* Mana Burn completely drains Pudge's little mana which may render Meat Hook & Dismember unusable.
* Impale and Spiked Carapace used to cancel Dismember if timed perfectly.
* Vendetta grants Nyx Assassin invisibility and a high degree of mobility for a long time, which can make Nyx a difficult target to hook. In addition, it also scouts out Pudge's location and surprising him with his attack, Impale and Mana Burn.

* The percentage-based primary-attribute reduction effect of Whirling Death can be devastating for Pudge due to his high strength gain through Flesh Heap.
* Reactive Armor's health regeneration and common itemization for magic resistance and durability make Timbersaw a poor target for Pudge.
* Timber Chain's high mobility makes Timbersaw difficult to lockdown for Pudge, given he only has one reliable disable.

* With Timber Chain, Timbersaw can slow, catch up with, or escape from Chen and his creeps.
* Chakram can clear Chen's creeps and slow him.
* Attacks from multiple creeps quickly build Reactive Armor stacks.

* Heroes with damage burst can often kill Chen or his allies before he can use Hand of God: Lina, Techies, Shadow Fiend, Pugna, Nyx Assassin.

* Reactive Armor helps Timbersaw sustain harassment from Stifling Dagger, as well as ganking attempts.
* Phantom Assassin is a hero with moderate HP pool, and usually appears in the front line of battle. Because Blur does nothing against spells, she is vulnerable to Timbersaw's skills.
* Timbersaw can easily escape from Phantom Assassin thanks to his Timber Chain.
Additional:
* Reactive Armor helps Timbersaw sustain harassment from Stifling Dagger.
* Phantom Assassin has a moderate health pool and usually appears in the front line of battle, making her vulnerable to Timbersaw's magic burst.
* Timbersaw can easily escape from Phantom Assassin thanks to his Timber Chain.

* Ethereal state disarms the target and makes them more vulnerable to magic damage, both of which Phantom Assassin despises. Especially Pugna and any hero that is wielding Ethereal Blade, such as Mirana, Nyx Assassin or Morphling.

* The burst damage from Timbersaw's abilities is more than enough to deal with Enchantress and her creeps.
* Timbersaw doesn't rely on his physical attacks, which makes Untouchable useless against him.
* Timber Chain can close the gap between them and minimize damage from Impetus.
* Be aware, however, that Timber Chain could work against him if used to escape.
* However, Impetus can ignore Reactive Armor if Enchantress is not a primary target for Timbersaw or if he is disabled.

* Vendetta breaks Untouchable and deals great damage against her.
* Enchantress' lack of mobility makes her a primary target for ganking with Vendetta.
* Spiked Carapace can reflect Impetus and stun Enchantress.
* Mana Burn can deal tremendous damage against her due to being an Intelligence hero.
Additional:
* Vendetta disables Untouchable.
* Spiked Carapace reflects the damage from Impetus.
* Enchantress is a rather squishy hero, making her fall easily to Nyx Assassin's high burst damage.

* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin

* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe

Additional:
* Timbersaw can easily cut down trees from Sprout, making it very difficult for Nature's Prophet to teleport away or trap enemies.
* Timbersaw's abilities quickly clear out treants.
* Reactive Armor negates most of the damage of Nature's Prophet's treants, and Timbersaw can often allow himself to be attacked in order to heal himself.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Heroes with break abilities: Nyx Assassin, Shadow Demon (with Aghanim's Scepter), Viper.

* Mana Burn is strong against Keeper of the Light due to his high mana pool.
* Spiked Carapace can be used to reflect Illuminate damage and stun Keeper of the Light.
* Vendetta allows Nyx Assassin to follow Keeper of the Light around if he tries to split-push.

* Whirling Death deals damage as well while reducing 15% of Bristleback's strength, which reduces Bristleback's tankiness.
* Reactive Armor can sustain through multiple Viscous Nasal Goo and Quill Spray stacks.
* Timber Chain makes it hard for Bristleback to slow down Timbersaw with Viscous Nasal Goo.

* Timbersaw is often too mobile and durable for Gyrocopter to bring down with his area attacks.

* Nyx can walk into Firefly with Spiked Carapace and stun Batrider if he has no Spell Immunity.

* Assassinate is easy to reflect with Spiked Carapace for massive damage.
* Shrapnel's area damage can set up an easy stun with Spiked Carapace, especially when combined with Vendetta.
* In the early game, Sniper's low health pool and high intelligence makes him easy prey for Nyx Assassin.

* Timbersaw can take down Terrorblade's illusions with his area damage burst.
* Reactive Armor plus another armor item reduce much of Terrorblade's damage.
Additional:
* Timbersaw's spell combos all deal magical and pure damage, completely ignoring Terrorblade's high base armor and clearing his illusions very quickly due to the AoE damage.
* Reactive Armor negates most of Terrorblade's damage against Timbersaw, and its high health regeneration and armor bonuses can help Timbersaw survive after being Sundered.

* All Timbersaw's abilities are AOE pure damage and can easily deal with Phantom Lancer's illusions
* Reactive Armor highly negates Phantom Lancer's physical damage, making him having a hard time killing Timbersaw.
Additional:
* Phantom Lancer's lack of burst damage and constant attacks will increase Reactive Armor to max level immediately. Coupled with Timber Chain making escaping from crowds easy, it is almost impossible for Timbersaw to be killed by Phantom Lancer.
* Whirling Death and Chakram can instantly destroy large groups of illusions, negating Phantom Lancer's advantage.

* Because multiple Meepos tend to clump up, they present an easy target for Timbersaw's many area abilities.

* With her passive Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious Stone Gaze.
* Mana Burn quickly destroys Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Additional:
* Level 4 Mana Burn burns 38,5% of Medusa's mana every 4 seconds if Medusa only increases her mana pool with intelligence. Additionally, 60% of the Mana Burn damage gets mitigated by Mana Shield, burning even more mana.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.

* Mana Burn does tons of damage against Lina because of her high intelligence. The mana burn also prevents Lina from casting her full combo.
* Spiked Carapace can easily be used to counter Lina's abilities because of their long cast animation, and could probably kill Lina outright if Laguna Blade is reflected.

* Heroes that can close the gap can easily chase her down, such as Timbersaw with Timber Chain and Anti-Mage with Blink.

* Timbersaw's innate tankiness is very hard to deal with as Naga Siren. Timbersaw's high Pure Damage and spammable AoE nukes can also destroy Naga Siren's illusions very fast.

* Whirling Death reduces Axe's strength by 15%, making him much less tanky, especially in the early game. It is also stackable.
* Axe's Blade Mail is ineffective against attribute changes, and Timbersaw's mobility with Timber Chain means he can wait out Blade Mail's duration.
* Reactive Armor's armor and regeneration makes it much harder for Axe to finish Timbersaw with Culling Blade.
* Chakram disarms Timbersaw, making Counter Helix less effective.

* Spiked Carapace stops Snapfire's Mortimer Kisses.
* Snapfire's low armor and agility gain means that Vendetta will deal a decent amount of damage.

* Timber Chain can kite Troll Warlord extremely effectively.
* Whirling Death and Chakram deals lots of damage to Troll Warlord.
* Reactive Armor makes Timbersaw extremely resilient to Troll's attack damage and extreme attack speed, especially during Battle Trance.

* Timbersaw relies on dealing massive amounts of pure damage, making Cold Embrace a good setup for his nukes.
* If he has Reactive Armor stacks, Timbersaw can tank the damage from his allies if he is targeted by Winter's Curse. If he's not the target, Timbersaw's abysmal attack damage will contribute next to nothing when he is cursed to attack an ally.

* Razor deals mostly physical damage towards the later game, and Timbersaw is also very mobile, making him a difficult kill to earn.
* Timbersaw rarely resorts to attacks, thus does not suffer when his damage is stolen with Static Link.

* Reactive Armor helps Timbersaw to endure the damage from Chaos Bolt and Reality Rift combo.
* Timbersaw's large amount of pure damage AoE nukes clears Chaos Knight's illusions quickly, drastically reducing his damage.
Additional:
* Strong area damage, particularly from Whirling Death and Chakram, lets Timbersaw clear out illusions quickly.
* Whirling Death directly reduces Strength from both Chaos Knight and his Phantasm illusions, reducing both the damage output and raw health that the hero relies on.
* Reactive Armor quickly builds stacks against Phantasm illusions, making Timbersaw hard to kill.
* Timber Chain allows Timbersaw to escape while surrounded.

* Many of Nyx Assassin's abilities are good against Windranger.
* Impale is great for stunning Windranger and allowing additional disables to be landed.
* Mana Burn is useful against Windranger's decent intelligence growth and also burns some mana, preventing her from using more abilities.
* Spiked Carapace is easy to use against Powershot.
* Vendetta allows Nyx Assassin to sneak up on and deal massive damage to Windranger without giving Windranger a chance to use Windrun to evade it.
* Nyx Assassin's item build allows him to easily deal with Windranger.

* Mana Burn can instantly deplete Tidehunter's low mana pool, especially in the early game, potentially preventing Tidehunter from casting Ravage.
* Ravage's travel time allows Nyx Assassin to easily stun Tidehunter with Spiked Carapace.
* Vendetta offers a very rare break effect, which fully disables Kraken Shell and makes Tidehunter susceptible to follow-up disables.

* Reactive Armor is very effective against Beastmaster's summons during laning stage and entire game.
* Timbersaw can quickly clear Beastmaster's summons with his nukes.

* Crystal Maiden has a very bad movement speed, so Impale is easy to land against her. Furthermore, even while trapped by Frostbite, Nyx Assassin can still cast Impale.
* Crystal Maiden has very low armor, so Vendetta is very effective.
* Nyx Assassin has two ways to stop Freezing Field, provided she doesn't get a Black King Bar. He can pop Spiked Carapace and simply walk into the field, or he can use Impale to interrupt the field, since Crystal Maiden has to channel it.
Additional:
* Spike Carapace easily interrupts Freezing Field.
* Frostbite's damage over time sets up an easy Spiked Carapace stun.
* Crystal Maiden is extremely fragile and dies quickly to Nyx Assassin's burst damage.

* Impale interrupts Upheaval.
* Nyx Assassin Vendetta allows him to escape from Warlock's Upheaval with maximum move speed.
* Warlock's low health pool and mobility can easily take down by Nyx Assassin's burst damage.

* Not only are all of Timbersaw's active abilities capable of cutting down trees, but Whirling Death and Timber Chain also require it to be effective, counteracting both Treant Protector's Nature's Guise and Eyes in the Forest abilities.
Additional:
* Timbersaw can use his plethora of tree cutting abilities to level entire sections of the forest, making hiding in the trees more difficult for Treant Protector and his team.
* Timbersaw can easily cut down Treant Protector's Eyes In The Forest once his team has detection. He may even do it unknowingly due to the sheer destructive and chaotic nature of his abilities.

* Vendetta disables Vengeance Aura and allows him to attack Vengeful Spirit with Impale and Mana Burn.
* Spiked Carapace is easy to use against a Wave of Terror or Magic Missile.

* Nyx Assassin has a lot of burst damage from his Impale, Mana Burn, Dagon, and the bonus damage from Vendetta. All of this damage is enough to kill Drow Ranger.
* Nyx Assassin is usually invisible most of the time thanks to his ability Vendetta, which allows him to gank Drow Ranger easily.

* Spiderlings deal almost no damage against Reactive armor. They also die quickly from Timbersaw's AoE abilities.
* Broodmother has no mobility ability except the movement speed buff from Spin Web, allowing Timbersaw to easily escape her Incapacitating Bite with Timber Chain.
* Timbersaw's tree-cutting abilities makes it difficult for Broodmother to hide, especially near the edges of the map.
Additional:
* Reactive Armor prevents Broodmother's spiderlings from being able to effectively harass Timbersaw in the lane.
* Timber Chain's high mobility makes Incapacitating Bite's slow irrelevant.
* Timbersaw's abilities can destroy any trees that Broodmother attempts to hide in and his AoE abilities can quickly clear her Spiderlings.

* Timbersaw's ability to destroy trees can be a serious problem for some heroes that use them, as either a way of enhancing their spells like Treant Protector, or heroes that tend to hide inside of them like Tinker and Monkey King.

* His whole skillset acts like a counter to Tinker:
* Impale prevents Tinker from blinding Nyx Assassin or fighting back, while giving Nyx' allies time to catch up to Tinker's position.
* Mana Burn generally deals more damage to intelligence based heroes like Tinker
* Spiked Carapace can stun Tinker at a moment of Nyx Assassin's choosing if March of the Machines has been cast. It is also quite easy to time Spiked Carapace against Heat Seeking Missiles.
* Vendetta allows Nyx to approach Tinker in the trees or wait for him in common hiding spots and deal heavy damage to his low armor.
Additional:
* March of the Machines and Heat-Seeking Missile allow easy Spiked Carapace stuns.
* As a fragile hero that relies on mana and intelligence items, Tinker is vulnerable to Mana Burn.
* Nyx Assassin's stuns can interrupt Rearm and leave Tinker helpless.

* Heroes with high burst damage: Lina, Lion, Luna, Nyx Assassin, Queen of Pain.

* Heroes that can pick you off: Clinkz, Nyx Assassin, Puck, Riki.

* Silence (and mana burns) will be a persistent problem for Phoenix, as it is heavily reliant on its abilities whether defensively or offensively, so heroes like Death Prophet, Skywrath Mage, and even Nyx Assassin must be closely observed to prevent being shut down by these heroes.
* Hexes are a greater threat to Phoenix as they also disable items, preventing Phoenix from dispelling the debuff on its own.

Additional:
* Spiked Carapace reacts on any of the damage over time from Phoenix's abilities and can interrupt Sun Ray and Icarus Dive.

* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin

* Timbersaw: Lone Druid will have a hard time dealing with Timbersaw due to his tankiness and high Armor from Reactive Armor

* Nyx Assassin can reflect Life Break with Spiked Carapace.

* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom

* Heroes who are not easily crippled by Fate's Edict or Fortune's End, such as Timbersaw, or those who can dispel them, such as Phantom Lancer, can kill Oracle unhindered.

* Reactive Armor makes Timbersaw very effective against heroes that control a lot of units, such as Broodmother, Lycan and Undying.

* Enigma is fragile, and lacks escapes, being dependent on Blink Dagger for mobility. Ganking Heroes or Heroes with burst damage will likely kill him before he can do anything. Such Heroes include: Lina, Lion, Puck, Slark, Nyx Assassin, etc.

Additional:
* Enigma's uncontrollable damage from Malefice and Midnight Pulse make him easy to stun with Spiked Carapace.
* Black Hole can be easily interrupted by Impale or Spiked Carapace.

* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom

* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom

* Nyx Assassin can take advantage of every one of Puck's weaknesses. His entire skill set is very effective in countering Puck.
* Because Illusory Orb is such a slow moving projectile, Nyx Assassin can simply walk into the orb and activate Spiked Carapace, stunning Puck and setting up an easy Impale. This can be circumvented by using Phase Shift while the orb is traveling, however, that means that Puck cannot use Phase Shift to dodge any other skill nor use it to safely blink away from a fight.
* Puck is an intelligence hero that likes to build intelligence items such as Eul's Scepter of Divinity, Scythe of Vyse, and Dagon. This makes Mana Burn that much more deadly against Puck.
* An ill-timed Phase Shift can easily set himself up to be stunned by Impale.
* Puck's low base armor and below average agility gain means he is always susceptible to Vendetta.
Additional:
* Illusory Orb is easy to reflect with Spiked Carapace, either stunning Puck and setting up an easy Impale or forcing a premature Phase Shift.
* Puck is an intelligence hero that tends to build intelligence items, making it vulnerable to Mana Burn.
* An ill-timed Phase Shift can easily set Puck up to be stunned by Impale.
* Puck's low base armor and below average agility gain mean it is always susceptible to Vendetta.

* Timbersaw can use Chakram as a scouting tool to find Slark if he tries to Pounce into the trees.
* None of Timbersaw's abilities require a target to be cast, allowing him to hit Slark inside Shadow Dance.
* Reactive Armor can be effective protection against a Slark who attacks quickly, since the strong armor and health regen cannot be stolen by Essence Shift.
* Timber Chain makes Timbersaw very mobile, meaning he is among the very few heroes who can actually give chase to a fleeing Slark.

* A good Nyx can reflect Queen of Pain's Sonic Wave with his Spiked Carapace, or even initiate a gank on her in Vendetta while she farms a creep wave with Scream of Pain.
* Her strength to intelligence ratio is bad enough that he should be able to kill her without even requiring a Dagon, provided he can get his full combo off.

* Nyx Assassin's Spiked Carapace will stun Leshrac when hit by any of his AOE abilities.
* Mana Burn deals high damage due to Leshrac's high intelligence gain and burns a large amount of Leshrac's essential mana pool.

* Spiked Carapace allows Nyx to get an easy long-duration stun on Weaver once he uses Shukuchi, and then he can follow up with Impale.
* Vendetta works as a great setup for both Impale and Spiked Carapace and can deal decent damage to Weaver. Additionally he can neutralize The Swarm beetles due to his invisibility duration.

* With Vendetta, Nyx Assassin can move closely to Ember Spirit when he's farming with his Flame Guard and use Spiked Carapace with Impale to provide a reliable and long disable.
* Mana Burn is also good, as Ember Spirit relies on his limited mana pool for the early to midgame.
Additional:
* Spiked Carapace can be easily triggered by Flame Guard or Battle Fury, setting up a deadly Impale.

* Timbersaw can easily cut down the tree that Monkey King is standing on, stunning him for a lengthy period.
* Timbersaw can use Timber Chain to easily escape Wukong's Command and Primal Spring's slow.
Additional:
* Timbersaw's low cooldown and low mana cost abilities destroys the trees that Monkey King depends on.
* Timber Chain allows Timbersaw to escape Wukong's Command.

* Outworld Devourer's high intelligence gain and fragility makes him an easy target for a massive Mana Burn, as well as killing him outwards with Nyx Assassin's high burst damage.
* Astral Imprisonment can be easily exploited by Nyx Assassin with his abilities. As long as Astral Imprisonment was not cast on Nyx Assassin, it will make an opportunity for an easy stun, either by Spiked Carapace (if Outworld Devourer hid his allies or your allies) or Impale (if he hid himself). If Astral Imprisonment was cast on Nyx Assassin, using Spiked Carapace while banished will proc the stun after the disable, since Spike Carapace has a 0 second cast time and Astral Imprisonment deals damage right after the disable ends.
* An ill-timed Sanity's Eclipse or well timed Spiked Carapace can deal a lot of damage to Outworld Devourer and stun him, unless Outworld Devourer used Black King Bar beforehand.
Additional:
* Outworld Devourer's high mana pool, high intelligence, and low health makes him a prime target for Mana Burn.
* If timed correctly, Spiked Carapace will return the full damage from Sanity's Eclipse back to Outworld Devourer. Even a reflected Arcane Orb can deal significant damage and make him vulnerable to a follow-up from Nyx Assassin.
* Spiked Carapace is also the perfect tool against Astral Imprisonment: if used on Nyx, he can reflect the damage back as he comes out of the prison by casting the ability while imprisoned; if used on any other target, Nyx can come and stand close to it and use it to reflect the damage.

* Timbersaw's pure damage will kill Dragon Knight surprisingly fast, especially if he gets caught in a bad position while laning.

* Once you've taken a point in Retaliate, Nyx can easily initiate on you: he can use Spiked Carapace and hit you with Vendetta. The damage from Retaliate will be reflected back to you, stunning you with no chance to react after he's revealed himself, and should guarantee a successful Impale.

* Silencer is rather squishy and has poor mobility without items, making him an easy target for Nyx.
* Mana Burn will deal increasing damage for each 2 points of intelligence Silencer has stolen, turning Silencer's intelligence steal against him.

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* Skywrath Mage's low health makes him rather easy prey for Nyx Assassin and his lack of armor generally means he'll take the full brunt of a Vendetta strike.
* Mana Burn is annoying at all stages of the game as it turns Skywrath Mage's high intelligence growth against him.
* Spiked Carapace gives Nyx some degree of protection against Skywrath's spells.

* Due to Pugna's incredible intelligence growth and terrible strength growth, Nyx should always be able to take you out with his combo, with or without an added Dagon. Mana Burn will deal a large amount of damage in particular, especially in the late game.
* Spiked Carapace is also a great tool versus Pugna. A good player will wait for you in Vendetta until you farm a creep wave with Nether Blast and reflect it back at you as their initiation and setup for Impale.
Additional:
* Nether Blast's animation makes it easy to time Spiked Carapace for a stun.
* Pugna has the largest intelligence gain in the game, making him a prime target for Mana Burn.
* Pugna needs to channel Life Drain, making him easy to hit with Impale.

* Mana Burn is capable of removing most of Storm Spirit's large mana pool, along with dealing heavy damage and quickly depleting his chances of escaping a gank or fight.
Additional:
* Mana Burn removes much-needed mana for Ball Lightning.
* Spiked Carapace triggers on Static Remnant for an easy stun.

* Reactive Armor will quickly stack up from Familiar attacks, making Timbersaw hard to kill.
* Visage's low mobility makes it easy for Timbersaw to line up his abilities.

* Nyx Assassin's high burst damage can be the bane of Dark Willow, as her low health makes it difficult to survive long enough to escape through Shadow Realm.
* Spiked Carapace can be triggered by walking deliberately into Bramble Maze, leaving Dark Willow stunned and defenseless.

* The huge physical damage taken from Vendetta will force Necrophos to use Ghost Shroud, which is good for a followup with Dagon and Ethereal Blade, both of which are common items on Nyx Assassin.
* Using Ghost Shroud also sets Necrophos up for a Mana Burn or Impale.