Heroes that create illusions (such as Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress and the aforementioned Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. (However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse).

* A couple of long-range heroes with excellent laning like Mirana, Lina, Necrophos, Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.

* Reaper's Scythe will turn Tiny's high health against him.
* Heartstopper Aura does substantial damage to Tiny as a result of his high max health.

* Song of the Siren is very difficult for Rubick to Spell Steal when he is affected by sleep.
* Ensnare and Rip Tide together with some attacks can take Rubick down quickly, due to his low health pool and armor.
* Naga Siren usually buys Diffusal Blade, which will prevent Rubick from spamming his abilities from Spell Steal.
* Mirror Image allows to dodge the incoming stun from Telekinesis (when she is not a target) and it can also to dodge and dispel Fade Bolt's damage reduction debuff.

* Heroes with powerful rooting abilities will disable most of Pangolier's skill, a bonus point if it pierce spell immunity since it will also be able to stop Pangolier during his Rolling Thunder: Treant Protector, Meepo, Crystal Maiden, Dark Willow, Underlord, Naga Siren

* Mirror Image's illusions can easily walk straight at Dazzle and attack him, due to Dazzle's lack of reliable AoE nukes or disables.
* Ensnare roots Dazzle or his allies, making it harder to stay range of Dazzle's saving abilities.
* Song of the Siren can be used to initiate a fight with superior positioning, potentially zoning Dazzle's high-impact spells out of the fight.

* Heroes with magical burst damage can often kill Phantom Assassin before she gets to do much: Necrophos, Nyx Assassin, Gyrocopter.

* Heartstopper Aura effectively negates Timbersaw's large HP pool as well as HP regen.
* Death Pulse together with health and mana regeneration from killed creeps helps Necrophos and his teammates survive Timbersaw's burst damage.
* As a tanky hero that stays in the middle of teamfights, Timbersaw is an easy target for Reaper's Scythe.

* Illusion heroes, such as Naga Siren, Phantom Lancer, Chaos Knight, Terrorblade will become strong against Tinker in the late game when Tinker's only area of effect damage, March of the Machines, ceases to kill illusions quickly. Without Aghanim's Scepter Tinker is forced to defensively disarm heroes with Laser, leaving illusions free to deal physical damage which Tinker's low armor makes highly effective. In addition, Mjollnir or Battle Fury, two common pickups against illusion heroes, don't work well on Tinker at all.

* Frequent healing from Death Pulse and Mekansm makes it difficult for Axe to finish off targets with Culling Blade.
* Ghost Shroud's instant cast time allows Necrophos to turn ethereal before being initiated on by Berserker's Call. This prevents him from attacking Axe while taunted, thus lowering the chance to proc Counter Helix.
* Axe's high health is relatively ineffective against Heartstopper Aura's percentage-based health degeneration.
* Reaper's Scythe negates Axe's tankiness, and can kill him quickly after initiation.
Additional:
* Frequent healing from Death Pulse makes it difficult for Axe to finish off targets with Culling Blade.
* Reaper's Scythe negates Axe's tankiness, and can kill him quickly after initiation.
* Heartstopper Aura is effective due to Axe's high strength gain.

* Frequent healing from Death Pulse and Mekansm/Guardian Greaves or Pipe of Insight makes it difficult for Earthshaker to execute his combo with Echo Slam.
* Necrophos usually buys Radiance to improve their burning aura damage from Heartstopper Aura will usually disable Earthshaker's Blink Dagger prior to a teamfight, preventing him from initiating or re-initiating.
* Reaper's Scythe allows to kill  Earthshaker while he blinks in, preventing him from executing his combo (although Earthshaker is rarely a primary target).

* Naga Siren can easily disjoint, and dispel Corrosive Skin with Mirror Image.
* Since Viper is a single-target hero, he will not stand a chance against Naga Siren because she is an illusion based hero.

* Some heroes, such as Necrophos can be an issue if not initiated onto by Sven first.

Additional:
* His Heartstopper Aura deals the same gradual damage over time no matter how high Sven builds his strength or health pool up, and should he fall down to a certain percentage, his high health will no longer matter if Necrophos manages to land his Reaper's Scythe, killing him instantly. But it is best if Necrophos can either catch him off guard before he can possibly use his Black King Bar (which is an item Sven players commonly purchase), or bait him out of it.
* Ghost Shroud prevents Sven from hitting Necrophos, and if he doesn't have his Storm Hammer available, it could make him completely immune to Sven and allow Necrophos to easily kite him around.

* Heroes with area heals prevents Bloodseeker from bringing enemies low, and therefore deny him his Thirst bonuses and health return: Necrophos, Dazzle