* Heroes with high burst damage: Lina, Lion, Luna, Nyx Assassin, Queen of Pain.

* Lucent Beam and Eclipse with ministun talent can be used to cancel Requiem of Souls if Shadow Fiend does not have Black King Bar.
* Moon Glaives and Lunar Blessing allow Luna to outfarm Shadow Fiend in lane.
* A well timed Eclipse will burst and kill Shadow Fiend before he even gets a chance to retaliate, especially when equipped with Aghanim's Scepter and Ethereal Blade, this could become even worse for Shadow Fiend if he does not have Black King Bar.
* Even though Shadow Fiend can evade all of Luna's abilities with Shadow Blade, a smart Luna will always buy Dust of Appearance to provide vision on Shadow Fiend to her and her team.

* Moon Glaives is effective at destroying Familiars and will remove one instance of Gravekeeper's Cloak upon each hit to Visage, leaving him susceptible to damage.

* Heroes with damage over time abilities can quickly eat through Gravekeeper's Cloak charges like Huskar, Jakiro and Queen of Pain.

* Untouchable won't mitigate magic damage, and a squishy Enchantress is very vulnerable to Queen of Pain's magic burst.

* Though Enchantress's Untouchable can greatly reduce Luna's attack speed, and can go through any form of Spell Immunity, she has a pitiful HP so Lucent Beam and Eclipse can kill her very quickly.
* Moon Glaives allows Luna to clear Enchantress's creeps very efficiently.
Additional:
* Enchantress has pitiful HP, even more pitiful than Luna, so Lucent Beam and Eclipse will often harass and/or kill her through her Untouchable.
* With Moon Glaives, Luna can clear Enchantress's creep wave efficiently.

* Blink allows Queen of Pain to avoid ganks and keep her distance, preventing Monkey King from building up Jingu Mastery.
* Scream of Pain and Sonic Wave will hit Monkey King when he is disguised, or on a tree.
* The large AoE and low cooldown also helps Queen of Pain hit the real Monkey King inside of Wukong's Command.

* Luna can shrug off most damage taken from Nether Ward as she only has two castable skills with average mana cost.
* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Lucent Beam's considerable range can reliably cancel Pugna's Life Drain.
* Luna is a common Black King Bar carrier, which totally nullifies Pugna's damage output.
* If Pugna uses Decrepify on himself to avoid Luna's right click, she can burst him down with Lucent Beam and Eclipse.
Additional:
* Life Drain will be always canceled by Lucent Beam if Pugna does not have Black King Bar.
* Decrepify can be suicide against Luna due to Lucent Beam and Eclipse.
* Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet have very high mana costs, she does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.

* Blink can instantly break Static Link, making it useless against her.
* Queen of Pain doesn't fully rely on her physical attack damage, so she can still fight after being hit with Static Link.

* Even though Wraith King can easily get a chance to retaliate with Reincarnation after Luna uses Eclipse against him, smart Luna can also turn Reincarnation against him by using Eclipse right after Reincarnation triggers and gets on cooldown, giving Luna an element of surprise she can use against Wraith King.
* Moon Glaives can be used to clear the waves of Wraith King's skeleton warriors summoned from Vampiric Spirit.
Additional:
* Even though Wraith King can easily get a chance to retaliate with Reincarnation after Luna uses Eclipse against him, smart Luna can also turn Reincarnation against him by using Eclipse right after Reincarnation triggers and gets on cooldown, giving Luna an element of surprise she can use against Wraith King.
* Moon Glaives can be used to clear the waves of Wraith King's skeleton warriors summoned from Vampiric Spirit.

* Even though Luna has a hard time laning against Viper due to Nethertoxin being able to disable Moon Glaives and Lunar Blessing, Luna can take out Viper once she builds either Black King Bar or Silver Edge which will allow her to attack Viper freely.
* Eclipse can often finish off Viper from early-to-mid stages of the game before he can retaliate as Corrosive Skin gives little magic resistance to him early on.
* Manta Style is an item that Luna commonly buys in most of the games, which lets her disjoint Viper Strike. Additionally, illusions from Manta Style can make Viper waste time attacking them.

* Queen of Pain can Blink to both escape and initiate onto Void Spirit.
* She is also a very common Orchid Malevolence carrier, which can prevent Void Spirit from contributing much in fights.

* Queen of Pain usually outlanes Invoker, giving her team a significant early game advantage while Invoker is still farming.
* Blink allows Queen of Pain to escape from Invoker's combo if he doesn't have disables.

* Lucent Beam interrupts Death Ward from a decent range.
* Eclipse kills Witch Doctor during Death Ward, even through Glimmer Cape.

* Blink makes it hard for Gyrocopter to pin down Queen of Pain.
* Sonic Wave is very effective at ganking Gyrocopter in the early game.

* Cold Embrace is no salvation against Lucent Beam and Eclipse.
* Moon Glaives will not hit a hero affected by Winter's Curse, making it weak against allies, but strong versus enemies.
* Luna has better night vision provided by Lunar Blessing than Winter Wyvern when affected by Arctic Burn.
Additional:
* Cold Embrace is no salvation against Lucent Beam and Eclipse.

* Lucent Beam can be used to cancel both, Tether and Relocate.
* Like with Leshrac's Diabolic Edict, Lightning Storm and Pulse Nova abilities. Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.

* If Luna can use Eclipse in anticipation, Magnus will be killed before he can even manages to cast Reverse Polarity.
* Aghanim's Scepter upgraded Eclipse is a very good counter-initiation tool against Magnus when he casts Reverse Polarity, granted as long as Luna can cast it from safe distance.

* Even though Luna is the kind of hero that Bounty Hunter can handle due to Shadow Walk rendering him safe from Eclipse, smart Luna will always buy Dust of Appearance, allowing her to provide vision on him to her team, and possibly, kill Bounty Hunter with Eclipse.
Additional:
* Even though Luna is the kind of hero that Bounty Hunter can handle due to Shadow Walk rendering him safe from Eclipse, smart Luna will always buy Dust of Appearance, allowing her to provide vision on him to her team, and possibly, kill Bounty Hunter with Eclipse.

* Although Lifestealer can avoid Eclipse with Rage and Infest, Luna's physical damage can be enough to deal with him.
* Manta Style is a common pick on Luna, which can help her dispel slows from Ghoul Frenzy and Open Wounds. In addition, Lifestealer is not good against illusions created by Manta Style.
Additional:
* Although Lifestealer can avoid Eclipse with Rage and Infest, Luna's physical damage from Moon Glaives and Lunar Blessing can be enough to deal with him.
* Manta Style is a common pick on Luna, which can help her dispel slows from Ghoul Frenzy and Open Wounds. In addition, Lifestealer is not good against illusions created by Manta Style.

* Lunar Blessing gives allies bonus damage and armor required to endure against Atrophy Aura early on.
* Eclipse can be devastating for Underlord's team when they're grouped up for Dark Rift, it can also be used to intercept arrivals with Dark Rift. And Pit of Malice does not prevent Luna to use it.
* To make things even better, Aghanim's Scepter upgraded Eclipse can finish off Underlord or any of his teammates escape attempts with Dark Rift if timed correctly.
Additional:
* Lunar Blessing gives allies bonus damage required to endure against Atrophy Aura early on.
* Eclipse can be devastating for Underlord's team when they're grouped up for Dark Rift, it can also be used to intercept arrivals with Dark Rift. And Pit of Malice does not prevent Luna from using it.
* To make things even worse, Aghanim's Scepter upgraded Eclipse can finish off Underlord or any of his teammates escape attempts with Dark Rift if timed correctly.

* Queen of Pain can easily escape Chain Frost thanks to Blink.
* His low survivability makes an easy kill for Shadow Strike, Scream of Pain & Sonic Wave.

* He's the kind of hero that likes to remain at low hp, which is perfect for Queen of Pain to burst with Sonic Wave.
* You should be able to blink away after he jumps on you with Life Break.

* Without Black King Bar, Luna will be able to cancel Enigma's Black Hole from safe distance with her Lucent Beam or with 0.25s Eclipse Lucent Ministun talent and counter-initiate with Eclipse. This can get even worse for Enigma once Luna gets Aghanim's Scepter and combines it with 0.25s Eclipse Lucent Ministun talent that will allow Luna to use Eclipse from safe distance.
* If Luna chooses to use Eclipse in anticipation right after Enigma jumps in with Blink Dagger, she will be able to kill Enigma before he even gets a chance to use Black Hole.
* Moon Glaives combined with Lunar Blessing can make a short work of Enigma's Eidolons before Luna uses Eclipse.
* Bear in mind, however, that once Enigma gets Black King Bar, Luna will be out of solutions to cancel Black Hole, and going for Abyssal Blade on Luna can be risky due to Abyssal Blade's very short cast range.

* Luna's Moon Glaives and Lunar Blessing can help her destroy Tombstone easily, and this becomes more effective if Luna is equipped with Manta Style.
* Spell Immunity of Zombies from Tombstone is a total disadvantage against Luna because Eclipse will strike only Undying, which can turn Undying's own ability against him.
* Though Undying often builds Blade Mail which can turn Luna's burst damage against her, Luna often builds Black King Bar which will allow her to attack Undying freely because Blade Mail cannot pierce spell immunity.
Additional:
* Luna's Moon Glaives and Lunar Blessing can help her destroy Tombstone easily, and this becomes more effective if Luna is equipped with Manta Style.
* Spell Immunity of Zombies from Tombstone is a total disadvantage against Luna because Eclipse will strike only Undying, which can turn Undying's own ability against him.
* Though Undying often builds Blade Mail which can turn Luna's burst damage against her, Luna often builds Black King Bar which will allow her to attack Undying freely because Blade Mail cannot pierce spell immunity.

* Guardian Angel does not offer protection from Eclipse, though it will negate damage from Moon Glaives.
* Luna's high magical damage from Lucent Beam and Eclipse can often finish allied heroes before Omniknight can save them with Purification.

* Timbersaw has a difficult time against magical and pure damage: Lina, Leshrac, Enchantress, Queen of Pain

* Heroes with teleports to escape Solar Blind and Will-O-Wisp: Phantom Assassin, Puck, Queen of Pain, Storm Spirit

* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).

* All of Queen of Pain's abilities are active, making Demonic Purge break from Aghanim's Scepter useless.
* However, Demonic Purge can help his allies kill a squishy Queen of Pain.
* Blink allows Queen of Pain to escape from Shadow Demon's abilities if he doesn't have disables.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Sonic Wave for the enemy.
* Queen of Pain usually builds Eul's Scepter of Divinity to dispel Shadow Poison and Soul Catcher and Linken's Sphere or Spell Block talent to block Disruption and Demonic Purge.

* Heroes with mobility spells (such as Queen of Pain's Blink and Clockwerk with Hookshot) can easily avoid Lil' Shredder and Mortimer Kisses.
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.

* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Jakiro, Pugna
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Jakiro, Pugna

* Heroes with considerable mobility can easily escape from a rolling Pangolier: Anti-Mage, Queen of Pain, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, moreover, if a player is familiar with how Rolling Thunder works, they can adjust their movement to avoid it entirely and of course outplay the Pangolier player.

* Moon Glaives can ignore certain abilities that either trigger on attack or give evasion under the condition that the heroes who have them are not primary targets. Examples include: Centaur Warrunner, Windranger, Phantom Assassin, Hoodwink etc.

* Moon Glaives can ignore certain abilities that either trigger on attack or give evasion under the condition that the heroes who have them are not primary targets. Examples include: Centaur Warrunner, Windranger, Phantom Assassin, Hoodwink etc.

* Queen of Pain can be a good hero for dealing with Ember Spirit with Orchid Malevolence, her pure damage nuke in Sonic Wave and a slow in Shadow Strike. However, Queen of Pain can be punished by Ember Spirit, as his Searing Chains prevents her from getting Blink off.

* Heroes that usually builds Linken's Sphere as a core item: Weaver, Medusa, Morphling, Queen of Pain, Storm Spirit

* Heroes who continue dealing damage while being stunned: Luna, Razor, Axe, Bristleback, Leshrac,

* Dark Seer's only disable is Vacuum. Though he starts off with high armor and health, he'll eventually have a hard time dealing with high mobility heroes such as Weaver or Queen of Pain.

* Heroes with mobility/escape mechanisms to dodge Ancient Apparition abilites, or to easily jump on him: Riki, Queen of Pain, Phantom Assassin, Windranger, Bounty Hunter, Spirit Breaker, Night Stalker, Storm Spirit, Juggernaut, etc.

* Heroes who have a high mobility (Queen of Pain, Storm Spirit, Slark, etc.).

* Illusion heroes like the aforementioned Phantom Lancer or Naga Siren, or heroes that tend to buy Manta Style, like Luna or Juggernaut, will give Slardar a hard time, as his damage is single-targeted.

* Luna's Lucent Beams and Eclipse will prevent Earthshaker from initiating or re-initiating.

* Blinking heroes like Anti-Mage or Queen of Pain can often chase down an injured Brewmaster after his ultimate expires.

* If carefully timed, Aghanim's Scepter upgraded Eclipse combined with 0.2s Eclipse Lucent Ministun talent can quickly finish off Terrorblade before he can get a chance to save himself with Sunder due to its high magical damage as long as Terrorblade has no Black King Bar.
* Moon Glaives allows Luna to clear Terrorblade's illusions from both, Conjure Image and Manta Style, this can be particularly advantegous for Luna if she has Manta Style. Just bear in mind, however, that Reflection can be used to turn Moon Glaives against Luna during laning phase.
* Luna very often builds Satanic and Black King Bar, which allows it either to protect herself from Sunder or nullify it's effects.
Additional:
* If carefully timed, Aghanim's Scepter upgraded Eclipse can quickly finish off Terrorblade before he can get a chance to save himself with Sunder due to its high magical damage as long as Terrorblade has no Black King Bar.
* Moon Glaives allows Luna to clear Terrorblade's illusions from both, Conjure Image and Manta Style, this can be particularly advantegous for Luna if she has Manta Style. Just bear in mind, however, that Reflection can be used to turn Moon Glaives against Luna during laning phase.
* Luna very often bulds Satanic and Black King Bar as well as it's alternative item Linken's Sphere, which allows her either to protect herself from Sunder or nullify it's effects.

* Blink allows Quen of Pain to easily escape ganking or initiating attempts with Hookshot and Power Cogs.

* Moon Glaives can easily clear Chen's creeps while Eclipse can kill Chen's allies before he can react.
Additional:
* Luna's Moon Glaives and Lunar Blessing can easily kill Chen's creeps.

* Lucent Beam allows Luna to easily cancel Freezing Field.
* Without Black King Bar protection, Lucent Beam and Eclipse can make a short work out of Crystal Maiden's abysmal health.
* Skilled Luna will always buy Dust of Appearance, allowing her team to have a vision on Crystal Maiden while invisible and during channeling Freezing Field.
* Even with Black King Bar, Luna can still inflict considerable damage on Crystal Maiden with her attacks, which get empowered with Moon Glaives and Lunar Blessing, also smart and skilled Luna will buy Abyssal Blade to cancel Freezing Field even through Black King Bar in case of emergency. And since Crystal Maiden rarely buys Linken's Sphere, this can be a very big problem for her.

* Luna often builds Black King Bar, and none of Tidehunter's spells can bypass spell immunity.
* Though Anchor Smash can weaken Luna's physical damage, it does not weaken her magical damage, which means that Lucent Beam and Eclipse deal a lot of magic damage in the early and mid-game, which can bypass Tidehunter's Kraken Shell.
Additional:
* Luna often builds Black King Bar, and none of Tidehunter's spells can bypass spell immunity.
* Though Anchor Smash can weaken Luna's physical damage, it does not weaken her magical damage, which means that Lucent Beam and Eclipse deal a lot of magic damage in the early and mid-game, which can bypass Tidehunter's Kraken Shell.

* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).

Additional:
* Moon Glaives and Lunar Blessing help Luna quickly kill Nature's Prophet's treants.
* Luna can easily cancel Teleportation with her Lucent Beam.

* Heroes with mobility spells can quickly escape from Stroke of Fate or break out of Soulbind: Anti-Mage, Queen of Pain, Morphling, Storm Spirit

* Moon Glaives can ignore certain abilities that either trigger on attack or give evasion under the condition that the heroes who have them are not primary targets. Examples include: Centaur Warrunner, Windranger, Phantom Assassin, Hoodwink etc.

* Once you farm up an Orchid Malevolence or a Scythe of Vyse, you're suddenly a lot more fearsome to elusive heroes like Storm Spirit or even that pesky Puck.

* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).

* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).

* Provided Luna is able to cast it in time, Eclipse can help win a Duel from Legion Commander.
* If Luna isn't the target, she can easily use Lucent Beam and Eclipse to win the fight for the ally.
Additional:
* A well-timed Eclipse before a Duel usually prevents Legion Commander from winning Duels, if Luna is the target.
* Meanwhile, when Luna is not a target, Eclipse and Lucent Beam can also help an ally win a Duel against Legion Commander.
* However, skilled Legion Commander players will always have a Black King Bar or Aghanim's Scepter handy since neither ability pierces through spell immunity.

* Luna's Moon Glaives will not trigger Retaliate if they hit some other target first. Also Luna commonly buys items that provide lifesteal such as Satanic, which lets her heal from the damage of Retaliate, meaning that Retaliate has little effect against her.
* Eclipse can be used to counter-initiate against Centaur Warrunner after he jumps in with Blink Dagger, and initiates with Hoof Stomp. But remember that Centaur Warrunner can resolve this problem by buying Hood of Defiance and it's upgrade Pipe of Insight to diminish its damage. Or Blade Mail to reflect the damage of the Eclipse back at Luna.
* Luna also commonly buys Black King Bar, which will allow her to protect herself from both, Centaur Warrunner's abilities (except for the Retaliate), and damage reflect from Blade Mail.
Additional:
* Luna's Moon Glaives will not trigger Retaliate if they hit some other target first. Also Luna commonly buys items that provide lifesteal such as Satanic, which lets her heal from the damage of Retaliate, meaning that Retaliate has little effect against her.
* Eclipse can be used to counter-initiate against Centaur Warrunner after he jumps in with Blink Dagger, and initiates with Hoof Stomp. But remember that Centaur Warrunner can resolve this problem by buying Hood of Defiance and it's upgrade Pipe of Insight to diminish its damage. Or Blade Mail to reflect the damage of the Eclipse back at Luna.
* Luna also commonly buys Black King Bar, which will allow her to protect herself from both, Centaur Warrunner's abilities (except for the Retaliate), and damage reflect from Blade Mail.

* With Dust of Appearance, Luna will be able to use Eclipse on invisible heroes. Be mindful that Slark is exception because he'll be able to remove the debuff with Dark Pact.

* Both Scream of Pain and Sonic Wave should hit him during his Shadow Dance.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).

* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).

* Luna can easily prevent Tinker from escaping with Boots of Travel or Rearm with Lucent Beam.
* Luna can also quickly tear Tinker to shreds with Eclipse as soon as he jumps in with Blink Dagger.