* Lone druid's bear attacks on Phoenix's Supernova Egg don't increase the hit count. Given that Lone Druid's main hero often doesn't have much farm, the Supernova Egg is less likely to get killed.

* Sand King has nothing to deal with Supernova, as none of his spells are effective.
* The damage-over-time abilities of Phoenix disable Sand King's Blink Dagger very often.

* Quill Spray will hit Sand King inside Sand Storm, damaging him and putting Sand King's Blink Dagger on cooldown, preventing him from escaping.
* Epicenter's numerous damage ticks will trigger Bristleback's passive repeatedly during teamfights.

* Lone Druid and The Spirit Bear cannot burst down Bristleback due to Bristleback
* Bristleback can easily run to Lone Druid without any hesitation, with Viscous Nasal Goo to reduce armor and slow the Spirit Bear or Lone Druid and Quill Spray can deal damage to both Lone Druid and the Spirit Bear at the same time

* Ravage, being an AoE disable, cancels Epicenter's channeling from a long range, limiting his potential to counter-initiate.
* This can be remedied, however, by first using a Black King Bar, then channel Epicenter, then finally initiate with Blink Dagger.

* Cold Embrace can protect allies from Lone Druid and the Spirit bear, who mainly deal physical damage
* Winter's Curse can turn Lone Druid and the Spirit Bear against his teammates.

* Lone Druid during True Form and the Spirit bear has high HP, meaning Spirit Siphon can be very effective against them since they deal percentage damage

* Boulder Smash will push Sand King out of Sand Storm to reveal his position or an activated Epicenter off of Earth Spirit's allies, potentially wasting his combo
* Rolling Boulder and Geomagnetic Grip allow Earth Spirit to easily stun and silence Sand King and interrupt the channeling of Epicenter, completely ruining his initiation.

* Ghost Shroud can be use both offensively to slow Lone Druid or Defensively to prevent Lone Druid and The Spirit Bear from attacking him.
* Heartstopper aura burns the Spirit bear High HP over time. Additionally, it can deal decent damage to Lone Druid during his True Form.

* Brewmaster can make the Spirit Bear a much smaller threat with Cinder Brew.
* Cyclone removes the bear from a fight so that his team can easily focus on the hero.
* While most heroes would be worn down by a Spirit Bear Radiance in the time it takes to kill Lone Druid, Brewmaster is protected in Primal Split.

* Chain Frost will bounce between Lone Druid and his bear, forcing them to separate or suffer high amounts of damage.
Additional:
* Chain Frost can deliver high amounts of damage to Lone itself and his bear if they do not separate fast from each other.

* Zeus usually stays at the back in teamfights and it is hard for Sand King to find Zeus and knock him down before Zeus deals his damage.
* All of Zeus' abilities, especially Thundergod's Wrath, disables Sand King's Blink Dagger, effectively reducing Sand King's initiation and counter-initiation potential.
* Lightning Bolt deals damage to Sand King in Sand Storm and reveals him. It also interrupts channeling of Epicenter.

* Laser blinds Lone Druid, making his attacks miss. Furthermore, a Tinker with Aghanim's Scepter is sure to blind both Lone Druid and his bear, negating his ability to root or deal physical damage.

* Morphling can ignore Spirit Bear and shorten the distance to Lone Druid with Waveform.
* Morphling can use his nukes to burst Lone Druid down, provided he is not rooted/disabled by Spirit Bear beforehand.

* Grimstroke's Soulbind will always reliably connect onto both of them if they are close together.

* Paralyzing Cask is likely to bounce between him and his bear every single time.
* Lone Druid's lack of mobility makes him vulnerable to Death Ward and Maledict.

* Burrowstrike is one of the best and easiest steals for Rubick and Sand King should be careful when playing against him - it's much better to give away Sand Storm.

* Ghostship helps your team soak up damage from Epicenter, especially if he initiates during the battle.
* Sand King can't dodge X Marks the Spot - Torrent combo by his abilities. Torrent drags him out of his Sand Storm

* Arcane Orb deals heavy damage to both Lone Druid and the Spirit Bear.
* Astral Imprisonment can prevent the Spirit Bear from attacking, which is Lone Druid's main damage output.
* Sanity's Eclipse deals heavy damage to Lone Druid.

* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom

* Riki: Smoke Screen can prevent Lone Druid from using True Form and Savage Roar, additionally it cause the spirit bear to miss on attacks which reduce the chances of getting rooted from it, with diffusal Blade, he can keep Lone Druid or the Spirit Bear inside the Smoke.

* Clinkz, Sniper, Lone Druid, Troll Warlord, Legion Commander, Wraith King and others are some of the Heroes that bases themselves on attacks with little or no spell power, suffering in the grassy hands of Overgrowth.

* Pugna: Decrepify prevent the Spirit bear from attacking or protect allies from it.

* Pugna's Nether Ward damages Sand King when he channels Epicenter, preventing him from using Blink Dagger afterward.

* Timbersaw: Lone Druid will have a hard time dealing with Timbersaw due to his tankiness and high Armor from Reactive Armor

* Reality Rift lets Chaos Knight bypass the Spirit Bear and jump onto Lone Druid.
* The Spirit Bear's lack of scaling means it dies quickly to Chaos Knight during the late-game.

* Ensnare is good vs bear.
* In teamfights, song of the siren may be used to properly set up and coordinate an attack on Lone Druid in the backline, bursting him down, allowing to completely ignore the bear.
* Druid lack innate AoE capabilities giving him no good way of dealing with illusions.