* Sharpshooter breaks Blur and Coup de Grace especially with the level 25 talent.
* Because Phantom Assassin is often reliant on critical strikes, Hoodwink can have enough time to simply move near a tree and escape.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

Additional:
* Purification easily catches Phantom Assassin when she jumps in to attack.
* Guardian Angel renders Phantom Assassin useless, as she depends entirely on physical attacks.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

* Durable heros relied a lot on their main passive effects and items' effects such as Bristleback, Underlord and Dragon Knight can be removed their effects easily with Sharpshooter's break.

* Bristleback's passive Bristleback can be disabled by Hoodwink's Sharpshooter ability for a long period of time

* The pure damage provided by Purification is a great addition for killing Ember Spirit, as well as a good way of saving teammates.
* Guardian Angel will temporarily save his allies from Sleight of Fist's physical damage, and Ember Spirit is not a hero that will get Orchid Malevolence to counter it.

* Global Guardian Angel will protect his allies from Spectre's Haunt, both when they are alone and in teamfights.
* Purification is a major problem for melee enemies, Spectre included, since they must be next to an enemy in order to attack. The AoE damage also allows Spectre to be singled out from her illusions.
* Degen Aura will prevent Spectre from chasing Omniknight, further exacerbated by her terrible mobility outside Haunt.

* Guardian Angel protects allies from Death Ward's physical damage.
* Purification and Heavenly Grace will most likely save teammates from dying to Maledict.

* Heavenly Grace dispels the stun from Ink Swell, and greatly reduces Soulbind's duration.
* Purification can turn the tables on enemies trying to get close to stun with Ink Swell.

* Sharpshooter can kill easy when Morphling is going on full agility strategy (Only in early and mid game).
* Scurry can help to catch up Morphling when using Waveform or for escape.

* Slark's dependence on Pounce and close range makes him very easy to hit with Purification.
* Slark's damage, even with a high count of Essence Shift, is easily negated by Omniknight's heals and Guardian Angel.

* Guardian Angel negates most of Gyrocopter's physical АоЕ damage.
* Heavenly Grace dispels Homing Missile stun.

* Being mostly a physical damage dealer, Sniper's effectiveness is greatly reduced by Omniknight's Guardian Angel.
* Omniknight's Degen Aura allows him to slow sniper and catch him. Sniper has to then use some escape item.
* Omniknight can also protect an ally from being finished off by Assassinate by using Purification.

* Both Guardian Angel and Purification are perfect counters against Duel.
Additional:
* Purification prevents Legion Commander from killing her target, and will always hit her during Duels.
* Guardian Angel completely wastes Duel's duration, and can save an ally across the map when upgraded with Aghanim's Scepter.

* Acorn Shot combined with attack modifiers such as Maelstrom or Daedalus makes a quick work of Phantom Lancer's illusions.
* Bushwhack will stun Phantom Lancer and his illusions if they're near a tree.
Additional:
* Bushwhack will stun and make a quick work of Phantom Lancer and his illusion when he's near a tree.
* Sharpshooter breaks Juxtapose and deals hefty damage.

* Omniknight's healing prevents allies from dropping low enough for Culling Blade. However, it can still go through all his buffs.
* Axe also enjoys getting close to allied heroes in order to damage them with his Counter Helix, which can easily be punished by Purification.

* Huskar’s low health play style put him at extreme risk to Sharpshooter's extreme damage. In addition, it breaks Berserker's Blood, nullifying Huskar's power source.

* In team fights, Guardian Angel renders Drow Ranger's physical damage useless.

* Exorcism's damage is blocked by Guardian Angel.
Additional:
* Degen Aura reduces Death Prophet's movement speed, keeping her in range.
* Guardian Angel nullifies the physical damage from Exorcism.

* In the early game, Omniknight can look like an easy target for Spirit Breaker, but with Purification and Degen Aura, what could be an opportunity could quickly turn into disaster.
* Heavenly Grace can be used to counter Charge of Darkness by minimizing the damage and lowering the stun duration with status resistance.
* Spirit Breaker's Greater Bash from all sources (Charge of Darkness or normal attacks) deals lesser damage if he is within the radius of Degen Aura.
* Due to this, Spirit Breaker's damage will always be lower when targeting Omniknight.

* Guardian Angel's near invulnerability denies Bloodseeker the bonuses from Thirst, preventing him from gaining the upper hand in teamfights.
* Purification's pure damage makes it hard for Bloodseeker to pursue enemies, and prevents him from replenishing his health by finishing off enemies.

* Purification does great damage to Clockwerk when fighting an enemy inside Power Cogs.
* For the same reasons, Omniknight also makes a powerful ally for Clockwerk when the situation is reversed.

* Guardian Angel completely counters Winter's Curse if he is able to cast it.
Additional:
* Guardian Angel completely counters Winter's Curse, allowing his team to survive Winter Wyvern's initiation.
* Purification and Heavenly Grace are very useful against Arctic Burn and Splinter Blast as well.

* Phantasms can be easily killed with Purification.
* Heavenly Grace dispels the stun from Chaos Bolt and the armor reduction from Reality Rift.
* Guardian Angel works well against Chaos Knight's overwhelming reliance on physical burst damage.
Additional:
* Purification heals a teammate targeted by Reality Rift and heavily damages Chaos Knight and his illusions in the process.
* Guardian Angel blocks all of Chaos Knight's damage for a duration.

* Heavenly Grace reduces Fireblast stun time and dispels Ignite.
* Purification can heal damaged hero if needed.

* Guardian Angel completely negates all physical damage, including Omnislash.
Additional:
* Omnislash is blocked by Guardian Angel.

* Riki takes a lot of damage from Purification while ganking Omniknight's allies or himself.
* Heavenly Grace instantly purges the slow from Diffusal Blade, while also providing a large amount of survivability for his victim.
* Degen Aura can hinder Riki's positioning tactics and put a heavy toll on Riki's already poor movement speed.
* Omniknight can easily save his allies by using Guardian Angel in combat.

* Any hero that can nullify effects of Chronosphere: (Omniknight, Keeper of the Light with Aghanim's Scepter during daytime, Winter Wyvern), banishing him or Faceless Void (Outworld Destroyer, Shadow Demon, Earth Spirit with Aghanim's Scepter) or protecting him in other ways (Dazzle, Oracle, Abaddon) can greatly limit Chronosphere's potential.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King.

* Heroes who possess abilities that can save targets from being killed by Reaper's Scythe: Abaddon, Bane, Outworld Destroyer, Shadow Demon, Omniknight, etc.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

* Heroes with dispels can dispel Bane's disables from their allies: Oracle, Legion Commander, Omniknight

* Heroes with spell immunity or pseudo-blinks which provide invulnerability: Lifestealer, Juggernaut, Omniknight, Huskar , and Tusk have spells which allow them to easily escape Dream Coil.

* Omniknight can dispel Hex or Shackles with Heavenly Grace. He can also heal teammates which you disabled. The same goes to Abaddon's Aphotic Shield .

* Omniknight with Heavenly Grace
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Durable heros relied a lot on their main passive effects and items' effects such as Bristleback, Underlord and Dragon Knight can be removed their effects easily with Sharpshooter's break.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

Additional:
* Guardian Angel completely negates all of Lycan's damage since Lycan mainly deals physical damage.
* Purification can also be a problem for Lycan, as Purification deals damage around the target, which poses a problem for him and his summons.

* Guardian Angel makes allies immune to all physical damage, effectively causing Tidebringer to do no damage.
* Purification is a powerful, pure damaging heal that can save Omniknight's allies after Kunkka's large damage.

* Hex and Earth Spike do not cancel Hoodwink's ultimate, making those two abilities ineffective against her.

* Purification can heal allies while dealing pure damage to Sven.
* Heavenly Grace can remove Storm Hammer's debuff immediately or make it a very mediocre stun.
* Guardian Angel negate's Sven's massive damage during God's Strength.

* Omniknight: An undispellable Heavenly Grace can easily save a victim of Shadow Demon.

* Heroes that can save their allies can be a big problem for Mars: Dazzle, Omniknight.

* Monkey King often hides in trees, where he can be easily caught with Bushwhack.
* Acorn Shot can target enemies in the fog, including Monkey King when he is on a tree.
* Sharpshooter provides flying vision along the cast indicator while charging, which can be used to scout the trees for Monkey King.