* Ensnare with her attacks allows Naga Siren to gank Sniper easily.
* Rip Tide removes Sniper's very little armor.

* Pudge's Meat Hook allows him to bring Sniper in the middle of any fight, and the pure damage does well against his high armor and low health.
* Dismember can lock Sniper down, which makes him highly vulnerable and gives enough time for Pudge to kill him alone.
Additional:
* Sniper has a low health pool and strength gain, making him vulnerable to Pudge's magical and pure damage.
* Sniper usually likes to deal damage away from the fight, and Meat Hook is capable of bringing him to the front lines.
* Assassinate won't do much damage against Pudge because of his high strength gain and the strength bonuses from Flesh Heap.

* Mirror Image can dispel Frostbite.
* Song of the Siren can stop Freezing Field regardless of any kind of invisibility as well as allow Naga Siren's team to quickly close the gap on Crystal Maiden.
Additional:
* Mirror Image can dispel Frostbite.
* Ensnare and Song of the Siren can stop Freezing Field.
* Song of the Siren can allow her team to quickly close the gap on Crystal Maiden.

* Heroes with large health pools (Pudge) or good innate magic resistance (Anti-Mage) can be very problematic for Crystal Maiden, since even if they are under the effect of her ultimate for the entire duration, the damage output is simply not enough to kill or force them to retreat.

Additional:
* Meat Hook can cancel Freezing Field, even if Crystal Maiden has Glimmer Cape.
* She is also slow and is fragile, making her a good target for ganking.

* His Rot can force Templar Assassin out of her Meld and destroy all of her Refraction charges quickly, and her small health pool and meager defense make her very vulnerable to his Meat Hook without Refraction.

* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

Additional:
* Ensnare disables Templar Assassin's invisibility and Blink Dagger (a core item on Templar Assassin), and her illusions will break Refraction easily.

* Flesh Heap's magic resistance allows him to survive Eclipse, and Meat Hook and Dismember can disable Luna through her Black King Bar.
* However, Lucent Beam can still cancel Dismember from a safe distance, even if its damage is going to be reduced.
Additional:
* Pudge can easily survive Luna's Lucent Beam and Eclipse, and his Meat Hook and Dismember can pierce Black King Bar, making Luna one of the perfect victims for ganking.
* However, Lucent Beam can cancel Dismember, as Pudge often doesn't build Black King Bar, and if she is farmed enough, Luna might be able to fight back against Pudge.

* Heroes that create illusions (such as Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress and the aforementioned Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. (However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse).

* Meat Hook can hit and displace Juggernaut during his Blade Fury.
* Dismember pierces Juggernaut's spell immunity from Blade Fury.

* Illusion-based heroes are effective against Omnislash and Juggernaut's single-targeted damage: Naga Siren, Chaos Knight, Terrorblade,Phantom Lancer.

* He can Meat Hook a Tinker hiding in the trees and follow it up with Dismember and Rot for an easy solo kill, as Tinker doesn't tend to buy survivability items.
* His innate magic resistance and huge health pool from Flesh Heap makes it hard for Tinker to deal serious damage to Pudge.
Additional:
* Meat Hook can used to pull Tinker while he is hiding in the trees, and a follow up with Dismember and Rot leads to an easy solo kill, as Tinker doesn't buy many survivability items.
* Flesh Heap makes it hard for Tinker to deal serious damage.

* Illusion heroes, such as Naga Siren, Phantom Lancer, Chaos Knight, Terrorblade will become strong against Tinker in the late game when Tinker's only area of effect damage, March of the Machines, ceases to kill illusions quickly. Without Aghanim's Scepter Tinker is forced to defensively disarm heroes with Laser, leaving illusions free to deal physical damage which Tinker's low armor makes highly effective. In addition, Mjollnir or Battle Fury, two common pickups against illusion heroes, don't work well on Tinker at all.

* Techies struggles early game against heroes with naturally large strength and health regeneration such as Pudge, Axe or Ogre Magi, as the player is forced to lay down more mines than usual to kill these bulkier heroes.

Additional:
* Pudge is the perfect hero for tanking mines, as Flesh Heap grants him lots of strength.
* Techies' high ground defense can be bypassed by Pudge hooking his enemies to him.
* Techies usually sits in the trees during the laning stage, setting up Proximity Mines. Meat Hook can easily pull them out and set them up for a kill.

* Heroes with summons like Broodmother,Enigma, Invoker, Nature's Prophet, Lycan, Visage;or illusions, like Naga Siren, Phantom Lancer, Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity mines in the early game.

* Meat Hook can pull an ally out of Chronosphere.
* Rot will keep damaging Void if he toggled it before Chronosphere,but you can lower your hp for faceless void.
* Flesh Heap will help Pudge survive through the Chronosphere with enough stacks, and follow with Dismember.

* Unless Lone Druid purchases a Black King Bar for his Spirit Bear, Ensnare will easily kite the Bear.
* Song of the Siren allows Naga Siren and her team to completely bypass the Spirit Bear and hunt for the Druid himself when starting a fight.
* Lone Druid's lack of innate AoE capabilities mean that Naga Siren's illusions have no problem against him.

* Song of the Siren is very difficult for Rubick to Spell Steal when he is affected by sleep. However, if Rubick does successfully steal it, the Song will allow his team to initiate from unexpected angles.
* Ensnare and Rip Tide together with some attacks can take Rubick down quickly, due to his low health pool and armor.
* Naga Siren usually buys Diffusal Blade, which may prevent Rubick from using his abilities.
* Mirror Image allows Naga Siren to dodge the incoming stun from Telekinesis (when she is not a target), and it can also dispel Fade Bolt's damage reduction debuff.

* Pudge's Dismember does not allow Spectre to escape with Haunt.
* He can easily tank the damage reflected by Dispersion due to his high strength and the healing from Dismember.
* Should Spectre try to get away through the trees or over a cliff with Spectral Dagger, Pudge can hook her back.
* Spectre takes a long time to come online, and Pudge can ruin her early game with ganks.

* Naga Siren can easily disjoint, and dispel Corrosive Skin with Mirror Image.
* Since Viper is a single-target hero, he will not stand a chance against Naga Siren because she is an illusion based hero.
* However, Nethertoxin can clear her illusions quickly if Naga Siren does not micromanage them well.

* Meat Hook brings Drow Ranger to Pudge, disabling Marksmanship and dealing a huge amount of damage.
* Rot keeps Pudge close to Drow Ranger, continuously disabling Marksmanship.
Additional:
* Meat Hook can pull Drow Ranger to Pudge, disabling her Marksmanship.
* Following up with Dismember will prevent Drow Ranger from using Gust or Shadow Blade.

* Song of the Siren can be used to time out Guardian Angel, giving Naga Siren's team an easy opportunity to counter-initiate.
Additional:
* Song of the Siren will waste Guardian Angel.
* Ensnare fully works on Heavenly Graced targets. However, Ensnare is dispellable with any dispel, and so can be dispelled by Heavenly Grace.
* As an agility hero that relies on illusions, Naga Siren is one of the most natural Diffusal Blade carriers, the bane of every hero with a small mana pool.

* Song of the Siren can be used to nullify the effects of Winter's Curse, and when upgraded with Aghanim's Scepter it also outmatches the heal of Cold Embrace.
* If Winter Wyvern is reckless enough to put an ally in Cold Embrace, Naga Siren will be able to use her Ensnare to extend the disable on the hero affected by Cold Embrace.

* Rot and Meat Hook hits Dark Willow even when she uses Shadow Realm.
* Flesh Heap reduces Dark Willow's magic burst damage.

* Mirror Image can cause Huskar to Life Break the wrong target.
* Rip Tide reduces Huskar's already low armor.
* Song of the Siren allows teams to recover from Huskar's initiation, as well as the damage over time from Burning Spears.

* Song of the Siren stops Arc Warden from acting and allows Naga Siren's team to close in on him, past his Magnetic Field.
* Mirror Image dispels Flux. The illusions created from it also disable the slow from Flux if Arc Warden casts it after Mirror Image.
* Arc Warden's playstyle heavily favors split-pushing, which Naga Siren can compete against with her illusions.
Additional:
* Her illusions can push better than Arc Warden's Tempest Double because Mirror Image has a longer duration.
* Mirror Image dispels Flux, and the illusions stop Flux from working.

* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark,Drow Ranger.

* Heroes with channeling spells because Shadow Fiend has nothing to cancel channeling: Bane, Enigma, Pudge, Shadow Shaman.

* Heroes that have a channeled ability can be interrupted by Meat Hook: Shadow Shaman, Witch Doctor, Enigma, Bane.

Additional:
* Meat Hook interrupts Death Ward from a decent range, even through Black King Bar & Glimmer Cape.
* Pudge can survive the damage from Maledict because of his Flesh Heap stacks.
* However the damage-over-time from Rot is counteracted by Voodoo Restoration.

* Any hero reliant of mobility, like Storm Spirit.

* Naga Siren with Mirror Image
* Heroes that can dodge Glimpse:
* Puck with Phase Shift
* Riki with Tricks of the Trade
* Phantom Lancer with Doppelganger
* Ember Spirit with Sleight of Fist and Activate Fire Remnant
* Chaos Knight with Phantasm
* Naga Siren with Mirror Image
* Tusk with Snowball
* Juggernaut with Omnislash
* Brewmaster with Primal Split
* Lifestealer with Infest
* Phoenix with Supernova

* Heroes with powerful rooting abilities will disable most of Pangolier's skill, a bonus point if it pierce spell immunity since it will also be able to stop Pangolier during his Rolling Thunder: Treant Protector, Meepo, Crystal Maiden, Dark Willow, Underlord, Naga Siren

* Heroes with other kind of disables that pierce spell immunity can hold Pangolier in place during Rolling Thunder: Axe, Beastmaster, Enigma, Magnus, Pudge, Batrider, Bane, Winter Wyvern

* Heroes with summons and illusions such as Broodmother and Naga Siren, are ill-suited for Wraith King to fight, as he has no source of waveclear.

* Bristleback, Centaur Warrunner, Spirit Breaker, Pudge, Huskar: These heroes are too tanky for Puck to burst down. Also, all of them have spells which can deal with and shut Puck down reliably.

* Pudge, Legion Commander and Axe will make the match a living hell for you, since they are known for surprise attacks from the fog and quickly killing low HP heroes. They can also interrupt your channeling, Legion being especially problematic, as she can use Press the Attack on an ally who is hexed as well.

* Heroes that have a channeled ability can be interrupted by Meat Hook: Shadow Shaman, Witch Doctor, Enigma, Bane.

Additional:
* Meat Hook can easily hit nightmared targets, as well as Bane while channeling Fiend's Grip.
* Dismember interrupts Fiend's Grip if Pudge is not targeted.
* Pudge's high health and health regeneration let him absorb much of Bane's nukes.

* Lycan is a hero focused entirely on single target physical damage and lacks disables or AoE damage. Due to this, he can't deal with illusions or Naga Siren's Ensnare.

* Naga Siren is a natural split-pusher. With a Radiance equipped, she will easily out-push Nature's Prophet, farming his treants in the process.
* Ensnare prevents Teleportation. Even if he hid inside Sprout, Song of the Siren lasts long enough to prevent him from escaping.
Additional:
* Naga Siren is a natural split-pusher. With Rip Tide, she will easily out-push Nature's Prophet, farming his treants in the process.
* Ensnare prevents Teleportation. Even if he hides inside Sprout, Song of the Siren lasts long enough to prevent him from escaping.

* Pudge's high health pool will make him have possibilities of escaping Rupture.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge.

* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as Batrider, Beastmaster, Pudge and Clockwerk.

* Meat Hook can be used immediately after Mortimer Kisses since Snapfire is forced to stay in place.

* Meat Hook's high range allows Pudge's team to drag Zeus in the middle of the fight and abuse his frailty.
* Flesh Heap's health and magic resistance bonus makes Pudge exceptionally resistant to Zeus' nukes. In later stages of the game, Zeus is usually unable to seriously damage Pudge at all. Even Static Field, which deals damage based on a percentage of the enemy's health, won't be doing much.
* Even if Zeus buys a Black King Bar, Meat Hook and Dismember still disable him for a long time, usually causing Zeus' quick death.
* Zeus is vulnerable to early ganks, which Pudge excels at.
Additional:
* Zeus likes to stay far back in fights, dealing his damage uninterrupted, but once he gets hooked into the fight, he usually dies very quickly.
* Pudge's high strength from Flesh Heap make it very hard for Zeus to burst him down.
* Zeus' low health pool makes him very vulnerable to the damage from Meat Hook, Rot and Dismember.

* Mirror Image's illusions can easily walk straight at Dazzle and attack him, due to Dazzle's lack of reliable AoE nukes or disables.
* Ensnare roots Dazzle or his allies, making it harder to stay in range of Dazzle's saving abilities.
* Song of the Siren can be used to initiate a fight with superior positioning, potentially zoning Dazzle's high-impact spells out of the fight.

* Heroes who build a Black King Bar (or having any sources of spell immunity) to channel abilities/items are still interrupted by Dismember: Enigma, Juggernaut, Pugna, Elder Titan.

* Meat Hook can easily cancel Wukong's Command by pulling Monkey King out of the circle.
* Meat Hook can grab Monkey King from trees during Tree Dance.
* Rot puts Tree Dance on cooldown.

* Song of the Siren completely wastes Abaddon Borrowed Time while keeping him in place.
* Naga Siren is able to simply dispel Abaddon's Curse of Avernus with Mirror Image before getting hit 4 times consecutively.
* Although Naga Siren's illusions can be easily destroyed by Aphotic Shield, Naga Siren can resolve that issue easily by purchasing Heart of Tarrasque to drastically increase her durability. Plus, the said item makes Naga Siren harder to be distinguished from her illusions.

* Mirror Image can be effective since Night Stalker cannot withstand fighting illusions. If he's unable to tell which Naga Siren is real, he will have a hard time landing his Void. However, if Night Stalker obtains an Aghanim's Scepter, the upgraded Void will hit and may even locate the real Naga Siren in fights.
Additional:
* Ensnare and Song of the Siren prevents Night Stalker from escaping and ganking during daytime or even nighttime.
* Rip Tide reduces Night Stalker's armor, making him easier to focus down.
* Mirror Image can be effective against Night Stalker, due to his single target abilities.

* Heroes who build a Black King Bar (or having any sources of spell immunity) to channel abilities/items are still interrupted by Dismember: Enigma, Juggernaut, Pugna, Elder Titan.