* Morphling's naturally high armor thanks to his high agility makes it hard for Phantom Assassin to take him down with Coup de Grace.
* Phantom Assassin is vulnerable to magical damage, falling easily to Adaptive Strike + Ethereal Blade combo.
Additional:
* Morphling's high armor serves as a direct counter to Phantom Assassin, causing her attacks to do far less damage. She is also very vulnerable to burst damage, and can be brought down quickly using his Ethereal Blade and Adaptive Strike combo.

* Waveform allows Morphling to escape from Mass Serpent Ward
* Morphling can interrupt Shadow Shaman while he is shackling an ally with Adaptive Strike (Strength).
* With Ethereal Blade Morphling can quickly burst him down before he even has a chance to react.

* Phantom Assassin's single target abilities make her very helpless against swarms of spiderlings.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Aside from Spin Web, Incapacitating Bite can cripple her due to being reliant on physical attacks and critical strikes.
Additional:
* Phantom Assassin's single target abilities make her very helpless against swarms of Spiderlings.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Incapacitating Bite cripples her due to reliant on physical attacks.

* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.

* Mirana can disturb your channeling even if you are under the effect of invisibility thanks to Sacred Arrow.
* Mirana armed with an Aghanim's Scepter is known to be able to quickly burst down heroes - especially supports. Together with Ethereal Blade the bullying can continue for the whole match.

* Ethereal state disarms the target and makes them more vulnerable to magic damage, both of which Phantom Assassin despises. Especially Pugna and any hero that is wielding Ethereal Blade, such as Mirana, Nyx Assassin or Morphling.

* Dragon Knight can simply tank and destroy all Shadow Shaman's Serpent Wards.

* Heroes that rely on physical damage are ineffective against Dragon Knight due to his high armor: Phantom Assassin,Bloodseeker, Lifestealer, Troll Warlord

Additional:
* High armor thanks to Dragon Blood makes it difficult for Phantom Assassin to burst down Dragon Knight, as she deals 100% physical damage.
* Dragon Tail stuns Phantom Assassin as soon as she initiates, preventing her from gaining bonus attack speed.
* Dragon Knight is one of the few heroes who can safely solo lane against Phantom Assassin alongside a support.

* Phantom Strike's extra attack speed causes Phantom Assassin to proc Counter Helix more often. Using it on Axe also makes Phantom Assassin an easy target for a counter-initiation with Berserker's Call and Blade Mail.
* Most of Axe's abilities pierce Black King Bar, allowing him to lock down Phantom Assassin at any time.
* Berserker's Call greatly reduces Phantom Assassin's ability to crit hard against Axe, and may cause her to kill herself when used with Blade Mail.
Additional:
* Jumping in with Phantom Strike makes Phantom Assassin an exceptionally easy target for Berserker's Call.
* The bonus attack speed from Phantom Strike also means that Phantom Assassin will proc Counter Helix numerous times.
* Black King Bar is generally useless against Axe's abilities and item build, as Black King Bar doesn't prevent Axe from finishing Phantom Assassin off with Culling Blade. It also doesn't work against Berserker's Call and Counter Helix.
* Blade Mail is an item that Axe purchases every game, and it can be used to turn Phantom Assassin's critical strikes against herself. The situation becomes even worse if she's affected by Berserker's Call, as she has no way to stop attacking.

* Pudge, Legion Commander and Axe will make the match a living hell for you, since they are known for surprise attacks from the fog and quickly killing low HP heroes. They can also interrupt your channeling, Legion being especially problematic, as she can use Press the Attack on an ally who is hexed as well.

* Slark's Pounce allows him to close the gap on Phantom Assassin and prevent her from escaping with Phantom Strike.
* As a hero who always goes for the Silver Edge and Abyssal Blade Slark can use it to disable Phantom Assassin and her Blur and Coup de Grace, drastically reducing her damage output and ability to evade attacks, and also preventing her from acting.
* Phantom Assassin's Coup de Grace requires Random Number Generation in order to proc, which gives Slark more than enough time to escape and recover himself.

* Nyx Assassin, Bounty Hunter and Slark can all sneak up and kill you, Nyx being particularly deadly. Watch Slark carefully, as he can break either (but not both unless you are making a mistake) of your disables, with Dark Pact and leap out of a serpent ward ring. These heroes, however, rely heavily on escape and are themselves not very durable and none of them can survive a full lockdown with Mass Serpent Ward. Having Sentry Wards can turn you from prey to predator.

* Nyx Assassin, Bounty Hunter and Slark can all sneak up and kill you, Nyx being particularly deadly. Watch Slark carefully, as he can break either (but not both unless you are making a mistake) of your disables, with Dark Pact and leap out of a serpent ward ring. These heroes, however, rely heavily on escape and are themselves not very durable and none of them can survive a full lockdown with Mass Serpent Ward. Having Sentry Wards can turn you from prey to predator.

* Ethereal state disarms the target and makes them more vulnerable to magic damage, both of which Phantom Assassin despises. Especially Pugna and any hero that is wielding Ethereal Blade, such as Mirana, Nyx Assassin or Morphling.

* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them: Broodmother, Phantom Lancer, Chaos Knight.

* Single-target disablers will have difficulty locking down a Chaos Knight with Phantasm active: Bane, Beastmaster, Bloodseeker, Clockwerk, Doom, Shadow Shaman.

* With 4 active abilities, Shadow Shaman is weak against silencing foes such as silencer, Drow Ranger and Death Prophet.

* In early to mid stage, Silence is also a great way to counter escape oriented heroes such as Anti-Mage, Queen of Pain, and Phantom Assassin to prevent them from escaping, provided that they don't have any basic dispels.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Sven, Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

Additional:
* Purification easily catches Phantom Assassin when she jumps in to attack.
* Guardian Angel renders Phantom Assassin useless, as she depends entirely on physical attacks.

* Omniknight can dispel Hex or Shackles with Heavenly Grace. He can also heal teammates which you disabled. The same goes to Abaddon's Aphotic Shield .

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge.

* Pudge, Legion Commander and Axe will make the match a living hell for you, since they are known for surprise attacks from the fog and quickly killing low HP heroes. They can also interrupt your channeling, Legion being especially problematic, as she can use Press the Attack on an ally who is hexed as well.

* Reincarnation allows Wraith King to survive Shadow Shaman's initial chain of disables and Serpent Ward attacks.
* Short cooldown of Wraithfire Blast is ideal for interrupting Shackles.

* Static Link can lower the damage output from Coup de Grace procs, hindering Phantom Assassin's main source of damage.
* Eye of the Storm strikes cannot be evaded by Blur.
* Both Static Link and Eye of the Storm pierces spell immunity, as Phantom Assassin is often reliant on Black King Bar.
Additional:
* Static Link greatly lowers the damage output from Coup de Grace, hindering Phantom Assassin's main source of scaling.
* Eye of the Storm strikes cannot be evaded by Blur.

* Puck relies mainly on magical burst damage, which Phantom Assassin is most vulnerable against.
* Phase Shift and Illusory Orb disjoint Stifling Dagger, also allowing to kite Phantom Assassin.
* Dream Coil will stun Phantom Assassin if she uses Phantom Strike to blink away.

* Phantom Assassin relies on her Blur to stay alive, but is very vulnerable to Sand King's heavy magic damage.
* With Burrowstrike, Sand King can often catch Phantom Assassin before she can use her Black King Bar.
* Sand King can dodge Stifling Dagger with Sandstorm.
* Phantom Assassin has a hard time killing Sand King because of his high mobility.

* Overgrowth prevents Phantom Assassin from using Blink Strike even through her spell immunity.
* Living Armor reduces Phantom Assassin's physical damage whenever she attempts to gank an allied hero.

* Due to their high attack speed, Summon Familiars will destroy Mass Serpent Ward quickly, granting Visage a massive amount of gold.
Additional:
* Due to their high attack speed, Visage's Summon Familiars will destroy Mass Serpent Ward quickly, granting Visage massive amount of gold.

* Enfeeble greatly reduces Phantom Assassin's burst damage.
* Nightmare and Fiend's Grip can ground Phantom Assassin, who normally blinks around with Phantom Strike, and stop her from outputting damage, even with Black King Bar.
* Phantom Assassin's low health pool early on makes her susceptible to Brain Sap and Fiend's Grip's heavy nuke damage.
Additional:
* Enfeeble greatly reduces Phantom Assassin's damage output, crippling her damage with Coup de Grace.
* Brain Sap's deals high magical damage against Phantom Assassin in the early game. When upgraded with Aghanim's Scepter, it can pierce spell immunity.
* Fiend's Grip can disable Phantom Assassin, even through spell immunity.

* While her Phantom Strike does give limited extra attack speed, she cannot use the ability against the Phoenix Sun, and while her Blur may protect her from attacks, Phoenix's strong magical DPS burns away her small health pool quickly, and the attack speed slow makes her unable to fight back (provided she has no source of spell immunity).
Additional:
* Fire Spirits applies a severe attack speed slow, severely hindering Phantom Assassin's damage output. While Phantom Strike may be able to slightly remedy the problem, Phoenix' magical and pure damage output completely ignore Blur's evasion, resulting in severe damage to her low health pool.

* Troll Warlord can build a Silver Edge or a Monkey King Bar to completely ignore Blur.
* Whirling Axes (Melee) provides a 60% miss chance, making a Coup de Grace critical strike very hard to land.
* Battle Trance negates Coup de Grace, preventing Troll Warlord from dying to her critical hits.
Additional:
* Whirling Axes (Melee) makes it hard to land a Coup de Grace.
* Troll Warlord often buys Silver Edge and Monkey King Bar, the items that greatly counters Phantom Assassin.
* Battle Trance completely negates Phantom Assassin's large damage output, preventing Troll Warlord from dying easily. The lifesteal also allows Troll Warlord to restore much of his health.

* Shadow Shaman has no effective burst damage, thus Chen has a lot of time to save an ally with his creeps or Hand of God from a gank.
* Chen can use {U:Centaur Conqueror} or {U:Mud Golem} to interrupt Shadow shaman's Shackles channeling
* Mass Serpent Ward can be easily teared down by Chen's creep army

* Phantom Assassin's Blur will be useless if Windranger managed to get Monkey King Bar or Bloodthorn, and other than Stifling Dagger, Phantom Assassin has no abilities that can bypass Windrun.
* Focus Fire can still deal considerable damage despite Blur's evasion due to the increased attack speed.

* Despite her high mobility, Hex or Earth Spike can lock Phantom Assassin down and make her vulnerable.
* Although she has high evasion through Blur, Phantom Assassin has a rather low health pool, making her weak to Lion's magical burst.
Additional:
* Hex and Earth Spike's fast cast animations easily catches Phantom Assassin when she jumps in to attack.
* Finger of Death often ends Phantom Assassin before she can do anything in the early to mid game.

* Retaliate deals damage to Phantom Assassin for every attack and Stifling Dagger thrown at Centaur.
* Blur cannot evade Double Edge.
Additional:
* Retaliate turns Phantom Assassin's attacks against herself, as he deals damage with every hit taken, and his big health pool makes sure that a lot of hits will be needed.
* If Centaur Warrunner gets the jump on Phantom Assassin first, she will be unable to activate Black King Bar and might be burst down with the help of his Double Edge.
* Stampede can save an ally under attack by Phantom Assassin, offsetting the slow from Stifling Dagger. If he owns an Aghanim's Scepter, he can prevent a low-health ally from being killed in one crit.

* Phantom Assassin's high physical damage is greatly reduced by Bulwark.
* God's Rebuke has true strike, ignoring the evasion from Blur.

* Sharpshooter breaks Blur and Coup de Grace especially with the level 25 talent.
* Because Phantom Assassin is often reliant on critical strikes, Hoodwink can have enough time to simply move near a tree and escape.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge.

* Omniknight can dispel Hex or Shackles with Heavenly Grace. He can also heal teammates which you disabled. The same goes to Abaddon's Aphotic Shield .

* Nyx Assassin, Bounty Hunter and Slark can all sneak up and kill you, Nyx being particularly deadly. Watch Slark carefully, as he can break either (but not both unless you are making a mistake) of your disables, with Dark Pact and leap out of a serpent ward ring. These heroes, however, rely heavily on escape and are themselves not very durable and none of them can survive a full lockdown with Mass Serpent Ward. Having Sentry Wards can turn you from prey to predator.

* Arc Warden with his Magnetic Field will protect allies from Mass Serpent Ward.

* Many physical-only single-target heroes like Lifestealer, Sven, Wraith King, Phantom Assassin etc.

* Ethereal state disarms the target and makes them more vulnerable to magic damage, both of which Phantom Assassin despises. Especially Pugna and any hero that is wielding Ethereal Blade, such as Mirana, Nyx Assassin or Morphling.

* Fate's Edict cripples many heroes who rely on attacks, such as Phantom Assassin, Sven, or Enchantress, without a dispel or a Black King Bar.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Heroes with magical burst damage can often kill Phantom Assassin before she gets to do much: Necrophos, Nyx Assassin, Gyrocopter.

* Heroes with no AoE abilities will struggle against Phantom Lancer: Clinkz, Phantom Assassin, Broodmother

* Heroes who rely on physical damage will suffer from Laser: Phantom Assassin, Wraith King, Huskar.

Additional:
* The blind from Laser can render Phantom Assassin useless if she is not protected by Black King Bar.
* Tinker is a natural Scythe of Vyse carrier and can permanently disable Phantom Assassin, not giving her chance to activate Black King Bar if she has it.

* Heroes with magical burst damage can often kill Phantom Assassin before she gets to do much: Necrophos, Nyx Assassin, Gyrocopter.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Black King Bar is useless, since all of the Spectre's abilities go through spell immunity,
* Phantom Assassin's Blur cannot evade Desolate because its damage is a separate damage instance and is applied before the attack hits.
* Spectre's high durability provided by Dispersion and damage block items makes her one of the hardest carries to take down.
Additional:
* Dispersion makes it hard for Phantom Assassin to burst down Spectre while also reflecting back Phantom Assassin's high burst damage against herself.
* Desolate ignores the evasion from Blur.
* Black King Bar is useless against Spectre as all of her skills pierce spell immunity.

* Spectre's entire ability set is designed to get to and destroy heroes that stay in the backlines, both carries (like the aforementioned Drow Ranger and Sniper) and supports (like Dazzle and Shadow Shaman).

* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Arcane Bolt's long range and low cooldowns allows Skywrath Mage to severely harass Phantom Assassin in lane.
* Ancient Seal prevents Phantom Assassin from escaping or engaging with Phantom Strike.
* Mystic Flare's heavy magical damage nukes Phantom Assassin down quickly during the early to mid game.

* Heroes that are squishy by nature are an easy target for Spirit Breaker: Sniper, Drow Ranger, Shadow Shaman

* Heroes that rely on escapes to stay alive can be caught and locked down for a long time: Queen of Pain, Phantom Assassin