* Arcane Orb deals pure damage, which ignores armor granted from permanent agility stacks.
* Astral Imprisonment can disrupt any Pounce attempt by banishing the leashed ally.
* Slark's low intelligence and therefore mana pool makes him more susceptible to Sanity's Eclipse.

* Thunder Strike provides vision on him while Slark is invisible.
* Glimpse's range at lvl 3-4 is more than enough to pull him back to a favorable position for your team to group up and kill him.
* Even though he is capable of picking you off and deal enough damage to kill you, Slark will be literally sticking his neck out, since jumping on Disruptor means being on his battleground.
* AoE silence and the ability to mute Black King Bar is deadly to Slark at all stages of the game.
Additional:
* Static Storm and Kinetic Field locks down Slark, as he cannot use Dark Pact to dispel any disables, or Pounce out while silenced.
* Glimpse puts an end to any attempts at ganking Disruptor or his allies, and also negates Slark's mobility by bringing him back into the fight if he tries to escape with Pounce.

* Arcane Orb's pure damage goes through Counterspell, and deals splash damage to illusions spawned from Manta Style.
* Sanity's Eclipse hits Anti-Mage while he is disabled with Astral Imprisonment, and forces him to take heavy damage due to his low intelligence.
* Equilibrium keeps Outworld Destroyer at high mana, thus greatly reducing the damage from Mana Void.
Additional:
* Counterspell doesn't work versus Arcane Orb because it does pure damage.
* Anti-Mage cannot burn all of Outworld Devourer's mana without disables due to Essence Flux.
* Anti-Mage's Manta Style illusions are quickly destroyed by Arcane Orb.
* However, if the enemy has multiple means of removing mana, Mana Void becomes a threat to Outworld Devourer, Anti-Mage has better mobility than Outworld Devourer with Blink, and Counterspell blocks a large portion of the damage from Sanity's Eclipse.

* Glimpse brings Anti-Mage back after he Blinks away.
* Static Storm stops Anti-Mage from Blinking.
Additional:
* Similar to Queen of Pain, Glimpse can disable Blink, negating his mobility.
* However, Counterspell can negate a majority of Disruptor's damage, which may require him to have a partner to successfully kill Anti-Mage.

* Thunder Strike can be used to cancel Earthshaker's Blink Dagger.
* Glimpse brings Earthshaker back after he jumps on Aghanim's Scepter upgraded Enchant Totem.
* Static Storm if used on a fight can prevent Earthshaker from executing his combo after blinking in.

* Outworld Destroyer's pure and magical damage is particularly effective against Earthshaker.
* Astral Imprisonment catches Earthshaker while he blinks in, preventing him from executing his combo.
* Earthshaker has mana troubles, and Outworld Destroyer's abilities can press this by stealing intelligence comes from Arcane Orb, therefore depleting his mana pool and mana regeneration.
* Sanity's Eclipse deals high damage to Earthshaker, due to his low intelligence and mana pool.

* Glimpse will return Underlord or any of his teammates attempting to escape with Dark Rift if timed correctly.
* Underlord is a slow and low mobility hero, easy to set up Static Storm and Kinetic Field, preventing him from using his abilities as well as preventing him using Dark Rift to escape

* Arcane Orb 's pure damage can do great damage to Underlord.
* Sanity's Eclipse can tear down Underlord's health by a large amount, since his mana pool is very low compare to OD's high mana pool.

* Heroes with mana burn: Nyx Assassin, Invoker, Outworld Destroyer, Pugna

* At around the 10-minute mark, Disruptor would normally be level 6 or 7. This means you can have a level 3/4 glimpse along with Static Storm. A high level glimpse is enough to pull Storm back to a Static Storm even after he used Ball Lightning due to his limited mana pool at that time.
* Be careful in the late game however, as there is a good chance he will kill you straight-out before Glimpse has finished bringing him back. Therefore Glimpse would simply bring him back to safety after he's murdered you or a teammate. Of course, this is assuming he hasn't silenced you with an item.

* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Ursa struggles against heroes with strong (and especially undispellable) disables (Disruptor, Puck, Shadow Demon, Outworld Destroyer and etc).

* Ursa struggles against heroes with strong (and especially undispellable) disables (Disruptor, Puck, Shadow Demon, Outworld Destroyer and etc).

* Sanity's Eclipse only triggers Bristleback's passive once, and deals high damage against Bristleback's low intelligence.

* Disruptor can disable Magnus's Blink Dagger using Thunder Strike during a considerable duration, disrupting his initiation attempts.
* Glimpse brings Magnus back after he escapes with Skewer and/or Force Staff.
* Static Storm if used on a fight can prevent Magnus from using Reverse Polarity after he jumps in.

* Arcane Orb deals pure damage against the real Terrorblade, bypassing his high base armor.
* Arcane Orb and Sanity's Eclipse will make very short work of Terrorblade and his illusions.

* Glimpse and Kinetic Field allows Disruptor to set up some early kills onto Shadow Fiend.
* Static Storm can be used to cancel the cast of Requiem of Souls.

* Arcane Orb deals pure damage, effectively bypassing Morphling's high armor from Attribute Shift (Agility Gain).
* Sanity's Eclipse is more effective against a low health and mana pool Morphling, enabling Outworld Destroyer to burst Morphling down before he can shift to Strength.
Additional:
* Arcane Orb deals high damage regardless of Morphling's high armor from Attribute Shift (Agility Gain).
* Because of Morphling's very low intelligence gain and base intelligence, Sanity's Eclipse will almost always be effective against Morphling.

* Glimpse directly negates Relocate.
Additional:
* Disruptor can always Glimpse back Io or his target after he Relocated nearby.
* Even better, thanks to the indicator on the ground, you can even preemptively drop Static Storm and Kinetic Field on the spot they will relocate to.
* Thunder Strike and Glimpse are also good tools to bring back an Io that Tethered away in the fog of war.

* Arcane Orb's pure damage ignores Mars' Bulwark.
* Astral Imprisonment can be used to stop Mars from being disruptive or save allies from his abilities.
* Sanity's Eclipse deals high damage to Mars, due to his low intelligence.

* Arcane Orb and Sanity's Eclipse quickly drains Pudge's limited mana pool, making him unable to use Meat Hook or Dismember and also bypasses Flesh Heap.
* Outworld Destroyer can save allies or himself caught by Dismember or Meat Hook with Astral Imprisonment.

* Blink and positioning is crucial for Queen of Pain. These factors are heavily countered by a good Glimpse.
* Static Storm is devastating for Queen as she relies heavily on her spells to inflict heavy burst damage.
Additional:
* Thunder Strike gives vision of Queen of Pain when she's trying to escape. When combined with Glimpse, her mobility and hit-and-run style can be negated.
* While in a team fight, Static Storm forces Queen of Pain to only use right-clicks.
* When combined with the Kinetic Field, she can only wait until she respawns.

* Astral Imprisonment is a versatile nuisance:
* If it is cast on a low-enough-health unit at least 1 second into Shallow Grave's duration, the Shallow Grave will end during the imprisonment, and the target will take lethal damage when released.
* It can be used remove Dazzle from the fight at a time he could have saved someone.
* It lets himself or an ally dodge all of Poison Touch's effects, for long enough to recover their Blink Dagger.

* Outworld Destroyer's pure and magical damage is particularly effective against Axe.
* Astral Imprisonment is an excellent way to defend against an initiating Axe.
* Sanity's Eclipse deals high damage to Axe due to his low mana pool.
Additional:
* Berserker's Call bonus armor doesn't block Arcane Orb's pure damage.
* Astral Imprisonment can be used to prevent an ally or Outworld Devourer himself from an Axe initiation.
* Axe's low mana means he's susceptible to a powerful Sanity's Eclipse.

* Kinetic Field and Glimpse can completely negate Stampede.

* Outworld Destroyer's pure damage from Arcane Orb is very effective at killing Troll Warlord quickly.
* Astral Imprisonment removes Troll Warlord from a fight for four seconds, minimizing his contribution to a teamfight, and potentially wasting over half of Battle Trance's duration.
* Troll Warlord gains a measly 1 intelligence point per level, meaning Sanity's Eclipse is especially effective, often instantly killing him.

* Arcane Orb deals constant pure damage, which bypasses Timbersaw's Reactive Armor.
* Sanity's Eclipse can hit targets inside Astral Imprisonment, which helps Outworld Destroyer finish off Timbersaw before he escapes with Timber Chain. It can also drain his mana, limiting his ability to escape should he survive.
Additional:
* Arcane Orb's pure damage ignores Timbersaw's Reactive Armor.
* Astral Imprisonment, if timed correctly, can interrupt Timber Chain, preventing him from escaping.

* Astral Imprisonment protects an ally for much of Rolling Thunder's duration, especially at the lower levels. As Rolling Thunder has a considerable cast animation, an Outworld Destroyer with Blink Dagger can initiate on him and destroy his timing.

* Astral Imprisonment can be used to protect allies by imprisoning either them or Spirit Breaker.
* Arcane Orb will heavily drain Spirit Breaker's intelligence, rendering him almost useless and unable to cast spells. Spirit Breaker's low intelligence also means Sanity's Eclipse will deal a lot of damage to him.

* Arcane Orb deals heavy damage to both Lone Druid and the Spirit Bear.
* Astral Imprisonment can prevent the Spirit Bear from attacking, which is Lone Druid's main damage output.
* Sanity's Eclipse deals heavy damage to Lone Druid.

* Arcane Orb's constant pure damage output is devastating to Dragon Knight.
* Dragon Knight's relatively low mana pool leads to heavy damage from Sanity's Eclipse, which also bypasses his armor.

* Glimpse moves Clockwerk away from allies struck by Hookshot, or under attack by Battery Assault.
* Static Storm can turn Power Cogs into Clockwerk's own grave, but Blade Mail will also return the damage to Disruptor.

* Outworld Devourer's pure damage from Arcane Orb can go through Cold Embrace.
* Outworld Devourer can negate the healing from Cold Embrace using Astral Imprisonment, and steal mana while doing so.
* Outworld Devourer's damage during Winter's Curse is reduced due to Arcane Orb being unable to target allies.
Additional:
* Winter Wyvern must never put her allies in Cold Embrace against Outworld Destroyer as Arcane Orb will continue to steal Intelligence and deal damage to the defenseless hero.
* Arcane Orb does not hit his allies when he is taunted by Winter's Curse, making it weak against allies, but strong versus enemies.
* Astral Imprisonment can protect a target inflicted with Winter's Curse.

* In the mid-game, Tidehunter relies on Kraken Shell to stay alive and get his Ravage off. Apart from Thunder Strike, none of Disruptor's abilities can be dispelled, so it's rather easy to trap him inside Kinetic Field and Static Storm.
* Be mindful, however, that Kraken Shell still makes Tidehunter very tanky, so be sure that you can kill him with your combo or your partners while he is silenced and trapped.

* Sanity's Eclipse does massive damage to Wraith King who naturally has a low mana pool and typically doesn't build items to increase it.
* Wraithfire Blast's slow projectile speed makes it easy to avoid using Astral Imprisonment.

* Thunder Strike provides vision of Monkey King when he's in the trees. The periodic damage will also keep Monkey King from using Tree Dance if he's on the ground.
* Glimpse pulls Monkey King out of the trees if he attempts to escape using Tree Dance, and can cause Wukong's Command to end prematurely if Monkey King is Glimpsed out of its radius.
* Kinetic Field and Static Storm can be used to hold Monkey King in place and ensure a kill.

* Outworld Destroyer doesn't care if Razor steals his damage because he does most of his damage through Arcane Orb.
* Astral Imprisonment can prevent Razor from using the stolen damage from Static Link or chasing with Eye of the Storm.
* Sanity's Eclipse will do a ton of damage to Razor due to his low mana pool.

* Tanky melee heroes that can easily be kited, which allows Outworld Devourer to deal heavy damage with Arcane Orb from a distance: Sven, Underlord, Bristleback.

* Any hero that can nullify effects of Chronosphere: (Omniknight, Keeper of the Light with Aghanim's Scepter during daytime, Winter Wyvern), banishing him or Faceless Void (Outworld Destroyer, Shadow Demon, Earth Spirit with Aghanim's Scepter) or protecting him in other ways (Dazzle, Oracle, Abaddon) can greatly limit Chronosphere's potential.

* Heroes with detection: Bounty Hunter, Disruptor, Razor, Slardar, Spectre, Spirit Breaker

* Disruptor can control where she goes with Kinetic Field and Glimpse. Static Storm shuts her down in teamfights.

* Shadow Demon, Outworld Destroyer and Tusk can all save a Lasso'd teammate with their defensive spells.

* Heroes who can hide the Dueled target (Outworld Destroyer, Shadow Demon, Tusk, Phoenix with Aghanim's Scepter etc).

Additional:
* Outworld Devourer can save an ally hero caught by Duel with Astral Imprisonment, and he can inflict heavy damage on Legion Commander with Arcane Orb to aid his ally. However, if he gets caught, he is unlikely to survive the duel, due to his lack of durability.

* Heroes that can negate Hoodwink's mobility: Kunkka, Disruptor, Mars.

* Heroes who possess abilities that can save targets from being killed by Reaper's Scythe: Abaddon, Bane, Outworld Destroyer, Shadow Demon, Omniknight, etc.

* Arcane Orb's pure damage penetrates Guardian Angel's defense.
* Outworld Destroyer's intelligence steal is also devastating to Omniknight's already low mana pool.

* Heroes with large magical AoE damage will fare well against Omniknight: Lich, Ancient Apparition, Jakiro, Disruptor

* As a spellcaster, silences will nullify him entirely. Some notable examples are Death Prophet, Drow Ranger, Bloodseeker, Disruptor and many others.
* Doom, as usual, fits this description nicely.

* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.

* Heroes with pure damage can kill Huskar when he inevitably gets low on health: Outworld Destroyer, Silencer.

Additional:
* Outworld Devourer can dodge Life Break with Astral Imprisonment, leaving him unharmed while Huskar loses HP.
* Sanity's Eclipse can deal massive damage to Huskar before he builds up his Berserker's Blood stacks due to Huskar's low mana pool.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Dark Seer relies on Surge for most of his mobility, so he's not very vulnerable to slows, but much more to root effects and walls or pseudo-walls such as Disruptor's Kinetic Field or Slark's Pounce.

* Astral Imprisonment can allow Outworld Destroyer to save himself or allies from Kunkka's full kit.
* Sanity's Eclipse deal a large amount of damage, as Kunkka's mana pool is much smaller than Outworld Destroyer's considering Kunkka is playing physical type.
* Arcane Orb deals pure damage, shredding through Kunkka and his team even with Ghostship's buff.

* The pure damage provided by Arcane Orb is a great addition for killing Ember Spirit.
* Astral Imprisonment fully negates all magic damage of Flame Guard and Searing Chains and will temporarily save himself from Sleight of Fist's physical damage, and Ember Spirit is not a hero that can counter these skills.

* Outworld Destroyer's pure damage will mop up Primal Split's units very quickly.

* Glimpse can return Tusk to where he was after using Snowball.

* Astral Imprisonment allows Outworld Destroyer to save himself or ally from Invoker's combo, or remove Invoker from a fight temporarily.
* Arcane Orb's pure damage will deal a lot of damage against Invoker's mediocre strength gain.
* EMP is useless against Outworld Destroyer by activating Equilibrium.
* However, be aware that Sanity's Eclipse will most likely not deal any damage at all, due to Invoker's high intelligence gain compared to Outworld Destroyer's.

* Sanity's Eclipse will likely instantly kill all illusions.

* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.

* Illusion based heroes (like Chaos Knight and Terrorblade) can't use their illusion beneficially against Sanity's Eclipse's high AoE burst damage.

* Riki and Disruptor: Smoke Screen and Static Storm can be thrown wherever Puck used Phase Shift, making Puck an easy target if it doesn't have Blink Dagger or is on cooldown. Puck is also very susceptible to Riki's high attack damage when attacking from the back. Glimpse also prevents Puck from escaping.

* Astral Imprisonment wastes Borrowed Time's duration.
* Outworld Destroyer's Sanity's Eclipse can kill Abaddon before Borrowed Time triggers.