Silencer
[wiki] rating: 2.0 (winrate: 49% pickrate: 5%)Rubick
[wiki] rating: 2.0 (winrate: 46% pickrate: 16%)Omniknight
* All of Omniknight's abilities are valuable for Rubick to 
Spell Steal, and Omniknight has no throwaway ability to cover his last used spell.
Additional:
* All Omniknight's abilities are perfect to steal:
* 
Purification can heal allies as well as damage enemies under the right circumstances. It is extremely useful since Rubick has no heal of his own.
* 
Heavenly Grace gives a strength bonus, status resistance, and health regeneration, which can help an ally or Rubick survive longer.
* 
Guardian Angel can turn the tide of battle by negating all physical damage, which is especially useful if the opposing team has physical attackers.
Sand King
* Burrowstrike is one of the best and easiest steals for Rubick and Sand King should be careful when playing against him - it's much better to give away Sand Storm.
Nyx Assassin
[wiki] rating: 1.2 (winrate: 54% pickrate: 7%)Sand King
* Deals damage over time: 
Venomancer, 
Huskar, 
Ember Spirit, 
Dark Seer, 
Sand King, 
Doom
* The nature of some abilities turn them into an easy target for a turnover from Spiked Carapace:
* Slow-moving projectiles: 
Skywrath Mage, 
Tinker, 
Necrophos
* Large area-of-effect with delay or require channeling: 
Enigma, 
Crystal Maiden, 
Invoker, 
Shadow Fiend, 
Pugna, 
Keeper of the Light
* Deals damage over time: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom
Omniknight
* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: 
Lion, 
Anti-Mage, 
Nyx Assassin
Enigma
[wiki] rating: 1.0 (winrate: 55% pickrate: 8%)Omniknight
* Heroes under Guardian Angel can be still damaged from the pure damage of Black Hole and Midnight Pulse.
* Heavenly Grace will do nothing against Enigma except amplifying damage of the Midnight Pulse.
Outworld Destroyer
[wiki] rating: 1.0 (winrate: 51% pickrate: 13%)Omniknight
* 
Arcane Orb's pure damage penetrates Guardian Angel's defense.
* Outworld Destroyer's intelligence steal is also devastating to Omniknight's already low mana pool.
Luna
[wiki] rating: 1.0 (winrate: 51% pickrate: 7%)Omniknight
* Guardian Angel does not offer protection from 
Eclipse, though it will negate damage from 
Moon Glaives.
Oracle
[wiki] rating: 1.0 (winrate: 51% pickrate: 10%)Omniknight
* 
Fortune's End's AoE dispel will remove Guardian Angel.
Additional:
* With Fortune's End, Oracle can dispel Guardian Angel in an area of effect.
Monkey King
[wiki] rating: 1.0 (winrate: 50% pickrate: 16%)Omniknight
* Jingu Mastery will still add stacks even through Guardian Angel.
* Monkey King can join a fight whenever he chooses to, meaning he can simply go directly onto Omniknight.
* During the laning phase, Jingu Mastery with Boundless Strike will kill off Omniknight, while Purification is weak.
* Heavenly Grace is useless against Monkey King's ultimate and Jingu Mastery bonuses.
Tidehunter
[wiki] rating: 1.0 (winrate: 50% pickrate: 10%)Sand King
* 
Ravage, being an AoE disable, cancels Epicenter's channeling from a long range, limiting his potential to counter-initiate.
* This can be remedied, however, by first using a 
Black King Bar, then channel Epicenter, then finally initiate with 
Blink Dagger.
Invoker
[wiki] rating: 1.0 (winrate: 50% pickrate: 16%)Omniknight
* 
Tornado dispels Guardian Angel from multiple targets.
* Guardian Angel is generally useless against Invoker as he primarily relies on magical damage.
* 
EMP depletes Omniknight's already small mana pool.
* Invoker's many disables keep Omniknight's team occupied until Guardian Angel times out.
Phoenix
[wiki] rating: 1.0 (winrate: 50% pickrate: 9%)Sand King
* Sand King has nothing to deal with 
Supernova, as none of his spells are effective.
* The damage-over-time abilities of Phoenix disable Sand King's Blink Dagger very often.
Brewmaster
[wiki] rating: 1.0 (winrate: 50% pickrate: 1%)Omniknight
* 
Dispel Magic from {U:Storm} instantly removes Guardian Angel from Omniknight's allies in its radius of effect.
Earth Spirit
[wiki] rating: 1.0 (winrate: 48% pickrate: 10%)Sand King
* 
Boulder Smash will push Sand King out of Sand Storm to reveal his position or an activated Epicenter off of Earth Spirit's allies, potentially wasting his combo
* 
Rolling Boulder and 
Geomagnetic Grip allow Earth Spirit to easily stun and silence Sand King and interrupt the channeling of Epicenter, completely ruining his initiation.
Zeus
[wiki] rating: 1.0 (winrate: 46% pickrate: 8%)Sand King
* 
Zeus usually stays at the back in teamfights and it is hard for Sand King to find Zeus and knock him down before Zeus deals his damage.
* All of Zeus' abilities, especially 
Thundergod's Wrath, disables Sand King's Blink Dagger, effectively reducing Sand King's initiation and counter-initiation potential.
* 
Lightning Bolt deals damage to Sand King in Sand Storm and reveals him. It also interrupts channeling of Epicenter.
Bristleback
[wiki] rating: 1.0 (winrate: 46% pickrate: 8%)Sand King
* Quill Spray will hit Sand King inside 
Sand Storm, damaging him and putting Sand King's Blink Dagger on cooldown, preventing him from escaping.
* 
Epicenter's numerous damage ticks will trigger Bristleback's passive repeatedly during teamfights.
Snapfire
[wiki] rating: 1.0 (winrate: 46% pickrate: 5%)Omniknight
* 
Mortimer Kisses can reduce Omniknight's impact in teamfights. Omniknight's Heavenly Grace cannot purge multiple stacks of Mortimer Kisses. The damage is also magical, making Omniknight's ultimate, Guardian Angel, useless.
Ancient Apparition
[wiki] rating: 0.6 (winrate: 52% pickrate: 10%)Omniknight
* Heroes with large magical AoE damage will fare well against Omniknight: 
Lich, 
Ancient Apparition, 
Jakiro, 
Disruptor
Weaver
[wiki] rating: 0.6 (winrate: 51% pickrate: 13%)Omniknight
* Heroes that rely on slows or low-duration stuns have trouble catching Weaver: 
Omniknight, Lich.
Lion
[wiki] rating: 0.6 (winrate: 50% pickrate: 17%)Omniknight
* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin
Venomancer
[wiki] rating: 0.6 (winrate: 50% pickrate: 5%)Omniknight
* Heroes who can harass Omniknight out of lane will keep him weak in the mid game: 
Viper, Venomancer, 
Clinkz
Anti-Mage
[wiki] rating: 0.6 (winrate: 49% pickrate: 13%)Omniknight
* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin
Lich
[wiki] rating: 0.6 (winrate: 48% pickrate: 10%)Omniknight
* Heroes with large magical AoE damage will fare well against Omniknight: Lich, Ancient Apparition, Jakiro, Disruptor
Viper
[wiki] rating: 0.6 (winrate: 47% pickrate: 6%)Omniknight
* Heroes who can harass Omniknight out of lane will keep him weak in the mid game: Viper, Venomancer, Clinkz
Naga Siren
[wiki] rating: 0.4 (winrate: 54% pickrate: 2%)Omniknight
* 
Song of the Siren can be used to time out Guardian Angel, giving Naga Siren's team an easy opportunity to counter-initiate.
Additional:
* Song of the Siren will waste Guardian Angel.
* Ensnare fully works on Heavenly Graced targets. However, Ensnare is dispellable with any dispel, and so can be dispelled by Heavenly Grace.
* As an agility hero that relies on illusions, Naga Siren is one of the most natural 
Diffusal Blade carriers, the bane of every hero with a small mana pool.
Sand King
* Sand King and 
Phoenix has many tools to deal with a crowd of Heroes, which will work well against a crowd of illusions.
Enchantress
[wiki] rating: 0.4 (winrate: 46% pickrate: 1%)Omniknight
* Impetus is not blocked by Guardian Angel. A {U:Satyr Banisher} can also be controlled to dispel Guardian Angel.
Sand King
* Sand King is a strong ganker, allowing him to shut down squishy heroes in the early game: 
Phantom Assassin, Clinkz, 
Sniper, 
Enchantress,...
Doom
[wiki] rating: 0.4 (winrate: 44% pickrate: 2%)Omniknight
* 
Doom turns Omniknight into a walking creep, or completely takes out his buffed cores, also removing Guardian Angel in the process.
* Doom has access to Satyr Banisher's 
Purge, which allows him to remove Guardian Angel.
Additional:
* Doom applies a basic dispel upon cast, so it can remove Guardian Angel.
* Casting Doom on Omniknight will also prevent him from healing allies with Purification, or casting buffs like Heavenly Grace and Guardian Angel, basically turning him into a harmless creep.
Omniknight
* Heroes with the ability to heal allies, or those with good defensive abilities: 
Chen, 
Dazzle, 
Io, 
Oracle, Omniknight, 
Witch Doctor, 
Winter Wyvern, 
Abaddon, etc.
Phantom Assassin
[wiki] rating: -1.6 (winrate: 45% pickrate: 16%)Sand King
* Phantom Assassin relies on her 
Blur to stay alive, but is very vulnerable to Sand King's heavy magic damage.
* With Burrowstrike, Sand King can often catch Phantom Assassin before she can use her Black King Bar.
* Sand King can dodge 
Stifling Dagger with Sandstorm.
* Phantom Assassin has a hard time killing Sand King because of his high mobility.
Omniknight
* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: 
Sven, Phantom Assassin, 
Juggernaut, 
Dragon Knight, 
Lycan, 
Ursa, 
Troll Warlord
Additional:
* Purification easily catches Phantom Assassin when she jumps in to attack.
* Guardian Angel renders Phantom Assassin useless, as she depends entirely on physical attacks.
Sniper
[wiki] rating: -1.6 (winrate: 49% pickrate: 6%)Sand King
* Sand King is a strong ganker, allowing him to shut down squishy heroes in the early game: Phantom Assassin, Clinkz, Sniper, Enchantress,...
Omniknight
* Being mostly a physical damage dealer, Sniper's effectiveness is greatly reduced by Omniknight's Guardian Angel.
* Omniknight's 
Degen Aura allows him to slow sniper and catch him. Sniper has to then use some escape item.
* Omniknight can also protect an ally from being finished off by Assassinate by using Purification.
Chaos Knight
[wiki] rating: -1.6 (winrate: 52% pickrate: 3%)Omniknight
* 
Phantasms can be easily killed with Purification.
* Heavenly Grace dispels the stun from 
Chaos Bolt and the armor reduction from 
Reality Rift.
* Guardian Angel works well against Chaos Knight's overwhelming reliance on physical burst damage.
Additional:
* Purification heals a teammate targeted by Reality Rift and heavily damages Chaos Knight and his illusions in the process.
* Guardian Angel blocks all of Chaos Knight's damage for a duration.
Sand King
* Because of his massive AoE damage, Sand King is very effective against illusion heroes: 
Chaos Knight, 
Phantom Lancer, 
Terrorblade,...
Additional:
* Sand King's massive area damage output, particularly Epicenter, allows him to quickly take down Chaos Knight and his illusions.
* He can apply 
Caustic Finale to illusions with attacks for extra damage.
Slark
[wiki] rating: -1.4 (winrate: 48% pickrate: 13%)Sand King
* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, 
Earth Spirit, 
Faceless Void, 
Magnus, 
Mirana, 
Monkey King, 
Morphling, 
Pangolier, Phantom Assassin, Phoenix, 
Puck, 
Queen of Pain, 
Riki, Sand King, 
Spirit Breaker, 
Timbersaw, 
Tusk.
Sand King
* He has a hard time killing Sand King because of the survivability he gets from Burrowstrike and Sand Storm.
* 
Shadow Dance, which usually allows Slark to survive fights, is ineffective against Sand King's AoE damage.
Omniknight
* Slark's dependence on Pounce and close range makes him very easy to hit with Purification.
* Slark's damage, even with a high count of Essence Shift, is easily negated by Omniknight's heals and Guardian Angel.
Magnus
[wiki] rating: -1.2 (winrate: 44% pickrate: 4%)Sand King
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, 
Luna, 
Naga Siren, 
Mars, Jakiro, Venomancer, 
Elder Titan, Faceless Void, 
Rubick, Keeper of the Light, Pugna, Invoker, 
Spectre, 
Alchemist, 
Treant Protector, 
Lina, Oracle, Zeus, 
Shadow Shaman, Phoenix, 
Razor, Huskar, 
Batrider, 
Kunkka, 
Tidehunter, 
Wraith King, Sand King.
Omniknight
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King.
Dragon Knight
[wiki] rating: -1.2 (winrate: 48% pickrate: 4%)Omniknight
* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord
Sand King
* Heroes with no mobility will take some good damage from Sand King's spells: Dragon Knight, Jakiro, Pugna, 
Earthshaker,...
Ursa
[wiki] rating: -1.2 (winrate: 51% pickrate: 16%)Sand King
* Heroes that rely on slows to get kills: 
Lifestealer, 
Night Stalker, Ursa,...
Omniknight
* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord
Nature's Prophet
[wiki] rating: -1.0 (winrate: 44% pickrate: 5%)Sand King
* Sand King has many tools to deal with Nature's Prophet's treants.
* Sand King also can interrupt Teleportation with 
Burrowstrike.
Additional:
* With Caustic Finale, Sand King can easily kill the treants from 
Nature's Call.
* Burrowstrike allows Sand King to prevent Nature's Prophet from using 
Teleportation inside of his 
Sprout.
Meepo
[wiki] rating: -1.0 (winrate: 45% pickrate: 1%)Sand King
* Burrowstrike can stun multiple Meepos, making them vulnerable targets.
* Epicenter and Sand Storm's AoE damage ensures all Meepo clones get damaged, making it hard for Meepo to choose which one to flee as all are taking damage at the same rate.
* Just be aware when using Sand Storm to escape, as Meepo has good AoE damage and disables, which, as explained in the "Bad Against" section, works well against an invisible Sand King.
Ember Spirit
[wiki] rating: -1.0 (winrate: 47% pickrate: 9%)Omniknight
* The pure damage provided by Purification is a great addition for killing Ember Spirit, as well as a good way of saving teammates.
* Guardian Angel will temporarily save his allies from Sleight of Fist's physical damage, and Ember Spirit is not a hero that will get 
Orchid Malevolence to counter it.
Witch Doctor
[wiki] rating: -1.0 (winrate: 47% pickrate: 13%)Omniknight
* Guardian Angel protects allies from Death Ward's physical damage.
* Purification and Heavenly Grace will most likely save teammates from dying to Maledict.
Spectre
[wiki] rating: -1.0 (winrate: 47% pickrate: 3%)Omniknight
* Global Guardian Angel will protect his allies from Spectre's 
Haunt, both when they are alone and in teamfights.
* Purification is a major problem for melee enemies, Spectre included, since they must be next to an enemy in order to attack. The AoE damage also allows Spectre to be singled out from her illusions.
* Degen Aura will prevent Spectre from chasing Omniknight, further exacerbated by her terrible mobility outside Haunt.
Grimstroke
[wiki] rating: -1.0 (winrate: 47% pickrate: 12%)Omniknight
* Heavenly Grace dispels the stun from Ink Swell, and greatly reduces Soulbind's duration.
* Purification can turn the tables on enemies trying to get close to stun with Ink Swell.
Legion Commander
[wiki] rating: -1.0 (winrate: 47% pickrate: 11%)Omniknight
* Both Guardian Angel and Purification are perfect counters against 
Duel.
Additional:
* Purification prevents Legion Commander from killing her target, and will always hit her during Duels.
* Guardian Angel completely wastes Duel's duration, and can save an ally across the map when upgraded with 
Aghanim's Scepter.
Drow Ranger
[wiki] rating: -1.0 (winrate: 47% pickrate: 4%)Omniknight
* In team fights, Guardian Angel renders Drow Ranger's physical damage useless.
Axe
[wiki] rating: -1.0 (winrate: 47% pickrate: 8%)Omniknight
* Omniknight's healing prevents allies from dropping low enough for 
Culling Blade. However, it can still go through all his buffs.
* Axe also enjoys getting close to allied heroes in order to damage them with his 
Counter Helix, which can easily be punished by Purification.
Riki
[wiki] rating: -1.0 (winrate: 48% pickrate: 5%)Omniknight
* Riki takes a lot of damage from Purification while ganking Omniknight's allies or himself.
* Heavenly Grace instantly purges the slow from Diffusal Blade, while also providing a large amount of survivability for his victim.
* Degen Aura can hinder Riki's positioning tactics and put a heavy toll on Riki's already poor movement speed.
* Omniknight can easily save his allies by using Guardian Angel in combat.
Winter Wyvern
[wiki] rating: -1.0 (winrate: 49% pickrate: 7%)Omniknight
* Guardian Angel completely counters 
Winter's Curse if he is able to cast it.
Additional:
* Guardian Angel completely counters Winter's Curse, allowing his team to survive Winter Wyvern's initiation.
* Purification and Heavenly Grace are very useful against Arctic Burn and Splinter Blast as well.
Gyrocopter
[wiki] rating: -1.0 (winrate: 50% pickrate: 5%)Omniknight
* Guardian Angel negates most of Gyrocopter's physical АоЕ damage.
* Heavenly Grace dispels Homing Missile stun.
Templar Assassin
[wiki] rating: -1.0 (winrate: 51% pickrate: 5%)Sand King
* Sand King can quickly remove her 
Refraction with his Sand Storm.
* Once Refraction is down, she is very vulnerable to Epicenter's high magic damage.
Spirit Breaker
[wiki] rating: -1.0 (winrate: 51% pickrate: 8%)Omniknight
* In the early game, Omniknight can look like an easy target for Spirit Breaker, but with Purification and Degen Aura, what could be an opportunity could quickly turn into disaster.
* Heavenly Grace can be used to counter Charge of Darkness by minimizing the damage and lowering the stun duration with status resistance.
* Spirit Breaker's Greater Bash from all sources (Charge of Darkness or normal attacks) deals lesser damage if he is within the radius of Degen Aura.
* Due to this, Spirit Breaker's damage will always be lower when targeting Omniknight.
Ogre Magi
[wiki] rating: -1.0 (winrate: 51% pickrate: 14%)Omniknight
* Heavenly Grace reduces Fireblast stun time and dispels Ignite.
* Purification can heal damaged hero if needed.
Bloodseeker
[wiki] rating: -1.0 (winrate: 51% pickrate: 4%)Omniknight
* Guardian Angel's near invulnerability denies Bloodseeker the bonuses from Thirst, preventing him from gaining the upper hand in teamfights.
* Purification's pure damage makes it hard for Bloodseeker to pursue enemies, and prevents him from replenishing his health by finishing off enemies.
Phantom Lancer
[wiki] rating: -1.0 (winrate: 51% pickrate: 10%)Sand King
* All of Sand King's abilities deal AoE damage.
* Epicenter will usually eliminate all illusions in one cast. Phantom Lancer lacks any disables to stop the channelling.
Death Prophet
[wiki] rating: -1.0 (winrate: 51% pickrate: 10%)Omniknight
* 
Exorcism's damage is blocked by Guardian Angel.
Additional:
* Degen Aura reduces Death Prophet's movement speed, keeping her in range.
* Guardian Angel nullifies the physical damage from Exorcism.
Clockwerk
[wiki] rating: -1.0 (winrate: 52% pickrate: 7%)Omniknight
* Purification does great damage to Clockwerk when fighting an enemy inside Power Cogs.
* For the same reasons, Omniknight also makes a powerful ally for Clockwerk when the situation is reversed.
Chen
[wiki] rating: -1.0 (winrate: 52% pickrate: 0%)Sand King
* Burrowstrike and Sand Storm will deal a large amount of damage to Chen's creeps.
* Caustic Finale will quickly clear Chen's creeps at low health.
Juggernaut
[wiki] rating: -1.0 (winrate: 52% pickrate: 19%)Omniknight
* Guardian Angel completely negates all physical damage, including 
Omnislash.
Additional:
* Omnislash is blocked by Guardian Angel.
Broodmother
[wiki] rating: -1.0 (winrate: 53% pickrate: 2%)Sand King
* Caustic Finale allows Sand King to easily kill Broodmother's Spiderlings throughout the game.
* Sand King can usually catch a split pushing Broodmother with Blink Dagger and Burrowstrike.
Additional:
* Burrowstrike can be used as an escape or initiation against Broodmother.
* Sand Storm quickly kills any spiderlings caught inside if Sand King can manage to stun them.
Faceless Void
[wiki] rating: -0.6 (winrate: 41% pickrate: 3%)Omniknight
* Any hero that can nullify effects of Chronosphere: (Omniknight, Keeper of the Light with Aghanim's Scepter during daytime, Winter Wyvern), banishing him or Faceless Void (
Outworld Destroyer, 
Shadow Demon, Earth Spirit with Aghanim's Scepter) or protecting him in other ways (Dazzle, Oracle, Abaddon) can greatly limit Chronosphere's potential.
Terrorblade
[wiki] rating: -0.6 (winrate: 46% pickrate: 4%)Sand King
* Because of his massive AoE damage, Sand King is very effective against illusion heroes: Chaos Knight, Phantom Lancer, Terrorblade,...
Mars
[wiki] rating: -0.6 (winrate: 48% pickrate: 16%)Omniknight
* Heroes that can save their allies can be a big problem for Mars: Dazzle, Omniknight.
Earthshaker
[wiki] rating: -0.6 (winrate: 49% pickrate: 12%)Sand King
* Heroes with no mobility will take some good damage from Sand King's spells: Dragon Knight, Jakiro, Pugna, Earthshaker,...
Necrophos
[wiki] rating: -0.6 (winrate: 50% pickrate: 3%)Omniknight
* Heroes who possess abilities that can save targets from being killed by Reaper's Scythe: Abaddon, 
Bane, Outworld Destroyer, Shadow Demon, Omniknight, etc.
Puck
[wiki] rating: -0.6 (winrate: 52% pickrate: 17%)Omniknight
* Heroes with spell immunity or pseudo-blinks which provide invulnerability: Lifestealer, Juggernaut, Omniknight, Huskar , and Tusk have spells which allow them to easily escape Dream Coil.
Shadow Shaman
[wiki] rating: -0.6 (winrate: 52% pickrate: 16%)Omniknight
* Omniknight can dispel Hex or Shackles with Heavenly Grace. He can also heal teammates which you disabled. The same goes to Abaddon's 
Aphotic Shield .
Troll Warlord
[wiki] rating: -0.6 (winrate: 52% pickrate: 12%)Omniknight
* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord
Bane
[wiki] rating: -0.6 (winrate: 54% pickrate: 3%)Omniknight
* Heroes with dispels can dispel Bane's disables from their allies: Oracle, 
Legion Commander, Omniknight
Bounty Hunter
[wiki] rating: -0.6 (winrate: 54% pickrate: 10%)Omniknight
* Omniknight with Heavenly Grace
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and 
Borrowed Time
* Huskar with 
Life Break
* Juggernaut with 
Blade Fury
* Legion Commander with 
Press the Attack
* Lifestealer with 
Rage and 
Infest
* Naga Siren with 
Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and 
False Promise
* Phantom Lancer with 
Doppelganger
* 
Slark with 
Dark Pact
* Ursa with 
Enrage
* 
Weaver with 
Time Lapse
* Tidehunter with 
Kraken Shell when damage received reaches the threshold.
Lycan
[wiki] rating: -0.6 (winrate: 54% pickrate: 3%)Omniknight
* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord
Additional:
* Guardian Angel completely negates all of Lycan's damage since Lycan mainly deals physical damage.
* Purification can also be a problem for Lycan, as Purification deals damage around the target, which poses a problem for him and his summons.
Disruptor
[wiki] rating: -0.4 (winrate: 49% pickrate: 9%)Omniknight
* Heroes with large magical AoE damage will fare well against Omniknight: Lich, Ancient Apparition, Jakiro, Disruptor
Omniknight
* Purification allows Omniknight to keep a hero trapped in the Static Storm alive.
Sven
[wiki] rating: 0.0 (winrate: 43% pickrate: 1%)Omniknight
* Although Sven relies often on physical damage, a 
Aghanim's Shard-upgraded 
Storm Hammer can dispel Guardian Angel with its wide radius.
Omniknight
* Purification can heal allies while dealing pure damage to Sven.
* Heavenly Grace can remove Storm Hammer's debuff immediately or make it a very mediocre stun.
* Guardian Angel negate's Sven's massive damage during God's Strength.
Kunkka
[wiki] rating: 0.0 (winrate: 44% pickrate: 3%)Sand King
* Ghostship helps your team soak up damage from Epicenter, especially if he initiates during the battle.
* Sand King can't dodge X Marks the Spot - Torrent combo by his abilities. Torrent drags him out of his Sand Storm
Omniknight
* Guardian Angel makes allies immune to all physical damage, effectively causing Tidebringer to do no damage.
* Purification is a powerful, pure damaging heal that can save Omniknight's allies after Kunkka's large damage.
Shadow Demon
[wiki] rating: 0.0 (winrate: 47% pickrate: 2%)Omniknight
* Heroes that can purge buffs can dispel Guardian Angel: Invoker, Shadow Demon, Oracle.
Additional:
* Demonic Purge can dispel Guardian Angel on the key target during combat, allow your allies to finish them.
Omniknight
* Omniknight: An undispellable Heavenly Grace can easily save a victim of Shadow Demon.
Lifestealer
[wiki] rating: 0.0 (winrate: 48% pickrate: 5%)Sand King
* Lifestealer's Rage negates Sand King's spells which do magical damage.
Sand King
* Heroes that rely on slows to get kills: Lifestealer, Night Stalker, Ursa,...
Jakiro
[wiki] rating: 0.0 (winrate: 50% pickrate: 9%)Omniknight
* Heroes with large magical AoE damage will fare well against Omniknight: Lich, Ancient Apparition, Jakiro, Disruptor
Sand King
* Heroes with no mobility will take some good damage from Sand King's spells: Dragon Knight, Jakiro, Pugna, Earthshaker,...
Night Stalker
[wiki] rating: 0.0 (winrate: 52% pickrate: 5%)Omniknight
* Heroes that have a weak laning stage: Spectre, Nyx Assassin, 
Clockwerk, Spirit Breaker, Omniknight, 
Pudge.
Sand King
* Heroes that rely on slows to get kills: Lifestealer, Night Stalker, Ursa,...
Pugna
[wiki] rating: 0.0 (winrate: 53% pickrate: 4%)Sand King
* Pugna's 
Nether Ward damages Sand King when he channels Epicenter, preventing him from using Blink Dagger afterward.
Sand King
* Heroes with no mobility will take some good damage from Sand King's spells: Dragon Knight, Jakiro, Pugna, Earthshaker,...
Clinkz
[wiki] rating: 0.0 (winrate: 53% pickrate: 4%)Omniknight
* Heroes who can harass Omniknight out of lane will keep him weak in the mid game: Viper, Venomancer, Clinkz
Sand King
* Sand King is a strong ganker, allowing him to shut down squishy heroes in the early game: Phantom Assassin, Clinkz, Sniper, Enchantress,...
Sand King
* Both
Arcane Curse and 
Last Word punishes casters with spammable spells such as Sand King.
Intelligence Steal reduces Sand King's mana pool even more.
Global Silence silences Sand King, effectively reducing Sand King's initiation and counter-initiation potential. It can also interrupt channeling of Epicenter.
* As a strength caster,
*
Omniknight
*
Global Silence takes Omniknight out of the fight completely.
Glaives of Wisdom are a great harass vs Omniknight during the laning stages of the game, since it doesn't aggro creeps & ignores his high base armor. It deals pure damage, which means it can also go through Guardian Angel.
*
* Silencer's intelligence steal can also cause Omniknight to falter in the early phases as it reduces his ability to use his spells.