* Vendetta breaks Untouchable and deals great damage against her.
* Enchantress' lack of mobility makes her a primary target for ganking with Vendetta.
* Spiked Carapace can reflect Impetus and stun Enchantress.
* Mana Burn can deal tremendous damage against her due to being an Intelligence hero.
Additional:
* Spiked Carapace reflects the damage from Impetus.
* Enchantress is a rather squishy hero, making her fall easily to Nyx Assassin's high burst damage.

* Battle Trance and Fervor can help cancel out Untouchable.
Additional:
* Untouchable's attack speed slow is easily remedied by Fervor stacks and Battle Trance.
* Troll Warlord is a natural Silver Edge carrier, disabling Enchantress' Untouchable.

* Nyx Assassin deals large amounts of pure damage with Vendetta and magical damage with Impale and Mana Burn, allowing him to ignore Terrorblade's armor and burst his low health pool down before he can use Sunder.
* Nyx Assassin commonly buys Urn of Shadows, Dagon and Meteor Hammer which deal magic damage that ignore Terrorblade's armor.
* Mana Burn might drain too much mana for Terrorblade to be able to use Sunder if he isn't careful in the early to mid game.

* Terrorblade cannot go one on one against Troll Warlord as Troll Warlord will overwhelm him faster than the other way around thanks to Whirling Axes (Melee) that will cause his attacks to miss, and Fervor that can give Troll Warlord huge amounts of attack speed to outmatch Terrorblade, even during Metamorphosis.
* Troll Warlord's high attack speed from Fervor combined with Skull Basher and Abyssal Blade means that Terrorblade will have almost no chance to use Sunder to save himself.
* Even if Terroblade manages to use Sunder on Troll Warlord, Troll Warlord will simply be able to nullify it's effect with Battle Trance.
Additional:
* Terrorblade cannot go one on one against Troll Warlord as Troll Warlord will overwhelm him faster than the other way around thanks to Whirling Axes (Melee) that will cause his attacks to miss, and Fervor that can give Troll Warlord huge amounts of attack speed to outmatch Terrorblade, even during Metamorphosis.
* Troll Warlord's high attack speed from Fervor combined with Skull Basher and Abyssal Blade means that Terrorblade will have almost no chance to use Sunder to save himself.
* Even if Terroblade manages to use Sunder on Troll Warlord, Troll Warlord will simply be able to nullify it's effect with Battle Trance.
* Overall, any attempt for Terrorblade to engage and kill Troll Warlord will hurt him more than the other way around.

* Due to Fervor and Battle Trance, Troll Warlord is one of the best heroes to deal with Supernova.

* Spiked Carapace reacts on any of the damage over time from Phoenix's abilities and can interrupt Sun Ray and Icarus Dive.

* Whirling Axes (Melee) makes it hard to land a Coup De Grace.
* Troll Warlord often buys Silver Edge and Monkey King Bar, the items that greatly help against Phantom Assassin's Blur ability.
* Battle Trance completely negates Phantom Assassin's large damage output, preventing Troll Warlord from dying easily. The lifesteal also allows Troll Warlord to restore much of his health.
Additional:
* Troll Warlord can build a Silver Edge or a Monkey King Bar to completely ignore Blur.
* Whirling Axes (Melee) provides a 60% miss chance, making a Coup de Grace critical strike very hard to land.
* Battle Trance negates Coup de Grace, preventing Troll Warlord from dying to her critical hits.

* Heroes with heavy early and mid-game magical damage are also problematic for Phantom Assassin due to being able to easily kill her before she gains an item advantage: Lina, Necrophos, Nyx Assassin, Gyrocopter. Should be noted these heroes are usually quite squishy and don't scale well with health. So to some respect, they are on a time crunch.

* Mobility heroes will often be rooted by Troll Warlord and unable to escape, like Storm Spirit.

* Mana Burn is capable of removing most of Storm Spirit's large mana pool, along with dealing heavy damage and quickly depleting his chances of escaping a gank or fight.
Additional:
* Mana Burn removes much-needed mana for Ball Lightning.
* Spiked Carapace triggers on Static Remnant for an easy stun.

* Nyx Assassin can reflect Life Break with Spiked Carapace.

* Carries that can out damage Huskar will do well against him: Legion Commander, Faceless Void, Troll Warlord, Phantom Assassin.

Additional:
* Whirling Axes (Melee) provides a 60% miss chance, resulting in Huskar's attacks missing a lot of the time if it isn't dispelled.
* Troll Warlord's Fervor ramps up in a very similar way as Huskar's Berserker's Blood: as soon as Huskar has high enough health regeneration, Troll Warlord has a high enough attack speed to negate it.

* A good Nyx can reflect Queen of Pain's Sonic Wave with his Spiked Carapace, or even initiate a gank on her in Vendetta while she farms a creep wave with Scream of Pain.
* Her strength to intelligence ratio is bad enough that he should be able to kill her without even requiring a Dagon, provided he can get his full combo off.

* Nyx can walk into Firefly with Spiked Carapace and stun Batrider if he has no Spell Immunity, even if Batrider is focusing on other enemy hero.

* The huge physical damage taken from Vendetta will force Necrophos to use Ghost Shroud, which is good for a followup with Dagon and Ethereal Blade, both of which are common items on Nyx Assassin.
* Using Ghost Shroud also sets Necrophos up for a Mana Burn or Impale.

* With her passive Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious Stone Gaze.
* Mana Burn quickly destroys Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Additional:
* Level 4 Mana Burn burns of Medusa's mana every 5 seconds if Medusa only increases her mana pool with intelligence. Additionally, 70% of the Mana Burn damage gets mitigated by Mana Shield, burning even more mana.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.

* Spiked Carapace stops Snapfire's Mortimer Kisses.

* Mana Burn does tons of damage against Lina because of her high intelligence. The mana burn also prevents Lina from casting her full combo.
* Spiked Carapace can easily be used to counter Lina's abilities because of their long cast animation, and could probably kill Lina outright if Laguna Blade is reflected.

* Nyx Assassin can take advantage of every one of Puck's weaknesses. His entire skill set is very effective in countering Puck.
* Because Illusory Orb is such a slow moving projectile, Nyx Assassin can simply walk into the orb and activate Spiked Carapace, stunning Puck and setting up an easy Impale. This can be circumvented by using Phase Shift while the orb is traveling, however, that means that Puck cannot use Phase Shift to dodge any other skill nor use it to safely blink away from a fight.
* Puck is an intelligence hero that likes to build intelligence items such as Eul's Scepter of Divinity, Scythe of Vyse, and Dagon. This makes Mana Burn that much more deadly against Puck.
* An ill-timed Phase Shift can turn into an easy setup for Impale.
Additional:
* Illusory Orb is easy to reflect with Spiked Carapace, either stunning Puck and setting up an easy Impale or forcing a premature Phase Shift.
* Puck is an intelligence hero that tends to build intelligence items, making it vulnerable to Mana Burn.
* An ill-timed Phase Shift can easily set Puck up to be stunned by Impale.
* Puck's low base armor and below average agility gain mean it is always susceptible to Vendetta.

* Nyx's Spiked Carapace can reflect the damage of Sharpshooter, instantly killing hoodwink. Nyx can also use Vendetta to position himself in such a way to screen allies from Sharpshooter and catch Hoodwink by surprise.

* Nyx Assassin takes advantage of Invoker's massive intelligence gain and mana pool to do tons of damage using Mana Burn, as the spell does more damage based on the target's intelligence.
* Nyx Assassin can simply activate Spiked Carapace while under many Invoker's abilities to stun him.

* Spiked Carapace can be easily triggered by Flame Guard or Battle Fury, setting up a deadly Impale.
Additional:
* With Vendetta, Nyx Assassin can move closely to Ember Spirit when he's farming with his Flame Guard and use Spiked Carapace with Impale to provide a reliable and long disable.
* Mana Burn is also good, as Ember Spirit relies on his limited mana pool for the early to midgame.

* Battle Trance should make Primal Beast very careful about how hard he wants to commit with Onslaught, with the root making him unable to cast it or use Trample to its fullest.

* Spiked Carapace allows Nyx to get an easy long-duration stun on Weaver once he uses Shukuchi, and then he can follow up with Impale.
* Vendetta works as a great setup for both Impale and Spiked Carapace and can deal decent damage to Weaver. Additionally he can neutralize The Swarm beetles due to his invisibility duration.

* Impale and Spiked Carapace interrupts Upheaval with ease.
* Warlock's low health pool, mobility, and high intelligence gain makes him a prime target for Nyx Assassin's burst damage.

* Mana Burn drains Pudge's little mana which may render Meat Hook and Dismember unusable.
* Impale and Spiked Carapace can be used to cancel Dismember easily, and can even do so when Pudge uses it on Nyx Assassin, if timed correctly.

* Whirling Axes (Melee)'s blind makes Sven nearly useless in the early game and allows Troll Warlord to take him on comfortably.
* Battle Trance will mean Sven will never take Troll out in a 1vs1 with equal farm.
Additional:
* Berserker's Rage together with Troll Warlord's high attack speed gives Troll a high chance of rooting enemies, which allows Troll Warlord to man-fight Sven.
* Whirling Axes (Melee) provides a 60% miss chance, and the passive armor provided by Berserker's Rage makes Troll resilient to physical damage in early game. Sven's God's Strength is much less effective as a result.
* Beware that Sven can farm much faster than Troll Warlord by stacking ancients and clearing them with Great Cleave.

* Spiked Carapace can stop Dawnbreaker's Solar Guardian which will eliminate her global presence and limits her movement around the map.

* Vendetta disables Vengeance Aura and allows him to attack Vengeful Spirit with Impale and Mana Burn.
* Spiked Carapace is easy to use against a Wave of Terror or Magic Missile.

* Nyx Assassin's Spiked Carapace will stun Leshrac when hit by any of his AOE abilities.
* Mana Burn deals high damage due to Leshrac's high intelligence gain and burns a large amount of Leshrac's essential mana pool.

* Due to Fervor and Battle Trance, Troll Warlord has a significant attack speed, enabling him to crush Tombstone quickly.
* Undying usually stays at the front line with no disables, making him an easy target for Troll Warlord.

* Nyx Assassin has a lot of burst damage from his Impale, Mana Burn, Dagon, and the bonus damage from Vendetta. All of this damage is enough to kill Drow Ranger.
* Nyx Assassin is usually invisible most of the time thanks to his ability Vendetta, which allows him to gank Drow Ranger easily.

* Mana Burn can instantly deplete Tidehunter's low mana pool, especially in the early game, potentially preventing Tidehunter from casting Ravage.
* Ravage's travel time allows Nyx Assassin to easily stun Tidehunter with Spiked Carapace.

* His whole skillset acts like a counter to Tinker:
* Impale prevents Tinker from blinding Nyx Assassin or fighting back, while giving Nyx' allies time to catch up to Tinker's position.
* Mana Burn generally deals more damage to intelligence based heroes like Tinker
* Spiked Carapace can stun Tinker at a moment of Nyx Assassin's choosing if March of the Machines has been cast. It is also quite easy to time Spiked Carapace against Heat Seeking Missiles.
* Vendetta allows Nyx to approach Tinker in the trees or wait for him in common hiding spots and deal heavy damage to his low armor.
Additional:
* March of the Machines and Heat-Seeking Missile allow easy Spiked Carapace stuns.
* As a fragile hero that relies on mana and intelligence items, Tinker is vulnerable to Mana Burn.
* Nyx Assassin's stuns can interrupt Rearm and leave Tinker helpless.

* Silencer is rather squishy and has poor mobility without items, making him an easy target for Nyx.
* Silencer's intelligence steal ability is a complete disadvantage against Nyx Assassin as Mana Burn will deal increasing damage for each point of intelligence Silencer has stolen, turning Silencer's intelligence steal against him.

* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin

* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom

Additional:
* Spiked Carapace can be used to reflect Illuminate damage and stun Keeper of the Light.
* Vendetta allows Nyx Assassin to follow Keeper of the Light around if he tries to split-push.
* Keeper of the Light is very squishy and will very quickly die to Vendetta and it's followup abilities.
* However, Mana Burn's Mana Burn can be more or less mitigated with Chakra Magic.

* Heroes that rely on right-clicks will find that their attacks will miss a lot, due to Whirling Axes (Melee)'s miss chance. Such heroes include Phantom Assassin, Terrorblade, and Morphling.

* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom

* Heroes with high burst damage: Lina, Lion, Luna, Nyx Assassin, Queen of Pain.

* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* Any hero who can survive Magnus's initiations and manfight him: Huskar, Faceless Void, Weaver, Abaddon, Troll Warlord, Alchemist, Dragon Knight, Night Stalker, Viper.

* Heroes that can pick you off: Clinkz, Nyx Assassin, Puck, Riki.

* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom

* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom

Additional:
* Skywrath Mage's low health makes him rather easy prey for Nyx Assassin and his lack of armor generally means he'll take the full brunt of a Vendetta strike.
* Mana Burn is annoying at all stages of the game as it turns Skywrath Mage's high intelligence growth against him.
* Spiked Carapace gives Nyx some degree of protection against Skywrath's spells.

* Heroes with damage burst can often kill Chen or his allies before he can use Hand of God: Lina, Techies, Shadow Fiend, Pugna, Nyx Assassin.

* Crystal Maiden has a very bad movement speed, so Impale is easy to land against her. Furthermore, even while trapped by Frostbite, Nyx Assassin can still cast Impale.
* Crystal Maiden has very low armor, so Vendetta is very effective.
* Nyx Assassin has two ways to stop Freezing Field, provided she doesn't get a Black King Bar. He can pop Spiked Carapace and simply walk into the field, or he can use Impale to interrupt the field, since Crystal Maiden has to channel it.
Additional:
* Spike Carapace easily interrupts Freezing Field.
* Frostbite's damage over time sets up an easy Spiked Carapace stun.
* Crystal Maiden is extremely fragile and dies quickly to Nyx Assassin's burst damage.

* Heroes with a low attack speed or are fragile will find themselves unable to deal with Troll Warlord's high physical damage and attack speed, like Crystal Maiden or Sven.

* Troll Warlord can root and deal a lot of damage to a single Meepo while lifestealing through the assault from the other Meepos. Meepo needs expensive items like Ethereal Blade or Heaven's Halberd to be able to fight him.

* Enigma is fragile, and lacks escapes, being dependent on Blink Dagger for mobility. Ganking Heroes or Heroes with burst damage will likely kill him before he can do anything. Such Heroes include: Lina, Lion, Luna, Puck, Slark, Nyx Assassin, etc.

Additional:
* Enigma's uncontrollable damage from Malefice and Midnight Pulse make him easy to stun with Spiked Carapace.
* Black Hole can be easily interrupted by Impale or Spiked Carapace.

* Vendetta allows Nyx to sneak up on Lion and deal massive damage to him, especially when followed up with an Impale, Mana Burn, or even Dagon.
* Spiked Carapace has the potential to not only nullify Lion's damage, but also cripple and potentially deal massive damage to Lion, especially if he reflects Finger of Death.

* Many of Nyx Assassin's abilities are good against Windranger.
* Impale is great for stunning Windranger and allowing additional disables to be landed.
* Mana Burn is useful against Windranger's decent intelligence growth and also burns some mana, preventing her from using more abilities.
* Spiked Carapace is easy to use against Powershot.
* Vendetta allows Nyx Assassin to sneak up on and deal massive damage to Windranger without giving Windranger a chance to use Windrun to evade it.
* Nyx Assassin's item build allows him to easily deal with Windranger.

* Berserker's Rage will repeatedly trap Bloodseeker in a one-on-one fight.
* Whirling Axes (Melee) blinds Bloodseeker, causing him to miss 60% of the time, and therefore reduces his ability to gain the upper hand in teamfights.

* Generally speaking, Spectre is a strong teamfighter but a weak manfighter. She has no tool to deal with troll warlord once he has his sight locked on her.
* Troll often buys Silver Edge and Monkey King Bar, which greatly countered Spectre's passive and item build (Silver Edge can disable passive while providing some damage, Monkey King Bar provides accuracy to counter Radiance and Butterfly miss chance).
* Black King Bar allows troll to bypass the damage return from Blade mail should Spectre attempts to fight back Troll. However, Black King Bar is generally not very effective against Spectre as her skills can pierce the spell immunity. Still, it offers protection against Blade mail, a common item for Spectre in the mid game.
* Troll has high lifesteal from Battle Trance and Satanic, which help him survive the damage from Desolate should the break duration is over.
* Battle Trance and Fervor mean Spectre will have a hard time fighting troll and cannot take him down, even with equal farm.

* Assassinate is easy to reflect with Spiked Carapace for massive damage.
* Shrapnel's area damage can set up an easy stun with Spiked Carapace, especially when combined with Vendetta.
* In the early game, Sniper's low health pool and high intelligence makes him easy prey for Nyx Assassin.

* Outworld Destroyer's high mana pool, high intelligence, and makes him a prime target for Mana Burn.
* If timed correctly, Spiked Carapace will return the full damage from Sanity's Eclipse back to Outworld Destroyer. Even a reflected Arcane Orb can deal significant damage and make him vulnerable to a follow-up from Nyx Assassin.
* Spiked Carapace is also the perfect tool against Astral Imprisonment: if used on Nyx, he can reflect the damage back as he comes out of the prison by casting the ability while imprisoned.
Additional:
* Outworld Destroyer's high intelligence gain and fragility makes him an easy target for a massive Mana Burn, as well as killing him outwards with Nyx Assassin's high burst damage.
* Astral Imprisonment can be easily exploited by Nyx Assassin with his abilities. As long as Astral Imprisonment was not cast on Nyx Assassin, it will make an opportunity for an easy stun, either by Spiked Carapace (if Outworld Destroyer hid his allies or your allies) or Impale (if he hid himself). If Astral Imprisonment was cast on Nyx Assassin, using Spiked Carapace while banished will proc the stun after the disable, since Spike Carapace has a 0 second cast time and Astral Imprisonment deals damage right after the disable ends.
* An ill-timed Sanity's Eclipse or well timed Spiked Carapace can deal a lot of damage to Outworld Destroyer and stun him, unless Outworld Destroyer used Black King Bar beforehand.

* Whirling Axes (Melee) provides a 60% miss chance, which can make the attack speed bonus from Hunter in the Night largely ineffective.
* Berserker's Rage together with Battle Trance and Fervor stacks gives him a high chance of rooting Night Stalker, which allows Troll Warlord to man-fight Night Stalker in any stage of the game, regardless of whether or not it's night.
* Night Stalker is not a common Monkey King Bar carrier to counteract this problem.

* Troll Warlord's passive root, high attack speed, and blind from Whirling Axes makes him an exceedingly difficult opponent for Anti-Mage to take down in a one-on-one fight.
* Troll Warlord's low mana causes him to take little damage from Mana Void.
Additional:
* Whirling Axes (Melee) provides a 60% miss chance, preventing Anti-Mage from burning Troll Warlord's small mana pool.
* Troll Warlord's passive root allows him to very effectively fight an Anti-Mage by preventing Anti-Mage from Blinking away. This is even more effective when combined with a Skull Basher or Abyssal Blade.
* Counterspell will do nothing to prevent Troll Warlord's high physical damage.
* Due to Troll Warlord's abysmal base intelligence and intelligence gain, he is one of the worst targets to use Mana Void on.

* Due to Pugna's incredible intelligence growth and terrible strength growth, Nyx should always be able to take you out with his combo, with or without an added Dagon. Mana Burn will deal a large amount of damage in particular, especially in the late game.
* Spiked Carapace is also a great tool versus Pugna. A good player will wait for you in Vendetta until you farm a creep wave with Nether Blast and reflect it back at you as their initiation and setup for Impale.
Additional:
* Nether Blast's animation makes it easy to time Spiked Carapace for a stun.
* Pugna has the largest intelligence gain in the game, making him a prime target for Mana Burn.
* Pugna needs to channel Life Drain, making him easy to hit with Impale.

* Nyx Assassin's high burst damage can be the bane of Dark Willow, as her low health makes it difficult to survive long enough to escape through Shadow Realm.
* Spiked Carapace can be triggered by walking deliberately into Bramble Maze, leaving Dark Willow stunned and defenseless.

* Troll Warlord's ability to attack as a ranged hero allows him to destroy Juggernaut's Healing Ward from afar.
* Battle Trance, when activated during Omnislash, allows Troll Warlord to survive the full duration of Omnislash and retaliate once it is over.

* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin