* Ice Blast prevents Io from healing the target.
Additional:
* Ice Blast prevents Io from healing an ally with Tether and prevents healing from Overcharge
* Io is a common Mekansm builder which is useless if he is affected by Ice Blast.

* Ice Blast nullifies the healing from {U:Warlock Golem} and Shadow Word.
* Cold Feet stuns Warlock if he chooses to continue channeling Upheaval.

* Thirst allows Bloodseeker to see where Io relocated to, should either Io or the tethered hero have low health.
* Rupture forces Io to stay in place, preventing it from using the Tether bonus movement speed to escape.

* Blood Rite can silence Warlock, which as a spellcaster is bad for him.
* Rupture prevents Warlock from moving without taking damage, which due to his general lack of escapes is bad for him, and when combined with Blood Rite can be a very lethal combo.

* Shapeshift allows Lycan to escape from Upheaval with 650 movement speed.
* Warlock doesn't have a lot of AoE abilities to deal with Lycan's wolves from Summon Wolves.

* Heroes with low armor and little mobility, like Huskar, Io, etc. will also have an unfortunate fate.

* Charge of Darkness can be used to escape or counter-initiate against a Relocate gank.
* Greater Bash and Nether Strike is devastating due to Io's low armor, and can even knock it away from tethered target.

* Warlock is a very strong hero when positioned correctly, and his long cast range helps him with this. However, some Heroes might disrupt or sneakily pass through your allies and deal with you, preventing you from doing your job. Such heroes include Chaos Knight, Spirit Breaker, Riki, and some others.

* Because all of Warlock's abilities are active abilities, silences can make his impact in fights minimal. Be cautious of heroes that carry silences like Death Prophet, Puck, and the aforementioned Silencer.

* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer

* Warlock is a very strong hero when positioned correctly, and his long cast range helps him with this. However, some Heroes might disrupt or sneakily pass through your allies and deal with you, preventing you from doing your job. Such heroes include Chaos Knight, Spirit Breaker, Riki, and some others.

* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper

* Impale interrupts Upheaval.
* Nyx Assassin Vendetta allows him to escape from Warlock's Upheaval with maximum move speed.
* Warlock's low health pool and mobility can easily take down by Nyx Assassin's burst damage.

* Strafe and Searing Arrows allow Clinkz to quickly kill Io due to its low armor.

* Surge allows for Dark Seer and his allies to escape from Upheaval due to it ignoring any slow.

* Lucent Beam can cancel Tether and Relocate.
* Moon Glaives and Eclipse make short work of Io and its tethered ally.

* Weaver's Shukuchi allows him to escape from Warlock's Upheaval with high move speed.
* His ultimate Time Lapse allows him to ignore damage from {U:Warlock Golem} and escape.

* Lightning Storm will usually hit both Io and its tethered target since both will be close enough for the lightning to jump.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and its tethered target.
Additional:
* Lightning Storm will usually hit both Io and his Tethered target since both will be close enough for the lightning to jump. It can then be followed up by Split Earth.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and his Tethered target.

* Ignite has long duration damage-over-time and prevents Io from healing his Tethered ally.

* Living Armor can be used to save a hero from a Relocate gank.

* Glimpse directly negates Relocate.
Additional:
* Disruptor can always Glimpse back Io or his target after he Relocated nearby.
* Even better, thanks to the indicator on the ground, you can even preemptively drop Static Storm and Kinetic Field on the spot they will relocate to.
* Thunder Strike and Glimpse are also good tools to bring back an Io that Tethered away in the fog of war.

* Cold Embrace can render the extra attack speed from Overcharge meaningless.
* Splinter Blast and Winter's Curse are very affective against Io, as it has to stay close to its tethered hero.

* Because Warlock's abilities are all active abilities, Silencer can make his impact minimal.
* Arcane Curse prevents Warlock from using his abilities without taking 56/84/112/140 damage, and slowed by 9%/12%/15%/18%.
* Last Word can prevent Warlock from casting his combo.
* Global Silence can nullify Warlock's impact in fights and prevent him from getting any spells off.

* Mana Break prevents Warlock from casting his spells.
* Blink allows Anti-Mage to escape from Upheaval.
* Counterspell reduces damage from Shadow Word and the {U:Warlock Golem}'s Permanent Immolation.
* Mana Void deals heavy damage after Chaotic Offering and interrupts Upheaval.

* Lich's Chain Frost forces Io to give up providing buff to his ally with Tether or suffer devastating damage with his tethered ally.
* Lich could easily use Sinister Gaze to disable Io from getting away with Tether or Relocate.

* Upheaval does not interrupt Slark too much, as he can just Pounce out of the area.
* Fatal Bonds and Shadow Word can be dispelled by Dark Pact.

* Grimstroke can catch Io and his ally easily with SoulBind as Io has a tendency to tether himself with an ally frequently.
* Io is highly vulnerable to disables. Hence, Grimstroke's Phantom's Embrace is a great ability to hinder Io's potential.
Additional:
* Soulbind can target both Io and its Tethered ally, allowing Grimstroke and his team to target both with single target spells. Should Io try to Relocate, Phantom's Embrace can stop its channel to prevent escape.

* A pre-placed Fire Remnant allows Ember Spirit to escape Upheaval.
* Flame Guard blocks Shadow Word's damage.
* Sleight of Fist allows Ember Spirit to attack from range, ignoring Upheaval, and Searing Chains lets him interrupt it.

* Quill Spray is very effective against Io, as it has very low armor and has to stay close to the fight to not break its Tether.

* Phantom Strike allows Phantom Assassin jump directly to Io.
* Coup de Grace makes short work of Io's low health and armor.

* Ghostship helps your team soak up damage from Chaotic Offering and hit summons hard.
* Tidebringer clears summons later in the game.
* Most of your spells can interrupt Upheaval.

* With God's Strength, Warlock Golem goes down in a matter of seconds. The two weaker golems granted by Aghanim's Scepter will fare worse due to Great Cleave hitting both.
* Storm Hammer upgraded with level 15 talent dispels Shadow Word.
Additional:
* God's Strength combined with Great Cleave destroys Chaotic Offering golems within seconds.

* Fragile heroes: Bounty Hunter has decent nuking capabilities with Shiruken Toss and Jinada thus making fragile heroes easy picks for ganking. Few examples of such heroes are:Crystal Maiden, Pugna, Skywrath Mage, Io, Witch Doctor, etc.

* Because all of Warlock's abilities are active abilities, silences can make his impact in fights minimal. Be cautious of heroes that carry silences like Death Prophet, Puck, and the aforementioned Silencer.

* Warlock is a very strong hero when positioned correctly, and his long cast range helps him with this. However, some Heroes might disrupt or sneakily pass through your allies and deal with you, preventing you from doing your job. Such heroes include Chaos Knight, Spirit Breaker, Riki, and some others.

* Ursa can shred {U:Warlock Golem}s in a few seconds with Fury Swipes and Overpower.

* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer

* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Squishy heroes (Io, Crystal Maiden, Lina...), as Earth Spirit can deal tons of damage with Magnetize.

* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer

* Duel is very effective against Io due to its low health and armor.

* Heroes who rely on summons will see them destroyed easily by Overwhelming Odds: Lycan, Arc Warden, Warlock, Chen

* Squishy heroes, usually supports, like Io, Ancient Apparition, Keeper of the Light etc can die instantly from Tiny's magic burst.

* Take Aim and Assassinate allow Sniper to reach Io even if it stays in the backline.