* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Spectre more than most normal attacks, negating some of her tankiness.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Spectre.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom makes Spectre less disruptive. Combined with Aghanim's Scepter, it will disable Spectre passive skills, reducing her potential in teamfights.
Additional:
* Infernal Blade's damage is calculated by percentage of max health. Since Spectre is usually tanky, it will hurt her more than most normal attacks.
* Doom can entirely disable Spectre from a teamfight. If upgraded with Aghanim's Scepter, it will disable her passive skills which is she relies on, crippling her.

* Pudge's Dismember stops Spectre from escaping with Haunt.
* He can easily tank the damage reflected by Dispersion due to his high strength and the healing from Dismember.
* Should Spectre try to get away through the trees or over a cliff with Spectral Dagger, Pudge can hook her back.
* Spectre takes a long time to become powerful, and Pudge can ruin her early game with ganks.

* Tinker is heavily reliant on casting his spells and Doom can disable all of his abilities and items. An Aghanim's Scepter only makes it harder for Tinker to survive.
Additional:
* Tinker is heavily dependent on active abilities and Doom prevents him from using any of them.

* Meat Hook can be used to pull Tinker to Pudge while he is hiding in the trees, and a follow up with Dismember and Rot can lead to a valuable kill, as Tinker doesn't buy many survivability items.
* Flesh Heap makes it hard for Tinker to deal serious damage.
Additional:
* He can Meat Hook a Tinker hiding in the trees and follow it up with Dismember and Rot for an easy solo kill, as Tinker doesn't tend to buy survivability items.
* His innate magic resistance and huge health pool from Flesh Heap makes it hard for Tinker to deal serious damage to Pudge.

* Doom has several disable abilities to choose from jungle creeps (e.g. War Stomp, Ensnare) to deal with Shadow Fiend who lacks escape abilities.
* When Doom combines creep abilities with Scorched Earth, Infernal Blade, and Doom, Shadow Fiend most likely will die as he cannot use Shadowraze and Requiem of Souls to protect himself, and also cannot even flee by using Shadow Blade or Blink Dagger.
* Although Shadow Fiend has a high physical damage output, Doom has a large health pool to survive it, meaning Doom's combo with high magical damage output will shutdown Shadow Fiend first.
* Doom usually buys Radiance to improve his damage, making his nuke combo more deadly to Shadow Fiend. The blind also prevents Shadow Fiend from landing his attacks often.

* Heroes with channeling spells because Shadow Fiend has nothing to cancel channeling outside of Requiem of Souls: Bane, Enigma, Pudge, Shadow Shaman, Dawnbreaker, Warlock, Crystal Maiden.

* Heroes who recklessly jump on Pudge with their gap-closing abilities will be easy targets for Pudge's Meat Hook and Dismember Combo: Phantom Assassin, Faceless Void, Queen of Pain etc.

Additional:
* Meat Hook can pull an ally out of Chronosphere.
* Rot will keep damaging Void if he toggled it before Chronosphere, but you can lower your hp for Faceless Void.
* Flesh Heap will help Pudge survive through the Chronosphere with enough stacks, and follow with Dismember.

* Faceless Void relies on Time Walk for mobility and survivability but he can be prevented from utilizing it through Doom.
* Doom has a high cooldown duration for every ability except Infernal Blade, so he is not significantly affected by Time Dilation.

* Heroes with large health pools (Pudge) or good innate magic resistance (Anti-Mage) can be very problematic for Crystal Maiden, since even if they are under the effect of her ultimate for the entire duration, the damage output is simply not enough to kill or force them to retreat.

Additional:
* Meat Hook can cancel Freezing Field, even if Crystal Maiden has Glimmer Cape.
* She is also slow and fragile, making her a good target for ganking.

* Doom alone can easily pick off Crystal Maiden since she is fairly fragile, even with using only basic attacks, Infernal Blade, and Scorched Earth.
* Doom prevents her from using any abilities in a fight, making her impact negligible.
* Devour allows Doom to acquire a stun, allowing him to cancel Freezing Field without having to use Doom.

* Heroes who build a Black King Bar (or have any sources of spell immunity) to channel abilities/items can still get interrupted by Dismember: Enigma, Juggernaut, Phantom Assassin, Pugna, Elder Titan.

Additional:
* Even with Black King Bar, Pudge's Meat Hook and Dismember can still disable Engima while he is channeling Black Hole.
* Pudge's Aghanim's Shard upgraded Dismember and Meat Hook are great ways to save allies from Black Hole.
* Enigma is prone to ganks in the jungle or in the off-lane without proper vision. Pudge can take advantage of Enigma's lack of mobility, and gank him often.

* Doom pierces spell immunity and can prevent Enigma from casting any spells or using items until the duration of the spell depletes, as well as cancelling a Black Hole. This can however, be blocked by a Linken's Sphere, a common item on Enigma.

* Besides Lone Druid and Meepo, Doom is potentially good versus every hero since Doom will render any hero helpless for a prolonged 16 seconds. This is particularly true for fragile heroes that heavily rely on mobility to stay alive.

* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as Batrider, Beastmaster, Pudge and Clockwerk.

* If Phantom Assassin jumps on Pudge first with Phantom Strike, she will be a very easy target for Pudge's Meat Hook and Dismember combo.
* Even though it can deal damage based on Pudge's max health, Fan of Knives from Aghanim's Shard cannot disable Pudge's Flesh Heap as Flesh Heap is one of the few passive abilities that cannot be disabled by break.
* Both Meat Hook and Dismember ignore spell immunity which allows Pudge to disable Phantom Assassin even while she has Black King Bar active.
* Pudge occassionally buys armor items like Blade Mail, which in combination with many stacks from Flesh Heap can make Phantom Assassin have little effect against Pudge.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Meat Hook can be used immediately after Mortimer Kisses since Snapfire is forced to stay in place.

* Doom prevents Storm Spirit from using all of his abilities and items, rendering Storm Spirit useless in a fight.

* Doom is effective against every hero, and Void Spirit is no exception. Being unable to cast spells or items during fights for 16 seconds nullifies his impact entirely.
* Doom has a very versatile build and can consume creeps which has abilities that can stun or provide additional magic resistance.
* Doom's high strength gain and versatility in items can be effective against Void Spirit's magical damage.

* His Rot can force Templar Assassin out of her Meld and destroy all of her Refraction charges quickly, and her small health pool and meager defense make her very vulnerable to his Meat Hook without Refraction.

* Doom can stop Death Prophet from casting spells, which makes her useless during team fights if she didn't cast Exorcism before the fight. Furthermore, Doom can use Scorched Earth to chase after her.

* Rot and Meat Hook hits Dark Willow even when she uses Shadow Realm.
* Flesh Heap reduces Dark Willow's magic burst damage.

* Doom makes Ogre Magi less disruptive.
* Infernal Blade effectively negates Ogre Magi's durability.
* With Aghanim's Scepter, he can disable Multicast.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Axe more than most normal attacks, negating some of his durability.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Axe.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom's naturally low attack speed makes Counter Helix less likely to proc, and his high base health allows him to take a few Helixes with no danger.
* Doom makes Axe less disruptive, preventing him from using his skills or items. With Aghanim's Scepter, Counter Helix is also disabled, making him effectively useless for a lengthy duration.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Axe.
* Doom has low attack speed because of his high Base-Attack-Time, poor agility gain and limited attack-speed granting items which are commonly built. This means Doom will trigger Counter Helix less often and thus is an unideal target for initiation.
* Doom has naturally high HP so it takes longer for Doom to be brought down to the killing threshold of Culling Blade.
* Axe is highly reliant on his abilities and items to be effective during a fight. Without the usage of Berserker's Call and Blink Dagger due to Doom, Axe offers very little in the way of damage, effectively removing him from a fight.

* Doom completely takes Invoker out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Additional:
* Doom is a good way to shut down Invoker, preventing from casting spells and using items for a lengthy time, thus forcing him to invest on Linken's Sphere.

* Even with Black King Bar, Pudge's Meat Hook can still catch Bane while channeling Fiend's Grip, as a result, breaking the channel, Meat Hook can also be used to save targets affected by Bane's abilities.
* Dismember can disable Bane while channeling Fiend's Grip if Pudge is not targeted.
* Pudge's high health and health regeneration allows him to survive through most of Bane's abilities.

* Flesh Heap's magic resistance allows him to survive Eclipse, and Meat Hook and Dismember can disable Luna through her Black King Bar.
* However, Lucent Beam can still cancel Dismember from a safe distance, even if its damage is going to be reduced.

* Zeus likes to stay far back in fights, dealing his damage uninterrupted, but once he gets hooked into the fight, he usually dies very quickly.
* Pudge's high strength from Flesh Heap makes it very hard for Zeus to burst him down.
* Zeus' low health pool makes him very vulnerable to the damage from Meat Hook, Rot and Dismember.
Additional:
* Meat Hook's high range allows Pudge's team to drag Zeus in the middle of the fight and abuse his frailty.
* Flesh Heap's health and magic resistance bonus makes Pudge exceptionally resistant to Zeus' nukes. In later stages of the game, Zeus is usually unable to seriously damage Pudge at all. Even Static Field, which deals damage based on a percentage of the enemy's health, won't be doing much.
* Even if Zeus buys a Black King Bar, Meat Hook and Dismember still disable him for a long time, usually causing Zeus' quick death.
* Zeus is vulnerable to early ganks, which Pudge excels at.

* Meat Hook can hit and displace Juggernaut during his Blade Fury.
* Dismember pierces Juggernaut's spell immunity from Blade Fury.

* Heroes who build a Black King Bar (or have any sources of spell immunity) to channel abilities/items can still get interrupted by Dismember: Enigma, Juggernaut, Phantom Assassin, Pugna, Elder Titan.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Elder Titan. It also can interupt Echo Stomp if quick enough.
* Doom has very low base armor and naturally high HP, so he isn't significantly affected by Natural Order.

* Arc Warden relies on items and abilities, as well as his Tempest Double, to deal damage to enemies. Doom effectively denies that and makes Arc Warden useless in fights.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.

* Heroes who build a Black King Bar (or have any sources of spell immunity) to channel abilities/items can still get interrupted by Dismember: Enigma, Juggernaut, Phantom Assassin, Pugna, Elder Titan.

* Heroes with silences: Puck, Doom, Riki.

* Bristleback, Centaur Warrunner, Spirit Breaker, Pudge, Huskar: These heroes are too tanky for Puck to burst down. Also, all of them have spells which can deal with and shut Puck down reliably.

* Heroes with other kind of disables that pierce spell immunity can hold Pangolier in place during Rolling Thunder: Axe, Beastmaster, Enigma, Magnus, Pudge, Batrider, Bane, Winter Wyvern

* Abilities that deal low damage with high amounts of instances are irrelevant against Pudge during Flesh Heap's active: Gyrocopter's Rocket Barrage and Dark Seer's Ion Shell are just a couple examples.

* Abilities that deal low damage with high amounts of instances are irrelevant against Pudge during Flesh Heap's active: Gyrocopter's Rocket Barrage and Dark Seer's Ion Shell are just a couple examples.

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

* Heroes that have a channeled ability that can be interrupted by Meat Hook: Shadow Shaman, Witch Doctor, Enigma, Bane.

* Heroes with abilities that break Berserker's Blood, lowering Huskar's attack speed and health regeneration: Doom, Shadow Demon, Viper.

* Doom can eats Nature's Prophet's treants with Devour and gains lots of gold.
* Doom can buy Radiance or use his Scorched Earth to quickly wipe out a swarm of Treants.
* Doom and a ministun from Infernal Blade's prevents Nature's Prophet from escaping with Sprout and Teleportation.

* Ember Spirit cannot use his Activate Fire Remnant to escape while under effect from Doom.

* Sniper has a low health pool and strength gain, making him vulnerable to Pudge's magical and pure damage.
* Sniper usually likes to deal damage away from the fight, and Meat Hook is capable of bringing him to the front lines.
* Assassinate won't do much damage against Pudge because of his high strength gain and the strength bonuses from Flesh Heap.
* Shrapnel will be mostly blocked by Flesh Heap's active.
Additional:
* Pudge's Meat Hook allows him to bring Sniper in the middle of any fight, and the pure damage does well against his high armor and low health.
* Dismember can lock Sniper down, which makes him highly vulnerable and gives enough time for Pudge to kill him alone.

* Doom can completely shut down Dazzle through Doom, as it prevents him from casting his abilities and, by extension, gaining Bad Juju stacks.

* Scorched Earth deals damage to Clinkz during Skeleton Walk.
* Doom shuts down Clinkz entirely, as it prevents him from casting any of his spells and contributing a large amount of damage in teamfights.

* Doom turns Omniknight into a walking creep, or completely takes out his buffed cores, also removing Heavenly Grace and Guardian Angel in the process.
* With Devour used on Satyr Banisher, Doom will have access to Satyr Banisher's Purge, which will allow him to remove Heavenly Grace and Guardian Angel.
Additional:
* Doom applies a basic dispel upon cast, so it can remove Guardian Angel.
* Casting Doom on Omniknight will also prevent him from healing allies with Purification, or casting buffs like Heavenly Grace and Guardian Angel, basically turning him into a harmless creep.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Bristleback.
* Doom prevents Bristleback from casting his two low cooldown abilities, which then prevents him from utilizing Warpath.
* If Doom gets an Aghanim's Scepter, he can disable Bristleback and Warpath, taking away much of his durability and damage potential in team fights.
Additional:
* Infernal Blade deals scaling damage and is useful against high health targets such as Bristleback.
* Doom disables Bristleback's low cooldown abilities, preventing him from triggering Warpath. With Aghanim's Scepter, it also breaks Bristleback's passive, rendering him more vulnerable.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Timbersaw.
* Timbersaw is extremely reliant on his abilities to be effective during a team fight - both for mobility, damage and crowd control. Timbersaw offers very little impactful right-click damage, and thus Doom is particularly crippling against this hero.
* Additionally, when upgraded with Aghanim's Scepter, Doom breaks Reactive Armor, which effectively removes the durability which Timbersaw is commonly known for.
Additional:
* Doom shuts down Timbersaw completely, negating his mobility and preventing him from doing any damage. It also breaks Reactive Armor's passive bonuses from Aghanim's Scepter.
* Infernal Blade can stun Timbersaw several times in a fight, potentially interrupting Timber Chain. Also it's useful since Timbersaw has high HP due to the damage scales based on max HP.

* Heroes who recklessly jump on Pudge with their gap-closing abilities will be easy targets for Pudge's Meat Hook and Dismember Combo: Phantom Assassin, Faceless Void, Queen of Pain etc.

* Heroes that have a channeled ability that can be interrupted by Meat Hook: Shadow Shaman, Witch Doctor, Enigma, Bane.

Additional:
* Meat Hook interrupts Death Ward from a decent range, even through Black King Bar & Glimmer Cape.
* Pudge can survive the damage from Maledict because of his Flesh Heap stacks.
* However the damage-over-time from Rot is counteracted by Voodoo Restoration.

* An Aghanim's Scepter upgraded Doom can be useful against heroes with troublesome passive skills while also disabling them for a long time: Phantom Assassin, Enchantress, Huskar, Underlord.

Additional:
* Infernal Blade does damage based on percentage health, and is useful against high health pool hero like Underlord
* Doom can prevent Underlord from spamming his abilities and most important is prevent him from using Dark Rift to escape

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

* Doom shuts down Anti-Mage's escape capabilities with Blink. The ability also deals pure damage, which ignores the protection from Counterspell.
* However, a well-timed Counterspell can reflect it back.
* If Doom has Aghanim's Scepter, Doom can break Mana Break and Counterspell, weakening both his offense and defense.
* Doom's low mana pool causes him to take little damage from Mana Void.
Additional:
* Doom prevents Anti-Mage from maneuvering around a fight or escaping from an initiation using Blink. Additionally, Doom deals pure damage, which is not affected by Counterspell. This can quickly whittle away Anti-Mage's naturally poor health pool.
* Be careful when using Doom as a well-timed Counterspell can block and reflect it back against Doom himself.
* An Aghanim's Scepter upgraded Doom will also disable Mana Break and Counterspell, which makes Anti-Mage significantly less effective in fights and more susceptible to the high magical damage of Doom's abilities and his allies.

* Silencer's Global Silence and Doom's Doom makes Earthshaker temporarily useless.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Meat Hook brings Drow Ranger to Pudge, disabling Marksmanship and dealing a huge amount of damage when combined with Rot and Dismember.
* Rot keeps Pudge close to Drow Ranger, continuously disabling Marksmanship.
Additional:
* Meat Hook can pull Drow Ranger to Pudge, disabling her Marksmanship.
* Following up with Dismember will prevent Drow Ranger from using Gust or Shadow Blade.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Tidehunter.
* Doom prevents Tidehunter from casting his Gush, Anchor Smash and Ravage, making him useless in team fights.
* If Doom gets an Aghanim's Scepter, he can also disable Kraken Shell, reducing his survivability.

* Scorched Earth can be used to engage Visage while removing Gravekeeper's Cloak charges.
* Infernal Blade will deal tremendous amounts of damage over time due to Visage's high health pool.
* Doom completely nullifies Gravekeeper's Cloak and prevents Visage from casting spells.