* As Tinker relies heavily on his spells to be effective, Last Word and Global Silence will render him largely useless.
* Arcane Curse effectively prevents Tinker from casting spells during its duration, as he will otherwise suffer heavy damage.
* Glaives of Wisdom deal pure damage, which make quick work of fragile heroes like Tinker.
Additional:
* Silencer can stop Rearm, preventing Tinker from spamming his abilities/items or escaping.

* Pounce prevents Tinker from blinking away.
* Slark frequently builds Shadow Blade, which allows him to approach Tinker unnoticed. Since Tinker's farming usually covers a significant amount of area on the map, Sentry Wards may not be cost effective.
* Shadow Dance allows Slark to detect both common and unusual wards. Eliminating common ward causes Tinker trouble farming many lanes if he does not know who may be waiting to jump on him. Slark is also uniquely able to identify some of the less common wards used by Tinker, such as those placed on the cliffs at map edges which Tinker uses to give him vision over the trees he uses to hide in.
* Slark's extremely high move speed from Shadow Dance, potentially stacked with Shadow Blade, allows him to easily follow Tinker between lanes, especially if Tinker has pushed the lanes out.
* Dark Pact dispels Laser's blind.

* Medusa cannot chase Slark in any way and has no disable beyond her ultimate, making her unable to stop him getting away and regenerating before coming back to finish her off.
* Essence Shift removes 1 of every attribute, lowering Medusa's mana pool's cap and leaving her much more vulnerable in prolonged fights.
Additional:
* Medusa is especially vulnerable to Essence Shift, as both strength and intelligence contribute to her effective HP, while agility contributes to her damage.
* Dark Pact when timed right can be used to dispel Stone Gaze right after it petrifies Slark, allowing him to keep attacking Medusa throughout the duration.

* Silencer burns easily through her effective hp from Mana Shield, by taking away her int.
* Arcane Curse punishes her repeatedly casting Mystic Snake to keep her mana pool high. Can force her to use Manta Style before he has casted Global Silence and Medusa usually does not want to build Black King Bar.

* While many of Silencer's spells are a great steal for Rubick, Silencer effectively neuters Rubick's excellent counter-initiation potential thanks to Global Silence.
* Rubick's relatively low intelligence for such a heavy caster means that losing Intelligence to Intelligence Steal will make your mana pool even smaller.

* Pounce and Dark Pact together with some attacks can gank Rubick down quickly. Rubick can seldom retaliate because of the strong dispel of Dark Pact. What is more, Rubick is the type of squishy support that Slark exactly wants to gank.
* Though Shadow Dance is a great spell to steal, Slark's untargetable nature and his low cooldown spells prevents Rubick from stealing it.
* Slark usually builds Diffusal Blade which can prevent Rubick to cast his abilities from Spell Steal.

* Upheaval does not interrupt Slark too much, as he can just Pounce out of the area.
* Fatal Bonds and Shadow Word can be dispelled by Dark Pact.

* Because Warlock's abilities are all active abilities, Silencer can make his impact minimal.
* Arcane Curse prevents Warlock from using his abilities without taking 56/84/112/140 damage, and slowed by 9%/12%/15%/18%.
* Last Word can prevent Warlock from casting his combo.
* Global Silence can nullify Warlock's impact in fights and prevent him from getting any spells off.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Silencer will most likely disrupt an initiation with his ultimate, Global Silence, prevent escape with his Last Word, and if Phoenix happens to die to him (or near him) enough times, he would sap enough of Phoenix's much needed Intelligence to make him a stronger foe and Phoenix with less mana than it already had.

* Enigma is fragile, and lacks escapes, being dependent on Blink Dagger for mobility. Ganking Heroes or Heroes with burst damage will likely kill him before he can do anything. Such Heroes include: Lina, Lion, Puck, Slark, Nyx Assassin, etc.

* Silencer can easily ruin Enigma's initiation, as Global Silence cancels Black Hole, even through Black King Bar and Linken's Sphere.
Additional:
* Last Word can be cast from a long range to prevent Enigma's potential initiation.
* Global Silence can interrupt Enigma's Black Hole channeling through Black King Bar and Linken's Sphere.

* If Slark sees the Sacred Arrow before it hits him, he can use Dark Pact to remove it a moment later.
* Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's Aghanim's Scepter​ combo with Shadow Dance.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Arcane Curse discourages Lina from using her abilities, preventing her from building up Fiery Soul stacks.
* Last Word and Global Silence are great against Lina for the same reason, as well as interrupting her combos and preventing her from casting spells.

* Dark Pact can be cast during the cast animation of Light Strike Array and dispel its stun.
* Pounce allows Slark to close the gap to Lina.
* Shadow Dance prevents Lina from killing Slark with her Laguna Blade when his HP gets low.

* Pounce's leash prevents Storm Spirit from using Ball Lightning, making it hard for Storm Spirit to escape a gank from Slark.
* Dark Pact can dispel Orchid Malevolence's Soul Burn.

* Silencer's Intelligence Steal can reduce Storm Spirit's damage output if he gets some kills on laning phase.
* Last Word and Global Silence will make Storm Spirit an easy target.
* Global Silence can be used to block Storm Spirit from connecting abilities after a Ball Lightning on his targets.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Heroes with silencing abilities that are not blocked by Linken's Sphere, like Puck's Waning Rift, Death Prophet's Silence or Silencer's Global Silence.

* With 4 active abilities, Shadow Shaman is weak against silencing foes such as silencer, Drow Ranger and Death Prophet.

* Nyx Assassin, Bounty Hunter and Slark can all sneak up and kill you, Nyx being particularly deadly. Watch Slark carefully, as he can break either (but not both unless you are making a mistake) of your disables, with Dark Pact and leap out of a serpent ward ring. These heroes, however, rely heavily on escape and are themselves not very durable and none of them can survive a full lockdown with Mass Serpent Ward. Having Sentry Wards can turn you from prey to predator.

* Arcane Curse stacks every time Bristleback uses an ability, forcing him to stop spamming his abilities, or take heavy health degeneration.
* Glaives of Wisdom's pure damage cuts through Bristleback's tanky items. also steals intelligence both permanently and temporarily and cause mana issues for Bristleback
* Last Word and Global Silence stops Bristleback from using his abilities altogether.
Additional:
* Glaives of Wisdom deals pure damage, therefore it is not reduced by Bristleback.
* Bristleback will not be able to cast Viscous Nasal Goo or Quill Spray while silenced, effectively blocking a major part of the hero's damage and preventing Warpath charges from stacking.
* Arcane Curse slows Bristleback down and lasts longer the more abilities he uses. On the other hand, if he doesn't use any abilitiess, he will begin to lose Warpath charges.

* Arcane Curse punishes Grimstroke for spamming Stroke of Fate.
* Global Silence takes Grimstroke out of team fights entirely.

* Dark Pact can dispel Flaming Lasso if is used in anticipation, but a Blink initiation from fog can catch the Slark off guard.
* Slark can also take off any Sticky Napalm stacks with Dark Pact in lane.

* Global Silence and Last Word can prevent Ember Spirit from casting Activate Fire Remnant to escape.
* Glaives of Wisdom also provide high pure damage that is not negated by Flame Guard.
* Arcane Curse is also a potent harassing tool in the laning stage as its cooldown is lower than Flame Guard's.

* Shadow Demon's main source of damage is his low cooldown, high damage spells - meaning Last Word and Global Silence will pretty much take him out of the game for the duration.
* Shadow Demon likes to spam his abilities, which makes him vulnerable to Arcane Curse.
* If Shadow Demon dies near Silencer, he will lose intelligence, reducing his mana pool, mana regen and attack damage. Furthermore, if the game is long and Shadow Demon dies often, the intelligence losses will also reduce his spell damage.

* Heroes who can dispel will be able to remove Shadow Poison before Shadow Demon can build up a big stack, or remove Soul Catcher's debuff to instantly bring the health of affected heroes back to a considerable amount: Abaddon, Slark, Legion Commander, Oracle.

* Kunkka relies on his powerful AOE spells to turn the tides of teamfights. He cannot use them while silenced.
* Last Word can mess up Kunkka's ability synergy, silencing him in the middle of his strong combo.
* Global Silence can disable Kunkka's spell casting from anywhere on the map, even if Kunkka is spell immune at the time.

* Dark Pact can be used to remove Open Wounds.
* Shadow Dance allows Slark to attack Lifestealer for its duration without any way for Lifestealer to fight back.
* Slark commonly buys a Silver Edge, which can break Lifestealer's Feast, severely diminishing his damage output and lifesteal.

* Like any hero with a channeled spell, Last Word is a counter to it.
* Global Silence goes through spell immunity and prevents Witch Doctor from casting his spells.

* Dark Pact dispels Dismember if timed perfectly.
* Pudge's low attack speed and poor agility can be lowered even further by Essence Shift.
* Shadow Dance grants Slark invisibility and a high degree of mobility, which can make Slark a difficult target to hook and also protects him from Pudge's Dismember (including allies with an Aghanim's Scepter).

* Lion is extremely dependent on his abilities. Silences like Silencer's Last Word, magic resistance like Oracle's Fate's Edict, and dispels like Legion Commander's Press the Attack all make his abilities less effective.

* Pounce allows Slark to close in on Lion and prevent him from escaping.
* Lion's fragile health pool makes him easy prey for Slark's high burst damage through Pounce, Dark Pact and right-clicks.
* Shadow Dance prevents Lion from casting Hex, Mana Drain, or Finger of Death on Slark.
* Dark Pact allows Slark to dispel any of Lion's disables.

* Dark Pact easily purges away both slow and disarm effect from Lucky Shot.
* With Pounce now apply leash to the target, Pangolier is helpless against Slark since both his Swashbuckle and Rolling Thunder will be disabled. Pounce also help Slark to easily escape from Rolling Thunder.

* Global Silence stops Snapfire's Mortimer Kisses.
* Last Word can prevent Snapfire from casting additional spells.

* Arctic Burn and Splinter Blast debuffs are dispellable with Dark Pact. Arctic Burn is also no escape against Pounce.
* Cold Embrace just gives Slark free Essence Shift stacks. He also relies mostly on magic damage early in the game.

* Pounce's root prevents Earth Spirit from using Rolling Boulder to escape, making it easier for Slark to shut him down especially in the laning phase.

* Invoker is heavily dependent on his spells, making him useless during Global Silence, as well as interrupting Invoker during his combo.
* Arcane Curse is particularly deadly, because Invoker will continuously lose health if he keeps invoking and casting new spells.
* Last Word will silence Invoker when he casts Invoke, interrupting his combo.

* Pounce can easily break Static Link, making it less powerful against him.
* Slark is one of the few heroes who can man fight a Razor, because of Essence Shift.
* Shadow Dance can prevent Razor from killing him and may provide an opportunity to kill Razor due to it preventing Razor from attacking Slark.

* Dark Pact dispels debuffs from Gush, Anchor Smash and even Ravage if timed correctly.
* Kraken Shell cannot restore attributes stolen by Essence Shift or dispel the leash if he gets Pounced.

* Pugna is very reliant on his abilities for damage. (Just be careful around the Nether Ward)

* Shadow Dance allows Slark to not be targeted by Unstable Concoction, making Alchemist stun himself and making himself vulnerable to the enemy.
* Dark Pact also allows him to just purge off the stun if timed correctly.
* Essence Shift will steal stats over long durations at a time should Alchemist lack the damage to kill Slark.

* Dark Pact dispels Ignite's slow and Fireblast's stun.
* Shadow Dance allows Slark to regenerate HP, even when he is affected by Ignite and Fireblast.

* Last Word and Arcane Curse have the range to hit Dark Willow beyond Bramble Maze.
* Global Silence renders Dark Willow useless in teamfights.

* Arcane Curse can effectively discourage Undying from casting his spammable abilities in a team fight, as Undying will have to suffer more damage and the slow due to the penalty duration of Arcane Curse.
* Last Word and Global Silence are able to silence Undying for up to 6 seconds, preventing Undying from gaining strength and healing his ally or himself.

* Pounce prevents Anti-Mage from using Blink, and lets him disengage from Anti-Mage if needed.
* Essence Shift allows Slark to permanently steal agility from Anti-Mage.
* Shadow Dance stops Anti-Mage from being able to fight back in a slippery situation.

* Heroes with abilities or items that can silence or disable Anti-Mage for long periods of time will prevent him from Blinking away: Silencer, Shadow Shaman, Death Prophet, Clinkz, Riki, Broodmother, Skywrath Mage, Puck

* Dark Pact can dispel Venomous Gale and Poison Sting.
* Shadow Dance allows Slark heightened regeneration when out of vision making DoTs effects less threatening.

* Arcane Curse punishes Necrophos if tries to spam Death Pulse, increasing the duration of the slow and damage taken over time.
* Last Word heavily damages Necrophos and also silence him for a lenghty duration.
* Glaives of Wisdom will reduce temporarily Necrophos intelligence on each hit dealing hindering his ability to spam Death Pulse, also reducing his attack damage and mana pool; dealing increasing amounts of phisical and pure damage each time. Silencer will permanently steal Necrophos intelligence if killed by him or dies nears him.
* Global Silence turns Necrophos almost useless for a long time, allowing your team to easily dispatch him, since he heavily relies on his spells to survive.

* Zeus can deal a huge amount of damage, but he lacks defensive abilities, such as good mobility or resistance. Due to that, he doesn't like to be touched by any means. Heroes with higher damage output and good mobility will often get easily near Zeus and trade damage (eventually causing Zeus's downfall). Such Heroes include: Lycan, Slark, Storm Spirit, Spectre and others.

* Silencer's Global Silence will render Zeus useless for 6 seconds in a team fight.
* Arcane Curse will punish Zeus for casting spells, which can cause continuous damage to him should he continue to cast spells.
* Last Word can silence Zeus and prevent him from spamming his spells.
* Silencer often builds Orchid Malevolence (or Bloodthorn) which can be used on spell casters like Zeus, forcing him to invest in a Linken's Sphere.
Additional:
* Zeus' main source of damage is his low cooldown, high damage spells - meaning Last Word and Global Silence will pretty much take him out of the game for the duration.
* Zeus likes to spam his abilities, which makes him vulnerable to Arcane Curse.
* If Zeus dies near Silencer, he will lose intelligence, reducing his mana pool, mana regen and attack damage. Furthermore, if the game is long and Zeus dies often, the intelligence losses will also reduce his spell damage.

* Pounce also stops Nature's Prophet's Teleportation.

* Heroes that can jump on her: Slark, Queen of Pain, Anti-Mage

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Generally strong against every spellcaster, Puck fully relies on their skill set and is barely a threat when silenced.
* Arcane Curse disables Blink Dagger for quite some time, and is also effective against Puck as he tend to use his spells a lot.
* Glaives of Wisdom can do a lot of damage against Puck due to Puck's low agility gain and armor.
* Last Word can prevent Puck from getting his full combo off, limiting his effectiveness in team fights or ganks.
* Global Silence can take Puck out of fights entirely.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* In general, heroes such as Lion, Silencer, Skywrath Mage, Sven, Ogre Magi and others with reliable disables are crucial to killing Techies before they can suicide.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Heroes with invisibility and high mobility can jump on and focus down Earthshaker before he has a chance to initiate: Clinkz, Slark, Storm Spirit

* Silencer's Global Silence and Doom's Doom makes Earthshaker temporarily useless.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Arcane Curse deals repeated stacks of damage to Timbersaw because he relies on constantly using his abilities.
* Glaives of Wisdom deals pure damage and when cast manually, nearby creeps will not attack silencer, making it an effective harassment tool.
* Although Last Word takes a while to trigger, it will break Timbersaw's ability combo and can be used to silence him.
* Global Silence will silence Timberaw no matter where he is on the map. This can be used to help allies get a kill on him, or prevent Timbersaw from killing someone.
Additional:
* Timbersaw is heavily reliant on his abilities for damage and escape, allowing Silencer to effectively disable him and make him useless in both team fights and 1v1 scenarios.

* Silences and other types of lockdown that prevent Weaver from using his spells: Silencer, Riki, Lion, Legion Commander, Shadow Shaman, Bane.

* Windranger heavily relies on her abilities for any form of tactical advantage and damage. A well timed silence will make her useless: Puck,Silencer, Death Prophet, Skywrath Mage, Drow Ranger, Earth Spirit, Grimstroke.

Additional:
* Silencer's abilities hamper Windranger's effectiveness in battle, preventing her from comboing abilities and escaping using Windrun.

* Slark with Dark Pact
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Heroes with silence such as Riki, Silencer, or Night Stalker prevents Skywrath Mage from using his spells.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Both Arcane Curse and Last Word punishes casters with spammable spells such as Sand King.
* As a strength caster, Intelligence Steal reduces Sand King's mana pool even more.
* Global Silence silences Sand King, effectively reducing Sand King's initiation and counter-initiation potential. It can also interrupt channeling of Epicenter.

* Heroes with strong dispels can remove Primal Roar's stun: Abaddon, Slark, Oracle.

* Heroes with escaping and disjointing abilities can be good against Juggernaut: Riki, Queen of Pain, Puck, Storm Spirit, Ember Spirit, Slark etc.

* Heroes with good escapes can usually outmaneuver and escape from Spectre: Slark, Clinkz, Weaver

Additional:
* Essence Shift deals 20 extra damage by draining one strength per hit, which cannot be reduced or spread by Dispersion.
* Pounce prevents Spectre from escaping from or chasing with Spectral Dagger.
* Haunt illusions usually don't deal a lot of damage to Slark as he tends to buy a Shadow Blade, preventing Desolate's and Diffusal Blade's damage and activating Shadow Dance's regeneration to make up for any damage caused by Radiance.

* Heroes who have a high mobility (Queen of Pain, Storm Spirit, Slark, etc.).

* A well-timed Global Silence prevents Dazzle from saving allies with Shallow Grave or Shadow Wave. Items that could dispel the silence are expensive, and difficult for Dazzle to farm from a support role.
* Arcane Curse and Last Word cause long damage over time, which may outlast Shallow Grave.

* Silencer's Last Word and Global Silence prevents Jakiro from casting any spell.
* A carry Silencer can easily take down a support Jakiro with his Glaives of Wisdom.

* Shadow Dance prevents Luna from damaging Slark, and together with Shadow Blade he can kite her or escape.
* Luna has no way to escape from Pounce's leash.
Additional:
* Luna's lack of mobility and escape abilities makes her easily gankable by Slark.
* Shadow Dance will avoid all the damage from Eclipse.
* For the same reasons, Slark is a good ally for Luna when they are in the same team.

* Dark Pact, if timed correctly, can dispel Wraithfire Blast's stun and slow.
* Since Wraith King has a lot of health and multiple lives, Slark can keep gaining Essence Shift stacks, increasing armor, damage, and attack speed and can beat down Wraith King twice.
* Slark sometimes carries Diffusal Blade to burn mana as an attempt to shut down Reincarnation.
* Because Wraith King has no AoE abilities, Shadow Dance is particularly useful against Wraith King.

* Flux is dispelled by Dark Pact.
* Pounce allows Slark to avoid Spark Wraiths.
* Tempest Double allows Slark to build up Essence Shift stacks, especially when it is being used for split pushing.

* A well-timed Dark Pact can dispel Frost Arrows and Gust, letting Slark engage and escape freely.
* Shadow Dance lets Slark quickly close the gap and deal heavy damage without giving Drow Ranger a chance to retaliate.
* Pounce counteracts Frost Arrows' slow, letting Slark easily pin Drow Ranger down or flee.
Additional:
* Pounce and items like Shadow Blade makes it very difficult for Drow Ranger to keep her distance from Slark, thereby losing her Marksmanship bonus.
* Gust is rarely enough to keep Slark at bay, as Drow Ranger has no movement abilities and will simply be chased down afterwards.
* Drow Ranger's heavy dependence on agility also makes her significantly weaker after being drained by Essence Shift.

* Basically, Heroes that heavily rely on abilities for damage or escape, such as Queen of Pain and Storm Spirit.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Heroes with dispels: Legion Commander, Oracle, Slark

* Slark is a natural Shadow Blade carrier, and with Pounce Sniper has no opportunity to escape or react.
* With Essence Shift and Shadow Dance, Slark will easily win a fight against Sniper.
Additional:
* Sniper is one of the most gankable heroes in the game, and has no defenses when Pounced on by Slark.

* Silencer's intelligence steal will heavily reduce Outworld Devourer's damage output, if Outworld Devourer dies a lot near/to Silencer.
* Global Silence and Last Words will render Outworld Devourer helpless unless he has dispelling item/ally.
Additional:
* Silencer's Intelligence Steal will heavily reduce Outworld Devourer's damage output, particularly from Sanity's Eclipse.
* Last Word and Global Silence will take Outworld Devourer out of the fight unless he has built Black King Bar.

* Slark can detect early Roshan attempts due to Shadow Dance if he frequently checks the Pit.
* Enrage cannot restore attributes stolen by Essence Shift and will reduce his physical damage output.
* Even if Ursa initiates with Earthshock, Slark can Pounce away or use Dark Pact after Ursa's initiation to avoid Fury Swipes' damage until Earthshock's slow is gone.

* Slark's Pounce allows him to close the gap on Phantom Assassin and prevent her from escaping with Phantom Strike.
* As a hero who always goes for the Silver Edge and Abyssal Blade Slark can use it to disable Phantom Assassin and her Blur and Coup de Grace, drastically reducing her damage output and ability to evade attacks, and also preventing her from acting.
* Phantom Assassin's Coup de Grace requires Random Number Generation in order to proc, which gives Slark more than enough time to escape and recover himself.

* Heroes that have long silences, such as Night Stalker and Silencer, will prevent Abaddon from saving his allies effectively and disable the active component of Borrowed Time.

* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

Additional:
* Dark Pact rips through Refraction charges and still steals attributes during Refraction.
* Pounce and Dark Pact will still hit Templar Assassin while she is Melded. Since she cannot move, both abilities will be easy for Slark to land.

* Global Silence takes Omniknight out of the fight completely.
* Glaives of Wisdom are a great harass vs Omniknight during the laning stages of the game, since it doesn't aggro creeps & ignores his high base armor. It deals pure damage, which means it can also go through Guardian Angel.
* Silencer's intelligence steal can also cause Omniknight to falter in the early phases as it reduces his ability to use his spells.

* Heroes with pure damage can kill Huskar when he inevitably gets low on health: Outworld Devourer, Silencer.

* Oracle's reliance on spamming his spells can be easily hindered by Silencer's Arcane Curse.
* Last Word and Global Silence negates Oracle's attempt to save his allies with his spells.
* Fate's Edict is useless against Glaives of Wisdom's pure damage.

* Crystal Maiden is squishy, is heavily spell reliant, has low base Intelligence, and is naturally slow, making her an ideal target for Silencer
* Crystal Maiden's Freezing Field has a similar cooldown to Global Silence, therefore, Freezing Field can almost always be canceled to ruin aggressive Crystal Maiden initiations.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Dark Seer relies on Surge for most of his mobility, so he's not very vulnerable to slows, but much more to root effects and walls or pseudo-walls such as Disruptor's Kinetic Field or Slark's Pounce.