* Anti-Mage usually relies on Blink to escape, but with vision from Charge of Darkness it is easier to catch him.
* Spirit Breaker could single-handedly lock Anti-Mage down for 4 seconds (or even more with lucky bashes), allowing his teammates to follow up.
* As Anti-Mage is an elusive hero who likes to farm alone, Spirit Breaker could choose to charge whenever Anti-Mage is in sight.

* Arcane Orb's pure damage goes through Counterspell, and deals splash damage to illusions spawned from Manta Style.
* Sanity's Eclipse hits Anti-Mage while he is disabled with Astral Imprisonment, and forces him to take heavy damage due to his low intelligence.
* Essence Flux keeps Outworld Destroyer at high mana, thus greatly reducing the damage from Mana Void.
Additional:
* Counterspell doesn't work versus Arcane Orb because it does pure damage.
* Anti-Mage cannot burn all of Outworld Devourer's mana without disables due to Essence Flux.
* Anti-Mage's Manta Style illusions are quickly destroyed by Arcane Orb.
* However, if the enemy has multiple means of removing mana, Mana Void becomes a threat to Outworld Devourer, Anti-Mage has better mobility than Outworld Devourer with Blink, and Counterspell blocks a large portion of the damage from Sanity's Eclipse.

* Charge of Darkness can be used to chase down Pangolier if he escapes with Swashbuckle or Rolling Thunder.
* Nether Strike ignores Rolling Thunder's spell immunity, and will still hit Pangolier if he rolls or dashes away.

* Astral Imprisonment protects an ally for much of Rolling Thunder's duration, especially at the lower levels. As Rolling Thunder has a considerable cast animation, an Outworld Destroyer with Blink Dagger can initiate on him and destroy his timing.

* Heroes with long-lasting, undispellable debuffs will pinpoint the true Naga Siren: Spirit Breaker, Bloodseeker.

* Sanity's Eclipse will likely instantly kill all illusions.

* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.

* Heroes that rely on escapes to stay alive can be caught and locked down for a long time: Queen of Pain, Phantom Assassin

* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Heroes with pure damage can kill Huskar when he inevitably gets low on health: Outworld Destroyer, Silencer.

Additional:
* Outworld Devourer can dodge Life Break with Astral Imprisonment, leaving him unharmed while Huskar loses HP.
* Sanity's Eclipse can deal massive damage to Huskar before he builds up his Berserker's Blood stacks due to Huskar's low mana pool.

* Spirit Breaker's stuns pierce spell immunity, making him a good choice against heroes that heavily rely on Black King Bar; Huskar

* Astral Imprisonment can allow Outworld Destroyer to save himself or allies from Kunkka's full kit.
* Sanity's Eclipse deal a large amount of damage, as Kunkka's mana pool is much smaller than Outworld Destroyer's.
* Arcane Orb deals pure damage, shredding through Kunkka and his team even with Ghostship's buff.

* Spirit Breaker can chase Nature's Prophet from anywhere on the map with Charge of Darkness, making it hard for Nature's Prophet to split-push.
* Charge of Darkness and Nether Strike gives vision of Nature's Prophet when he tries to Sprout himself and teleport away.
Additional:
* Charge of Darkness allows Spirit Breaker to catch Nature's Prophet out when he tries to split push.
* Nature's Prophet can't hide in his Sprout against Spirit Breaker, as his Charge of Darkness provides vision on its target.
* Spirit Breaker can easily cancel Nature's Prophet's Teleportation.

* Magic Missile has a considerably long cast time, making it difficult to stop Charge of Darkness with it.
* Other than Magic Missile, Vengeful Spirit has no way of canceling Nether Strike.

* Sanity's Eclipse only triggers Bristleback's passive once, and deals high damage against Bristleback's low intelligence.

* Spirit Breaker's Nether Strike with Aghanim's Shard disables Bristleback's passives.

* Arcane Orb deals heavy damage to both Lone Druid and the Spirit Bear.
* Astral Imprisonment can prevent the Spirit Bear from attacking, which is Lone Druid's main damage output.
* Sanity's Eclipse deals heavy damage to Lone Druid.

* Charge of Darkness allows Spirit Breaker to gank Shadow Fiend in the early game, preventing him from getting Necromastery stacks.
* Nether Strike and Charge of Darkness can be used to prevent Shadow Fiend from casting Requiem of Souls.

* Arcane Orb deals pure damage against the real Terrorblade, bypassing his high base armor.
* Arcane Orb and Sanity's Eclipse will make very short work of Terrorblade and his illusions.

* Arcane Orb and Sanity's Eclipse quickly drains Pudge's limited mana pool, making him unable to use Meat Hook or Dismember and also bypasses Flesh Heap.
* Outworld Destroyer can save allies or himself caught by Dismember or Meat Hook with Astral Imprisonment.

* Arcane Orb's pure damage ignores Mars' Bulwark.
* Astral Imprisonment can be used to stop Mars from being disruptive or save allies from his abilities.
* Sanity's Eclipse deals high damage to Mars, due to his low intelligence.

* Arcane Orb deals constant pure damage, which bypasses Timbersaw's Reactive Armor.
* Sanity's Eclipse can hit targets inside Astral Imprisonment, which helps Outworld Destroyer finish off Timbersaw before he escapes with Timber Chain. It can also drain his mana, limiting his ability to escape should he survive.
Additional:
* Arcane Orb's pure damage ignores Timbersaw's Reactive Armor.
* Astral Imprisonment, if timed correctly, can interrupt Timber Chain, preventing him from escaping.

* Outworld Devourer's pure damage from Arcane Orb can go through Cold Embrace.
* Outworld Devourer can negate the healing from Cold Embrace using Astral Imprisonment, and steal mana while doing so.
* Outworld Devourer's damage during Winter's Curse is reduced due to Arcane Orb being unable to target allies.
Additional:
* Winter Wyvern must never put her allies in Cold Embrace against Outworld Destroyer as Arcane Orb will continue to steal Intelligence and deal damage to the defenseless hero.
* Arcane Orb does not hit his allies when he is taunted by Winter's Curse, making it weak against allies, but strong versus enemies.
* Astral Imprisonment can protect a target inflicted with Winter's Curse.

* Outworld Destroyer's pure damage will mop up Primal Split's units very quickly.

* Charge of Darkness keeps vision of Monkey King, even when he is in the trees.
* Nether Strike locks onto Monkey King and focuses damage on him during Wukong's Command.

* Charge of Darkness can be used to escape or counter-initiate against a Relocate gank.
* Greater Bash and Nether Strike is devastating due to Io's low armor, and can even knock it away from tethered target.

* Astral Imprisonment wastes Borrowed Time's duration.
* Outworld Destroyer's Sanity's Eclipse can kill Abaddon before Borrowed Time triggers.

* Outworld Destroyer's pure damage from Arcane Orb is very effective at killing Troll Warlord quickly.
* Astral Imprisonment removes Troll Warlord from a fight for four seconds, minimizing his contribution to a teamfight, and potentially wasting over half of Battle Trance's duration.
* Troll Warlord gains a measly 1 intelligence point per level, meaning Sanity's Eclipse is especially effective, often instantly killing him.

* Possibly Clinkz's worst enemy. He has many tools to utterly destroy Clinkz.
* Charge of Darkness can be used on Clinkz if Spirit Breaker's team spots him anywhere. This charge will track his location through Skeleton Walk's invisibility and movement speed bonuses.
* When Spirit Breaker charges onto Clinkz, he can easily use Dust of Appearance to guarantee a reveal on him while stunned.
* All three of Spirit Breaker's spells help him and his team quickly close the gap to Clinkz even at the edge of his attack range or when running away with Skeleton Walk.
* Spirit Breaker's high strength and above average armor makes him able to endure Clinkz's onslaught, meanwhile Clinkz will be heavily threatened if Spirit Breaker procs a Greater Bash.
Additional:
* Once caught with dust, Clinkz could be locked down for a long time by Spirit Breaker and has nowhere to escape.
* Charge of Darkness provides shared vision over its target, showing Clinkz even when he is in Skeleton Walk.

* Spirit Breaker's Charge of Darkness semi-reveals Bounty Hunter, taking away his element of surprise for the duration of the charge. Also, as Charge of Darkness shows Bounty Hunter's position, Spirit Breaker's allies can proceed to gank Bounty Hunter while he is roaming alone.

* Any hero that can nullify effects of Chronosphere: (Omniknight, Keeper of the Light with Aghanim's Scepter during daytime, Winter Wyvern), banishing him or Faceless Void (Outworld Destroyer, Shadow Demon, Earth Spirit with Aghanim's Scepter) or protecting him in other ways (Dazzle, Oracle, Abaddon) can greatly limit Chronosphere's potential.

* Tanky melee heroes that can easily be kited, which allows Outworld Devourer to deal heavy damage with Arcane Orb from a distance: Sven, Underlord, Bristleback.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Shadow Demon, Outworld Destroyer and Tusk can all save a Lasso'd teammate with their defensive spells.

* Heroes who can hide the Dueled target (Outworld Destroyer, Shadow Demon, Tusk, Phoenix with Aghanim's Scepter etc).

Additional:
* Outworld Devourer can save an ally hero caught by Duel with Astral Imprisonment, and he can inflict heavy damage on Legion Commander with Arcane Orb to aid his ally. However, if he gets caught, he is unlikely to survive the duel, due to his lack of durability.

* Charge of Darkness provides shared vision over its target, keeping track of heroes who rely on invisibility, mobility, or illusions: Riki, Broodmother, Phantom Lancer

* Heroes who possess abilities that can save targets from being killed by Reaper's Scythe: Abaddon, Bane, Outworld Destroyer, Shadow Demon, Omniknight, etc.

* Warlock is a very strong hero when positioned correctly, and his long cast range helps him with this. However, some Heroes might disrupt or sneakily pass through your allies and deal with you, preventing you from doing your job. Such heroes include Chaos Knight, Spirit Breaker, Riki, and some others.

* Charge of Darkness provides shared vision over its target, keeping track of heroes who rely on invisibility, mobility, or illusions: Riki, Broodmother, Phantom Lancer

* Ursa struggles against heroes with strong (and especially undispellable) disables (Disruptor, Puck, Shadow Demon, Outworld Destroyer and etc).

* Illusion based heroes (like Chaos Knight and Terrorblade) can't use their illusion beneficially against Sanity's Eclipse's high AoE burst damage.

* Bristleback, Centaur Warrunner, Spirit Breaker, Pudge, Huskar: These heroes are too tanky for Puck to burst down. Also, all of them have spells which can deal with and shut Puck down reliably.

* Heroes with mobility/escape mechanisms to dodge Ancient Apparition abilites, or to easily jump on him: Riki, Queen of Pain, Phantom Assassin, Windranger, Bounty Hunter, Spirit Breaker, Night Stalker, Storm Spirit, Juggernaut, etc.

* Charge of Darkness provides shared vision over its target, keeping track of heroes who rely on invisibility, mobility, or illusions: Riki, Broodmother, Phantom Lancer

* Arcane Orb deals pure damage, effectively bypassing Morphling's high armor from Attribute Shift (Agility Gain).
* Sanity's Eclipse is more effective against a low health and mana pool Morphling, enabling Outworld Destroyer to burst Morphling down before he can shift to Strength.
Additional:
* Arcane Orb deals high damage regardless of Morphling's high armor from Attribute Shift (Agility Gain).
* Because of Morphling's very low intelligence gain and base intelligence, Sanity's Eclipse will almost always be effective against Morphling.

* Outworld Destroyer's pure and magical damage is particularly effective against Axe.
* Astral Imprisonment is an excellent way to defend against an initiating Axe.
* Sanity's Eclipse deals high damage to Axe due to his low mana pool.
Additional:
* Berserker's Call bonus armor doesn't block Arcane Orb's pure damage.
* Astral Imprisonment can be used to prevent an ally or Outworld Devourer himself from an Axe initiation.
* Axe's low mana means he's susceptible to a powerful Sanity's Eclipse.

* Astral Imprisonment is a versatile nuisance:
* If it is cast on a low-enough-health unit at least 1 second into Shallow Grave's duration, the Shallow Grave will end during the imprisonment, and the target will take lethal damage when released.
* It can be used remove Dazzle from the fight at a time he could have saved someone.
* It lets himself or an ally dodge all of Poison Touch's effects, for long enough to recover their Blink Dagger.

* Arcane Orb deals pure damage, which ignores armor granted from permanent agility stacks.
* Astral Imprisonment can disrupt any Pounce attempt by banishing the leashed ally.
* Slark's low intelligence and therefore mana pool makes him more susceptible to Sanity's Eclipse.

* Sanity's Eclipse does massive damage to Wraith King who naturally has a low mana pool and typically doesn't build items to increase it.
* Wraithfire Blast's slow projectile speed makes it easy to avoid using Astral Imprisonment.

* Astral Imprisonment allows Outworld Destroyer to save himself or his teamates during Omnislash.
* Juggernaut's low mana from his low intelligence gain means that he'll take a lot of damage from Sanity's Eclipse.

* Tinker relies on his high mobility from Boots of Travel and Blink Dagger to survive. Those items don't help him if Spirit Breaker manages to cast Charge of Darkness on him.
* Spirit Breaker can easily cancel Rearm and Boots of Travel.

* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.

* The pure damage provided by Arcane Orb is a great addition for killing Ember Spirit.
* Astral Imprisonment fully negates all magic damage of Flame Guard and Searing Chains and will temporarily save himself from Sleight of Fist's physical damage, and Ember Spirit is not a hero that can counter these skills.

* Heroes that rely on escapes to stay alive can be caught and locked down for a long time: Queen of Pain, Phantom Assassin

* Generally, heroes that can close the gap on Drow Ranger to cancel her Marksmanship such as Phantom Assassin, Spirit Breaker, and Tusk are effective at limiting her power and bursting her down.

* Arcane Orb's pure damage penetrates Guardian Angel's defense.
* Outworld Destroyer's intelligence steal is also devastating to Omniknight's already low mana pool.

* Arcane Orb's constant pure damage output is devastating to Dragon Knight.
* Dragon Knight's relatively low mana pool leads to heavy damage from Sanity's Eclipse, which also bypasses his armor.

* Outworld Destroyer's pure and magical damage is particularly effective against Earthshaker.
* Astral Imprisonment catches Earthshaker while he blinks in, preventing him from executing his combo.
* Earthshaker has mana troubles, and Outworld Destroyer's abilities can press this by stealing intelligence comes from Arcane Orb, therefore depleting his mana pool and mana regeneration.
* Sanity's Eclipse deals high damage to Earthshaker, due to his low intelligence and mana pool.

* Heroes with mana burn: Nyx Assassin, Invoker, Outworld Destroyer, Pugna

* Spirit Breaker can charge towards Sniper from anywhere on the map with Charge of Darkness.
* Greater Bash deals magical damage, which can prove dangerous to Sniper and his low health.
* Both previous abilities combined with Nether Strike ensures that Spirit Breaker can easily solo kill Sniper.

* Because Templar Assassin does not have escape potential in lane, any support hero with roaming potential and a Dust of Appearance can be great at shutting her down early game: Earth Spirit, Spirit Breaker, Tusk, Bounty Hunter, Riki, Warlock.

* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.

* Arcane Orb 's pure damage can do great damage to Underlord.
* Sanity's Eclipse can tear down Underlord's health by a large amount, since his mana pool is very low compare to OD's high mana pool.

* Heroes with hiding abilities can protect disabled allies: Outworld Destroyer, Shadow Demon, Tusk, Phoenix with Aghanim's Scepter

* Outworld Destroyer doesn't care if Razor steals his damage because he does most of his damage through Arcane Orb.
* Astral Imprisonment can prevent Razor from using the stolen damage from Static Link or chasing with Eye of the Storm.
* Sanity's Eclipse will do a ton of damage to Razor due to his low mana pool.