* Nature's Prophet can literally do nothing against Spectre, because she can chase him from anywhere with Haunt.
* Spectre, just like Naga Siren, loves buying Radiance, which can kill Nature's Prophet's treants, and grant her farm simultaneously.
Additional:
* Spectre can get to him anywhere on the map with Haunt.
* Spectre can pass through his trees with Spectral Dagger.
* Desolate's damage will melt him quickly, as he's alone most of the time.

* Doom can eats Nature's Prophet's treants with Devour and gains lots of gold.
* Doom usually buys Radiance or using his Scorched Earth deals a lot of damage to Nature's Prophet if they stand close to his Treants, as well as killing all of his Treants and getting lots of gold.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Nature's Prophet:
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer, Satyr Tormenter and etc. are good examples.
* Doom and a ministun from Infernal Blade's prevents Nature's Prophet from escaping with Sprout and Teleportation.

* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Axe more than most normal attacks, negating some of his durability.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Axe.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom's naturally low attack speed makes Counter Helix less likely to proc, and his high base health allows him to take a few Helixes with no danger.
* Doom makes Axe less disruptive, preventing him from using his skills or items. With Aghanim's Scepter, Counter Helix is also disabled, making him effectively useless for a lengthy duration.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Axe.
* Doom has low attack speed because of his high Base-Attack-Time, poor agility gain and limited attack-speed granting items which are commonly built. This means Doom will trigger Counter Helix less often and thus is an unideal target for initiation.
* Doom has naturally high HP so it takes longer for Doom to be brought down to the killing threshold of Culling Blade.
* Axe is highly reliant on his abilities and items to be effective during a fight. Without the usage of Berserker's Call and Blink Dagger due to Doom, Axe offers very little in the way of damage, effectively removing him from a fight.

* Dispersion makes Spectre very durable, making it much less likely for Axe to bring her low enough for Culling Blade.
* Spectre can simply use Spectral Dagger to escape against an Axe gank.

* Haunt can ruin Enigma's initiation with Blink Dagger, no matter where he is on the map.
* Dispersion reflects the damage of Midnight Pulse and Black Hole inflicted back to Enigma.

* Doom pierces spell immunity and can prevent Enigma from casting any spells or using items until the duration of the spell depletes, as well as damaging him over time. This can however, be blocked by a Linken's Sphere.
* An Enigma with a Helm of the Dominator can potentially feed his dominated creeps to Doom's Devour, giving Doom the abilities and benefits instead.

* His global teleportation with Boots of Travel and Rearm is easily countered with Haunt, and Spectre can reach him anywhere on the map.
* He is squishy, and if alone Desolate will kill him very fast.
* Laser's blind isn't reliable, since Desolate cannot miss. Even worse, Dispersion can reflect and reduce his burst damage.

* Tinker is heavily reliant on casting his spells and Doom can disable all of his abilities and items. An Aghanim's Scepter only makes it harder for Tinker to survive.
Additional:
* Tinker is heavily dependent on active abilities and Doom prevents him from using any of them.

* Doom, Disruptor with Aghanim's Scepter, and hex abilities all prevent item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility.

* Black King Bar is useless for Phantom Assassin against Spectre, since all of the Spectre's abilities go through spell immunity,
* Blur cannot evade Desolate because its damage is a separate damage instance and is applied before the attack hits.
* Spectre's high durability provided by Dispersion and damage block items makes her one of the hardest carries to take down.
Additional:
* Dispersion makes it hard for Phantom Assassin to burst down Spectre while also reflecting back Phantom Assassin's high burst damage against herself.
* Desolate ignores the evasion from Blur.
* Black King Bar is useless against Spectre as all of her skills pierce spell immunity.

* Spectral Dagger can be used to traverse past Fissure.
* Haunt will usually disable Earthshaker's Blink Dagger prior to a teamfight, preventing him from initiating.
* On the other hand, Haunt will amplify damage done from Echo Slam. Use this to your advantage.
Additional:
* Spectre can use Haunt to intercept and disrupt Earthshaker's initiation attempts.
* Spectral Dagger can be used to traverse past Fissure.
* Earthshaker often travels alone when he is trying to initiate, so Desolate can be very effective against him.
* Beware that the Haunt illusions amplify the damage done from Echo Slam, which can prove fatal for Spectre's own team.

* Silencer's Global Silence and Doom's Doom makes Earthshaker temporarily useless.

* Doom alone can easily pick off Crystal Maiden since she is fairly fragile, even with using only basic attacks, Infernal Blade, and Scorched Earth.
* Doom prevents her from using any abilities in a fight, making her impact negligible.
* Devour allows Doom to acquire a stun, allowing him to cancel Freezing Field without having to use Doom.

* As Crystal Maiden is squishy with very bad movement speed, Spectre can easily stay on Crystal Maiden with Haunt and Spectral Dagger.
* Late game, with enough farm, Spectre can withstand an entire Freezing Field, possibly even causing Crystal Maiden to kill herself from Dispersion.

* Spectre can instantly escape Burning Army or hunt Clinkz with Haunt.
* Spectre can catch up to him with Spectral Dagger, even if he uses Skeleton Walk.
* Desolate allows Spectre to hit Clinkz through Skeleton Walk.
* Dispersion makes Spectre tanky and also reflects some damage back to Clinkz.
Additional:
* Spectre can catch Clinkz with Spectral Dagger, even if he uses Skeleton Walk.
* Spectre can instantly reach a ratting Clinkz with Haunt.
* Desolate's damage will melt him quickly, as he's alone most of the time.

* Scorched Earth deals damage to Clinkz during Skeleton Walk.
* Doom shuts down Clinkz entirely, as it prevents him from casting any of his spells and contributing a large amount of damage in teamfights.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Timbersaw.
* Timbersaw is extremely reliant on his abilities to be effective during a team fight - both for mobility, damage and crowd control. Timbersaw offers very little impactful right-click damage, and thus Doom is particularly crippling against this hero.
* Additionally, when upgraded with Aghanim's Scepter, Doom breaks Reactive Armor, which effectively removes the durability which Timbersaw is commonly known for.
Additional:
* Doom shuts down Timbersaw completely, negating his mobility and preventing him from doing any damage. It also breaks Reactive Armor's passive bonuses from Aghanim's Scepter.
* Infernal Blade can stun Timbersaw several times in a fight, potentially interrupting Timber Chain. Also it's useful since Timbersaw has high HP due to the damage scales based on max HP.

* None of Spectre's spells are very good for Rubick to Spell Steal.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Tidehunter.
* Doom prevents Tidehunter from casting his Gush, Anchor Smash and Ravage, making him useless in team fights.
* If Doom gets an Aghanim's Scepter, he can also disable Kraken Shell, reducing his survivability.

* Spectral Dagger and Haunt allow Spectre to get close to Lina.
* Desolate is very strong against Lina, who's usually a bit isolated in fights because of her high attack and cast range.
* Dispersion can mitigate a good portion of Lina's burst damage, allowing Spectre to turn on her afterwards.
Additional:
* Spectre can very easily close the distance on Lina with Haunt and Spectral Dagger, and due to Lina's abysmal mobility without a Blink Dagger and terrible health pool and armor, Lina easily gets slaughtered due Desolate.
* Dispersion can mitigate a good portion of Lina's burst damage, allowing Spectre to turn against her afterwards.

* Ember Spirit cannot use his Activate Fire Remnant to escape while under effect from Doom.

* Spectre can use Haunt to intercept and disrupt Magnus's initiation attempts.
* Spectral Dagger can severely slow down Magnus after he uses Skewer.
* Magnus often travels alone when he is trying to initiate, so Desolate can be very effective against him.
* In late game, Spectre can survive Reverse Polarity initiation thanks to Dispersion.
Additional:
* Spectre disables Magnus' Blink Dagger using her ultimate, and later into the game can usually outlive Reverse Polarity's duration.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Bristleback.
* Doom prevents Bristleback from casting his two low cooldown abilities, which then prevents him from utilizing Warpath.
* If Doom gets an Aghanim's Scepter, he can disable Bristleback and Warpath, taking away much of his durability and damage potential in team fights.
Additional:
* Infernal Blade deals scaling damage and is useful against high health targets such as Bristleback.
* Doom disables Bristleback's low cooldown abilities, preventing him from triggering Warpath. With Aghanim's Scepter, it also breaks Bristleback's passive, rendering him more vulnerable.

* Doom completely takes Invoker out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Additional:
* Doom is a good way to shut down Invoker, preventing from casting spells and using items for a lengthy time, thus forcing him to invest on Linken's Sphere.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Elder Titan. It also can interupt Echo Stomp if quick enough.
* Doom has very low base armor and naturally high HP, so he isn't significantly affected by Natural Order.

* Spectre can instantly escape Focus Fire or hunt a Windranger with Haunt.
* Spectre can catch up to her with Spectral Dagger, even if she uses Windrun.
* Desolate allows Spectre to hit Windranger through Windrun.
* Dispersion makes Spectre tanky and also reflects some damage back to Windranger.
Additional:
* Spectre can catch up to her with Spectral Dagger, even if she uses Windrun.
* Spectre can instantly reach a ratting Windranger with Haunt.
* Windrun's miss chance is countered by Desolate.
* Dispersion can reflect some of her damage, especially from her Focus Fire.

* Doom has several disable abilities to choose from jungle creeps (e.g. War Stomp, Ensnare) to deal with Shadow Fiend who lacks escape abilities.
* When Doom combines creep abilities with Scorched Earth, Infernal Blade, and Doom, Shadow Fiend most likely will die as he cannot use Shadowraze and Requiem of Souls to protect himself, and also cannot even flee by using Shadow Blade or Blink Dagger.
* Although Shadow Fiend has a high physical damage output, Doom has a large health pool to survive it, meaning Doom's combo with high magical damage output will shutdown Shadow Fiend first.
* Doom usually buys Radiance to improve his damage, making his nuke combo more deadly to Shadow Fiend. The blind also prevents Shadow Fiend from landing his attacks often.

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

* Oracle's burst damage is not enough to take down Spectre due to Dispersion.
* Disarm from Fate's Edict does not hinder Spectre that much, since she can deal damage even without landing a single attack.
Additional:
* Oracle's burst damage is ineffective against Dispersion.
* Disarm provided by Fate's Edict is not as significant debilitation for Spectre as it might be for other carries since She can do damage even without landing attacks.

* Faceless Void relies on Time Walk for mobility and survivability but he can be prevented from utilizing it through Doom.
* Doom has a high cooldown duration for every ability except Infernal Blade, so he is not significantly affected by Time Dilation.

* As Ancient Apparition likes to stay far away from the fight to get full effectiveness from Ice Blast, he is a very good target for a Haunt gank.
* Ancient Apparition also has no hard disables and escape spells, making him an easy kill for Spectre.

* Doom can stop Death Prophet from casting spells, which makes her useless during team fights if she didn't cast Exorcism before the fight. Furthermore, Doom can use Scorched Earth to chase after her.

* Spectre can instantly reveal Bounty Hunter's position on the activation of her ultimate Haunt. She can also semi-reveal( visible but not target-able) Bounty Hunter by hitting him with Spectral Dagger.

* Arc Warden relies on items and abilities, as well as his Tempest Double, to deal damage to enemies. Doom effectively denies that and makes Arc Warden useless in fights.

* Doom can completely shut down Dazzle through Doom, as it prevents him from casting his abilities and, by extension, gaining Bad Juju stacks.

* Spectre's entire ability set is designed to get to and destroy heroes that stay in the backlines, both carries (like the aforementioned Drow Ranger and Sniper) and supports (like Dazzle and Shadow Shaman).

* Doom makes Ursa less disruptive, and it cannot be dispelled with Enrage upgraded with Aghanim's Scepter.
* Aghanim's Scepter upgraded Infernal Blade can break Fury Swipes, negating much of his damage output.

* Doom makes Ogre Magi less disruptive.
* Infernal Blade effectively negates Ogre Magi's durability.
* With Aghanim's Scepter, he can disable Multicast.

* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: Lifestealer, Doom, Mirana, Clinkz.

* Squishy heroes without good escape mechanism: Crystal Maiden, Chen.

* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper

* Supports with useful teamfight or contribution spells will be helpless against Doom: Dazzle, Oracle, Warlock.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Heroes with abilities that break Berserker's Blood, lowering Huskar's attack speed and health regeneration: Doom, Shadow Demon, Viper.

* Doom is effective against every hero, and Void Spirit is no exception. Being unable to cast spells or items during fights for 16 seconds nullifies his impact entirely.
* Doom has a very versatile build and can consume creeps which has abilities that can stun or provide additional magic resistance.
* Doom's high strength gain and versatility in items can be effective against Void Spirit's magical damage.

* Haunt instantly allows her to get up and close with Sniper, and Spectral Dagger makes it difficult to escape from her.
* Spectre outcarries Sniper in the late game, so Sniper must try to end the game early before Spectre comes online.
Additional:
* Spectre can reach him easily in the backlines with Spectral Dagger or teleport to him with Haunt.
* He is usually a fair distance away from his allies, so Desolate will quickly tear Sniper down.
* Dispersion reflect or reduce his damage, making her hard to take down even at late game.

* Doom will make Abaddon unable to use Mist Coil, Aphotic Shield, and the active component of Borrowed Time, also upgraded with Aghanim's Scepter can break Curse of Avernus and the passive component of Borrowed Time ,which means his allies could be easily disabled or killed.

* A well-timed Doom prevents Nyx Assassin escaping with Vendetta and does not allow him to disengage with Spiked Carapace.
* Doom's high HP easily shrug off Nyx Assassin's burst damage and fend him off.

* Spectral Dagger hinders Sven's low movement speed, and can be an easy tool to escape against his high damage.
* Dispersion makes it harder for Sven to burst down Spectre in one on one fights, and can reflect Sven's high damage back to him or his nearby teammates.
* Haunt and Radiance disables Sven's Blink Dagger.
* Desolate's pure damage ignores Sven's high armor.
* Spectre should not attempt to stand up to a full slotted Sven, since she will get shredded.

* Doom prevents Storm Spirit from using all of his abilities and items, rendering Storm Spirit useless in a fight.

* Heroes with silencing abilities can be particularly deadly when Slark is trying to escape: Silencer, Death Prophet, Puck, Doom

* An Aghanim's Scepter upgraded Doom can be useful against heroes with troublesome passive skills while also disabling them for a long time: Phantom Assassin, Enchantress, Huskar, Underlord.

Additional:
* Infernal Blade does damage based on percentage health, and is useful against high health pool hero like Underlord
* Doom can prevent Underlord from spamming his abilities and most important is prevent him from using Dark Rift to escape

* Doom disables the toggling of Rot and, if cast at the right time, may leave Pudge with a potentially lethal health drain.
* Doom's naturally high health, strength gain and damage output makes him a poor target for Pudge.
* The damage of Doom's Infernal Blade scales with the target's maximum health, which is particularly effective against Pudge due to his naturally high health and further health granted by stacks of Flesh Heap.
Additional:
* Infernal Blade deals high damage to Pudge due to his high strength grow with Flesh Heap.
* Using Doom with timing against Pudge who had just activated Rot would usually kill him.

* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.

* Doom shuts down Anti-Mage's escape capabilities with Blink. The ability also deals pure damage, which ignores the protection from Counterspell.
* However, a well-timed Counterspell can reflect it back.
* If Doom has Aghanim's Scepter, Doom can break Mana Break and Counterspell, weakening both his offense and defense.
* Doom's low mana pool causes him to take little damage from Mana Void.
Additional:
* Doom prevents Anti-Mage from maneuvering around a fight or escaping from an initiation using Blink. Additionally, Doom deals pure damage, which is not affected by Counterspell. This can quickly whittle away Anti-Mage's naturally poor health pool.
* Be careful when using Doom as a well-timed Counterspell can block and reflect it back against Doom himself.
* An Aghanim's Scepter upgraded Doom will also disable Mana Break and Counterspell, which makes Anti-Mage significantly less effective in fights and more susceptible to the high magical damage of Doom's abilities and his allies.

* Spectral Dagger follows Riki even after he goes invisible and stays on him through Tricks of the Trade, revealing his location.
* Desolate grants Spectre the ability to damage Riki with right clicks regardless of Smoke Screen's blind.
* Riki relies on his high damage to kill is opponents, which is countered by Dispersion.
* Haunt can find Riki globally at any time, negating much of his ganking potential.

* Spectre can easily close the distance on Drow Ranger with Haunt and stick on her with Spectral Dagger, effectively disables her Marksmanship.
* Spectre does not care if silenced by Gust, since Spectre will catch her up regardless.
* Dispersion can reflect some damage back to Drow Ranger should she chooses to attack.
* Be careful once she got her Silver Edge as an attempt to shut you down.

* Scorched Earth can be used to engage Visage while removing Gravekeeper's Cloak charges.
* Infernal Blade will deal tremendous amounts of damage over time due to Visage's high health pool.
* Doom completely nullifies Gravekeeper's Cloak and prevents Visage from casting spells.

* Zeus can deal a huge amount of damage, but he lacks defensive abilities, such as good mobility or resistance. Due to that, he doesn't like to be touched by any means. Heroes with higher damage output and good mobility will often get easily near Zeus and trade damage (eventually causing Zeus's downfall). Such Heroes include: Lycan, Slark, Storm Spirit, Spectre and others.

Additional:
* Zeus burst damage can be reduced by Dispersion and reflect some of the damage back to Zeus himself.
* Zeus has low mobility and stays in backlines, Spectral Dagger or Haunt can easily catch him as he has no escape mechanism.
* Since Zeus has low HP, Spectral Dagger and Desolate will quickly tear Zeus down when he's alone.

* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .