* Being mostly a physical damage dealer, Sniper's effectiveness is greatly reduced by Omniknight's Guardian Angel.
* Omniknight's Degen Aura allows him to slow sniper and catch him. Sniper has to then use some escape item.
* Omniknight can also protect an ally from being finished off by Assassinate by using Purification.

* Sniper is completely helpless against Incapacitating Bite, and can be seriously damaged by Spiderlings in lane.

* In team fights, Guardian Angel renders Drow Ranger's physical damage useless.

* Drow Ranger's lack of mobility makes her easy prey for Broodmother and her Spiderlings.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

Additional:
* Purification easily catches Phantom Assassin when she jumps in to attack.
* Guardian Angel renders Phantom Assassin useless, as she depends entirely on physical attacks.

* Phantom Assassin's single target abilities make her very helpless against swarms of spiderlings.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Aside from Spin Web, Incapacitating Bite can cripple her due to being reliant on physical attacks and critical strikes.
Additional:
* Phantom Assassin's single target abilities make her very helpless against swarms of Spiderlings.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Incapacitating Bite cripples her due to reliant on physical attacks.

* Heroes with plenty of summons, such as Broodmother or Nature's Prophet can have their minions soak up most of your Paralyzing Cask.

* Guardian Angel protects allies from Death Ward's physical damage.
* Purification and Heavenly Grace will most likely save teammates from dying to Maledict.

* Phantasms can be easily killed with Purification.
* Heavenly Grace dispels the stun from Chaos Bolt and the armor reduction from Reality Rift.
* Guardian Angel works well against Chaos Knight's overwhelming reliance on physical burst damage.
Additional:
* Purification heals a teammate targeted by Reality Rift and heavily damages Chaos Knight and his illusions in the process.
* Guardian Angel blocks all of Chaos Knight's damage for a duration.

* Illusion-based and multi-unit heroes can take advantage of Chaos Knight's lack of area damage: Naga Siren, Phantom Lancer, Meepo, Broodmother

* Heroes with illusions and summons can swarm Bane, who has no area abilities: Broodmother, Chaos Knight, Nature's Prophet, Phantom Lancer, Terrorblade

* Heroes with dispels can dispel Bane's disables from their allies: Oracle, Legion Commander, Omniknight

* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.

* Omniknight can dispel Hex or Shackles with Heavenly Grace. He can also heal teammates which you disabled. The same goes to Abaddon's Aphotic Shield .

* Webbed areas can be used to hit and run, covering distance hastily weakening her on the way and initiating ganks.
* Even though Medusa can hunt down Spiderlings easily when given enough range, after an Incapacitating Bite she will get her swarmed in no time.
* Medusa usual do not build a BKB to benefit from Mana Shield fully while Broodmother can fit a Diffusal Blade to burn away mana.
Additional:
* Incapacitating Bite will give Medusa a dire time to clear horde of small spiderlings or retaliate Broodmother herself.
* Spin Web will allow broodmother to pick her own fights and sometimes slip away to ambush Medusa.

* Broodmother can destroy Nature's Prophet's treants with Spawn Spiderlings and summon spiderlings in their place.
* Broodmother loves buying Orchid Malevolence, which can prevent Nature's Prophet from escaping with Sprout and Teleportation.
Additional:
* Sprout cannot protect Nature's Prophet if Broodmother puts down a web.
* Nature's Prophet's low mobility means he is defenseless against Incapacitating Bite.
* Spiderlings absorb much of the damage from Wrath of Nature.

* Global Guardian Angel will protect his allies from Spectre's Haunt, both when they are alone and in teamfights.
* Purification is a major problem for melee enemies, Spectre included, since they must be next to an enemy in order to attack. The AoE damage also allows Spectre to be singled out from her illusions.
* Degen Aura will prevent Spectre from chasing Omniknight, further exacerbated by her terrible mobility outside Haunt.

* Chen has no area-of-effect spells to deal with Broodmother's spiderlings and must rely on his creeps to take care of them.
* Spawn Spiderlings can kill Chen's creeps and spawn spiderlings in their place.
* Spin Web allows Broodmother to disrupt Chen's jungling.
* Incapacitating Bite and Insatiable Hunger let Broodmother easily win fights against Chen.
Additional:
* Chen's low mobility and lack of AoE abilities makes him an easy target for Broodmother and her Spiderlings.
* Broodmother can easily pick off Chen's creeps with Spawn Spiderlings, and by ambushing them through terrain in her web.

* Slark's dependence on Pounce and close range makes him very easy to hit with Purification.
* Slark's damage, even with a high count of Essence Shift, is easily negated by Omniknight's heals and Guardian Angel.

* Guardian Angel negates most of Gyrocopter's physical АоЕ damage.
* Heavenly Grace dispels Homing Missile stun.

* Exorcism's damage is blocked by Guardian Angel.
Additional:
* Degen Aura reduces Death Prophet's movement speed, keeping her in range.
* Guardian Angel nullifies the physical damage from Exorcism.

* Guardian Angel's near invulnerability denies Bloodseeker the bonuses from Thirst, preventing him from gaining the upper hand in teamfights.
* Purification's pure damage makes it hard for Bloodseeker to pursue enemies, and prevents him from replenishing his health by finishing off enemies.

* None of Arc Warden's skills work against Broodmother and her Spiderlings.
* Arc Warden is forced to go any lane other than mid, which he doesn't want to do, because on the lane against Broodmother he'll die over and over again.
* Broodmother is a hero best known for ending the game very early, and Arc Warden needs a couple of items to be effective.
* Arc Warden has no disables to stop Broodmother from lifestealing with Insatiable Hunger and shredding through Zet's low armor.

* Purification does great damage to Clockwerk when fighting an enemy inside Power Cogs.
* For the same reasons, Omniknight also makes a powerful ally for Clockwerk when the situation is reversed.

* Spiderlings melt away Living Armor almost instantly.
* The vision from Eyes In The Forest may prove dangerous for Broodmother, however.

* Heavenly Grace reduces Fireblast stun time and dispels Ignite.
* Purification can heal damaged hero if needed.

* Broodmother can easily clear Wraith King's skeletons with Spawn Spiderlings and summon spiderlings in their place.
* With Diffusal Blade, Broodmother can prevent Wraith King from reincarnating unless Wraith King has his Aghanim's Shard.

* Guardian Angel completely negates all physical damage, including Omnislash.
Additional:
* Omnislash is blocked by Guardian Angel.

* Riki takes a lot of damage from Purification while ganking Omniknight's allies or himself.
* Heavenly Grace instantly purges the slow from Diffusal Blade, while also providing a large amount of survivability for his victim.
* Degen Aura can hinder Riki's positioning tactics and put a heavy toll on Riki's already poor movement speed.
* Omniknight can easily save his allies by using Guardian Angel in combat.

* Any hero that can nullify effects of Chronosphere: (Omniknight, Keeper of the Light with Aghanim's Scepter during daytime, Winter Wyvern), banishing him or Faceless Void (Outworld Destroyer, Shadow Demon, Earth Spirit with Aghanim's Scepter) or protecting him in other ways (Dazzle, Oracle, Abaddon) can greatly limit Chronosphere's potential.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King.

* Heroes with summons: Lycan, Broodmother, Visage.

* Broodmother's Insatiable Hunger and Troll Warlord's Battle Trance can nullify Sunder.

* Heroes with summons like Broodmother,Enigma, Invoker, Nature's Prophet, Lycan, Visage;or illusions, like Naga Siren, Phantom Lancer, Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity mines in the early game.

* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.

* Omniknight with Heavenly Grace
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

Additional:
* Guardian Angel completely negates all of Lycan's damage since Lycan mainly deals physical damage.
* Purification can also be a problem for Lycan, as Purification deals damage around the target, which poses a problem for him and his summons.

* Heavenly Grace dispels the stun from Ink Swell, and greatly reduces Soulbind's duration.
* Purification can turn the tables on enemies trying to get close to stun with Ink Swell.

* Viper's lack of escape and durability means he can be ran over in a laning stage by Spiderlings.
* Broodmother can bring Viper down quickly with Insatiable Hunger activated.

* Chain Frost can bounce to the Spiderlings that Broodmother spawns.

* Purification allows Omniknight to keep a hero trapped in the Static Storm alive.

* In the early game, Omniknight can look like an easy target for Spirit Breaker, but with Purification and Degen Aura, what could be an opportunity could quickly turn into disaster.
* Heavenly Grace can be used to counter Charge of Darkness by minimizing the damage and lowering the stun duration with status resistance.
* Spirit Breaker's Greater Bash from all sources (Charge of Darkness or normal attacks) deals lesser damage if he is within the radius of Degen Aura.
* Due to this, Spirit Breaker's damage will always be lower when targeting Omniknight.

* Guardian Angel completely counters Winter's Curse if he is able to cast it.
Additional:
* Guardian Angel completely counters Winter's Curse, allowing his team to survive Winter Wyvern's initiation.
* Purification and Heavenly Grace are very useful against Arctic Burn and Splinter Blast as well.

* Guardian Angel makes allies immune to all physical damage, effectively causing Tidebringer to do no damage.
* Purification is a powerful, pure damaging heal that can save Omniknight's allies after Kunkka's large damage.

* Enchantress is well known for taking control of various summons with her Enchant. However, Broodmother's summons are not a good target for that, because she can swarm up a bunch of her summons with Spawn Spiderlings and Enchantress has no good waveclear (Spawn Spiderlings can also kill creeps controlled with Enchant).
Additional:
* Enchantress' lack of AoE abilities allows Broodmother to swarm her with Spiderlings.
* Spawn Spiderlings can kill enchanted creeps.

* The pure damage provided by Purification is a great addition for killing Ember Spirit, as well as a good way of saving teammates.
* Guardian Angel will temporarily save his allies from Sleight of Fist's physical damage, and Ember Spirit is not a hero that will get Orchid Malevolence to counter it.

* Spin Web and Broodmother's auto-attacks allow her to gank Rubick easily before Rubick has a chance to retaliate, especially if Broodmother obtains Orchid Malevolence.
* Broodmother loves buying Diffusal Blade, which drains Rubick's low supply of mana, preventing Rubick from spamming his abilities.
* Though Insatiable Hunger is a great spell to steal, Broodmother's untargetable nature and her low cooldown spells makes it a difficult spell to steal.

* Omniknight: An undispellable Heavenly Grace can easily save a victim of Shadow Demon.

* Heroes that can save their allies can be a big problem for Mars: Dazzle, Omniknight.

* Both Guardian Angel and Purification are perfect counters against Duel.
Additional:
* Purification prevents Legion Commander from killing her target, and will always hit her during Duels.
* Guardian Angel completely wastes Duel's duration, and can save an ally across the map when upgraded with Aghanim's Scepter.

* Omniknight's healing prevents allies from dropping low enough for Culling Blade. However, it can still go through all his buffs.
* Axe also enjoys getting close to allied heroes in order to damage them with his Counter Helix, which can easily be punished by Purification.

* Broodmother relies less on abilities and more on right-clicks.
* Spiderlings can overwhelm Silencer, who has mediocre armor and no escape tool.

* Her Spiderlings can harass Luna in lane heavily, as Luna has no AoE abilities to clear Spiderlings.
* Broodmother can knock down towers in the early game quickly, and limit Luna's farming space.

* Broodmother can kill Invoker easily in the early game with her Spawn Spiderlings and her spiderlings.
* Broodmother is both an Orchid Malevolence and a Nullifier carrier. As she can farm it early, she can kill Invoker easily.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

* Heroes with spell immunity or pseudo-blinks which provide invulnerability: Lifestealer, Juggernaut, Omniknight, Huskar , and Tusk have spells which allow them to easily escape Dream Coil.

* Heroes with illusions and summons can manfight Night Stalker: Terrorblade, Beastmaster, Broodmother.