* Fury swipes can tear Dragon knight down as it stacks infinitely.

* Viscous Nasal Goo slows down Dragon Knight and lowers armor, locking him down and making him more vulnerable.

* Low armor and lack of escape makes Pudge vulnerable to Ursa, specially when he gets his Blink Dagger.
* If Pudge lands a Meat Hook on Ursa, Ursa can simply face Pudge head on provided he can burst him down before any follow up disables.
* Enrage's Aghanim's Scepter upgrade allows Ursa to dispel Pudge's Dismember.

* Pudge is particularly susceptible to Bristleback's Viscous Nasal Goo and Quill Spray due to his naturally low armor and poor agility gain.
* Bristleback, in combination with his strength gain, high health, common itemization for magic resistance and damage reduction from Bristleback makes him a poor target for Pudge.
Additional:
* Bristleback is one of the hardest heroes to gank with a Meat Hook and Dismember combo, and attempts to do so sometimes backfire on Pudge.

* Bristleback's tankiness and Bristleback allow him to outlast Burning Spears' damage-over-time at almost any point in the game. In addition, if Huskar chooses to cast Life Break on Bristleback, Bristleback can simply turn around before it hits and receive little damage.
* Viscous Nasal Goo will reduce Huskar's low armor even further, and Quill Spray and Warpath will tear him down extremely quickly.
Additional:
* The damage from Burning Spear can be reduced by turning away from Huskar.
* Bristleback can bait Huskar into using Life Break on him, then turn around and receive very little damage.

* Jumping on Ursa with Life Break is often suicide for Huskar, as he will be immediately bursted down with Fury Swipes.
Additional:
* Huskar likes fights with a long duration and is usually at low health, making him vulnerable against Ursa's physical damage.
* Jumping in with Life Break against Ursa is suicide, as Enrage, Overpower, and Fury Swipes will easily shred Huskar.

* Medusa's tankiness doesn't help her very much against Fury Swipes in long teamfights.
* With no escape mechanism and a slow movement speed, getting jumped on by Ursa usually spells a quick end for Medusa in the early game.
Additional:
* Ursa's status resistance from Enrage reduces Medusa's gaze.
* Ursa can stack damage with Fury Swipes easily against her Mana Shield in a prolonged team match.

* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.

* Tiny's nonexistent armor in the early game makes him very vulnerable to Quill Spray's large amounts of physical damage.
* Bristleback decreases Tiny's high burst damage against Bristleback.
* Viscous Nasal Goo can slow Tiny to a crawl and allows Bristleback to easily kite him with his high movement speed and Quill Spray's long range, as Tiny has no ability to escape.

* Due to Tiny's non-existent agility gain, high physical damage heroes are more effective against him (Clinkz, Templar Assassin, Ursa, Wraith King etc).

* All assassin-type carries in a one against one situation: Meepo, Phantom Assassin, Riki, Ursa. Luna's only chances are that she buys Ethereal Blade or Black King Bar to gain a slight edge against them, or both items if necessary.

* Quill Spray and Bristleback harass Luna more efficiently than she does with Lucent Beam.
* Bristleback helps return a lot of damage to Luna’s team if she uses her nukes on him and he has his back to her.
* Viscous Nasal Goo and Warpath are enough to outrun a speedy Luna.
* Bristleback tends to be a frequent carrier of Crimson Guard, which is good protection from bouncing glaives.
Additional:
* Multiple instances of damage from Eclipse will trigger Bristleback's passive repeatedly in a short time, dealing tremendous damage to Luna and her teammates.

* Bristleback's constant harass from Quill Spray will greatly hurt Enigma's laning and kill his Eidolons.

* Enigma lack burst damage, and that makes him vulnerable to heroes who can recover themselves and turn the fight around to their advantage after Enigma finishes his initiation: Faceless Void, Terrorblade, Ursa, Weaver, Broodmother, Slark, Abaddon, Wraith King, Lifestealer.

* If Ursa uses Enrage, Pugna's Life Drain is next to worthless against him, due to Ursa taking 80% less damage, therefor Pugna heals by only 20% of the damage that the spell deals.
* If Ursa jumps on you with a Blink Dagger he can easily wipe you out with Overpower.
* Ursa's Overpower can destroy a full health Nether Ward and still have a few swipes leftover, Also Ursa's low mana spells means he takes negligible damage from the Nether ward anyway.

* Ursa's massive physical damage can destroy Kunkka quickly.
* Enrage can be activated before being hit by Ghostship to prevent most of the damage.
* Earthshock slows Kunkka's movement speed. With no escape abilities, Kunkka is easy prey.

* Bristleback's abilities are nearly useless for Rubick to Spell Steal, as he does not gain the bonuses from Warpath.

* Quill Spray's constant AoE damage will hit Dark Willow even in Shadow Realm. Its automatic damage will hurt her if she tries to get close and use Bedlam.

* Enrage reduces the damage from Blade Mail and Counter Helix to a minimum, forcing Axe to play around Ursa's ultimate ability.
* Overpower and Fury Swipes stacks damage overwhelming for Axe, despite his high health.

* Heroes who can slow and kite Axe will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Earthshock prevents Shadow Fiend from escaping after Ursa used his Blink Dagger to get on top of him.
* Overpower and Fury Swipes allow Ursa to quickly kill Shadow Fiend.
* Enrage keeps Ursa alive in a manfight with Shadow Fiend and allows him to stay close, even if Shadow Fiend uses Requiem of Souls.

* Fury Swipes does not work on allies, mitigating a majority of Ursa's damage.
* Ursa's unimpressive attack speed and attack damage without Overpower and Fury Swipes means that he deals little to no damage to allies.
* Aghanim's Scepter upgraded Enrage allows Ursa to survive Winter Wyvern's initiation.

* Quill Spray is very effective against Io, as it has very low armor and has to stay close to the fight to not break its Tether.

* Macropyre's frequent damage ticks causes Bristleback to activate repeatedly, resulting in free damage as long as Bristleback faces away from Jakiro.

* Enrage will make it very difficult to burst him down.
* Zeus has little armor, HP and mobility; Ursa's favorite kind of target.

* Lifestealer can't fight Ursa in any stage of the game because of his high physical damage with Fury Swipes and Overpower.
Additional:
* Lifestealer's Feast will most likely not out-heal the damage from Fury Swipes and Overpower in the early to mid game.

* Heroes with high physical damage can damage Lifestealer more than he can heal: Bristleback, Clinkz, Luna,Shadow Fiend, Slardar {Hero ID:Terrorblade}

* Fury Swipes is not protected by Blade Fury and allows Ursa to harass Juggernaut anytime.
* Enrage reduces the damage taken from Omnislash.

* Fury Swipes damage is not reduced by Atrophy Aura, essentially bypassing Underlord's only natural defense.
* Enrage can quickly dispel the root of Pit of Malice.

* Fortune's End cannot dispel Warpath stacks on Bristleback or Quill Spray stacks on allies.
* Bristleback can heavily reduce Oracle's damage output. With it, Oracle may accidentally heal Bristleback with Purifying Flames, especially if Bristleback has bonus magic resistance.

* Viscous Nasal Goo can hinder Crystal Maiden's already abysmal mobility, which allows Bristleback (or his teammates) to run her down and kill her.
* Bristleback frequently builds Blade Mail, which can quickly kill Crystal Maiden if her ultimate is used while he is under its effect.
* The passive part of Bristleback will trigger many, many times under the damage from Freezing Field, and as the stacks increase, the damage output from each successive cast (or proc) will eat away at Crystal Maiden's small HP pool.

* Quill Spray usually hits Meepo's clones, although Bristleback cannot turn his back when rooted with Earthbind.

* Lone Druid and The Spirit Bear cannot burst down Bristleback due to Bristleback
* Bristleback can easily run to Lone Druid without any hesitation, with Viscous Nasal Goo to reduce armor and slow the Spirit Bear or Lone Druid and Quill Spray can deal damage to both Lone Druid and the Spirit Bear at the same time

* Fury Swipes will keep stacking on Tidehunter since it cannot be dispelled by Kraken Shell and its bonus damage cannot be reduced by Anchor Smash.
* Enrage dispels the slow from Gush, and if upgraded with Aghanim's Scepter, can even dispel Ravage's stun.

* Bristleback reduces most of Broodmother's and her spiderlings' damage.
* Quill Spray will hit any spiders in its proximity, hindering Broodmother's fighting and farming capabilities.
Additional:
* Quill Spray destroys spiderlings, and hits Broodmother even when she's regenerating in her webs. This makes Bristleback one of her hardest counters in lane.

* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe

* Heroes without an escape mechanism: Shadow Fiend, Alchemist

Additional:
* Chemical Rage will rarely save Alchemist against Ursa's Fury Swipes.
* Enrage allows Ursa to both be a threat to Alchemist and avoid his over time damage.

* Ursa can do damage very fast with his Overpower and Fury Swipes abilities, Necrohops will have taken large amounts of damage before he can use Ghost Shroud, And if Ursa has Skull Basher, Ursa will quickly demolish Necrophos before he can do anything to retaliate.
* Skilled and smart Ursa can bait Necrophos into using Reaper's Scythe on him, and with his Aghanim's Scepter upgraded Enrage that can negate 80% of the damage, Ursa will often survive and waste Reaper's Scythe.

* Enemies that possess high defenses through magic resistance, damage reduction, or high regeneration will make it difficult to whittle their health down to get to Reaper's Scythe's threshold. Such heroes include Bristleback (although only from behind), Spectre, Ursa, and Dragon Knight.

* Heroes with burst damage of their own won't be afraid to go toe to toe with Void Spirit, like Ursa, Lifestealer, or Axe.

* Ursa is a special mention because despite Bulwark diminishing most of the damage Ursa does, he is quite durable, especially with Enrage, discouraging the aggressive all-in playstyle of Mars; Ursa can simply not target Mars.

* Ursa can shred Warlock's Golems in a few seconds with Fury Swipes and Overpower.

* Bristleback's Viscous Nasal Goo can catch and slow Bounty Hunter. Warpath and Quill Spray can defeat him quickly due to his small HP pool when compared to Bristleback's.

* Ursa with Enrage
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Heroes with damage-over-time abilities will not only proc Bristleback's passive continuously, they will also do little harm to him when he is facing away from the source: Venomancer, Arc Warden

* Heroes with damage-over-time abilities will not only proc Bristleback's passive continuously, they will also do little harm to him when he is facing away from the source: Venomancer, Arc Warden

Additional:
* Arc Warden has relatively lower armor and mobility, which makes him an easy target to apply Quill Spray and Viscous Nasal Goo stacks.
* Arc Warden also does not like to build a Silver Edge as it takes a long time to build up and may slow down the timings for other important items needed in the game. (eg. an Orchid Malevolence versus a Storm Spirit)
* However, do note that in a game where your team has many jumping capabilities or good passives, like a Tidehunter or Spectre, a Silver Edge becomes incredibly valuable on Arc Warden as not only can he run away from the jumps, he effectively gets 2 breaks, and Bristleback may not be the best pick.

* Ursa can deal lots of damage during the laning phase before Terrorblade can have Sunder available.
* Even if Terrorblade succeeds to use Sunder on Ursa, Enrage's damage reduction can help Ursa survive after Terrorblade has used Sunder him while also making Terrorblade's attacks tickle, even during Metamorphosis for it's duration.

* Enrage with Aghanim's Scepter can dispel Flaming Lasso.

* Light Strike Array has a long delay, making her vulnerable for Ursa's burst.
* Enrage can protect Ursa against Lina's high magical burst.

* Quill Spray will hit Sand King inside Sand Storm, damaging him and putting Sand King's Blink Dagger on cooldown, preventing him from escaping.
* Epicenter's numerous damage ticks will trigger Bristleback's passive repeatedly during teamfights.

* Ursa can easily unleash a number of attacks in an incredibly short amount of time, easily destroying the Supernova in a couple of seconds regardless of Fire Spirits' debuff. His Enrage also dampens any damage Phoenix might toss at his direction, as well as remove any debuffs Phoenix may place on him.

* Ursa's high physical burst damage combined with his big attack speed and durability makes him a very bad target for Power Cogs.
* Even with Blade Mail, Ursa's Enrage will negate most of the reflected damage.

* Timbersaw's physical survivability revolves around Reactive Armor, which is largely ignored by Fury Swipes due to the extreme amounts of damage it does in a very few number of attacks.
* Timbersaw's burst damage will not do much against Enrage, although he could easily use Timber Chain to escape, wasting the duration of it.

* Bristleback, Centaur Warrunner, Spirit Breaker, Pudge, Huskar: These heroes are too tanky for Puck to burst down. Also, all of them have spells which can deal with and shut Puck down reliably.

* Quill Spray quickly destroys Chaos Knight's Phantasms.

* Heroes who continue dealing damage while being stunned: Luna, Razor, Axe, Bristleback, Leshrac,

* Heroes with stronger lane presence that can threaten to kill him: Batrider, Juggernaut, Ursa, Monkey King, Razor.

* Bristleback's tankiness and damage reduction from the rear makes him very hard for Phantom Lancer to chase and finish off, due to his lack of burst damage.
* Quill Spray destroys Phantom Lancer's illusions.
* Bristleback's passive costs no mana, meaning that it will continue to trigger even if Phantom Lancer drains Bristleback's mana with Diffusal Blade.
Additional:
* Bristleback's tankiness and damage reduction from the rear makes him very hard for Phantom Lancer to chase and finish off, due to his lack of burst damage.
* Quill Spray quickly destroys Phantom Lancer's illusions.
* Bristleback's passive costs no mana, meaning that it will continue to trigger even if Phantom Lancer drains Bristleback's mana with Diffusal Blade.

* Silencer relies on preventing enemies from using abilities in teamfights with Arcane Curse, Last Word, and Global Silence. However, they are ineffective against Ursa since he relies more on items and attacks than abilities.
* Against a carry Silencer, Enrage can help Ursa reduce all damage he takes, even Glaives of Wisdom's pure damage will just tickle Ursa while his Enrage is active.

* The bonus Backstab damage from Cloak and Dagger is rendered irrelevant with Bristleback and hurts Riki more than him because of the passive Quill Spray.
* Riki can still get damaged by Bristleback's Quill Spray while invisible, and it can be hard to deal with in lane.
* Bristleback is not too bothered by Smoke Screen. Though he cannot use Quill Spray manually inside it, it still procs passively when he takes damage from the back. The movement speed from Warpath allows him to get out of the area easily.
* Due to Bristleback's natural tankiness, he is an ideal Gem of True Sight carrier.
* Riki rarely buys Silver Edge to break Bristleback's passive because the invisibility aspect of it is redundant.
Additional:
* Quill Spray will hit Riki even when he is invisible.
* Cloak and Dagger's bonus backstab damage is rendered irrelevant against Bristleback.
* Smoke Screen does not stop Bristleback's passive from activating.
* Due to Bristleback's natural tankiness, he is an ideal Gem of True Sight carrier, directly countering Riki's invisibility.

* Quill Spray can be used to kill Lycan's summons.
* Bristleback allows him to stay alive against Lycan while dishing out counter attacks
* He can overpower Lycan with his Warpath instead.
Additional:
* Lycan's wolves deal little damage to Bristleback, and are easily killed by Quill Spray, even when they're invisible.
* Lycan's lack of burst damage makes it very hard for him to kill Bristleback, especially when his back is turned.