* Razor's Eye of the Storm damage-over-time easily wear off Refraction charges, allowing Templar Assassin to be damaged.
* Static Link empties Templar Assassin's damage output even with the bonus from Refraction, and will keep doing that even if the Razor cannot see her during Meld.
* Plasma Field and Storm Surge can easily strike her during Meld.

* Alchemist's reliance on fast attack speed to do single-target damage makes him vulnerable to Static Link. It also goes through Black King Bar, which is a standard item on Alchemist.
* Eye of the Storm is great against high health strength heroes as it reduces their survivability to physical damage.
* Razor has early lane push to counter Acid Spray.

* Heroes who can provide True Sight are always credible threats: Slardar, Bounty Hunter, especially Zeus since his Lightning Bolt provides True Sight without the need to detect her beforehand to apply the debuff. So even a late-coming Zeus can easily scout a large area to reveal her, and she cannot purge herself from his sight with the dispel talent.

* Corrosive Haze followed by Slithereen Crush takes advantage of Alchemist's main weakness, being physical damage before he has the change to improve his surviability with items.
* Bash of the Deep will deal lots of damage during the laning phase.
Additional:
* Alchemist has a low starting armor and a low agility growth, which translates to a low armor growth . And since it is very uncommon for Alchemist to get straight to Assault Cuirass, or Shiva's Guard, Corrosive Haze makes him too vulnerable to physical damage, even with the hp regeneration of Chemical Rage

* Pugna's Decrepify can render Templar Assassin's physical attacks useless.
* Pugna can also cast Life Drain on Templar Assassin, burning her Refraction instances.
* On the other hand, Pugna generally has low health and armor. Use this to your advantage.

* Pugna's Decrepify makes sure that either Alchemist is unable to hit anyone while also being slowed and susceptible to magical damage, or can protect an ally from physical attacks. Besides, Pugna can push early on, when Alchemist is not strong enough to repel it, so by the time Alchemist comes online, he might be forced to sit in base.

* Viper can bully Alchemist out of mid lane quite easily, forcing him to either retreat into jungle, or stay harassed in lane, and get very few last hits. Vipers break also completely disables Greevil's greed which prevents Alchemist to earn his amazing amounts of money.

* The damage over time from Viper's Poison Attack and Viper Strike rapidly wear down Refraction charges, allowing Templar Assassin to be damaged. Additionally, Corrosive Skin causes her attacks to apply damage over time on her as well.
* Nethertoxin is a big threat to Templar Assassin. Her initially low range making it very hard to deal against Nethertoxin in laning phase. At any stage of the game, a Nethertoxin can always force her to undo her Meld.
Additional:
* All of Viper's abilities quickly burn through Refraction charges.
* Templar Assassin's short range, aside from Psi Blades' spill damage, makes her vulnerable to Poison Attack harassment.
* Templar Assassin traditionally forgoes health and armor items for damage. Outside of Black King Bar, Viper will almost always be able to kill her when Refraction is down.

* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

Additional:
* Dark Pact rips through Refraction charges and still steals attributes during Refraction.
* Pounce and Dark Pact will still hit Templar Assassin while she is Melded. Since she cannot move, both abilities will be easy for Slark to land.

* Shadow Dance allows Slark to not be targeted by Unstable Concoction, making Alchemist stun himself and making himself vulnerable to the enemy.
* Dark Pact also allows him to just purge off the stun if timed correctly.
* Essence Shift will steal stats over long durations at a time should Alchemist lack the damage to kill Slark.

* In general, melee heroes without blink mechanisms or spell immunity will have a hard time positioning against Pit of Malice: Sven, Tiny, Wraith King, Dragon Knight, Meepo, Doom, Bounty Hunter, Dark Seer, Undying, Alchemist, Legion Commander.

* Firestorm will destroy Refraction charges very quickly.
* Firestorm will hit Templar Assassin while Melded.
* Templar Assassin has a hard time maneuvering around Pit of Malice.

* Ion Shell destroys Refraction's protection stacks in short time.
* Surge ignores the massive slow from Psionic Trap.

* Reaper's Scythe can kill Alchemist before Chemical Rage has the time to heal him.
* Ghost Shroud can prevent Alchemist from attacking Necrophos, as well as make him immune to Acid Spray and Unstable Concoction damage.
* Heartstopper Aura will do damage as long as Necrophos is alive based on health percentage, which is a problem for a strength hero such as Alchemist.

* Arc Warden's Flux tears through Refraction charges almost instantly. Should he have a Tempest Double and no creeps are around, a 75% slow means almost certain death.
* Meld is useless against Spark Wraith.
Additional:
* Flux wastes Templar Assassin's Refraction unless she has a Black King Bar or a Manta Style.
* Spark Wraith can be used to bully a Templar Assassin that used Meld.

* Windranger's Focus Fire tears apart Templar Assassin's refraction very quickly and easily bursts here down due to her low health pool against Windranger's immense attack speed
* Templar Assassin's "Psionic Trap" doesn't slow down Windranger due to her skill Windrun
* Templar Assassin's high damage can also be easily evaded thanks to Windrun's 100% evasion
Additional:
* Venomous Gale and Plague Wards allow to quickly melt through Refraction charges.
* Both Poison Nova and Venomous Gale hit invisible units, so Meld cannot be used defensively.

* Blade Fury's damage over time dispels Refraction almost instantly.
* Juggernaut's high armor allows him to survive for long enough to remove Refraction and threaten her with Omnislash as long as he or his team carries detection.
* Templar Assassin's short attack range makes it difficult for her to target a well-placed healing ward. She cannot splash onto it with Psi Blades.

* The damage block instances of Refraction can be burned down with Ignite.

* Attacks from Boars and Inner Beast will quickly wear down Refraction.
* True Sight provided by Level 3 Necronomicon can see Templar Assassin in Meld.

* Sand King can quickly remove her Refraction with his Sand Storm.
* Once Refraction is down, she is very vulnerable to Epicenter's high magic damage.

* Skywrath Mage can easily harass Alchemist in the laning phase with multiple Arcane Bolts. Additionally, if Alchemist is in the process of throwing an Unstable Concoction, and has no way to dispel Ancient Seal, the self stun becomes an easy set up for Mystic Flare.
* Caution, however, as a decently farmed Alchemist with {Item ID:Radiance} and {Item ID:Manta Style} can easily send illusions to harass and force Skywrath Mage out.

* Windranger's Focus Fire tears apart Templar Assassin's refraction very quickly and easily bursts here down due to her low health pool against Windranger's immense attack speed
* Templar Assassin's "Psionic Trap" doesn't slow down Windranger due to her skill Windrun
* Templar Assassin's high damage can also be easily evaded thanks to Windrun's 100% evasion

* Shackles and Mass Serpent Ward instantly destroy Refraction

* All of Jakiro's active skills can be targeted on an area, which is effective at forcing Templar Assassin to move should she Meld away.
* Many of Jakiro's spells utilize damage-over-time mechanics, which makes it easy to strip away layers of Refraction.

* The three Primal Split brewlings all attacking Templar Assassin at once will remove her Refraction quickly, especially with Fire's Permanent Immolation.
* Templar Assassin has no way to stop Brewmaster from using Primal Split by herself, and may get unlucky and miss her Meld if trying to burst him during her ally's disable.

* Heroes who rely on skills to become a heavy hitter in a certain amount of time can waste their timing because of a lucky Lucky Shot's disarm: Terrorblade, Sven, Clinkz, Windranger, Alchemist, Dragon Knight, Legion Commander

* Swashbuckle quickly burn away Refraction charges.
* Lucky Shot can possibly disrupt Templar Assassin when she is boosted with Refraction.
* Pangolier's abilities which does not need to target and has big area of effect allows him to damage her even during Meld.
* Pangolier's high mobility easily shrug off the slow from Psionic Trap.

* His Rot can force Templar Assassin out of her Meld and destroy all of her Refraction charges quickly, and her small health pool and meager defense make her very vulnerable to his Meat Hook without Refraction.

* Despite the armor reduction from Meld, Templar Assassin's reliance on physical damage and medium attack speed is unlikely to harm Dragon Knight.
* Templar Assassin's Refraction charges also get quickly removed by the damage over time from Dragon Knight's ultimate.
Additional:
* The damage over time from Dragon Knight's Elder Dragon Form rapidly burns down Refraction, allowing him to attack her. Also, Breathe Fire reduces Templar Assassin's damage and Dragon Tail is a stun with a considerable duration, letting him and his team whittle her health down once her defenses wear off.

* Tidebringer will deal lots of damage to Alchemist before he builds physical survivability items.
* Torrent and X Marks the Spot can control Alchemist at all stages of the game before he has Black King Bar.
* Ghostship's rum buff will greatly reduce the Alchemist's damage output in teamfights including his Radiance.

* Alchemist is a well-known Radiance carrier among other auras your illusions will benefit from. They also get the extra move speed and reduced base attack time from his Chemical Rage, and it's even better if you can catch him as his own rage is about to expire.
* Disruption will buy enough time for all allies to retreat when Alchemist starts to activate Unstable Concoction.

* Ember's magic damage build is able to burst down Alchemist due to his low strength gain and Alchemist's normal item pick up.

* Batrider's abilities are designed to deal damage over time, burning through Templar Assassin's layers extremely quickly. Flamebreak applies 7 instances of damage, burning through the entirety of Refraction, and Firefly applies damage on the place, forcing her to either get out of Meld and be attacked or stay in place or be incinerated.
Additional:
* Batrider's DoT damage quickly removes Templar Assassin's Refraction and can damage her during Meld.

* Untouchable greatly reduces Chemical Rage's attack speed advantage.

* Because Templar Assassin does not have escape potential in lane, any support hero with roaming potential and a Dust of Appearance can be great at shutting her down early game: Earth Spirit, Spirit Breaker, Tusk, Bounty Hunter, Riki, Warlock.

* Heroes with invisibility will be detected by Thirst when they have low enough health: Bounty Hunter, Templar Assassin, Riki, Clinkz, Weaver, Treant Protector, Nyx Assassin.

* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

* Visage can quickly kill heroes with low to medium base armor and no innate escape mechanism. Examples include Alchemist, Crystal Maiden and Zeus.

* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

* Because Templar Assassin does not have escape potential in lane, any support hero with roaming potential and a Dust of Appearance can be great at shutting her down early game: Earth Spirit, Spirit Breaker, Tusk, Bounty Hunter, Riki, Warlock.

* Because Templar Assassin does not have escape potential in lane, any support hero with roaming potential and a Dust of Appearance can be great at shutting her down early game: Earth Spirit, Spirit Breaker, Tusk, Bounty Hunter, Riki, Warlock.

* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

* Because Templar Assassin does not have escape potential in lane, any support hero with roaming potential and a Dust of Appearance can be great at shutting her down early game: Earth Spirit, Spirit Breaker, Tusk, Bounty Hunter, Riki, Warlock.

Additional:
* Templar Assassin is dependant on Refraction in teamfights. Because Magnetize deals damage per second and Earth Spirit is even able to refresh the duration of his ultimate he is suitable for wasting Refraction and allowing his team to take her down.

* Heroes that have disposable area-targeted spells can force her to undo her Meld: Leshrac, Puck, Tiny. An experienced Templar Assassin could try to Refraction before Meld so she can tank through those damage without getting her Blink disabled.

* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

Additional:
* Ensnare disables Lanaya's invisibility and Blink Dagger (a core item on Templar Assassin), and her illusions will break Refraction easily.

* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

* Because Templar Assassin does not have escape potential in lane, any support hero with roaming potential and a Dust of Appearance can be great at shutting her down early game: Earth Spirit, Spirit Breaker, Tusk, Bounty Hunter, Riki, Warlock.

* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Pugna

* As with other heroes mentioned in this section, Templar Assassin is not a hero that is fully "countered" by Crystal Maiden (the way she is against Viper and Jakiro), however, the proper combination and execution Crystal Maiden's spells, stacked with her team, can most certainly spell the end for Templar Assassin.
* Frostbite can quickly eat away Refraction charges, leaving Templar Assassin vulnerable for the rest of her team to kill.
* Freezing Field will still apply damage to Templar Assassin when she is under the effect of Meld, making it an even less viable form of escape until a Blink Dagger is purchased.
* Blink Dagger is also cancelled by all of Crystal Maiden's spells, and the fairly short cooldowns on Frostbite and Crystal Nova make her a great asset to a chase against Templar Assassin.
* This is not to say that Templar Assassin has any difficulty killing off the low armor, low HP pool Crystal Maiden, so fighting her alone is never advised.

* Ice Blast cancels out Chemical Rage's rapid health regeneration. It can also take advantage of Alchemist's Armlet of Mordiggian toggling, as it will make HP drain insanely fast, essentially killing the bearer in no time.
Additional:
* Ice Blast nullifies the health regeneration granted by Chemical Rage, which Alchemist greatly relies on to stay alive in battle.
* Alchemist tends to build Armlet of Mordiggian which can be deadly during Ice Blast.

* Chemical Rage will rarely save Alchemist against Ursa's Fury Swipes.
* Enrage allows Ursa to both be a threat to Alchemist and avoid his over time damage.

* Phantom Lancer's illusions destroy Refraction charges very quickly.

* Feast is good against high health strength heroes such as Alchemist.
* Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.

* Alchemist has very bad armor and does not build armor items for the large majority of his build, so Jingu Mastery and Wukong's Command can be very deadly.
* Desolator, Sange and Yasha or Diffusal Blade can all be purchased to increase your damage against Alchemist or just to keep your movement speed high enough to match him while Chemical Rage is active.
* Monkey King is an agility hero and scales with armor, so Acid Spray loses it's effectiveness later in the game.

* Heroes that have disposable area-targeted spells can force her to undo her Meld: Leshrac, Puck, Tiny. An experienced Templar Assassin could try to Refraction before Meld so she can tank through those damage without getting her Blink disabled.

* Melee heroes that get kited easily have hard times dealing with Puck without any lockdowns, as Puck is one of the most mobile heroes. Heroes like Sven, Lifestealer, Ursa and Alchemist may have problems to get to Puck without proper initiation items. They also lack reliable lockdowns, as their disables are easily avoidable for Puck, or are just a soft disable.