* Any hero that can nullify effects of Chronosphere: (Omniknight, Keeper of the Light with Aghanim's Scepter during daytime, Winter Wyvern), banishing him or Faceless Void (Outworld Destroyer, Shadow Demon, Earth Spirit with Aghanim's Scepter) or protecting him in other ways (Dazzle, Oracle, Abaddon) can greatly limit Chronosphere's potential.

* Meat Hook can pull an ally out of Chronosphere.
* Rot will keep damaging Void if he toggled it before Chronosphere,but you can lower your hp for faceless void.
* Flesh Heap will help Pudge survive through the Chronosphere with enough stacks, and follow with Dismember.

* Heroes with other kind of disables that pierce spell immunity can hold Pangolier in place during Rolling Thunder: Axe, Beastmaster, Enigma, Magnus, Pudge, Batrider, Bane, Winter Wyvern

* Astral Imprisonment protects an ally for much of Rolling Thunder's duration, especially at the lower levels. As Rolling Thunder has a considerable cast animation, an Outworld Destroyer with Blink Dagger can initiate on him and destroy his timing.

* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.

* Flesh Heap's magic resistance allows him to survive Eclipse, and Meat Hook and Dismember can disable Luna through her Black King Bar.
* However, Lucent Beam can still cancel Dismember from a safe distance, even if its damage is going to be reduced.
Additional:
* Pudge can easily survive Luna's Lucent Beam and Eclipse, and his Meat Hook and Dismember can pierce Black King Bar, making Luna one of the perfect victims for ganking.
* However, Lucent Beam can cancel Dismember, as Pudge often doesn't build Black King Bar, and if she is farmed enough, Luna might be able to fight back against Pudge.

* Astral Imprisonment allows Outworld Destroyer to save himself or his teamates during Omnislash.
* Juggernaut's low mana from his low intelligence gain means that he'll take a lot of damage from Sanity's Eclipse.

* Meat Hook can hit and displace Juggernaut during his Blade Fury.
* Dismember pierces Juggernaut's spell immunity from Blade Fury.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge.

* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.

* Astral Imprisonment can allow Outworld Destroyer to save himself or allies from Kunkka's full kit.
* Sanity's Eclipse deal a large amount of damage, as Kunkka's mana pool is much smaller than Outworld Destroyer's.
* Arcane Orb deals pure damage, shredding through Kunkka and his team even with Ghostship's buff.

* Meat Hook can be used immediately after Mortimer Kisses since Snapfire is forced to stay in place.

* Arcane Orb deals heavy damage to both Lone Druid and the Spirit Bear.
* Astral Imprisonment can prevent the Spirit Bear from attacking, which is Lone Druid's main damage output.
* Sanity's Eclipse deals heavy damage to Lone Druid.

* Arcane Orb deals pure damage, effectively bypassing Morphling's high armor from Attribute Shift (Agility Gain).
* Sanity's Eclipse is more effective against a low health and mana pool Morphling, enabling Outworld Destroyer to burst Morphling down before he can shift to Strength.
Additional:
* Arcane Orb deals high damage regardless of Morphling's high armor from Attribute Shift (Agility Gain).
* Because of Morphling's very low intelligence gain and base intelligence, Sanity's Eclipse will almost always be effective against Morphling.

* Meat Hook's high range allows Pudge's team to drag Zeus in the middle of the fight and abuse his frailty.
* Flesh Heap's health and magic resistance bonus makes Pudge exceptionally resistant to Zeus' nukes. In later stages of the game, Zeus is usually unable to seriously damage Pudge at all. Even Static Field, which deals damage based on a percentage of the enemy's health, won't be doing much.
* Even if Zeus buys a Black King Bar, Meat Hook and Dismember still disable him for a long time, usually causing Zeus' quick death.
* Zeus is vulnerable to early ganks, which Pudge excels at.
Additional:
* Zeus likes to stay far back in fights, dealing his damage uninterrupted, but once he gets hooked into the fight, he usually dies very quickly.
* Pudge's high strength from Flesh Heap make it very hard for Zeus to burst him down.
* Zeus' low health pool makes him very vulnerable to the damage from Meat Hook, Rot and Dismember.

* Pudge's Dismember does not allow Spectre to escape with Haunt.
* He can easily tank the damage reflected by Dispersion due to his high strength and the healing from Dismember.
* Should Spectre try to get away through the trees or over a cliff with Spectral Dagger, Pudge can hook her back.
* Spectre takes a long time to come online, and Pudge can ruin her early game with ganks.

* Arcane Orb's pure damage penetrates Guardian Angel's defense.
* Outworld Destroyer's intelligence steal is also devastating to Omniknight's already low mana pool.

* Outworld Destroyer's pure and magical damage is particularly effective against Axe.
* Astral Imprisonment is an excellent way to defend against an initiating Axe.
* Sanity's Eclipse deals high damage to Axe due to his low mana pool.
Additional:
* Berserker's Call bonus armor doesn't block Arcane Orb's pure damage.
* Astral Imprisonment can be used to prevent an ally or Outworld Devourer himself from an Axe initiation.
* Axe's low mana means he's susceptible to a powerful Sanity's Eclipse.

* Arcane Orb's pure damage ignores Mars' Bulwark.
* Astral Imprisonment can be used to stop Mars from being disruptive or save allies from his abilities.
* Sanity's Eclipse deals high damage to Mars, due to his low intelligence.

* Arcane Orb's constant pure damage output is devastating to Dragon Knight.
* Dragon Knight's relatively low mana pool leads to heavy damage from Sanity's Eclipse, which also bypasses his armor.

* Outworld Devourer's pure damage from Arcane Orb can go through Cold Embrace.
* Outworld Devourer can negate the healing from Cold Embrace using Astral Imprisonment, and steal mana while doing so.
* Outworld Devourer's damage during Winter's Curse is reduced due to Arcane Orb being unable to target allies.
Additional:
* Winter Wyvern must never put her allies in Cold Embrace against Outworld Destroyer as Arcane Orb will continue to steal Intelligence and deal damage to the defenseless hero.
* Arcane Orb does not hit his allies when he is taunted by Winter's Curse, making it weak against allies, but strong versus enemies.
* Astral Imprisonment can protect a target inflicted with Winter's Curse.

* Outworld Destroyer's pure damage will mop up Primal Split's units very quickly.

* Astral Imprisonment can be used to protect allies by imprisoning either them or Spirit Breaker.
* Arcane Orb will heavily drain Spirit Breaker's intelligence, rendering him almost useless and unable to cast spells. Spirit Breaker's low intelligence also means Sanity's Eclipse will deal a lot of damage to him.

* Pudge's high health pool will make him have possibilities of escaping Rupture.

* Sanity's Eclipse does massive damage to Wraith King who naturally has a low mana pool and typically doesn't build items to increase it.
* Wraithfire Blast's slow projectile speed makes it easy to avoid using Astral Imprisonment.

* Arcane Orb 's pure damage can do great damage to Underlord.
* Sanity's Eclipse can tear down Underlord's health by a large amount, since his mana pool is very low compare to OD's high mana pool.

* Outworld Destroyer's pure damage from Arcane Orb is very effective at killing Troll Warlord quickly.
* Astral Imprisonment removes Troll Warlord from a fight for four seconds, minimizing his contribution to a teamfight, and potentially wasting over half of Battle Trance's duration.
* Troll Warlord gains a measly 1 intelligence point per level, meaning Sanity's Eclipse is especially effective, often instantly killing him.

* Rot and Meat Hook hits Dark Willow even when she uses Shadow Realm.
* Flesh Heap reduces Dark Willow's magic burst damage.

* Sanity's Eclipse will likely instantly kill all illusions.

* Tanky melee heroes that can easily be kited, which allows Outworld Devourer to deal heavy damage with Arcane Orb from a distance: Sven, Underlord, Bristleback.

* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as Batrider, Beastmaster, Pudge and Clockwerk.

* Heroes with channeling spells because Shadow Fiend has nothing to cancel channeling: Bane, Enigma, Pudge, Shadow Shaman.

* Heroes that have a channeled ability can be interrupted by Meat Hook: Shadow Shaman, Witch Doctor, Enigma, Bane.

Additional:
* Meat Hook interrupts Death Ward from a decent range, even through Black King Bar & Glimmer Cape.
* Pudge can survive the damage from Maledict because of his Flesh Heap stacks.
* However the damage-over-time from Rot is counteracted by Voodoo Restoration.

* Shadow Demon, Outworld Destroyer and Tusk can all save a Lasso'd teammate with their defensive spells.

* Techies struggles early game against heroes with naturally large strength and health regeneration such as Pudge, Axe or Ogre Magi, as the player is forced to lay down more mines than usual to kill these bulkier heroes.

Additional:
* Pudge is the perfect hero for tanking mines, as Flesh Heap grants him lots of strength.
* Techies' high ground defense can be bypassed by Pudge hooking his enemies to him.
* Techies usually sits in the trees during the laning stage, setting up Proximity Mines. Meat Hook can easily pull them out and set them up for a kill.

* Heroes with mana burn: Nyx Assassin, Invoker, Outworld Destroyer, Pugna

* Heroes with large health pools (Pudge) or good innate magic resistance (Anti-Mage) can be very problematic for Crystal Maiden, since even if they are under the effect of her ultimate for the entire duration, the damage output is simply not enough to kill or force them to retreat.

Additional:
* Meat Hook can cancel Freezing Field, even if Crystal Maiden has Glimmer Cape.
* She is also slow and is fragile, making her a good target for ganking.

* Bristleback, Centaur Warrunner, Spirit Breaker, Pudge, Huskar: These heroes are too tanky for Puck to burst down. Also, all of them have spells which can deal with and shut Puck down reliably.

* Pudge, Legion Commander and Axe will make the match a living hell for you, since they are known for surprise attacks from the fog and quickly killing low HP heroes. They can also interrupt your channeling, Legion being especially problematic, as she can use Press the Attack on an ally who is hexed as well.

* Heroes with pure damage can kill Huskar when he inevitably gets low on health: Outworld Destroyer, Silencer.

Additional:
* Outworld Devourer can dodge Life Break with Astral Imprisonment, leaving him unharmed while Huskar loses HP.
* Sanity's Eclipse can deal massive damage to Huskar before he builds up his Berserker's Blood stacks due to Huskar's low mana pool.

* Heroes that have a channeled ability can be interrupted by Meat Hook: Shadow Shaman, Witch Doctor, Enigma, Bane.

Additional:
* Meat Hook can easily hit nightmared targets, as well as Bane while channeling Fiend's Grip.
* Dismember interrupts Fiend's Grip if Pudge is not targeted.
* Pudge's high health and health regeneration let him absorb much of Bane's nukes.

* Heroes with hiding abilities can protect disabled allies: Outworld Destroyer, Shadow Demon, Tusk, Phoenix with Aghanim's Scepter

* Heroes who build a Black King Bar (or having any sources of spell immunity) to channel abilities/items are still interrupted by Dismember: Enigma, Juggernaut, Pugna, Elder Titan.

Additional:
* Pudge can Meat Hook Enigma out of his Black Hole channeling and cancel it through Black King Bar when followed up with Dismember.
* Enigma is prone to ganks in the jungle or in the off-lane without proper vision. Pudge can take advantage of Enigma lack of mobility, assuming Enigma is not blocked by his Eidolons.
* Stacked magic resistance from his passive Flesh Heap ability can mitigate Midnight Pulse's damage.

* The pure damage provided by Arcane Orb is a great addition for killing Ember Spirit.
* Astral Imprisonment fully negates all magic damage of Flame Guard and Searing Chains and will temporarily save himself from Sleight of Fist's physical damage, and Ember Spirit is not a hero that can counter these skills.

* Meat Hook brings Drow Ranger to Pudge, disabling Marksmanship and dealing a huge amount of damage.
* Rot keeps Pudge close to Drow Ranger, continuously disabling Marksmanship.
Additional:
* Meat Hook can pull Drow Ranger to Pudge, disabling her Marksmanship.
* Following up with Dismember will prevent Drow Ranger from using Gust or Shadow Blade.

* Outworld Destroyer's pure and magical damage is particularly effective against Earthshaker.
* Astral Imprisonment catches Earthshaker while he blinks in, preventing him from executing his combo.
* Earthshaker has mana troubles, and Outworld Destroyer's abilities can press this by stealing intelligence comes from Arcane Orb, therefore depleting his mana pool and mana regeneration.
* Sanity's Eclipse deals high damage to Earthshaker, due to his low intelligence and mana pool.

* Astral Imprisonment allows Outworld Destroyer to save himself or ally from Invoker's combo, or remove Invoker from a fight temporarily.
* Arcane Orb's pure damage will deal a lot of damage against Invoker's mediocre strength gain.
* EMP is useless against Outworld Destroyer by activating Equilibrium.
* However, be aware that Sanity's Eclipse will most likely not deal any damage at all, due to Invoker's high intelligence gain compared to Outworld Destroyer's.

* His Rot can force Templar Assassin out of her Meld and destroy all of her Refraction charges quickly, and her small health pool and meager defense make her very vulnerable to his Meat Hook without Refraction.

* He can Meat Hook a Tinker hiding in the trees and follow it up with Dismember and Rot for an easy solo kill, as Tinker doesn't tend to buy survivability items.
* His innate magic resistance and huge health pool from Flesh Heap makes it hard for Tinker to deal serious damage to Pudge.
Additional:
* Meat Hook can used to pull Tinker while he is hiding in the trees, and a follow up with Dismember and Rot leads to an easy solo kill, as Tinker doesn't buy many survivability items.
* Flesh Heap makes it hard for Tinker to deal serious damage.

* Outworld Destroyer doesn't care if Razor steals his damage because he does most of his damage through Arcane Orb.
* Astral Imprisonment can prevent Razor from using the stolen damage from Static Link or chasing with Eye of the Storm.
* Sanity's Eclipse will do a ton of damage to Razor due to his low mana pool.

* Sanity's Eclipse only triggers Bristleback's passive once, and deals high damage against Bristleback's low intelligence.

* Arcane Orb deals pure damage against the real Terrorblade, bypassing his high base armor.
* Arcane Orb and Sanity's Eclipse will make very short work of Terrorblade and his illusions.

* Astral Imprisonment is a versatile nuisance:
* If it is cast on a low-enough-health unit at least 1 second into Shallow Grave's duration, the Shallow Grave will end during the imprisonment, and the target will take lethal damage when released.
* It can be used remove Dazzle from the fight at a time he could have saved someone.
* It lets himself or an ally dodge all of Poison Touch's effects, for long enough to recover their Blink Dagger.

* Arcane Orb deals pure damage, which ignores armor granted from permanent agility stacks.
* Astral Imprisonment can disrupt any Pounce attempt by banishing the leashed ally.
* Slark's low intelligence and therefore mana pool makes him more susceptible to Sanity's Eclipse.

* Arcane Orb deals constant pure damage, which bypasses Timbersaw's Reactive Armor.
* Sanity's Eclipse can hit targets inside Astral Imprisonment, which helps Outworld Destroyer finish off Timbersaw before he escapes with Timber Chain. It can also drain his mana, limiting his ability to escape should he survive.
Additional:
* Arcane Orb's pure damage ignores Timbersaw's Reactive Armor.
* Astral Imprisonment, if timed correctly, can interrupt Timber Chain, preventing him from escaping.

* Arcane Orb's pure damage goes through Counterspell, and deals splash damage to illusions spawned from Manta Style.
* Sanity's Eclipse hits Anti-Mage while he is disabled with Astral Imprisonment, and forces him to take heavy damage due to his low intelligence.
* Essence Flux keeps Outworld Destroyer at high mana, thus greatly reducing the damage from Mana Void.
Additional:
* Counterspell doesn't work versus Arcane Orb because it does pure damage.
* Anti-Mage cannot burn all of Outworld Devourer's mana without disables due to Essence Flux.
* Anti-Mage's Manta Style illusions are quickly destroyed by Arcane Orb.
* However, if the enemy has multiple means of removing mana, Mana Void becomes a threat to Outworld Devourer, Anti-Mage has better mobility than Outworld Devourer with Blink, and Counterspell blocks a large portion of the damage from Sanity's Eclipse.

* Pudge's Meat Hook allows him to bring Sniper in the middle of any fight, and the pure damage does well against his high armor and low health.
* Dismember can lock Sniper down, which makes him highly vulnerable and gives enough time for Pudge to kill him alone.
Additional:
* Sniper has a low health pool and strength gain, making him vulnerable to Pudge's magical and pure damage.
* Sniper usually likes to deal damage away from the fight, and Meat Hook is capable of bringing him to the front lines.
* Assassinate won't do much damage against Pudge because of his high strength gain and the strength bonuses from Flesh Heap.

* Heroes who build a Black King Bar (or having any sources of spell immunity) to channel abilities/items are still interrupted by Dismember: Enigma, Juggernaut, Pugna, Elder Titan.

* Meat Hook can easily cancel Wukong's Command by pulling Monkey King out of the circle.
* Meat Hook can grab Monkey King from trees during Tree Dance.
* Rot puts Tree Dance on cooldown.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Astral Imprisonment wastes Borrowed Time's duration.
* Outworld Destroyer's Sanity's Eclipse can kill Abaddon before Borrowed Time triggers.